WO1997032038A3 - Dna-sequence-based diagnosis of mastitis from a milk sample - Google Patents

Dna-sequence-based diagnosis of mastitis from a milk sample Download PDF

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Publication number
WO1997032038A3
WO1997032038A3 PCT/FI1997/000126 FI9700126W WO9732038A3 WO 1997032038 A3 WO1997032038 A3 WO 1997032038A3 FI 9700126 W FI9700126 W FI 9700126W WO 9732038 A3 WO9732038 A3 WO 9732038A3
Authority
WO
WIPO (PCT)
Prior art keywords
mastitis
dna sequence
dna
milk sample
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FI1997/000126
Other languages
French (fr)
Other versions
WO1997032038A2 (en
Inventor
Jouko Tapani Alatossava
Anu Kyllik Tilsala-Timisjaervi
Paeivi Tuulikki Forsman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oulutech Ltd
Original Assignee
Oulutech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oulutech Ltd filed Critical Oulutech Ltd
Priority to EP97905172A priority Critical patent/EP1012328A2/en
Priority to NZ332047A priority patent/NZ332047A/en
Priority to AU18819/97A priority patent/AU716675B2/en
Publication of WO1997032038A2 publication Critical patent/WO1997032038A2/en
Publication of WO1997032038A3 publication Critical patent/WO1997032038A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A rapid method for diagnosing mastitis is described. The method is based on DNA sequence identification comprising the steps of determining the presence of the following DNA sequences in a milk sample: a DNA sequence specific for somatic cells for indicating inflammation; a DNA sequence specific for a mastitis pathogen for indicating infection; and a DNA sequence specific for an antibiotic-resistance-encoding gene of a pathogen for assisting a proper drug therapy. Test kits and genus- or species-specific oligonucleotides and their use in said method are also described.
PCT/FI1997/000126 1996-02-27 1997-02-26 Dna-sequence-based diagnosis of mastitis from a milk sample Ceased WO1997032038A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP97905172A EP1012328A2 (en) 1996-02-27 1997-02-26 Dna-sequence-based diagnosis of mastitis from a milk sample
NZ332047A NZ332047A (en) 1996-02-27 1997-02-26 Dna-sequenced-based diagnosis of mastitis from a milk sample
AU18819/97A AU716675B2 (en) 1996-02-27 1997-02-26 DNA-sequence-based diagnosis of mastitis from a milk sample

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/607,384 US5849488A (en) 1996-02-27 1996-02-27 DNA-sequence-based diagnosis of mastitis from a milk sample
US08/607,384 1996-02-27

Publications (2)

Publication Number Publication Date
WO1997032038A2 WO1997032038A2 (en) 1997-09-04
WO1997032038A3 true WO1997032038A3 (en) 1997-10-09

Family

ID=24432042

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI1997/000126 Ceased WO1997032038A2 (en) 1996-02-27 1997-02-26 Dna-sequence-based diagnosis of mastitis from a milk sample

Country Status (5)

Country Link
US (1) US5849488A (en)
EP (1) EP1012328A2 (en)
AU (1) AU716675B2 (en)
NZ (1) NZ332047A (en)
WO (1) WO1997032038A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1091004B1 (en) * 1994-06-24 2009-02-25 Innogenetics N.V. Simultaneous detection, identification and differentiation of Mycobacterium species using a hybridization assay
JPH11146799A (en) * 1997-09-10 1999-06-02 Snow Brand Milk Prod Co Ltd New primers and their use
WO2000066788A2 (en) 1999-05-03 2000-11-09 Gen-Probe Incorporated Polynucleotide probes for detection and quantitation of staphylococcus
US6821770B1 (en) * 1999-05-03 2004-11-23 Gen-Probe Incorporated Polynucleotide matrix-based method of identifying microorganisms
DE10113815A1 (en) * 2001-03-21 2002-10-02 Eppendorf Ag Process for the isolation of plasmids or proteins from suspended bacterial or yeast cells
JP2003189869A (en) * 2001-12-27 2003-07-08 Nisshinbo Ind Inc Method for determining biological species contained in a subject and kit used therefor
US20080059330A1 (en) * 2002-02-07 2008-03-06 Micro Beef Technologies, Ltd. Livestock management systems and methods
EP1426447A1 (en) * 2002-12-06 2004-06-09 Roche Diagnostics GmbH Method for the detection of pathogenic gram positive bacteria selected from the genera Staphylococcus, Enterococcus and Streptococcus
US20060115819A1 (en) * 2002-12-06 2006-06-01 Sofie Claeys Detection, identification and differentiation of eubacterial taxa using a hybridization assay
US7718361B2 (en) * 2002-12-06 2010-05-18 Roche Molecular Systems, Inc. Quantitative test for bacterial pathogens
JP4377375B2 (en) * 2002-12-06 2009-12-02 エフ．ホフマン−ラ ロシュ アーゲー Multiple analytical detection of pathogenic organisms
US20070111205A1 (en) * 2003-07-25 2007-05-17 Delwiche Micheal J Detection of somatic cells in milk
CA2565981C (en) 2004-05-13 2015-02-17 Advanced Animal Diagnostics Microfluidic device and leucocyte antigen mediated microfluidic assay
EP1977001A4 (en) * 2006-01-20 2009-12-02 Genein Co Ltd Oligonucleotide for detection of bacteria associated with sepsis and microarrays and a methods for detection of the bacteria using the oligonucleotide
US20090233329A1 (en) * 2006-03-24 2009-09-17 Rodriguez Rodolfo R Microfluidic chamber assembly for mastitis assay
WO2009036956A1 (en) * 2007-09-19 2009-03-26 University Of Bern Detection of staphylococcus aureus in bovine mastitic milk
US20090191561A1 (en) * 2007-12-31 2009-07-30 Finnzymes Oy Methods and oligonucleotides for detection of mastitis causing bacteria
FI20075976A0 (en) 2007-12-31 2007-12-31 Finnzymes Oy Methods and oligonucleotides for detecting bacteria that cause mastitis
CN110237880A (en) 2013-01-18 2019-09-17 生米公司 Analytical equipment
CN105765363B (en) 2013-11-01 2020-05-08 生米公司 Sample extraction and preparation device
US20180077894A1 (en) * 2016-09-22 2018-03-22 Src, Inc. Methods and systems for detection and tracking of mastitis in dairy cattle
JP7293236B2 (en) 2017-09-15 2023-06-19 バイオミーム インコーポレイテッド Method and system for automated sample processing
CN111712581A (en) 2017-12-15 2020-09-25 生米公司 Portable device and method for analyzing samples
WO2019143812A1 (en) * 2018-01-18 2019-07-25 Biomeme, Inc. Methods of assaying for the presence of microorganisms
EP3942281A4 (en) 2019-03-21 2022-11-16 Biomeme, Inc. Multi-function analytic devices
CN110669838B (en) * 2019-10-22 2022-07-05 山东省农业科学院奶牛研究中心 Application of LGR4 as cow mastitis prevention, diagnosis or treatment marker
WO2022061105A1 (en) 2020-09-18 2022-03-24 Biomeme, Inc. Portable devices and methods for analyzing samples

Citations (3)

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WO1992000317A1 (en) * 1990-07-02 1992-01-09 Promega Corporation Method and kit for the separation, concentration and analysis of cells
EP0527628A1 (en) * 1991-08-13 1993-02-17 Eli Lilly And Company Rapid method for detection of methicillin-resistant staphylococci
WO1996000298A1 (en) * 1994-06-24 1996-01-04 Innogenetics N.V. Simultaneous detection, identification and differentiation of eubacterial taxa using a hybridization assay

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0452596A1 (en) * 1990-04-18 1991-10-23 N.V. Innogenetics S.A. Hybridization probes derived from the spacer region between the 16S and 23S rRNA genes for the detection of non-viral microorganisms
US5536638A (en) * 1990-04-18 1996-07-16 N.V. Innogenetics S.A. Hybridization probes derived from the spacer region between the 16S and 23S rRNA genes for the detection of Neisseria gonorrhoeae
FI90788C (en) * 1992-03-11 1994-03-25 Futekno Oy Determination of cell numbers in milk with specific nucleic acid probes
EP0725142B1 (en) * 1994-06-24 2003-09-10 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for producing d-amino acid by using composite immobilized enzyme preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000317A1 (en) * 1990-07-02 1992-01-09 Promega Corporation Method and kit for the separation, concentration and analysis of cells
EP0527628A1 (en) * 1991-08-13 1993-02-17 Eli Lilly And Company Rapid method for detection of methicillin-resistant staphylococci
WO1996000298A1 (en) * 1994-06-24 1996-01-04 Innogenetics N.V. Simultaneous detection, identification and differentiation of eubacterial taxa using a hybridization assay

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BENTLEY R ET AL: "DEVELOPMENT AND USE OF SPECIES-SPECIFIC OLIGONUCLEOTIDE PROBES FOR THE DIFFERENTIATION OF STREPTOCOCCUS UBERIS AND STREPTOCOCCUS PARAUBERIS", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 31, no. 1, January 1993 (1993-01-01), pages 57 - 60, XP000675362 *
DATABASE WPI Week 9347, Derwent World Patents Index; AN 93-370751, XP002032801 *
GILLESPIE, B ET AL: "Polymerase based DNA fingerprinting method for the identification of streptococcus species from bovine milk", JOURNAL OF DAIRY SCIENCE., vol. 78, no. suppl.1, 25 June 1995 (1995-06-25), pages 172, XP000674569 *
KNEIFEL, W ET AL.: "Adaption of two commercially avaible DNA probes for the detection of E.coli and Staphylococcus aureus to selected fields of dairy hygiene", ZENTRALBLATT FÜR HYGIENE UND UMWELTMEDIZIN, vol. 192, no. 6, March 1992 (1992-03-01), pages 544 - 53, XP000675359 *
LAM T ET AL: "Epidermiological characteristics of bovine clinical mastitis caused by Staphylococcus aureus and Escherichia coli studied by DNA fingerprinting", AM. J. VET. RES, vol. 57, no. 1, January 1996 (1996-01-01), pages 39 - 42, XP000675357 *

Also Published As

Publication number Publication date
NZ332047A (en) 1999-07-29
AU1881997A (en) 1997-09-16
WO1997032038A2 (en) 1997-09-04
AU716675B2 (en) 2000-03-02
US5849488A (en) 1998-12-15
EP1012328A2 (en) 2000-06-28

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