WO2000052151A3 - Human secretory proteins - Google Patents

Human secretory proteins Download PDF

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Publication number
WO2000052151A3
WO2000052151A3 PCT/US2000/005621 US0005621W WO0052151A3 WO 2000052151 A3 WO2000052151 A3 WO 2000052151A3 US 0005621 W US0005621 W US 0005621W WO 0052151 A3 WO0052151 A3 WO 0052151A3
Authority
WO
WIPO (PCT)
Prior art keywords
secretory proteins
human secretory
hsecp
provides
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/005621
Other languages
French (fr)
Other versions
WO2000052151A2 (en
Inventor
Y Tom Tang
Preeti Lal
Mariah R Baughn
Henry Yue
Janice Au-Young
Dyung Aina M Lu
Yalda Azimzai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharmaceuticals Inc filed Critical Incyte Pharmaceuticals Inc
Priority to AU33939/00A priority Critical patent/AU3393900A/en
Priority to JP2000602763A priority patent/JP2002537805A/en
Priority to CA002363684A priority patent/CA2363684A1/en
Priority to EP00912168A priority patent/EP1165766A2/en
Publication of WO2000052151A2 publication Critical patent/WO2000052151A2/en
Publication of WO2000052151A3 publication Critical patent/WO2000052151A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides human secretory proteins (HSECP) and polynucleotides which identify and encode HSECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSECP.
PCT/US2000/005621 1999-03-05 2000-03-03 Human secretory proteins Ceased WO2000052151A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU33939/00A AU3393900A (en) 1999-03-05 2000-03-03 Human secretory proteins
JP2000602763A JP2002537805A (en) 1999-03-05 2000-03-03 Human secretory protein
CA002363684A CA2363684A1 (en) 1999-03-05 2000-03-03 Human secretory proteins
EP00912168A EP1165766A2 (en) 1999-03-05 2000-03-03 Human secretory proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12311799P 1999-03-05 1999-03-05
US60/123,117 1999-03-05

Publications (2)

Publication Number Publication Date
WO2000052151A2 WO2000052151A2 (en) 2000-09-08
WO2000052151A3 true WO2000052151A3 (en) 2001-04-26

Family

ID=22406805

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/005621 Ceased WO2000052151A2 (en) 1999-03-05 2000-03-03 Human secretory proteins

Country Status (5)

Country Link
EP (1) EP1165766A2 (en)
JP (1) JP2002537805A (en)
AU (1) AU3393900A (en)
CA (1) CA2363684A1 (en)
WO (1) WO2000052151A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7414112B2 (en) 1998-10-08 2008-08-19 Genentech, Inc. Antibodies to PRO1550 polypeptides
CA2585822A1 (en) * 2000-06-02 2001-12-13 Genentech, Inc. Breast, rectal, colon and lung tumour marker pro19628 polypeptide and encoding nucleic acid
US7335731B2 (en) 2000-07-25 2008-02-26 Genentech, Inc. PRO4332 polypeptides
EP1666490A3 (en) * 2000-07-25 2006-11-02 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6630325B1 (en) * 2000-10-19 2003-10-07 Maine Medical Center Research Institute Compositions, methods and kits relating to remodel
CA2433802A1 (en) * 2001-01-16 2002-07-25 Incyte Genomics, Inc. Secretory molecules
EP2305710A3 (en) 2002-06-03 2013-05-29 Genentech, Inc. Synthetic antibody phage libraries
WO2004016636A1 (en) * 2002-08-14 2004-02-26 Lg Life Sciences Ltd. Gene families associated with stomach cancer
US7452968B2 (en) * 2003-01-02 2008-11-18 University Of Southern California Secreted protein factor and cell membrane-bound splice variant
WO2005034732A2 (en) * 2003-10-07 2005-04-21 Millennium Pharmaceuticals, Inc. Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
US10550173B2 (en) 2015-02-19 2020-02-04 Compugen, Ltd. PVRIG polypeptides and methods of treatment
IL254039B2 (en) 2015-02-19 2023-12-01 Compugen Ltd Anti-PVRIG antibodies and methods of use
KR102585976B1 (en) 2016-08-17 2023-10-05 컴퓨젠 엘티디. Anti-tigit antibodies, anti-pvrig antibodies and combinations thereof
JP7348072B2 (en) 2017-06-01 2023-09-20 コンピュジェン リミテッド Triple combination antibody therapy

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998030696A2 (en) * 1997-01-13 1998-07-16 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1998032853A2 (en) * 1997-01-24 1998-07-30 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1998040486A2 (en) * 1997-03-14 1998-09-17 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1999022243A1 (en) * 1997-10-24 1999-05-06 Human Genome Sciences, Inc. 148 human secreted proteins

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998030696A2 (en) * 1997-01-13 1998-07-16 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1998032853A2 (en) * 1997-01-24 1998-07-30 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1998040486A2 (en) * 1997-03-14 1998-09-17 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1999022243A1 (en) * 1997-10-24 1999-05-06 Human Genome Sciences, Inc. 148 human secreted proteins

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JACOBS K A ET AL: "A genetic selection for isolating cDNAs encoding secreted proteins", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES,GB,ELSEVIER SCIENCE PUBLISHERS, BARKING, vol. 198, no. 1-2, 1 October 1997 (1997-10-01), pages 289 - 296, XP004116069, ISSN: 0378-1119 *
SHIROZU M ET AL: "CHARACTERIZATION OF NOVEL SECRETED AND MEMBRANE PROTEINS ISOLATED BY THE SIGNAL SEQUENCE TRAP METHOD", GENOMICS,US,ACADEMIC PRESS, SAN DIEGO, vol. 37, no. 3, 1 November 1996 (1996-11-01), pages 273 - 280, XP002054773, ISSN: 0888-7543 *

Also Published As

Publication number Publication date
JP2002537805A (en) 2002-11-12
EP1165766A2 (en) 2002-01-02
CA2363684A1 (en) 2000-09-08
WO2000052151A2 (en) 2000-09-08
AU3393900A (en) 2000-09-21

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