WO1999066974A3 - Vorrichtung zum leersaugen pulverenthaltender kavitäten - Google Patents

Vorrichtung zum leersaugen pulverenthaltender kavitäten Download PDF

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Publication number
WO1999066974A3
WO1999066974A3 PCT/EP1999/004304 EP9904304W WO9966974A3 WO 1999066974 A3 WO1999066974 A3 WO 1999066974A3 EP 9904304 W EP9904304 W EP 9904304W WO 9966974 A3 WO9966974 A3 WO 9966974A3
Authority
WO
WIPO (PCT)
Prior art keywords
cavities
suction
relation
cavity
emptying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1999/004304
Other languages
English (en)
French (fr)
Other versions
WO1999066974A2 (de
Inventor
Schuckmann Alfred Von
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19855851A external-priority patent/DE19855851A1/de
Priority to BR9911429-1A priority Critical patent/BR9911429A/pt
Priority to AT99932708T priority patent/ATE277658T1/de
Priority to NZ508618A priority patent/NZ508618A/en
Priority to EP99932708A priority patent/EP1089783B1/de
Priority to AU48999/99A priority patent/AU753094B2/en
Priority to IL14031299A priority patent/IL140312A0/xx
Application filed by Individual filed Critical Individual
Priority to SK1972-2000A priority patent/SK286302B6/sk
Priority to HU0102534A priority patent/HU224243B1/hu
Priority to JP2000555659A priority patent/JP4225692B2/ja
Priority to DK99932708T priority patent/DK1089783T3/da
Priority to CA002334950A priority patent/CA2334950C/en
Priority to EEP200000769A priority patent/EE04455B1/xx
Priority to DE59910669T priority patent/DE59910669D1/de
Priority to HK01108320.3A priority patent/HK1037549B/xx
Priority to PL99345363A priority patent/PL345363A1/xx
Priority to US09/719,786 priority patent/US6722363B1/en
Publication of WO1999066974A2 publication Critical patent/WO1999066974A2/de
Publication of WO1999066974A3 publication Critical patent/WO1999066974A3/de
Priority to IL140312A priority patent/IL140312A/en
Priority to IS5780A priority patent/IS2660B/is
Priority to NO20006557A priority patent/NO20006557L/no
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0023—Mouthpieces therefor retractable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • Catching Or Destruction (AREA)
  • Basic Packing Technique (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Crushing And Pulverization Processes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Cleaning In General (AREA)
  • Dental Preparations (AREA)
  • Cosmetics (AREA)

Abstract

Die Erfindung betrifft eine Vorrichtung (V) zum Entleeren pulverenthaltender und mittels Deckfolie (9) verschlossener Kavitäten (1) mittels eines von Hand setzbaren Saugrohres (11), dessen vorderes Ende relativ zur Kavität (1) positioniert und geführt die Deckfolie (9) durchstößt unter Belassung eines freien Querschnitts zum Einströmen von Luft in die Kavität (1), und schlägt zur Erzielung einer herstellungsgünstigen, handhabungssicheren Lösung vor, daß das vordere Ende des Saugrohres (11) benachbart und axial überstehend zu dort vorgesehenen Schneidflanken (12) Fortsätze (22/82) besitzt, die sich in den Kavitäten (1) benachbarten Schlitzen (19 und/oder 83, 55 bzw. 25) eines Trägers (T) formschlüssig/drehfest führen, in welchem Träger (T) die Kavitäten (1) als Blisterpackungen (2) einsetzbar sind.
PCT/EP1999/004304 1998-06-22 1999-06-22 Vorrichtung zum leersaugen pulverenthaltender kavitäten Ceased WO1999066974A2 (de)

Priority Applications (19)

Application Number Priority Date Filing Date Title
EEP200000769A EE04455B1 (et) 1998-06-22 1999-06-22 Seade pulbrit sisaldavate õõnsuste tühjendamiseks
DK99932708T DK1089783T3 (da) 1999-06-22 1999-06-22 Fremgangsmåde til tomsugning af kaviteter, der indeholder pulver
NZ508618A NZ508618A (en) 1998-06-22 1999-06-22 Device for emptying cavities containing powder by means of suction
EP99932708A EP1089783B1 (de) 1998-06-22 1999-06-22 Vorrichtung zum leersaugen pulverenthaltender kavitäten
AU48999/99A AU753094B2 (en) 1998-06-22 1999-06-22 Device for emptying cavities containing powder by means of suction
IL14031299A IL140312A0 (en) 1998-06-22 1999-06-22 Device for emptying cavities containing powder by means of suction
AT99932708T ATE277658T1 (de) 1998-06-22 1999-06-22 Vorrichtung zum leersaugen pulverenthaltender kavitäten
SK1972-2000A SK286302B6 (en) 1998-06-22 1999-06-22 Device for emptying cavities containing powder by means of suction
HU0102534A HU224243B1 (hu) 1998-06-22 1999-06-22 Készülék port tartalmazó, buborékcsomagolást képező fedőfóliával lezárt mélyedések ürítéséhez, szívás alkalmazásával
JP2000555659A JP4225692B2 (ja) 1998-06-22 1999-06-22 粉末含有キャビティを吸入により空にするための装置
CA002334950A CA2334950C (en) 1998-06-22 1999-06-22 Device for emptying powder-containing cavities by suction
BR9911429-1A BR9911429A (pt) 1998-06-22 1999-06-22 Dispositivo para esvaziar cavidades contendo pó
US09/719,786 US6722363B1 (en) 1998-06-22 1999-06-22 Device for emptying cavities containing powder by means of suction
DE59910669T DE59910669D1 (de) 1998-06-22 1999-06-22 Vorrichtung zum leersaugen pulverenthaltender kavitäten
HK01108320.3A HK1037549B (en) 1998-06-22 1999-06-22 Device for emptying cavities containing powder by means of suction
PL99345363A PL345363A1 (en) 1998-06-22 1999-06-22 Device for emptying cavities containing powder by means of suction
IL140312A IL140312A (en) 1998-06-22 2000-12-14 Socket emptying device containing powder by pumping
IS5780A IS2660B (is) 1998-06-22 2000-12-20 Tæki til að tæma holur er innihalda duft með sogi
NO20006557A NO20006557L (no) 1998-06-22 2000-12-21 Innretning for tomsuging av kaviteter som inneholder pulver

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE19827731 1998-06-22
DE19827731.8 1998-06-22
DE19830713 1998-07-09
DE19830713.6 1998-07-09
DE19839516.7 1998-08-29
DE19839516 1998-08-29
DE19855851A DE19855851A1 (de) 1998-06-22 1998-12-04 Vorrichtung zum Leersaugen pulverenthaltender Kavitäten
DE19855851.1 1998-12-04

Publications (2)

Publication Number Publication Date
WO1999066974A2 WO1999066974A2 (de) 1999-12-29
WO1999066974A3 true WO1999066974A3 (de) 2000-05-04

Family

ID=27438821

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/004304 Ceased WO1999066974A2 (de) 1998-06-22 1999-06-22 Vorrichtung zum leersaugen pulverenthaltender kavitäten

Country Status (22)

Country Link
US (1) US6722363B1 (de)
EP (1) EP1089783B1 (de)
JP (1) JP4225692B2 (de)
CN (1) CN100371037C (de)
AT (1) ATE277658T1 (de)
AU (1) AU753094B2 (de)
BR (1) BR9911429A (de)
CA (1) CA2334950C (de)
CZ (1) CZ300314B6 (de)
EE (1) EE04455B1 (de)
ES (1) ES2228070T3 (de)
HU (1) HU224243B1 (de)
ID (1) ID28161A (de)
IL (1) IL140312A0 (de)
IS (1) IS2660B (de)
NO (1) NO20006557L (de)
NZ (1) NZ508618A (de)
PL (1) PL345363A1 (de)
PT (1) PT1089783E (de)
SK (1) SK286302B6 (de)
TR (1) TR200003856T2 (de)
WO (1) WO1999066974A2 (de)

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US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AU1068401A (en) * 1999-10-12 2001-04-23 Shl Medical Ab Inhaler
US6923175B2 (en) * 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
GR1004350B (el) * 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
DE10300032B3 (de) * 2003-01-03 2004-05-27 E. Braun Gmbh Pulverinhalator
GB2407042B (en) * 2003-10-17 2007-10-24 Vectura Ltd Inhaler
SE528190C2 (sv) * 2004-06-07 2006-09-19 Mederio Ag Inhalator
JP2008501473A (ja) * 2004-06-07 2008-01-24 メデリオ アーゲー 吸入可能な薬剤のドーズ品質の保証
FR2872798B1 (fr) * 2004-07-09 2007-10-05 Valois Sas Ensemble de blisters pour dispositif d'inhalation
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
GB0427028D0 (en) * 2004-12-09 2005-01-12 Cambridge Consultants Dry powder inhalers
CN101171182A (zh) * 2005-05-02 2008-04-30 阿斯利康(瑞典)有限公司 用于开启凹部的装置和方法、医用密封包及分配设备
EP1901793A1 (de) * 2005-07-13 2008-03-26 Cipla Ltd. Inhalator
MX373000B (es) 2005-09-14 2020-05-21 Mannkind Corp Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas.
EP1986679B1 (de) 2006-02-22 2017-10-25 MannKind Corporation Verfahren zur verbesserung der pharmazeutischen eigenschaften von mikropartikeln mit diketopiperazin und einem wirkstoff
GB0621957D0 (en) * 2006-11-03 2006-12-13 Vectura Group Plc Inhaler devices and bespoke pharmaceutical compositions
EP1992374A1 (de) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung
GB0713876D0 (en) * 2007-07-18 2007-08-29 3M Innovative Properties Co Manufacture of components for medicinal dispensers
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN101827626B (zh) 2008-06-13 2015-03-18 曼金德公司 干粉吸入器和用于药物输送的系统
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
WO2010036788A2 (en) * 2008-09-24 2010-04-01 The General Hospital Corporation Method and apparatus for grafting of skin tissue
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2210638B1 (de) * 2009-01-26 2013-03-27 Boehringer Ingelheim International GmbH Inhalator
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
KR102584844B1 (ko) 2009-06-12 2023-10-04 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CN102985125A (zh) 2010-06-21 2013-03-20 曼金德公司 干粉药物输送系统和方法
SG194034A1 (en) 2011-04-01 2013-11-29 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
MX2014004983A (es) 2011-10-24 2014-09-22 Mannkid Corp Metodos y composiciones para tratar dolor.
DE102012104850A1 (de) * 2012-04-05 2013-10-10 Alfred Von Schuckmann Vorrichtung zur portionierten Ausgabe von Medikamenten
KR102264177B1 (ko) 2012-07-12 2021-06-11 맨카인드 코포레이션 건조 분말 약물 전달 시스템 및 방법
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
EP3587404B1 (de) 2013-03-15 2022-07-13 MannKind Corporation Mikrokristalline diketopiperazinzusammensetzungen, verfahren zur herstellung und deren verwendung
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EP3030294B1 (de) 2013-08-05 2020-10-07 MannKind Corporation Insufflationsvorrichtung
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
CA2953624C (en) * 2014-07-08 2019-09-24 Medipense Inc. Pill dispenser with cylindrical package holder for array-type packages
EP3166866B1 (de) 2014-07-08 2019-04-03 Medipense Inc. Mechanismus zur ausgabe von pillen aus einer verpackungsanordnung
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
ES2701202T3 (es) * 2014-11-26 2019-02-21 Vectura Delivery Devices Ltd Dispositivo de apertura de envases tipo blíster para inhalador de polvo seco
DE102016119789A1 (de) * 2016-07-04 2018-01-04 Alfred Von Schuckmann Vorrichtung zur Ausgabe einer durch Luft austragbaren Substanz
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EP4204048B1 (de) * 2020-08-25 2024-10-09 Vectura Delivery Devices Limited Einzeldosistrockenpulverinhalator
TWI796680B (zh) * 2021-04-29 2023-03-21 宏洋精密工業股份有限公司 塑膠部品封包方法及其裝置

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2549303A (en) * 1949-04-20 1951-04-17 Bristol Lab Inc Inhaler for crystalline pencilllin or the like
EP0129985A1 (de) * 1983-05-24 1985-01-02 Glaxo Group Limited Inhaliervorrichtung
EP0467172A1 (de) * 1990-07-16 1992-01-22 Promo Pack Sa Inhalationsvorrichtung zur mehrfachen Ausgabe von Einzeldosen pulverförmiger Arzneimittel
US5415162A (en) * 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device
DE19619536A1 (de) * 1996-04-25 1997-10-30 Alfred Von Schuckmann Inhalier-Vorrichtung

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DE4027391A1 (de) 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
DE4239402A1 (de) 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
US5343672A (en) 1992-12-01 1994-09-06 Scherer Ltd R P Method for manufacturing freeze dried dosages in a multilaminate blister pack
JP3320261B2 (ja) * 1995-06-01 2002-09-03 株式会社ユニシアジェックス 吸入式投薬器
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
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Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2549303A (en) * 1949-04-20 1951-04-17 Bristol Lab Inc Inhaler for crystalline pencilllin or the like
EP0129985A1 (de) * 1983-05-24 1985-01-02 Glaxo Group Limited Inhaliervorrichtung
EP0467172A1 (de) * 1990-07-16 1992-01-22 Promo Pack Sa Inhalationsvorrichtung zur mehrfachen Ausgabe von Einzeldosen pulverförmiger Arzneimittel
US5415162A (en) * 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device
DE19619536A1 (de) * 1996-04-25 1997-10-30 Alfred Von Schuckmann Inhalier-Vorrichtung

Also Published As

Publication number Publication date
CA2334950A1 (en) 1999-12-29
SK286302B6 (en) 2008-07-07
HUP0102534A2 (hu) 2001-11-28
TR200003856T2 (tr) 2001-06-21
PL345363A1 (en) 2001-12-17
EE200000769A (et) 2002-06-17
IS5780A (is) 2000-12-20
CN100371037C (zh) 2008-02-27
US6722363B1 (en) 2004-04-20
BR9911429A (pt) 2001-03-20
CA2334950C (en) 2007-12-04
NZ508618A (en) 2002-05-31
NO20006557D0 (no) 2000-12-21
CZ300314B6 (cs) 2009-04-15
IS2660B (is) 2010-08-15
EP1089783A2 (de) 2001-04-11
JP4225692B2 (ja) 2009-02-18
EP1089783B1 (de) 2004-09-29
EE04455B1 (et) 2005-04-15
PT1089783E (pt) 2005-01-31
NO20006557L (no) 2000-12-21
ID28161A (id) 2001-05-10
ES2228070T3 (es) 2005-04-01
IL140312A0 (en) 2002-02-10
WO1999066974A2 (de) 1999-12-29
JP2002518139A (ja) 2002-06-25
AU4899999A (en) 2000-01-10
CN1306447A (zh) 2001-08-01
CZ20004768A3 (en) 2001-06-13
HUP0102534A3 (en) 2001-12-28
ATE277658T1 (de) 2004-10-15
AU753094B2 (en) 2002-10-10
HU224243B1 (hu) 2005-06-28
SK19722000A3 (sk) 2001-07-10

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