WO2000025171A3 - Anordnung zur optischen abtastung eines objekts - Google Patents

Anordnung zur optischen abtastung eines objekts Download PDF

Info

Publication number
WO2000025171A3
WO2000025171A3 PCT/DE1999/003400 DE9903400W WO0025171A3 WO 2000025171 A3 WO2000025171 A3 WO 2000025171A3 DE 9903400 W DE9903400 W DE 9903400W WO 0025171 A3 WO0025171 A3 WO 0025171A3
Authority
WO
WIPO (PCT)
Prior art keywords
arrangement
scanning
optically scanning
mirror
scan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DE1999/003400
Other languages
English (en)
French (fr)
Other versions
WO2000025171A2 (de
Inventor
Johann Engelhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leica Microsystems CMS GmbH
Original Assignee
Leica Microsystems Heidelberg GmbH
Leica Microsystems CMS GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19950225A external-priority patent/DE19950225A1/de
Application filed by Leica Microsystems Heidelberg GmbH, Leica Microsystems CMS GmbH filed Critical Leica Microsystems Heidelberg GmbH
Priority to DE59914912T priority Critical patent/DE59914912D1/de
Priority to EP99960812A priority patent/EP1049952B1/de
Priority to JP2000578692A priority patent/JP2003524194A/ja
Publication of WO2000025171A2 publication Critical patent/WO2000025171A2/de
Publication of WO2000025171A3 publication Critical patent/WO2000025171A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/0076Optical details of the image generation arrangements using fluorescence or luminescence
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036Scanning details, e.g. scanning stages
    • G02B21/0048Scanning details, e.g. scanning stages scanning mirrors, e.g. rotating or galvanomirrors, MEMS mirrors
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/006Optical details of the image generation focusing arrangements; selection of the plane to be imaged
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/0064Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B26/00Optical devices or arrangements for the control of light using movable or deformable optical elements
    • G02B26/08Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
    • G02B26/10Scanning systems
    • G02B26/101Scanning systems with both horizontal and vertical deflecting means, e.g. raster or XY scanners

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microscoopes, Condenser (AREA)
  • Optical Elements Other Than Lenses (AREA)
  • Mechanical Optical Scanning Systems (AREA)

Abstract

Eine Anordnung zur optischen Abtastung eines Objekts, insbesondere in der vorzugsweise konfokalen Laserscan-Mikroskopie, wobei im Beleuchtungs-/Detektionsstrahlengang (1, 2) eine Linse oder ein Objektiv (3) und mindestens ein Scanspiegel (4) angeordnet sind, ist zur Abtastung von die Objektfeldgröße der Mikroskopoptik überschreitende Objektfelder mit einer hinreichend schnellen Datenaufnahme und unter Verwendung einfacher optischer Komponenten dadurch gekennzeichnet, dass der Spiegel (4) mit einer zur Abtastfläche des Objekts zumindest weitgehend orthogonalen Drehachse (5) dreht bzw. schwenkt.
PCT/DE1999/003400 1998-10-24 1999-10-25 Anordnung zur optischen abtastung eines objekts Ceased WO2000025171A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE59914912T DE59914912D1 (de) 1998-10-24 1999-10-25 Anordnung zur optischen abtastung eines objekts
EP99960812A EP1049952B1 (de) 1998-10-24 1999-10-25 Anordnung zur optischen abtastung eines objekts
JP2000578692A JP2003524194A (ja) 1998-10-24 1999-10-25 対象物を光学的に走査するための装置

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19849143 1998-10-24
DE19849143.3 1998-10-24
DE19950225A DE19950225A1 (de) 1998-10-24 1999-10-19 Anordnung zur optischen Abtastung eines Objekts
DE19950225.0 1999-10-19

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US09582177 A-371-Of-International 2000-06-22
US10/201,225 Continuation US20030002148A1 (en) 1998-10-24 2002-07-22 Arrangement for optically scanning an object

Publications (2)

Publication Number Publication Date
WO2000025171A2 WO2000025171A2 (de) 2000-05-04
WO2000025171A3 true WO2000025171A3 (de) 2000-08-31

Family

ID=26049740

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1999/003400 Ceased WO2000025171A2 (de) 1998-10-24 1999-10-25 Anordnung zur optischen abtastung eines objekts

Country Status (3)

Country Link
EP (1) EP1049952B1 (de)
JP (1) JP2003524194A (de)
WO (1) WO2000025171A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011054914A1 (de) * 2011-10-28 2013-05-02 Leica Microsystems Cms Gmbh Verfahren und Anordnung zur Beleuchtung einer Probe
JP6980370B2 (ja) 2016-08-29 2021-12-15 オリンパス株式会社 顕微鏡システム
DE102019113975B4 (de) * 2019-05-24 2023-10-19 Abberior Instruments Gmbh Verfahren und Vorrichtung zum Überwachen des Fokuszustands eines Mikroskops sowie Mikroskop

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5785176A (en) * 1980-11-18 1982-05-27 Nippon Electric Ind Co Ltd Optical reader
JPS5986024A (ja) * 1982-11-08 1984-05-18 Mitsubishi Electric Corp ホログラム・スキヤナ
US5144477A (en) * 1988-04-11 1992-09-01 Medical Research Council Method of operating a scanning confocal imaging system
US5532873A (en) * 1993-09-08 1996-07-02 Dixon; Arthur E. Scanning beam laser microscope with wide range of magnification

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5785176A (en) * 1980-11-18 1982-05-27 Nippon Electric Ind Co Ltd Optical reader
JPS5986024A (ja) * 1982-11-08 1984-05-18 Mitsubishi Electric Corp ホログラム・スキヤナ
US5144477A (en) * 1988-04-11 1992-09-01 Medical Research Council Method of operating a scanning confocal imaging system
US5532873A (en) * 1993-09-08 1996-07-02 Dixon; Arthur E. Scanning beam laser microscope with wide range of magnification

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KENSINGTON LABS 8500 SERIES PRECISION STAGE, XP002132641, Retrieved from the Internet <URL:http://www.kensingtonlabs.com/products/8500stag> [retrieved on 20000309] *
PATENT ABSTRACTS OF JAPAN vol. 006, no. 168 (P - 139) 2 September 1982 (1982-09-02) *
PATENT ABSTRACTS OF JAPAN vol. 008, no. 202 (P - 300) 14 September 1984 (1984-09-14) *

Also Published As

Publication number Publication date
EP1049952A2 (de) 2000-11-08
JP2003524194A (ja) 2003-08-12
EP1049952B1 (de) 2008-11-26
WO2000025171A2 (de) 2000-05-04

Similar Documents

Publication Publication Date Title
EP0782027A3 (de) Konfokales Rastermikroskop
CA2663597C (en) Improvements in and relating to scanning confocal microscopy
CA2079882A1 (en) Confocal microscope
US6172789B1 (en) Light scanning device and confocal optical device using the same
AU3105199A (en) Wide field of view and high speed scanning microscopy
Bahlmann et al. 4Pi-confocal microscopy of live cells
EP0406413A4 (en) Scanning type tunnel microscope
WO1998028655A3 (en) Light modulated confocal optical instruments and method
WO1998028640A3 (de) Optische anordnung zum scannen eines strahls in zwei im wesentlichen senkrecht zueinander liegenden achsen
CA2290575A1 (en) High resolution confocal microscope
GB9016632D0 (en) Confocal imaging system for microscopy
Kam et al. Design and construction of an optimal illumination system for quantitative wide‐field multi‐dimensional microscopy
DE3785435D1 (de) Scanner zur optischen abtastung von objekten, insbesondere aufzeichnungsplatten.
WO2003102663A3 (en) Epi-illumination system for an array microscope
WO2000025171A3 (de) Anordnung zur optischen abtastung eines objekts
CA2031824A1 (en) Symbol reader
ATE127594T1 (de) Optisches phasenmessabtastmikroskop.
ES2111869T3 (es) Disposicion de fuente de alumbrado de fibra optica y con haz luminoso orientable.
WO2002084376A1 (en) Optical scanning device, image reading device provided with this, image forming device, and photographing device
DE59712409D1 (de) Konfokales mikroskop zur optischen erfassung eines beobachtungsvolumens
Gu et al. Experimental investigation of fibre-optical confocal scanning microscopy: including a comparison with pinhole detection
US5926311A (en) Illumination/viewing system for features in transparent materials
Aziz et al. Confocal microscopy via a fiber optic imaging bundle
Schmidt Confocal microscopy
JPH09145721A (ja) 光学顕微鏡一体型走査型プローブ顕微鏡

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

WWE Wipo information: entry into national phase

Ref document number: 1999960812

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 09582177

Country of ref document: US

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

WWP Wipo information: published in national office

Ref document number: 1999960812

Country of ref document: EP