WO1998032079A1 - Verfahren zur detektion von synchronizität zwischen mehreren digitalen messreihen mit hilfe eines rechners - Google Patents
Verfahren zur detektion von synchronizität zwischen mehreren digitalen messreihen mit hilfe eines rechners Download PDFInfo
- Publication number
- WO1998032079A1 WO1998032079A1 PCT/DE1998/000173 DE9800173W WO9832079A1 WO 1998032079 A1 WO1998032079 A1 WO 1998032079A1 DE 9800173 W DE9800173 W DE 9800173W WO 9832079 A1 WO9832079 A1 WO 9832079A1
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- Prior art keywords
- synchronicity
- discriminatory
- statistics
- series
- order
- Prior art date
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
- G06F17/10—Complex mathematical operations
- G06F17/18—Complex mathematical operations for evaluating statistical data, e.g. average values, frequency distributions, probability functions, regression analysis
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N3/00—Computing arrangements based on biological models
- G06N3/02—Neural networks
- G06N3/04—Architecture, e.g. interconnection topology
- G06N3/049—Temporal neural networks, e.g. delay elements, oscillating neurons or pulsed inputs
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F2218/00—Aspects of pattern recognition specially adapted for signal processing
- G06F2218/12—Classification; Matching
Definitions
- the invention relates to a method for the detection of synchronicity between several digital measurement series with the aid of a computer.
- Figure 1 serves to illustrate this.
- Three time series ZR1, ZR2 and ZR3 are given as examples. These time series can originate, for example, from different neurons or generally represent any binary frequency data.
- Order 0 defines how many time series are taken into account for synchronicity. In FIG. 1, the order 0 is 3. A probability for synchronicity should therefore be given for all possible combinations of the binary groupings of order 3 occurring in the example.
- a combination Patl (Oll) is shown in Figure 1, which occurs twice.
- the object on which the invention is based is to create a method for the detection of synchronicity between a number of digital measurement series, the method being particularly suitable for the detection of neuronal coding patterns in the brain. This object is achieved by the method according to the features of patent claim 1.
- the method formulates a nonparametric statistical approach to redundancy between several digital
- Detect series of measurements can involve the synchronous firing of several neurons.
- the synchronicity is detected by measuring a discriminatory significance, which tests a null hypothesis of independent fire using a surrogate method.
- the surrogate data used correspond to the null hypothesis of a non-causal relationship between the firing or the non-firing of several groups of neurons.
- a rejection of the null hypothesis is based on the calculation of the discriminatory statistics ⁇ of the original data set and the discriminatory statistics Dgi of the i th surrogate data set, which was generated assuming the null hypothesis.
- an exemplary development of the method according to the invention can be firing of several neurons on the basis of the measurement series, the number of which determines the order 0.
- the method according to the invention can thus solve the difficult problem of detecting neuronal coding patterns in the brain.
- FIG. 1 shows, by way of example, measurement data from different time series
- FIG. 2 shows a block diagram which represents the steps of the method according to the invention.
- Figure 2 illustrates a block diagram showing the individual
- K- a frequency of the occurrence of a possible binary combination j of the order under consideration and S (K) denote a number of the values of the series of measurements.
- R (..) a redundancy, x, y, z tuple of order i consisting of values of
- the null hypothesis P * is determined in step 2c in accordance with
- A is a set representing the arrangement of binary data in a tuple, the order of which is determined by the maximum number of '1' and
- the disturbance variable w is determined so that the discriminatory statistics ⁇ from the null hypothesis result in zero, ie
- surrogate data sets that is to say any instances of the regulation of the null hypothesis, are determined by a random generator (step 2d).
- series of measurements are "diced", the "cube” for each possible combination having the probability of occurrence determined by the null hypothesis.
- step 2e To decide whether there is synchronicity or not, a significance S is determined (step 2e):
- Surrogate data set generated by the null hypothesis ⁇ g an estimated mean of the discriminatory statistics of the surrogate data set, ⁇ s an estimated variance of the discriminating ones
- an advantageous application of the method according to the invention is the use of measurement series which are based on the firing of real neurons.
- the method can equally be applied to any binary frequency data.
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- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Data Mining & Analysis (AREA)
- Theoretical Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Mathematical Physics (AREA)
- General Engineering & Computer Science (AREA)
- Pure & Applied Mathematics (AREA)
- Computational Mathematics (AREA)
- Mathematical Analysis (AREA)
- Mathematical Optimization (AREA)
- Life Sciences & Earth Sciences (AREA)
- Software Systems (AREA)
- Artificial Intelligence (AREA)
- Computational Linguistics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Databases & Information Systems (AREA)
- Probability & Statistics with Applications (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Operations Research (AREA)
- Health & Medical Sciences (AREA)
- Evolutionary Biology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Algebra (AREA)
- Evolutionary Computation (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Computing Systems (AREA)
- Image Analysis (AREA)
- Complex Calculations (AREA)
- Testing, Inspecting, Measuring Of Stereoscopic Televisions And Televisions (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Indication And Recording Devices For Special Purposes And Tariff Metering Devices (AREA)
- Apparatus For Radiation Diagnosis (AREA)
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Abstract
Description
Claims
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98907836A EP0954802B1 (de) | 1997-01-21 | 1998-01-21 | Verfahren zur detektion von synchronizität zwischen mehreren digitalen physikalischen messreihen mit hilfe eines rechners |
| JP53328598A JP2001508899A (ja) | 1997-01-21 | 1998-01-21 | コンピュータを用いて複数のデジタル測定列間のシンクロニシティを検出する方法 |
| DE59800846T DE59800846D1 (de) | 1997-01-21 | 1998-01-21 | Verfahren zur detektion von synchronizität zwischen mehreren digitalen physikalischen messreihen mit hilfe eines rechners |
| AT98907836T ATE202228T1 (de) | 1997-01-21 | 1998-01-21 | Verfahren zur detektion von synchronizität zwischen mehreren digitalen physikalischen messreihen mit hilfe eines rechners |
| US09/319,347 US6134510A (en) | 1997-01-21 | 1998-01-21 | Method for detecting synchronicity between several digital measurement series with the aid of a computer |
| IL13012698A IL130126A0 (en) | 1997-01-21 | 1998-01-21 | Method for detecting synchronicity between several digital measurement series with the aid of a computer |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19701931.5 | 1997-01-21 | ||
| DE19701931A DE19701931C1 (de) | 1997-01-21 | 1997-01-21 | Verfahren zur Detektion von Synchronizität zwischen mehreren digitalen Meßreihen mit Hilfe eines Rechners |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1998032079A1 true WO1998032079A1 (de) | 1998-07-23 |
Family
ID=7817898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/DE1998/000173 Ceased WO1998032079A1 (de) | 1997-01-21 | 1998-01-21 | Verfahren zur detektion von synchronizität zwischen mehreren digitalen messreihen mit hilfe eines rechners |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6134510A (de) |
| EP (1) | EP0954802B1 (de) |
| JP (1) | JP2001508899A (de) |
| AT (1) | ATE202228T1 (de) |
| DE (2) | DE19701931C1 (de) |
| IL (1) | IL130126A0 (de) |
| WO (1) | WO1998032079A1 (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7674796B2 (en) | 2002-12-20 | 2010-03-09 | Pfizer Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19825070C1 (de) * | 1998-06-04 | 2000-01-05 | Ericsson Telefon Ab L M | Verfahren zur Bestimmung eines eine Variation zwischen einer meßbaren Größe und einer meßbaren Referenzgröße repräsentierenden Wertes |
| US6516288B2 (en) | 1999-12-22 | 2003-02-04 | Curtis A. Bagne | Method and system to construct action coordination profiles |
| DE10008251A1 (de) * | 2000-02-23 | 2001-08-30 | Gordon Pipa | Verfahren zum Erfassen und Auswerten von Korrelationen |
| US6839655B2 (en) | 2001-05-25 | 2005-01-04 | University Of Chicago | System for monitoring non-coincident, nonstationary process signals |
| US6718221B1 (en) | 2002-05-21 | 2004-04-06 | University Of Kentucky Research Foundation | Nonparametric control chart for the range |
| US6980875B1 (en) | 2003-05-21 | 2005-12-27 | University Of Kentucky Research Foundation | Nonparametric control chart for the range |
| EP3977305A4 (de) * | 2019-06-02 | 2023-01-25 | NParbor, Inc. | Verfahren und vorrichtung zur gemeinsamen detektion von querstromereignissen |
| DE102020201568A1 (de) | 2020-02-08 | 2021-08-12 | Robert Bosch Gesellschaft mit beschränkter Haftung | Verfahren zum Verarbeiten von Sensordaten einer Sensorik eines Fahrzeugs |
| US11538592B2 (en) | 2020-12-15 | 2022-12-27 | Bagne-Miller Enterprises, Inc. | Complex adaptive systems metrology by computation methods and systems |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4844086A (en) * | 1987-04-13 | 1989-07-04 | The Children's Medical Center Corporation | Cross correlation analysis in brain electrical activity mapping |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2690541B1 (fr) * | 1992-04-28 | 1994-06-17 | Bull Sa | Procede d'elaboration automatique d'une representation implicite des impliquants premiers d'une fonction. |
| FR2697652B1 (fr) * | 1992-10-30 | 1994-12-16 | Bull Sa | Procédé de détermination automatique des probabilités associées à une fonction booléenne. |
| US5684726A (en) * | 1996-06-24 | 1997-11-04 | International Business Machines Corporation | Firing method & apparatus for random ESD testing |
| US5987398A (en) * | 1998-04-30 | 1999-11-16 | Sony Corporation | Method and apparatus for statistical process control of machines and processes having non-constant mean of a response variable |
-
1997
- 1997-01-21 DE DE19701931A patent/DE19701931C1/de not_active Expired - Fee Related
-
1998
- 1998-01-21 US US09/319,347 patent/US6134510A/en not_active Expired - Fee Related
- 1998-01-21 WO PCT/DE1998/000173 patent/WO1998032079A1/de not_active Ceased
- 1998-01-21 IL IL13012698A patent/IL130126A0/xx unknown
- 1998-01-21 DE DE59800846T patent/DE59800846D1/de not_active Expired - Fee Related
- 1998-01-21 EP EP98907836A patent/EP0954802B1/de not_active Expired - Lifetime
- 1998-01-21 JP JP53328598A patent/JP2001508899A/ja active Pending
- 1998-01-21 AT AT98907836T patent/ATE202228T1/de not_active IP Right Cessation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4844086A (en) * | 1987-04-13 | 1989-07-04 | The Children's Medical Center Corporation | Cross correlation analysis in brain electrical activity mapping |
Non-Patent Citations (4)
| Title |
|---|
| DECO G ET AL: "TRAINING DATA SELECTION BY DETECTING PREDICTABILITY IN NON-STATIONARY TIME SERIES BY A SURROGATE-CUMULANT BASED APPROACH", PROCEEDINGS INTERNATIONAL WORKSHOP ON NEURAL NETWORKS FOR IDENTIFICATION, CONTROL, ROBOTICS, AND SIGNAL/IMAGE PROCESSING, 21 August 1996 (1996-08-21), pages 11 - 19, XP000676844 * |
| MARTIGNON L ET AL: "Detecting and measuring higher order synchronization among neurons: a Bayesian approach", ARTIFICIAL NEURAL NETWORKS - ICANN 96. 1996 INTERNATIONAL CONFERENCE PROCEEDINGS, ARTIFICIAL NEURAL NETWORKS - ICANN 96, BOCHUM, GERMANY, 16-19 JULY 1996, ISBN 3-540-61510-5, 1996, BERLIN, GERMANY, SPRINGER-VERLAG, GERMANY, pages 401 - 407, XP002065030 * |
| MARTIGNON L ET AL: "Learning exact patterns of quasi-synchronization among spiking neurons from data on multi-unit recordings", PROCEEDINGS OF THE 1996 CONFERENCE, ADVANCES IN NEURAL INFORMATION PROCESSING SYSTEMS 9. PROCEEDINGS OF THE 1996 CONFERENCE, DENVER, CO, USA, 2-5 DEC. 1996, ISBN 0-262-10065-7, 1997, LONDON, UK, MIT PRESS, UK, pages 76 - 82, XP002064968 * |
| TEICH M C ET AL: "TEMPORAL CORRELATION IN CAT STRIATE-CORTEX NEURAL SPIEK TRAINS", IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE, vol. 15, no. 5, September 1996 (1996-09-01), pages 79 - 87, XP000625354 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7674796B2 (en) | 2002-12-20 | 2010-03-09 | Pfizer Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| US7741336B2 (en) | 2002-12-20 | 2010-06-22 | Pfizer Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
Also Published As
| Publication number | Publication date |
|---|---|
| DE19701931C1 (de) | 1998-05-28 |
| DE59800846D1 (de) | 2001-07-19 |
| ATE202228T1 (de) | 2001-06-15 |
| IL130126A0 (en) | 2000-06-01 |
| EP0954802A1 (de) | 1999-11-10 |
| US6134510A (en) | 2000-10-17 |
| EP0954802B1 (de) | 2001-06-13 |
| JP2001508899A (ja) | 2001-07-03 |
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