WO1999054461A3 - Menschliche nukleinsäuresequenzen aus endometriumtumorgewebe - Google Patents

Menschliche nukleinsäuresequenzen aus endometriumtumorgewebe Download PDF

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Publication number
WO1999054461A3
WO1999054461A3 PCT/DE1999/001174 DE9901174W WO9954461A3 WO 1999054461 A3 WO1999054461 A3 WO 1999054461A3 DE 9901174 W DE9901174 W DE 9901174W WO 9954461 A3 WO9954461 A3 WO 9954461A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid sequences
tumour tissue
human nucleic
endometrium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DE1999/001174
Other languages
English (en)
French (fr)
Other versions
WO1999054461A2 (de
Inventor
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
METAGEN GESELLSCHAFT fur GENOMFORSCHUNG MBH
Original Assignee
METAGEN GESELLSCHAFT fur GENOMFORSCHUNG MBH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by METAGEN GESELLSCHAFT fur GENOMFORSCHUNG MBH filed Critical METAGEN GESELLSCHAFT fur GENOMFORSCHUNG MBH
Priority to EP99923403A priority Critical patent/EP1071775A2/de
Priority to US09/673,395 priority patent/US6620923B1/en
Priority to JP2000544793A priority patent/JP2002532055A/ja
Publication of WO1999054461A2 publication Critical patent/WO1999054461A2/de
Publication of WO1999054461A3 publication Critical patent/WO1999054461A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Es werden menschliche Nukleinsäuresequenzen-mRNA, cDNA, genomische Sequenzen - aus Endometriumtumor, die für Genprodukte oder Teile davon kodieren, und deren Verwendung beschrieben. Es werden weiterhin die über die Sequenzen erhältlichen Polypeptide und deren Verwendung beschrieben.
PCT/DE1999/001174 1998-04-17 1999-04-15 Menschliche nukleinsäuresequenzen aus endometriumtumorgewebe Ceased WO1999054461A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP99923403A EP1071775A2 (de) 1998-04-17 1999-04-15 Menschliche nukleinsäuresequenzen aus endometriumtumorgewebe
US09/673,395 US6620923B1 (en) 1998-04-17 1999-04-15 Human nucleic acid sequences from endometrial tumor tissue
JP2000544793A JP2002532055A (ja) 1998-04-17 1999-04-15 子宮内膜腫瘍組織からのヒト核酸配列

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19817948A DE19817948A1 (de) 1998-04-17 1998-04-17 Menschliche Nukleinsäuresequenzen aus Endometrium-Tumor
DE19817948.0 1998-04-17

Publications (2)

Publication Number Publication Date
WO1999054461A2 WO1999054461A2 (de) 1999-10-28
WO1999054461A3 true WO1999054461A3 (de) 2000-07-06

Family

ID=7865426

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1999/001174 Ceased WO1999054461A2 (de) 1998-04-17 1999-04-15 Menschliche nukleinsäuresequenzen aus endometriumtumorgewebe

Country Status (5)

Country Link
US (1) US6620923B1 (de)
EP (1) EP1071775A2 (de)
JP (1) JP2002532055A (de)
DE (1) DE19817948A1 (de)
WO (1) WO1999054461A2 (de)

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US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20030003507A1 (en) 1999-06-02 2003-01-02 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US7014996B1 (en) 1998-10-02 2006-03-21 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating gynecologic cancers
CN1334873A (zh) * 1998-12-01 2002-02-06 伊东恭悟 新型肿瘤抗原蛋白art－1及其肿瘤抗原肽
WO2000043513A1 (en) * 1999-01-21 2000-07-27 Millennium Pharmaceuticals, Inc. 17723 receptor, a g-protein coupled receptor
MXPA01009688A (es) * 1999-03-26 2002-03-27 Smithkline Beecham Biolog Compuestos novedosos.
US6951738B2 (en) 1999-07-16 2005-10-04 Human Genome Sciences, Inc. Human tumor necrosis factor receptors TR13 and TR14
JP2003506042A (ja) 1999-08-03 2003-02-18 ミレニアム ファーマシューティカルズ インク． セクレチン様ファミリーの新規ｇｐｃｒ様分子１５５７１及びその使用
WO2001021815A1 (en) * 1999-09-23 2001-03-29 Rigel Pharmaceuticals, Inc. Checkpoint gene associated cell cycle proteins, compositions and methods of use
FR2800388A1 (fr) * 1999-10-29 2001-05-04 Pf Medicament Clonage, expression et caracterisation d'un gene exprime dans des cellules tumorales et implique dans la regulation de la reponse immune
ES2171104B1 (es) * 1999-11-29 2003-12-16 Univ Oviedo Procedimiento de identificacion de la metaloproteasa humana matrilisina-2.
FR2802945A1 (fr) * 1999-12-28 2001-06-29 Pf Medicament Nouvelle metalloprotease matricielle mmp-25 homologue de la matrilysine
AU6802801A (en) * 2000-03-01 2001-09-24 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU2001249317A1 (en) * 2000-03-21 2001-10-03 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian and endometrial cancer
JP2004500852A (ja) * 2000-05-19 2004-01-15 エフ．　ホフマン−ラ　ロシュ　アーゲー ヒト腫瘍細胞においてダウンレギュレートされる核酸の使用による、試料の殺腫瘍能を決定するためのプロセス
AU2001263342A1 (en) * 2000-05-19 2001-12-03 Millennium Pharmaceuticals, Inc. 32263, a putative human biotin transcarboxylase and uses thereof
WO2001098543A2 (en) * 2000-06-21 2001-12-27 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating breast cancer
AU2001280987A1 (en) * 2000-08-03 2002-02-18 Corixa Corporation Compositions and methods for the therapy and diagnosis of head and neck cancer
IL154663A0 (en) * 2000-09-01 2003-09-17 Epigenomics Ag Method for determining the degree of methylation of defined cytosines in genomic dna in the sequence context 5'-cpg-3'
WO2002070744A2 (en) * 2001-03-07 2002-09-12 Galapagos Genomics B.V. Adenoviral library assay for e2f regulatory genes and methods and compositions for screening compounds
US20030211039A1 (en) * 2001-05-29 2003-11-13 Macina Roberto A. Method of diagnosing, monitoring, staging, imaging and treating colon cancer
US7622260B2 (en) 2001-09-05 2009-11-24 The Brigham And Women's Hospital, Inc. Diagnostic and prognostic tests
JP2003284574A (ja) * 2001-10-03 2003-10-07 Pfizer Prod Inc 核酸分子、ポリペプチド、ならびにアルツハイマー病の診断および処置を含むそれらの使用
AU2004247069A1 (en) * 2003-06-02 2004-12-23 Alexion Pharmaceuticals, Inc. Cell surface protein associated with human chronic lymphocytic leukemia
EP1981984A2 (de) * 2005-12-31 2008-10-22 Genentech, Inc. Phosphorylierte cop1-moleküle und verwendungen davon
US8685660B2 (en) 2008-09-03 2014-04-01 The Johns Hopkins University Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma
JP2012511894A (ja) * 2008-09-04 2012-05-31 オックスフォード ビオトヘラペウトイクス エルティーディー． Ｐｔａ０７２タンパク質
US8871901B2 (en) * 2010-03-22 2014-10-28 Auburn University Phage constructs, sequences and antigenic compositions for immunocontraception of animals
EP4110467A4 (de) * 2020-03-31 2024-03-27 The Administrators of the Tulane Educational Fund Antivirale peptide mit breitem spektrum
WO2022172264A1 (en) * 2021-02-11 2022-08-18 Ramot At Tel Aviv University Ltd. Compositions and methods for treating a disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6174992B1 (en) * 1997-03-21 2001-01-16 Human Genome Sciences, Inc. Human endometrial specific steroid-binding factor I, II and III
WO1997034997A1 (en) * 1996-03-21 1997-09-25 Human Genome Sciences, Inc. Human endometrial specific steroid-binding factor i, ii and iii

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
A. KOUL ET AL.: "A somatic BRCA2 mutation in RER+ endometrial carcinomas that specifically deletes the amino-terminal transactivation domain", GENES, CHROMOSOMES & CANCER, vol. 24, no. 3, March 1999 (1999-03-01), pages 207 - 212, XP002127135 *
ADAMS M.D. ET AL.: "EST41316 Endometrial tumor Homo sapiens cDNA 5' end.", EMBL ACCESSION NO. AA336687, 18 April 1997 (1997-04-18), XP002127129 *
ADAMS M.D. ET AL.: "EST41427 Endometrial tumor Homo sapiens cDNA 5' end.", EMBL ACCESSION NO. AA336787, 18 April 1997 (1997-04-18), XP002127130 *
E. STRUNCK ET AL.: "Basement membrane regulates gene expression in HEC1B(L) Endometrial adenocarcinoma cells.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 221, no. 2, 1996, pages 346 - 350, XP002127131 *
M. SAKATA ET AL.: "Messenger RNA differential display reverse-transcriptase-polymerase-chain-reaction analysis of a progestogen-suppressive gene in a human endometrial-cancer cell line.", INTERNATIONAL JOURNAL OF CANCER, vol. 78, no. 1, 25 September 1998 (1998-09-25), pages 125 - 129, XP002127136 *
M.F. ARLT ET AL.: "Frequent deletion of chromosome 1p sequences in an aggressive histologic subtype of endometrial cancer.", HUMAN MOLECULAR GENETICS, vol. 5, no. 7, 1996, pages 1017 - 1021, XP002127133 *
MAHMOOD MANAVI, M.D. ET AL.: "Amplification and expression of the c-erbB-2 oncogene in Müllerian-derived Genital-tract tumors.", GYNECOLOGIC ONCOLOGY, vol. 71, no. 2, November 1998 (1998-11-01), pages 165 - 171, XP002127134 *
TO HOA THAI ET AL.: "Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers.", HUMAN MOLECULAR GENETICS, vol. 7, no. 2, 1998, pages 195 - 202, XP002127132 *

Also Published As

Publication number Publication date
WO1999054461A2 (de) 1999-10-28
US6620923B1 (en) 2003-09-16
EP1071775A2 (de) 2001-01-31
JP2002532055A (ja) 2002-10-02
DE19817948A1 (de) 1999-10-21

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