WO1999061911A3 - Nanometer particles containing a reactive monolayer - Google Patents

Nanometer particles containing a reactive monolayer Download PDF

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Publication number
WO1999061911A3
WO1999061911A3 PCT/US1999/007823 US9907823W WO9961911A3 WO 1999061911 A3 WO1999061911 A3 WO 1999061911A3 US 9907823 W US9907823 W US 9907823W WO 9961911 A3 WO9961911 A3 WO 9961911A3
Authority
WO
WIPO (PCT)
Prior art keywords
monolayer
nanometer
core
sized particle
particles containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/007823
Other languages
French (fr)
Other versions
WO1999061911A2 (en
Inventor
Royce W Murray
Allen C Templeton
Michael J Hostetler
Jeremy J Pietron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of North Carolina at Chapel Hill
Original Assignee
University of North Carolina at Chapel Hill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of North Carolina at Chapel Hill filed Critical University of North Carolina at Chapel Hill
Priority to CA002329859A priority Critical patent/CA2329859A1/en
Priority to EP99953384A priority patent/EP1073902A2/en
Priority to AU60169/99A priority patent/AU6016999A/en
Publication of WO1999061911A2 publication Critical patent/WO1999061911A2/en
Publication of WO1999061911A3 publication Critical patent/WO1999061911A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0004—Preparation of sols
    • B01J13/0043—Preparation of sols containing elemental metal
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nanotechnology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Powder Metallurgy (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

A nanometer-sized particle comprises a core comprising at least one metal or metal alloy; and a monolayer chemically bonded to the core. The monolayer contains at least one reactive substituent which is coupled to a functional material such that the monolayer is chemically modified. A method of making a functionalized nanometer-sized particle comprises providing a nanometer-sized particle comprising a core which comprises at least one metal or metal alloy, and a monolayer adsorbed onto the core wherein the monolayer includes at least one reactive substituent; and coupling the nanometer-sized particle with a functional material such that the monolayer is chemically modified.
PCT/US1999/007823 1998-04-20 1999-04-09 Nanometer particles containing a reactive monolayer Ceased WO1999061911A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002329859A CA2329859A1 (en) 1998-04-20 1999-04-09 Nanometer particles containing a reactive monolayer
EP99953384A EP1073902A2 (en) 1998-04-20 1999-04-09 Nanometer particles containing a reactive monolayer
AU60169/99A AU6016999A (en) 1998-04-20 1999-04-09 Nanometer sized particles containing a reactive monolayer adsorbed thereon and methods of making the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6286398A 1998-04-20 1998-04-20
US09/062,863 1998-04-20

Publications (2)

Publication Number Publication Date
WO1999061911A2 WO1999061911A2 (en) 1999-12-02
WO1999061911A3 true WO1999061911A3 (en) 2000-03-09

Family

ID=22045338

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/007823 Ceased WO1999061911A2 (en) 1998-04-20 1999-04-09 Nanometer particles containing a reactive monolayer

Country Status (4)

Country Link
EP (1) EP1073902A2 (en)
AU (1) AU6016999A (en)
CA (1) CA2329859A1 (en)
WO (1) WO1999061911A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7533361B2 (en) 2005-01-14 2009-05-12 Cabot Corporation System and process for manufacturing custom electronics by combining traditional electronics with printable electronics
US7575621B2 (en) 2005-01-14 2009-08-18 Cabot Corporation Separation of metal nanoparticles

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001513697A (en) 1997-02-24 2001-09-04 スーペリア マイクロパウダーズ リミテッド ライアビリティ カンパニー Aerosol method and apparatus, particle product, and electronic device manufactured from the particle product
GB0025414D0 (en) * 2000-10-16 2000-11-29 Consejo Superior Investigacion Nanoparticles
US6653653B2 (en) 2001-07-13 2003-11-25 Quantum Logic Devices, Inc. Single-electron transistors and fabrication methods in which a projecting feature defines spacing between electrodes
US6483125B1 (en) 2001-07-13 2002-11-19 North Carolina State University Single electron transistors in which the thickness of an insulating layer defines spacing between electrodes
GB0126236D0 (en) 2001-11-01 2002-01-02 Univ East Anglia Photosensitiser functionalised nanoparticles
US6673717B1 (en) 2002-06-26 2004-01-06 Quantum Logic Devices, Inc. Methods for fabricating nanopores for single-electron devices
GB0313259D0 (en) 2003-06-09 2003-07-16 Consejo Superior Investigacion Magnetic nanoparticles
FR2859117B1 (en) * 2003-08-27 2006-02-03 Commissariat Energie Atomique USE OF NANOPARTICLES WITH A METAL HEART AND DOUBLE ORGANIC COATING AS CATALYSTS AND NANOPARTICLES USEFUL AS CATALYSTS
US9079765B2 (en) * 2004-10-01 2015-07-14 Midatech Ltd. Nanoparticles comprising antigens and adjuvants, and immunogenic structures
US7824466B2 (en) 2005-01-14 2010-11-02 Cabot Corporation Production of metal nanoparticles
CN1305977C (en) * 2005-03-04 2007-03-21 北京化工大学 Method for modifying the surface of nano inorganic particles by transfer method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0426300A1 (en) * 1989-09-29 1991-05-08 Ortho Diagnostic Systems Inc. Method of producing a reagent containing a narrow distribution of colloidal particles of a selected size and the use thereof
EP0428412A2 (en) * 1989-11-16 1991-05-22 Ortho Diagnostic Systems Inc. Method of producing a metal sol reagent containing colloidal metal particles of a preselected size

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0426300A1 (en) * 1989-09-29 1991-05-08 Ortho Diagnostic Systems Inc. Method of producing a reagent containing a narrow distribution of colloidal particles of a selected size and the use thereof
EP0428412A2 (en) * 1989-11-16 1991-05-22 Ortho Diagnostic Systems Inc. Method of producing a metal sol reagent containing colloidal metal particles of a preselected size

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7533361B2 (en) 2005-01-14 2009-05-12 Cabot Corporation System and process for manufacturing custom electronics by combining traditional electronics with printable electronics
US7575621B2 (en) 2005-01-14 2009-08-18 Cabot Corporation Separation of metal nanoparticles

Also Published As

Publication number Publication date
EP1073902A2 (en) 2001-02-07
AU6016999A (en) 1999-12-13
WO1999061911A2 (en) 1999-12-02
CA2329859A1 (en) 1999-12-02

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