WO1998005682A3 - Peptides corresponding or imitating at least one antigenic determinant of the hamagglutinin protein of mobillivirus - Google Patents

Peptides corresponding or imitating at least one antigenic determinant of the hamagglutinin protein of mobillivirus Download PDF

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Publication number
WO1998005682A3
WO1998005682A3 PCT/EP1997/004070 EP9704070W WO9805682A3 WO 1998005682 A3 WO1998005682 A3 WO 1998005682A3 EP 9704070 W EP9704070 W EP 9704070W WO 9805682 A3 WO9805682 A3 WO 9805682A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
antigenic determinant
hamagglutinin
mobillivirus
imitating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1997/004070
Other languages
French (fr)
Other versions
WO1998005682A2 (en
Inventor
Claude P Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to EP97942832A priority Critical patent/EP0920449B1/en
Priority to AT97942832T priority patent/ATE226594T1/en
Priority to DE69716609T priority patent/DE69716609T2/en
Priority to AU44528/97A priority patent/AU4452897A/en
Publication of WO1998005682A2 publication Critical patent/WO1998005682A2/en
Publication of WO1998005682A3 publication Critical patent/WO1998005682A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Peptides having an amino acid sequence corresponding to or mimicking at least one antigenic determinant of at least one structural protein of a morbillivirus, vaccines comprising such peptides, and a method for provoking an immune response to morbillivirus in mammals are disclosed. More particularly, peptides and antigenic determinants comprising at least a part of the amino acid sequence corresponding to amino acids 226 to 255 or 361 to 420 of the hemagglutinin protein of the Edmonston strain of MV or a portion, variation, or mutant or mimotope or conjugate of any such sequences are disclosed.
PCT/EP1997/004070 1996-07-31 1997-07-26 Peptides corresponding or imitating at least one antigenic determinant of the hamagglutinin protein of mobillivirus Ceased WO1998005682A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP97942832A EP0920449B1 (en) 1996-07-31 1997-07-26 Morbillivirus-derived peptides
AT97942832T ATE226594T1 (en) 1996-07-31 1997-07-26 PEPTIDES DERIVED FROM THE MORBILLIVIRUS
DE69716609T DE69716609T2 (en) 1996-07-31 1997-07-26 PEPTIDES DERIVED FROM THE MORBILLIVIRUS
AU44528/97A AU4452897A (en) 1996-07-31 1997-07-26 Peptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96112341 1996-07-31
EP96112341.1 1996-07-31

Publications (2)

Publication Number Publication Date
WO1998005682A2 WO1998005682A2 (en) 1998-02-12
WO1998005682A3 true WO1998005682A3 (en) 1998-08-06

Family

ID=8223060

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1997/004070 Ceased WO1998005682A2 (en) 1996-07-31 1997-07-26 Peptides corresponding or imitating at least one antigenic determinant of the hamagglutinin protein of mobillivirus

Country Status (5)

Country Link
EP (1) EP0920449B1 (en)
AT (1) ATE226594T1 (en)
AU (1) AU4452897A (en)
DE (1) DE69716609T2 (en)
WO (1) WO1998005682A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2880043A1 (en) * 2020-05-20 2021-11-23 Fundacion Para El Fomento De La Investig Sanitaria Y Biomedica De La Comunitat Valenciana Fisabio PEPTIDE FOR USE IN THE PREVENTION AND/OR TREATMENT OF A DISEASE CAUSED BY A VIRUS THAT AFFECTS THE RESPIRATORY TRACT (Machine-translation by Google Translate, not legally binding)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0540135A2 (en) * 1991-10-14 1993-05-05 The Kitasato Institute Attenuated measles vaccine virus strain containing specific nucleotide sequence and a method for its absolute identification

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0540135A2 (en) * 1991-10-14 1993-05-05 The Kitasato Institute Attenuated measles vaccine virus strain containing specific nucleotide sequence and a method for its absolute identification

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
FOURNIER PH. ET AL.: "Antibodies to a new linear site at the topographical or functional interface between the haemagglutin and fusion proteins protect against measles encephalitis", J. GENERAL VIROLOGY, vol. 78, 6 June 1997 (1997-06-06), pages 1295 - 1302, XP002062541 *
OBEID E.O. ET AL.: "Analysis of th antigenic profile of measles virus haemagglutinin in mice and humans using overlypping synthesis peptides", VIRUS RESEARCH, vol. 32, 1994, pages 69 - 84, XP002062540 *
ROTA J.S. ET AL.: "Comparison of sequences of the H, F, and N coding genes of measles virus vaccine strains", VIRUS RESEARCH, vol. 31, 1994, pages 317 - 330, XP002062543 *
ZIEGLER D. ET AL.: "Protection against measles virus encephalitis by monoclonal antibodies binding to a cystein loop domain of the H protein mimicked by peptides which are not recognized by maternal antibodies", J. GENERAL VIROLOGY, vol. 77, 10 October 1996 (1996-10-10), pages 2479 - 2489, XP002062542 *

Also Published As

Publication number Publication date
DE69716609D1 (en) 2002-11-28
EP0920449A2 (en) 1999-06-09
AU4452897A (en) 1998-02-25
ATE226594T1 (en) 2002-11-15
WO1998005682A2 (en) 1998-02-12
EP0920449B1 (en) 2002-10-23
DE69716609T2 (en) 2003-07-03

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