WO1999058676A3 - Semaphorin polypeptides - Google Patents

Semaphorin polypeptides Download PDF

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Publication number
WO1999058676A3
WO1999058676A3 PCT/US1999/009831 US9909831W WO9958676A3 WO 1999058676 A3 WO1999058676 A3 WO 1999058676A3 US 9909831 W US9909831 W US 9909831W WO 9958676 A3 WO9958676 A3 WO 9958676A3
Authority
WO
WIPO (PCT)
Prior art keywords
semaphorin
polypeptide
semaphorin polypeptides
polypeptides
semaphorin polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/009831
Other languages
French (fr)
Other versions
WO1999058676A2 (en
Inventor
Melanie K Spriggs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Priority to EP99920356A priority Critical patent/EP1076697B1/en
Priority to AU37874/99A priority patent/AU3787499A/en
Priority to DE69939587T priority patent/DE69939587D1/en
Publication of WO1999058676A2 publication Critical patent/WO1999058676A2/en
Publication of WO1999058676A3 publication Critical patent/WO1999058676A3/en
Priority to US09/689,012 priority patent/US6670135B1/en
Anticipated expiration legal-status Critical
Priority to US10/740,773 priority patent/US20040180825A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention is directed to semaphorin polypeptide as a purified and isolated protein, the DNA encoding the semaphorin polypeptide, host cells transfected with cDNAs encoding the polypeptide and methods for preparing the semaphorin polypeptide.
PCT/US1999/009831 1998-05-14 1999-05-05 Semaphorin polypeptides Ceased WO1999058676A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP99920356A EP1076697B1 (en) 1998-05-14 1999-05-05 Semaphorin polypeptides
AU37874/99A AU3787499A (en) 1998-05-14 1999-05-05 Semaphorin polypeptides
DE69939587T DE69939587D1 (en) 1998-05-14 1999-05-05 Semaphorin polypeptide
US09/689,012 US6670135B1 (en) 1998-05-14 2000-10-12 Semaphorin polypeptides
US10/740,773 US20040180825A1 (en) 1998-05-14 2003-12-19 Semaphorin polypeptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8549798P 1998-05-14 1998-05-14
US60/085,497 1998-05-14

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09/689,012 Continuation US6670135B1 (en) 1998-05-14 2000-10-12 Semaphorin polypeptides

Publications (2)

Publication Number Publication Date
WO1999058676A2 WO1999058676A2 (en) 1999-11-18
WO1999058676A3 true WO1999058676A3 (en) 2000-01-20

Family

ID=22192003

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/009831 Ceased WO1999058676A2 (en) 1998-05-14 1999-05-05 Semaphorin polypeptides

Country Status (7)

Country Link
US (2) US6670135B1 (en)
EP (1) EP1076697B1 (en)
AT (1) ATE408687T1 (en)
AU (1) AU3787499A (en)
DE (1) DE69939587D1 (en)
ES (1) ES2315011T3 (en)
WO (1) WO1999058676A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892047A3 (en) 1997-07-09 2000-03-08 Hoechst Marion Roussel Deutschland GmbH Human and murine semaphorin L
WO2001039793A2 (en) * 1999-11-30 2001-06-07 Smithkline Beecham P.L.C. Pharmaceutical compositions containing sema7a polypeptides
GB0522112D0 (en) * 2005-10-29 2005-12-07 Ge Healthcare Ltd Novel imaging agents for cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892047A2 (en) * 1997-07-09 1999-01-20 Hoechst Marion Roussel Deutschland GmbH Human and murine semaphorin L
WO1999045114A2 (en) * 1998-03-03 1999-09-10 Zymogenetics, Inc. Human semaphorin zsmf-7

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999021997A1 (en) * 1997-10-28 1999-05-06 Immunex Corporation Viral encoded semaphorin protein receptor dna and polypeptides
EP0933425A1 (en) 1998-01-30 1999-08-04 Smithkline Beecham Plc Semaphorin family polypeptides and polynucleotides
US6225285B1 (en) 1998-03-11 2001-05-01 Exelixis Pharmaceuticals, Inc. Semaphorin K1

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892047A2 (en) * 1997-07-09 1999-01-20 Hoechst Marion Roussel Deutschland GmbH Human and murine semaphorin L
WO1999045114A2 (en) * 1998-03-03 1999-09-10 Zymogenetics, Inc. Human semaphorin zsmf-7

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ENSSER A ET AL: "Alcephaline herpesvirus type 1 has a semaphorin-like gene", JOURNAL OF GENERAL VIROLOGY., vol. 76, 1995, SOCIETY FOR GENERAL MICROBIOLOGY, READING., GB, pages 1063 - 1067, XP002113888, ISSN: 0022-1317 *
LANGE C ET AL: "New eukaryotic semaphorins with close homology to semaphorins of viruses", GENOMICS, vol. 51, 1 August 1998 (1998-08-01), SAN DIEGO., US, pages 340 - 350, XP002113887, ISSN: 0888-7543 *
XU X ET AL: "Human semaphorin K1 is glycosylphosphatidylinositol-linked and defines a new subfamily of viral-related semaphorins", JOURNAL OF BIOLOGICAL CHEMISTRY., vol. 273, no. 35, 28 August 1998 (1998-08-28), AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD., US, pages 22428 - 22434, XP002113886, ISSN: 0021-9258 *
YAMADA A ET AL: "Molecular cloning of a glycosylphosphatidylinositol-anchored molecule CDw108", JOURNAL OF IMMUNOLOGY., vol. 162, 1 April 1999 (1999-04-01), THE WILLIAMS AND WILKINS CO. BALTIMORE., US, pages 4094 - 4100, XP002123609, ISSN: 0022-1767 *

Also Published As

Publication number Publication date
US6670135B1 (en) 2003-12-30
EP1076697A2 (en) 2001-02-21
EP1076697B1 (en) 2008-09-17
WO1999058676A2 (en) 1999-11-18
ATE408687T1 (en) 2008-10-15
ES2315011T3 (en) 2009-03-16
US20040180825A1 (en) 2004-09-16
DE69939587D1 (en) 2008-10-30
AU3787499A (en) 1999-11-29

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