WO1999021005A3 - Pharmaceutical grade st. john's wort - Google Patents

Pharmaceutical grade st. john's wort Download PDF

Info

Publication number
WO1999021005A3
WO1999021005A3 PCT/US1998/022504 US9822504W WO9921005A3 WO 1999021005 A3 WO1999021005 A3 WO 1999021005A3 US 9822504 W US9822504 W US 9822504W WO 9921005 A3 WO9921005 A3 WO 9921005A3
Authority
WO
WIPO (PCT)
Prior art keywords
wort
john
materials
pharmaceutical grade
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1998/022504
Other languages
French (fr)
Other versions
WO1999021005A2 (en
Inventor
Tasneem A Khwaja
Elliot P Friedman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PharmaPrint Inc
University of Southern California USC
Original Assignee
PharmaPrint Inc
University of Southern California USC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/956,602 external-priority patent/US6113907A/en
Application filed by PharmaPrint Inc, University of Southern California USC filed Critical PharmaPrint Inc
Priority to AU13631/99A priority Critical patent/AU1363199A/en
Priority to CA002306818A priority patent/CA2306818A1/en
Priority to EP98957355A priority patent/EP1094825A2/en
Publication of WO1999021005A2 publication Critical patent/WO1999021005A2/en
Anticipated expiration legal-status Critical
Publication of WO1999021005A3 publication Critical patent/WO1999021005A3/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/38Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/84Valerianaceae (Valerian family), e.g. valerian

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates generally to St. John's Wort materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. More particularly, the present invention relates to the use of compositional and activity fingerprints in the processing of St. John's Wort materials to produce drugs which qualify as pharmaceutical grade compositions which are suitable for use in clinical or veterinary settings to treat and/or ameliorate diseases, disorders or conditions.
PCT/US1998/022504 1997-10-23 1998-10-23 Pharmaceutical grade st. john's wort Ceased WO1999021005A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU13631/99A AU1363199A (en) 1997-10-23 1998-10-23 Pharmaceutical grade st. john's wort
CA002306818A CA2306818A1 (en) 1997-10-23 1998-10-23 Pharmaceutical grade st. john's wort
EP98957355A EP1094825A2 (en) 1997-10-23 1998-10-23 Pharmaceutical grade st. john's wort

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/956,602 US6113907A (en) 1997-04-15 1997-10-23 Pharmaceutical grade St. John's Wort
US08/956,602 1997-10-23
US15931398A 1998-09-23 1998-09-23
US09/159,313 1998-09-23

Publications (2)

Publication Number Publication Date
WO1999021005A2 WO1999021005A2 (en) 1999-04-29
WO1999021005A3 true WO1999021005A3 (en) 2001-02-22

Family

ID=26855832

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/022504 Ceased WO1999021005A2 (en) 1997-10-23 1998-10-23 Pharmaceutical grade st. john's wort

Country Status (4)

Country Link
EP (1) EP1094825A2 (en)
AU (1) AU1363199A (en)
CA (1) CA2306818A1 (en)
WO (1) WO1999021005A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100407399B1 (en) * 2000-08-22 2003-11-28 주식회사 뉴로넥스 Use of myricetin as an inhibitor for serotonin N-acetyltransferase
BR0204228A (en) * 2001-02-20 2004-06-22 Randy Ziegler Methods to improve the symptoms of a psychosis and schizophrenia and to screen test molecules, and, organic compound.
CN111175428B (en) * 2020-01-07 2022-09-09 江苏省中医院 The detection method of the fingerprint of Bushen Zhuyun Granules
CN112697899B (en) * 2020-12-07 2022-04-12 中国药科大学 Detection method of ginkgo flavonol glycosides
CN118169291B (en) * 2024-04-11 2024-08-13 南京柯菲平盛辉制药有限公司 Construction method and application of Naomaili granule fingerprint

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH680570A5 (en) * 1990-10-30 1992-09-30 Flint Ag Allergen-free St. Johns wort extract prodn. to prevent skin tumour - by macerating mechanically comminuted St. Johns wort and camomile with a plant oil e.g. wheat germ, thistle, sunflower seed, etc.
WO1997039355A1 (en) * 1996-04-15 1997-10-23 Pharmaprint, Inc. Pharmaceutical grade botanical drugs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH680570A5 (en) * 1990-10-30 1992-09-30 Flint Ag Allergen-free St. Johns wort extract prodn. to prevent skin tumour - by macerating mechanically comminuted St. Johns wort and camomile with a plant oil e.g. wheat germ, thistle, sunflower seed, etc.
WO1997039355A1 (en) * 1996-04-15 1997-10-23 Pharmaprint, Inc. Pharmaceutical grade botanical drugs

Also Published As

Publication number Publication date
CA2306818A1 (en) 1999-04-29
WO1999021005A2 (en) 1999-04-29
EP1094825A2 (en) 2001-05-02
AU1363199A (en) 1999-05-10

Similar Documents

Publication Publication Date Title
CA2392879A1 (en) A pyrrolidineacetamide derivative alone or in combination for treatment of cns disorders
IL152659A (en) Liquid pharmaceutical compositions comprising a pegylated human erythropoietin protein and a multiple charged inorganic anion, in a pharmaceutically acceptable buffer
WO2001041762A3 (en) Valdecoxib compositions
ZA975866B (en) Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases.
MA26536A1 (en) COMBINATION OF PHARMACEUTICAL COMPOSITIONS OF ATORVASTATIN AND ANTIHYPERTENSITIVE AGENTS, AND PROCESS FOR THEIR PREPARATION.
HUP0104867A3 (en) Heterocyclic compounds useful in the treatment of inflammatory diseases, process for their preparation, pharmaceutical compositions comprising thereof and their use
MA26420A1 (en) MIXED PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF OSTEOPOROSIS, AND METHOD FOR THEIR PREPARATION.
SI0751129T1 (en) Substituted dihydrodibenzo(b,f)azepines, method for their preparation, their use in the treatment of some central nervous system disorders, and pharmaceutical compositions containing them
WO1999048482A3 (en) Smilagenin and anzurogenin-d for the treatment of alzheimer's disease
AU8317498A (en) Fluoxetine pharmaceutical formulations
IL112664A0 (en) 4-amino derivatives of mycophenolic acid, their preparation and pharmaceutical compositions containing them
WO2001009118A3 (en) Dithiolthione compounds for the treatment of neurological disorders and for memory enhancement
AU3356500A (en) Use of aerosolized cyclosporine for prevention and treatment of pulmonary disease
IL112667A0 (en) 6-substituted derivatives of mycophenolic acid, their preparation and pharmaceutical compositions containing them
CA2436540A1 (en) Pharmaceutical compositions based on anticholinergics and corticosteroids
HUP0301167A3 (en) Sulfonyl-pyrrolidine derivatives useful for the treatment of neurological disorders, process for their preparation, pharmaceutical compositions containing them and their use
EP0797999A3 (en) Formulations of obesity protein
MY118526A (en) Method for improving the pharmacokinetics of tipranavir
AU2001266152A1 (en) Novel substituted nitrocatechols, their use in the treatment of some central andperipheral nervous system disorders and pharmaceutical compositions containing them
WO2001001974A3 (en) Naaladase inhibitors in anxiety and memory disorders
ZA98960B (en) Pharmaceutical composition for treatment of synaptic dysfunction and related disease disorders
AU3364499A (en) Method for delaying the onset of alzheimer's disease and for treating or delaying the onset of other amyloidosis-related diseases/disorders
WO1999020291A3 (en) Pharmaceutical grade ginkgo biloba
HUP0401325A3 (en) Isoxazolopyridinones useful in the treatment of parkinson's disease, process for their preparation and pharmaceutical compositions containing the compounds
CA2217513A1 (en) Pharmaceutical agents for the treatment of alzheimer's disease

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
ENP Entry into the national phase

Ref document number: 2306818

Country of ref document: CA

Ref country code: CA

Ref document number: 2306818

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 1998957355

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: KR

WWE Wipo information: entry into national phase

Ref document number: 13631/99

Country of ref document: AU

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWP Wipo information: published in national office

Ref document number: 1998957355

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1998957355

Country of ref document: EP