WO1998025955A3 - Cloned glucagon-like peptide-2 receptors - Google Patents

Cloned glucagon-like peptide-2 receptors Download PDF

Info

Publication number
WO1998025955A3
WO1998025955A3 PCT/CA1997/000969 CA9700969W WO9825955A3 WO 1998025955 A3 WO1998025955 A3 WO 1998025955A3 CA 9700969 W CA9700969 W CA 9700969W WO 9825955 A3 WO9825955 A3 WO 9825955A3
Authority
WO
WIPO (PCT)
Prior art keywords
receptors
peptide
glucagon
nucleotides
cloned
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CA1997/000969
Other languages
French (fr)
Other versions
WO1998025955A9 (en
WO1998025955A2 (en
Inventor
Donald G Munroe
Ashwani K Gupta
Tejal B Vyas
Kirk Mccallum
Ermi Fan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allelix Biopharmaceuticals Inc
Original Assignee
Allelix Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/845,546 external-priority patent/US6077949A/en
Priority to DK97951013T priority Critical patent/DK0946591T3/en
Priority to US09/331,127 priority patent/US7473537B1/en
Priority to JP52605098A priority patent/JP4106094B2/en
Priority to CA2274989A priority patent/CA2274989C/en
Priority to AU54712/98A priority patent/AU722821B2/en
Priority to DE69737561T priority patent/DE69737561T2/en
Priority to EP97951013A priority patent/EP0946591B1/en
Application filed by Allelix Biopharmaceuticals Inc filed Critical Allelix Biopharmaceuticals Inc
Publication of WO1998025955A2 publication Critical patent/WO1998025955A2/en
Publication of WO1998025955A3 publication Critical patent/WO1998025955A3/en
Publication of WO1998025955A9 publication Critical patent/WO1998025955A9/en
Priority to DKPA199900825A priority patent/DK177593B1/en
Anticipated expiration legal-status Critical
Priority to US12/272,615 priority patent/US8592553B2/en
Priority to US14/068,992 priority patent/US20140248641A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention relates to nucleotides and amino acid sequences encoding glucagon-like peptide 2 receptors, recombinant host cells transformed with such nucleotides, and methods of using the same in drug screening and related applications.
PCT/CA1997/000969 1996-12-13 1997-12-15 Cloned glucagon-like peptide-2 receptors Ceased WO1998025955A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
DK97951013T DK0946591T3 (en) 1996-12-13 1997-12-15 Cloned glucagon-like peptide-2 receptors
US09/331,127 US7473537B1 (en) 1996-12-13 1997-12-15 Cloned glucagon-like peptide-2 receptors
JP52605098A JP4106094B2 (en) 1996-12-13 1997-12-15 Cloned glucagon-like peptide 2 receptor
CA2274989A CA2274989C (en) 1996-12-13 1997-12-15 Cloned glucagon-like peptide-2 receptors
AU54712/98A AU722821B2 (en) 1996-12-13 1997-12-15 Cloned glucagon-like peptide-2 receptors
DE69737561T DE69737561T2 (en) 1996-12-13 1997-12-15 CLONED GLUCAGON-SIMILAR PEPTIDE-2 RECEPTORS
EP97951013A EP0946591B1 (en) 1996-12-13 1997-12-15 Cloned glucagon-like peptide-2 receptors
DKPA199900825A DK177593B1 (en) 1996-12-13 1999-06-11 Isolated recombinant polynucleotide encoding a GLP-2 receptor and a method for identifying GLP-2 receptor ligands
US12/272,615 US8592553B2 (en) 1996-12-13 2008-11-17 Cloned glucagon-like peptide-2 receptors
US14/068,992 US20140248641A1 (en) 1996-12-13 2013-10-31 Cloned glucagon-like peptide-2 receptors

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US76722496A 1996-12-13 1996-12-13
US08/767,224 1996-12-13
US78772197A 1997-01-24 1997-01-24
US08/787,721 1997-01-24
US08/845,546 1997-04-24
US08/845,546 US6077949A (en) 1996-12-13 1997-04-24 Cloned glucagon-like peptide 2 receptors

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US76722496A Continuation 1996-12-13 1996-12-13

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US09/331,127 A-371-Of-International US7473537B1 (en) 1996-12-13 1997-12-15 Cloned glucagon-like peptide-2 receptors
US12/272,615 Division US8592553B2 (en) 1996-12-13 2008-11-17 Cloned glucagon-like peptide-2 receptors

Publications (3)

Publication Number Publication Date
WO1998025955A2 WO1998025955A2 (en) 1998-06-18
WO1998025955A3 true WO1998025955A3 (en) 1998-07-30
WO1998025955A9 WO1998025955A9 (en) 1998-10-15

Family

ID=27419634

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA1997/000969 Ceased WO1998025955A2 (en) 1996-12-13 1997-12-15 Cloned glucagon-like peptide-2 receptors

Country Status (9)

Country Link
EP (1) EP0946591B1 (en)
JP (1) JP4106094B2 (en)
AT (1) ATE358682T1 (en)
AU (1) AU722821B2 (en)
CA (1) CA2274989C (en)
DE (1) DE69737561T2 (en)
DK (2) DK0946591T3 (en)
ES (1) ES2287959T3 (en)
WO (1) WO1998025955A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8592553B2 (en) 1996-12-13 2013-11-26 Nps Pharmaceuticals, Inc. Cloned glucagon-like peptide-2 receptors
GB9930882D0 (en) * 1999-12-30 2000-02-23 Nps Allelix Corp GLP-2 formulations
AU4675901A (en) * 2000-04-13 2001-10-30 1149336 Ontario Inc. Glp-2 receptor gene promoter and uses thereof
ES2310192T3 (en) 2000-09-18 2009-01-01 Sanos Bioscience A/S USE OF GLP-2 PEPTIDES.
US7371721B2 (en) 2000-09-18 2008-05-13 Sanos Bioscience A/S Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes
WO2019086559A1 (en) 2017-10-31 2019-05-09 Adocia Composition comprising a glp-2 receptor agonist and a co-polyamino acid carrying carboxylate charges and hydrophobic radicals

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019175A1 (en) * 1992-03-25 1993-09-30 Bernard Thorens Receptor for the glucagon-like-peptide-1 (glp-1)
WO1995004821A1 (en) * 1993-08-09 1995-02-16 Merck & Co., Inc. Human glucagon-like 1 peptide receptor
WO1996032414A1 (en) * 1995-04-14 1996-10-17 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019175A1 (en) * 1992-03-25 1993-09-30 Bernard Thorens Receptor for the glucagon-like-peptide-1 (glp-1)
WO1995004821A1 (en) * 1993-08-09 1995-02-16 Merck & Co., Inc. Human glucagon-like 1 peptide receptor
WO1996032414A1 (en) * 1995-04-14 1996-10-17 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DRUCKER D J ET AL: "INDUCTION OF INTESTINAL EPITHELIAL PROLIFERATION BY GLUCAGON-LIKE PEPTIDE 2", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 93, 1990, pages 7911 - 7916, XP000650124 *

Also Published As

Publication number Publication date
DK0946591T3 (en) 2007-08-13
ES2287959T3 (en) 2007-12-16
DK199900825A (en) 1999-08-04
JP2001507571A (en) 2001-06-12
ATE358682T1 (en) 2007-04-15
CA2274989C (en) 2012-01-31
DK177593B1 (en) 2013-11-11
EP0946591B1 (en) 2007-04-04
AU722821B2 (en) 2000-08-10
DE69737561T2 (en) 2008-03-06
JP4106094B2 (en) 2008-06-25
WO1998025955A2 (en) 1998-06-18
CA2274989A1 (en) 1998-06-18
AU5471298A (en) 1998-07-03
DE69737561D1 (en) 2007-05-16
EP0946591A2 (en) 1999-10-06

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