WO1998015355A3 - Tool and method for transfer of drops - Google Patents

Tool and method for transfer of drops Download PDF

Info

Publication number
WO1998015355A3
WO1998015355A3 PCT/US1997/018037 US9718037W WO9815355A3 WO 1998015355 A3 WO1998015355 A3 WO 1998015355A3 US 9718037 W US9718037 W US 9718037W WO 9815355 A3 WO9815355 A3 WO 9815355A3
Authority
WO
WIPO (PCT)
Prior art keywords
support
drops
tool
wettable
areas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1997/018037
Other languages
French (fr)
Other versions
WO1998015355A2 (en
Inventor
Thierry L A Dannoux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corning Inc
Original Assignee
Corning Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9612375A external-priority patent/FR2754469B1/en
Application filed by Corning Inc filed Critical Corning Inc
Priority to EP97909988A priority Critical patent/EP1011862A4/en
Priority to JP10517656A priority patent/JP2001502057A/en
Priority to AU47471/97A priority patent/AU4747197A/en
Publication of WO1998015355A2 publication Critical patent/WO1998015355A2/en
Publication of WO1998015355A3 publication Critical patent/WO1998015355A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0262—Drop counters; Drop formers using touch-off at substrate or container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0845—Filaments, strings, fibres, i.e. not hollow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1037—Using surface tension, e.g. pins or wires

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The tool (1, 3) is designed for the transport of drops (2i) which are arranged according to a predetermined spatial distribution. It comprises at least one filiform support (1) mounted on a frame (3) clearing this support, said support presenting a plurality of the areas wettable by said liquid, distributed according to a predetermined distribution over its length, these wettable areas being separated from each other by nonwettable sections of said support (1). Application to cell cultures or tests on biological molecules.
PCT/US1997/018037 1996-10-10 1997-10-03 Tool and method for transfer of drops Ceased WO1998015355A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP97909988A EP1011862A4 (en) 1996-10-10 1997-10-03 Tool for the transport of liquid drops and method for the transfer of drops using such a tool
JP10517656A JP2001502057A (en) 1996-10-10 1997-10-03 Device for transferring droplets and method for transferring droplets using such device
AU47471/97A AU4747197A (en) 1996-10-10 1997-10-03 Tool for the transport of liquid drops and method for the transfer of drops using such a tool

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR96/12375 1996-10-10
FR9612375A FR2754469B1 (en) 1996-10-10 1996-10-10 LIQUID DROP TRANSPORT TOOL AND METHOD FOR TRANSFERRING DROPS USING SUCH A TOOL
US3923897P 1997-02-28 1997-02-28
US60/039,238 1997-02-28

Publications (2)

Publication Number Publication Date
WO1998015355A2 WO1998015355A2 (en) 1998-04-16
WO1998015355A3 true WO1998015355A3 (en) 1998-07-02

Family

ID=26233033

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/018037 Ceased WO1998015355A2 (en) 1996-10-10 1997-10-03 Tool and method for transfer of drops

Country Status (5)

Country Link
EP (1) EP1011862A4 (en)
JP (1) JP2001502057A (en)
CN (1) CN1234112A (en)
AU (1) AU4747197A (en)
WO (1) WO1998015355A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884626B1 (en) 1998-04-27 2005-04-26 Corning Incorporated Redrawn capillary imaging reservoir
US9078426B2 (en) 2004-04-08 2015-07-14 Biomatrica, Inc. Integration of sample storage and sample management for life science
US9376709B2 (en) 2010-07-26 2016-06-28 Biomatrica, Inc. Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309600B1 (en) * 1997-08-28 2001-10-30 Biotrove, Inc. Apparatus for droplet microchemistry
EP0955084B1 (en) 1998-04-27 2006-07-26 Corning Incorporated Method of depositing an array of biological samples using a redrawn capillary reservoir
DE19827754C1 (en) 1998-06-23 2000-02-10 Graffinity Pharm Design Gmbh Device for the almost simultaneous synthesis of a large number of samples
US6762061B1 (en) 1998-07-03 2004-07-13 Corning Incorporated Redrawn capillary imaging reservoir
GB9821573D0 (en) * 1998-10-02 1998-11-25 Central Research Lab Ltd Method and apparatus for removing a substance from a container
GB9824202D0 (en) * 1998-11-04 1998-12-30 Moore David F Liquid transfer system
CA2358566A1 (en) 1999-01-08 2000-07-13 Charles S. Vann Fiber array for contacting chemical species and methods for using and making same
US7595189B2 (en) 1999-01-08 2009-09-29 Applied Biosystems, Llc Integrated optics fiber array
WO2000058735A2 (en) * 1999-03-31 2000-10-05 Optigon Technologies High throughput screening apparatus and methods for arraying microparticles
US6977145B2 (en) 1999-07-28 2005-12-20 Serono Genetics Institute S.A. Method for carrying out a biochemical protocol in continuous flow in a microreactor
US6399396B1 (en) * 2000-01-28 2002-06-04 Agilent Technologies, Inc. Compressed loading apparatus and method for liquid transfer
US7588725B2 (en) 2001-04-25 2009-09-15 Biotrove, Inc. High throughput autosampler
US8414774B2 (en) 2001-04-25 2013-04-09 Agilent Technologies, Inc. Systems and methods for high-throughput screening of fluidic samples
WO2009059286A1 (en) 2007-11-02 2009-05-07 Biotrove, Inc. Devices and methods for coupling mass spectrometry devices with chromatography systems
US6812030B2 (en) 2001-04-25 2004-11-02 Biotrove, Inc. System and method for high throughput sample preparation and analysis using column chromatography
US9845489B2 (en) 2010-07-26 2017-12-19 Biomatrica, Inc. Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
WO2012117083A2 (en) 2011-03-03 2012-09-07 F. Hoffmann-La Roche Ag Hanging droplet plate
US9725703B2 (en) 2012-12-20 2017-08-08 Biomatrica, Inc. Formulations and methods for stabilizing PCR reagents
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
CN106572650B (en) 2014-06-10 2021-08-31 生物马特里卡公司 Stabilizes thrombocytes at ambient temperature
JP2017532974A (en) * 2014-10-29 2017-11-09 コーニング インコーポレイテッド Apparatus and method for generating and culturing 3D cell aggregates
WO2016069930A1 (en) 2014-10-29 2016-05-06 Corning Incorporated Microwell design and fabrication for generation of cell culture aggregates
JP6930914B2 (en) 2014-10-29 2021-09-01 コーニング インコーポレイテッド Perfusion bioreactor platform
EP3212759A1 (en) 2014-10-29 2017-09-06 Corning Incorporated Cell culture insert
SG11201804776SA (en) 2015-12-08 2018-07-30 Biomatrica Inc Reduction of erythrocyte sedimentation rate
JP7195302B2 (en) 2017-07-14 2022-12-23 コーニング インコーポレイテッド Cell culture vessel for 3D culture and method for culturing 3D cells
EP3652290B1 (en) 2017-07-14 2022-05-04 Corning Incorporated 3d cell culture vessels for manual or automatic media exchange
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
JP7197557B2 (en) 2017-07-14 2022-12-27 コーニング インコーポレイテッド Cell culture vessel with porous support
CN108167281B (en) * 2017-12-05 2019-07-19 西北工业大学 A kind of accessible guidance method of drop based on porous water absorbent fiber
WO2020013847A1 (en) 2018-07-13 2020-01-16 Corning Incorporated Microcavity dishes with sidewall including liquid medium delivery surface
CN111065725B (en) 2018-07-13 2024-03-29 康宁股份有限公司 Fluidic device comprising microplates with interconnected walls
WO2020013845A1 (en) 2018-07-13 2020-01-16 Corning Incorporated Cell culture vessels with stabilizer devices

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4008154A (en) * 1974-03-29 1977-02-15 Exxon Research And Engineering Company Rotary filter wash distributor
US4111553A (en) * 1976-03-30 1978-09-05 Unisearch Limited Multi-sample transporting and heating apparatus for use in atomic absorption spectrometry
US4396287A (en) * 1981-05-04 1983-08-02 Leeman Labs Inc. Sample manipulation system for spectrometers
US5012195A (en) * 1989-12-28 1991-04-30 Abb Power T&D Company, Inc. Method for improving the electrical strength of vapor-mist dielectrics
US5519218A (en) * 1993-08-04 1996-05-21 Chang; On Kok Sample holder for spectroscopy

Family Cites Families (6)

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US3572558A (en) * 1969-01-02 1971-03-30 Robert M Hooker Dropper dispenser
GB1320426A (en) * 1971-07-06 1973-06-13 Pfizer Multiple solution testing device
IT983328B (en) * 1973-06-12 1974-10-31 Gasbarro L EQUIPMENT FOR BIOLOGICAL ANALYSIS THAT FOR EXAMPLE ON THE BLOOD SERUM AND OTHER WITH CONTAINERS AND MEANS OF COLLECTION OF MULTI PLI SAMPLE SUITABLE TO ENSURE UNIFORMITY OF SAMPLE
US5334837A (en) * 1991-10-05 1994-08-02 Horiba, Ltd. Micro analytical method, sampling plate used in same, method of detecting organic compound by use of said micro analytical method, apparatus for same and method of dividing for micro-liquid flow
SE9203320D0 (en) * 1992-11-06 1992-11-06 Pharmacia Lkb Biotech A METHOD OF PROCESSING NUCLEIC ACID SAMPLES
US5551487A (en) * 1995-03-10 1996-09-03 Hewlett-Packard Company Micro-dispenser for preparing assay plates

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4008154A (en) * 1974-03-29 1977-02-15 Exxon Research And Engineering Company Rotary filter wash distributor
US4111553A (en) * 1976-03-30 1978-09-05 Unisearch Limited Multi-sample transporting and heating apparatus for use in atomic absorption spectrometry
US4396287A (en) * 1981-05-04 1983-08-02 Leeman Labs Inc. Sample manipulation system for spectrometers
US5012195A (en) * 1989-12-28 1991-04-30 Abb Power T&D Company, Inc. Method for improving the electrical strength of vapor-mist dielectrics
US5519218A (en) * 1993-08-04 1996-05-21 Chang; On Kok Sample holder for spectroscopy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1011862A4 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884626B1 (en) 1998-04-27 2005-04-26 Corning Incorporated Redrawn capillary imaging reservoir
US9078426B2 (en) 2004-04-08 2015-07-14 Biomatrica, Inc. Integration of sample storage and sample management for life science
US9376709B2 (en) 2010-07-26 2016-06-28 Biomatrica, Inc. Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures

Also Published As

Publication number Publication date
AU4747197A (en) 1998-05-05
WO1998015355A2 (en) 1998-04-16
EP1011862A2 (en) 2000-06-28
CN1234112A (en) 1999-11-03
JP2001502057A (en) 2001-02-13
EP1011862A4 (en) 2000-06-28

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