WO1997044451A3 - Vasoactive amine binding molecules - Google Patents

Vasoactive amine binding molecules Download PDF

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Publication number
WO1997044451A3
WO1997044451A3 PCT/GB1997/001372 GB9701372W WO9744451A3 WO 1997044451 A3 WO1997044451 A3 WO 1997044451A3 GB 9701372 W GB9701372 W GB 9701372W WO 9744451 A3 WO9744451 A3 WO 9744451A3
Authority
WO
WIPO (PCT)
Prior art keywords
binding molecules
amine binding
vasoactive
vasoactive amine
hbp1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB1997/001372
Other languages
French (fr)
Other versions
WO1997044451A2 (en
Inventor
Guido Christian Paesen
Patricia Ann Nuttall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford Vacs Ltd
Original Assignee
Oxford Vacs Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9610484.9A external-priority patent/GB9610484D0/en
Priority claimed from GBGB9707844.8A external-priority patent/GB9707844D0/en
Priority to DK97923204T priority Critical patent/DK0906425T3/en
Priority to AT97923204T priority patent/ATE290078T1/en
Priority to HK99104344.7A priority patent/HK1019158B/en
Priority to NZ332648A priority patent/NZ332648A/en
Priority to BR9709101A priority patent/BR9709101A/en
Priority to EP97923204A priority patent/EP0906425B1/en
Application filed by Oxford Vacs Ltd filed Critical Oxford Vacs Ltd
Priority to DE69732630T priority patent/DE69732630T2/en
Priority to CA2253924A priority patent/CA2253924C/en
Priority to JP54179997A priority patent/JP4209466B2/en
Priority to AU29071/97A priority patent/AU725630B2/en
Publication of WO1997044451A2 publication Critical patent/WO1997044451A2/en
Publication of WO1997044451A3 publication Critical patent/WO1997044451A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43527—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from ticks
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

According to the present invention, there are provided vasoactive amine binding proteins (VABPs) that specifically bind to vasoactive amines with a dissociation constant of less than 10-7 M and which belong to the same protein family as MS-HBP1, FS-HBP1, FS-HBP2 and D.RET6.
PCT/GB1997/001372 1996-05-18 1997-05-19 Vasoactive amine binding molecules Ceased WO1997044451A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP54179997A JP4209466B2 (en) 1996-05-18 1997-05-19 Vasoactive amine binding molecule
AU29071/97A AU725630B2 (en) 1996-05-18 1997-05-19 Vasoactive amine binding molecules
DE69732630T DE69732630T2 (en) 1996-05-18 1997-05-19 VASOACTIVE, AMINBINDING MOLECULES
HK99104344.7A HK1019158B (en) 1996-05-18 1997-05-19 Vasoactive amine binding molecules
NZ332648A NZ332648A (en) 1996-05-18 1997-05-19 Vasoactive amine binding proteins (VABP) and vasoactive amine binding molecules (VABM)
BR9709101A BR9709101A (en) 1996-05-18 1997-05-19 Vasoactive amine-binding protein nucleic acid molecule cloning or expression vector transgenic animal host cell process of preparing a protein and using a vasoactive amine-binding protein
EP97923204A EP0906425B1 (en) 1996-05-18 1997-05-19 Vasoactive amine binding molecules
DK97923204T DK0906425T3 (en) 1996-05-18 1997-05-19 Vasoactive amine binding molecules
AT97923204T ATE290078T1 (en) 1996-05-18 1997-05-19 VASOACTIVE, AMINE-BINDING MOLECULES
CA2253924A CA2253924C (en) 1996-05-18 1997-05-19 Vasoactive amine binding molecules

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9610484.9 1996-05-18
GBGB9610484.9A GB9610484D0 (en) 1996-05-18 1996-05-18 Bioregulators
GBGB9707844.8A GB9707844D0 (en) 1997-04-18 1997-04-18 Vasoactive amine binding molecules
GB9707844.8 1997-04-18

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09/618,919 Continuation US6617312B1 (en) 1996-05-18 2000-07-18 Vasoactive amine binding molecules

Publications (2)

Publication Number Publication Date
WO1997044451A2 WO1997044451A2 (en) 1997-11-27
WO1997044451A3 true WO1997044451A3 (en) 1998-02-19

Family

ID=26309363

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1997/001372 Ceased WO1997044451A2 (en) 1996-05-18 1997-05-19 Vasoactive amine binding molecules

Country Status (15)

Country Link
US (1) US6617312B1 (en)
EP (1) EP0906425B1 (en)
JP (1) JP4209466B2 (en)
CN (1) CN1198927C (en)
AT (1) ATE290078T1 (en)
AU (1) AU725630B2 (en)
BR (1) BR9709101A (en)
CA (1) CA2253924C (en)
CU (1) CU23164A3 (en)
DE (1) DE69732630T2 (en)
DK (1) DK0906425T3 (en)
ES (1) ES2236807T3 (en)
NZ (1) NZ332648A (en)
PT (1) PT906425E (en)
WO (1) WO1997044451A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU763299B2 (en) * 1997-11-26 2003-07-17 Evolutec Limited Histamine and serotonin binding molecules
GB9920673D0 (en) 1999-09-01 1999-11-03 Evolutec Limited Treatment of allergic rhinitis
GB9920674D0 (en) * 1999-09-01 1999-11-03 Evolutec Limited Treatment of conjunctivitis
GB0307544D0 (en) * 2003-04-01 2003-05-07 Evolutec Ltd Treatment method
GB0522298D0 (en) 2005-11-01 2005-12-07 Natural Environment Res Agents that bind IgE
GB0809279D0 (en) * 2008-05-21 2008-06-25 Varleigh Ltd Histamine binding protein
GB0816976D0 (en) * 2008-09-16 2008-10-22 Natural Environment Res Council Protein
GB201004850D0 (en) 2010-03-23 2010-05-05 Natural Environment Res Council Proteins
EP2710383B1 (en) 2011-05-16 2017-01-11 The University of Newcastle Performance of a biomarker panel for irritable bowel syndrome
GB201720505D0 (en) * 2017-12-08 2018-01-24 Volution Immuno Pharmaceuticals Sa Methods for treatment of neuropathic pain
CN119390803B (en) * 2025-01-02 2025-03-04 鄂尔多斯市中心医院（内蒙古自治区超声影像研究所） Tick-derived histamine binding protein HqHBP and application of encoding gene thereof in antiallergic reaction

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2283239A (en) * 1993-10-29 1995-05-03 Ucb Sa Human H1 histamine receptor
WO1996011271A1 (en) * 1994-10-07 1996-04-18 Heska Corporation Novel ectoparasite saliva proteins and apparatus to collect such proteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2283239A (en) * 1993-10-29 1995-05-03 Ucb Sa Human H1 histamine receptor
WO1996011271A1 (en) * 1994-10-07 1996-04-18 Heska Corporation Novel ectoparasite saliva proteins and apparatus to collect such proteins

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
RIBEIRO J. AND WALKER F.: "High affinity histamine-binding and antihistaminic activity of the salivary nitric oxide-carrying heme protein (nitrophorin) of Rhodnius prolixus", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 180, December 1994 (1994-12-01), pages 2251 - 2257, XP002050815 *
WANG H. AND NUTTALL P.: "Comparison of the proteins in salivary glands, saliva and haemolymph of Rhipicephalus appendiculatus female ticks during feeding", PARASITOLOGY, vol. 109, no. pt.4, November 1994 (1994-11-01), pages 517 - 523, XP002050816 *

Also Published As

Publication number Publication date
EP0906425B1 (en) 2005-03-02
CN1198927C (en) 2005-04-27
NZ332648A (en) 2000-05-26
HK1019158A1 (en) 2000-01-14
DE69732630D1 (en) 2005-04-07
ATE290078T1 (en) 2005-03-15
AU725630B2 (en) 2000-10-19
BR9709101A (en) 1999-08-03
PT906425E (en) 2005-05-31
JP2000512489A (en) 2000-09-26
EP0906425A2 (en) 1999-04-07
CN1225683A (en) 1999-08-11
JP4209466B2 (en) 2009-01-14
US6617312B1 (en) 2003-09-09
CU23164A3 (en) 2006-08-24
WO1997044451A2 (en) 1997-11-27
CA2253924C (en) 2012-03-06
CA2253924A1 (en) 1997-11-27
DK0906425T3 (en) 2005-07-11
DE69732630T2 (en) 2005-12-29
ES2236807T3 (en) 2005-07-16
AU2907197A (en) 1997-12-09

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