WO1998024483A3 - Biodegradable polymeric film - Google Patents

Biodegradable polymeric film Download PDF

Info

Publication number
WO1998024483A3
WO1998024483A3 PCT/US1997/022552 US9722552W WO9824483A3 WO 1998024483 A3 WO1998024483 A3 WO 1998024483A3 US 9722552 W US9722552 W US 9722552W WO 9824483 A3 WO9824483 A3 WO 9824483A3
Authority
WO
WIPO (PCT)
Prior art keywords
films
polymeric film
biodegradable polymeric
implants
biocompatibility
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1997/022552
Other languages
French (fr)
Other versions
WO1998024483A2 (en
Inventor
Neil C Leatherbury
Kristine Kieswetter
Michael A Slivka
Gabriele Niederauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osteobiologics Inc
Original Assignee
Osteobiologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osteobiologics Inc filed Critical Osteobiologics Inc
Priority to JP52587698A priority Critical patent/JP2001505114A/en
Priority to AU55968/98A priority patent/AU5596898A/en
Priority to EP97952332A priority patent/EP1018982B1/en
Priority to DE69732721T priority patent/DE69732721T2/en
Priority to CA002274004A priority patent/CA2274004A1/en
Publication of WO1998024483A2 publication Critical patent/WO1998024483A2/en
Publication of WO1998024483A3 publication Critical patent/WO1998024483A3/en
Priority to US09/305,546 priority patent/US6514286B1/en
Anticipated expiration legal-status Critical
Priority to US10/353,719 priority patent/US20030114937A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

This invention provides biodegradable, biocompatible polymeric films having uniform selected thicknesses between about 60 micrometers and about 5 mm useful in the manufacture of therapeutic implants for insertion into a patient's body. The films may be shaped to cover implants made of other materials to improve their biocompatibility. The films may be coated with or incorporate bioactive agents. They may have differing properties, e.g., porosity, thickness, and degradation rate, in different areas.
PCT/US1997/022552 1996-12-03 1997-12-03 Biodegradable polymeric film Ceased WO1998024483A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP52587698A JP2001505114A (en) 1996-12-03 1997-12-03 Biodegradable polymer membrane
AU55968/98A AU5596898A (en) 1996-12-03 1997-12-03 Biodegradable polymeric film
EP97952332A EP1018982B1 (en) 1996-12-03 1997-12-03 Biodegradable polymeric film
DE69732721T DE69732721T2 (en) 1996-12-03 1997-12-03 BIODEGRADABLE ARTIFICIAL FILMS
CA002274004A CA2274004A1 (en) 1996-12-03 1997-12-03 Biodegradable polymeric film
US09/305,546 US6514286B1 (en) 1996-12-03 1999-05-05 Biodegradable polymeric film
US10/353,719 US20030114937A1 (en) 1996-12-03 2003-01-28 Biodegradable polymeric film

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3208596P 1996-12-03 1996-12-03
US60/032,085 1996-12-03

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09/305,546 Continuation US6514286B1 (en) 1996-12-03 1999-05-05 Biodegradable polymeric film

Publications (2)

Publication Number Publication Date
WO1998024483A2 WO1998024483A2 (en) 1998-06-11
WO1998024483A3 true WO1998024483A3 (en) 1998-10-22

Family

ID=21863020

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/022552 Ceased WO1998024483A2 (en) 1996-12-03 1997-12-03 Biodegradable polymeric film

Country Status (8)

Country Link
US (2) US6514286B1 (en)
EP (1) EP1018982B1 (en)
JP (1) JP2001505114A (en)
AU (1) AU5596898A (en)
CA (1) CA2274004A1 (en)
DE (1) DE69732721T2 (en)
ES (1) ES2238736T3 (en)
WO (1) WO1998024483A2 (en)

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EP1018982B1 (en) 2005-03-09
US6514286B1 (en) 2003-02-04
ES2238736T3 (en) 2005-09-01
AU5596898A (en) 1998-06-29
WO1998024483A2 (en) 1998-06-11
EP1018982A2 (en) 2000-07-19
US20030114937A1 (en) 2003-06-19
DE69732721T2 (en) 2006-05-18
JP2001505114A (en) 2001-04-17
EP1018982A4 (en) 2002-06-26
DE69732721D1 (en) 2005-04-14
CA2274004A1 (en) 1998-06-11

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