WO2000032601A3 - Process for preparing cross-bridged tetraaza macrocycles - Google Patents

Process for preparing cross-bridged tetraaza macrocycles Download PDF

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Publication number
WO2000032601A3
WO2000032601A3 PCT/US1999/027316 US9927316W WO0032601A3 WO 2000032601 A3 WO2000032601 A3 WO 2000032601A3 US 9927316 W US9927316 W US 9927316W WO 0032601 A3 WO0032601 A3 WO 0032601A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparing cross
bridged tetraaza
hydrogen
independently
bridged
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/027316
Other languages
French (fr)
Other versions
WO2000032601A2 (en
Inventor
George Douglas Ii Hiler
Christopher Mark Perkins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22332328&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2000032601(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Priority to EP99963923A priority Critical patent/EP1135392A2/en
Priority to AU20261/00A priority patent/AU2026100A/en
Priority to JP2000585243A priority patent/JP2002531457A/en
Priority to CA002348893A priority patent/CA2348893A1/en
Publication of WO2000032601A2 publication Critical patent/WO2000032601A2/en
Publication of WO2000032601A3 publication Critical patent/WO2000032601A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/18—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms
    • B01J31/1805—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms the ligands containing nitrogen
    • B01J31/181—Cyclic ligands, including e.g. non-condensed polycyclic ligands, comprising at least one complexing nitrogen atom as ring member, e.g. pyridine
    • B01J31/1815—Cyclic ligands, including e.g. non-condensed polycyclic ligands, comprising at least one complexing nitrogen atom as ring member, e.g. pyridine with more than one complexing nitrogen atom, e.g. bipyridyl, 2-aminopyridine
    • B01J31/182—Cyclic ligands, including e.g. non-condensed polycyclic ligands, comprising at least one complexing nitrogen atom as ring member, e.g. pyridine with more than one complexing nitrogen atom, e.g. bipyridyl, 2-aminopyridine comprising aliphatic or saturated rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/70—Complexes comprising metals of Group VII (VIIB) as the central metal
    • B01J2531/72—Manganese
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/90—Catalytic systems characterized by the solvent or solvent system used
    • B01J2531/96—Water

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

The present invention relates to a process for preparing a cross-bridged tetraaza macrocyclic ligand having formula (I) wherein each R is independently C1-C8 linear or branched alkyl, -(CH2)xCO2M, and mixtures thereof; provided both of the R units are not methyl; M is hydrogen or a salt forming cation; x is from 1 to 6; each index n is independently from 0 to 3; by contacting a di-quaternary cis tetracycle precursor with hydrogen in the presence of a palladium catalyst in an aqueous solution having a pH of at least about 10 at a temperature of about 40 °C to about 100 °C.
PCT/US1999/027316 1998-11-30 1999-11-18 Process for preparing cross-bridged tetraaza macrocycles Ceased WO2000032601A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99963923A EP1135392A2 (en) 1998-11-30 1999-11-18 Process for preparing cross-bridged tetraaza macrocycles
AU20261/00A AU2026100A (en) 1998-11-30 1999-11-18 Process for preparing cross-bridged tetraaza macrocycles
JP2000585243A JP2002531457A (en) 1998-11-30 1999-11-18 Method for producing cross-linked tetraaza macrocycles
CA002348893A CA2348893A1 (en) 1998-11-30 1999-11-18 Process for preparing cross-bridged tetraaza macrocycles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11030998P 1998-11-30 1998-11-30
US60/110,309 1998-11-30

Publications (2)

Publication Number Publication Date
WO2000032601A2 WO2000032601A2 (en) 2000-06-08
WO2000032601A3 true WO2000032601A3 (en) 2000-10-05

Family

ID=22332328

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/027316 Ceased WO2000032601A2 (en) 1998-11-30 1999-11-18 Process for preparing cross-bridged tetraaza macrocycles

Country Status (5)

Country Link
EP (1) EP1135392A2 (en)
JP (1) JP2002531457A (en)
AU (1) AU2026100A (en)
CA (1) CA2348893A1 (en)
WO (1) WO2000032601A2 (en)

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