WO2000055629A3 - Methods of diagnosing and treating breast cancer - Google Patents

Methods of diagnosing and treating breast cancer Download PDF

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Publication number
WO2000055629A3
WO2000055629A3 PCT/US2000/006952 US0006952W WO0055629A3 WO 2000055629 A3 WO2000055629 A3 WO 2000055629A3 US 0006952 W US0006952 W US 0006952W WO 0055629 A3 WO0055629 A3 WO 0055629A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
breast cancer
diagnosing
treating breast
breast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/006952
Other languages
French (fr)
Other versions
WO2000055629A2 (en
Inventor
David Mack
Kurt C Gish
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EOS Biotechnology Inc
Original Assignee
EOS Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EOS Biotechnology Inc filed Critical EOS Biotechnology Inc
Priority to CA002368152A priority Critical patent/CA2368152A1/en
Priority to AU37527/00A priority patent/AU3752700A/en
Priority to EP00916419A priority patent/EP1159619A2/en
Priority to MXPA01009367A priority patent/MXPA01009367A/en
Priority to JP2000605210A priority patent/JP2004537710A/en
Priority to US09/642,034 priority patent/US6762020B1/en
Publication of WO2000055629A2 publication Critical patent/WO2000055629A2/en
Priority to US09/747,371 priority patent/US6750013B2/en
Publication of WO2000055629A3 publication Critical patent/WO2000055629A3/en
Anticipated expiration legal-status Critical
Priority to US10/769,612 priority patent/US20040141983A1/en
Priority to US12/796,244 priority patent/US8313745B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Described herein are methods that can be used for diagnosis and prognosis of breast cancer. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate breast cancer. Additionally, methods and molecular targets (genes and their products) for therapeutic intervention in breast and other cancers are described. The methods involve the use of proteins like BCH1.
PCT/US2000/006952 1999-03-15 2000-03-15 Methods of diagnosing and treating breast cancer Ceased WO2000055629A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CA002368152A CA2368152A1 (en) 1999-03-15 2000-03-15 Novel methods of diagnosing and treating breast cancer, compositions, and methods of screening for breast cancer modulators
AU37527/00A AU3752700A (en) 1999-03-15 2000-03-15 Novel methods of diagnosing and treating breast cancer, compositions, and methods of screening for breast cancer modulators
EP00916419A EP1159619A2 (en) 1999-03-15 2000-03-15 Methods of diagnosing and treating breast cancer
MXPA01009367A MXPA01009367A (en) 1999-03-15 2000-03-15 Novel methods of diagnosing and treating breast cancer, compositions, and methods of screening for breast cancer modulators.
JP2000605210A JP2004537710A (en) 1999-03-15 2000-03-15 Novel methods and compositions for diagnosing and treating breast cancer and methods for selecting for breast cancer modulators
US09/642,034 US6762020B1 (en) 1999-03-15 2000-08-18 Methods of diagnosing breast cancer
US09/747,371 US6750013B2 (en) 1999-12-02 2000-12-21 Methods for detection and diagnosing of breast cancer
US10/769,612 US20040141983A1 (en) 1999-03-15 2004-01-29 Compositions against cancer antigen LIV-1 and uses thereof
US12/796,244 US8313745B2 (en) 1999-03-15 2010-06-08 Compositions against cancer antigen LIV-1 and uses thereof

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US26886599A 1999-03-15 1999-03-15
US09/268,865 1999-03-15
US44037099A 1999-11-12 1999-11-12
US43987899A 1999-11-12 1999-11-12
US09/439,878 1999-11-12
US09/440,370 1999-11-12
US44049399A 1999-11-15 1999-11-15
US09/440,493 1999-11-15
US44067699A 1999-11-16 1999-11-16
US44067799A 1999-11-16 1999-11-16
US09/440,677 1999-11-16
US09/440,676 1999-11-16
US45081099A 1999-11-29 1999-11-29
US09/450,810 1999-11-29
US45313799A 1999-12-02 1999-12-02
US09/453,137 1999-12-02

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US52536100A Continuation-In-Part 1999-03-15 2000-03-15

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US45313799A Continuation-In-Part 1999-03-15 1999-12-02
US09/642,034 Continuation-In-Part US6762020B1 (en) 1999-03-15 2000-08-18 Methods of diagnosing breast cancer

Publications (2)

Publication Number Publication Date
WO2000055629A2 WO2000055629A2 (en) 2000-09-21
WO2000055629A3 true WO2000055629A3 (en) 2001-03-22

Family

ID=27575318

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/006952 Ceased WO2000055629A2 (en) 1999-03-15 2000-03-15 Methods of diagnosing and treating breast cancer

Country Status (4)

Country Link
EP (1) EP1159619A2 (en)
AU (1) AU3752700A (en)
CA (1) CA2368152A1 (en)
WO (1) WO2000055629A2 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2053129A3 (en) 1998-09-02 2009-08-19 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating various cancers
US6902892B1 (en) 1998-10-19 2005-06-07 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
US6962980B2 (en) 1999-09-24 2005-11-08 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian cancer
US6468546B1 (en) 1998-12-17 2002-10-22 Corixa Corporation Compositions and methods for therapy and diagnosis of ovarian cancer
US7888477B2 (en) 1998-12-17 2011-02-15 Corixa Corporation Ovarian cancer-associated antibodies and kits
WO2001035811A2 (en) * 1999-11-16 2001-05-25 Eos Biotechnology, Inc. Methods of diagnosing and determining prognosis of breast cancer
US7238471B1 (en) 1999-11-23 2007-07-03 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating breast cancer
JP2003526342A (en) * 1999-11-23 2003-09-09 ディアデクサス インコーポレーテッド Novel methods of diagnosing, monitoring, staging, imaging and treating breast cancer
JP2003523207A (en) 2000-01-25 2003-08-05 ジェネンテック・インコーポレーテッド LIV-1-related proteins, polynucleotides encoding them, and their use in treating cancer
US7534417B2 (en) 2000-02-24 2009-05-19 Agensys, Inc. 103P2D6: tissue specific protein highly expressed in various cancers
GB0004576D0 (en) * 2000-02-25 2000-04-19 Oxford Glycosciences Uk Ltd Proteins
WO2001072826A2 (en) * 2000-03-24 2001-10-04 Genzyme Corporation Oncogenic osteomalacia-related gene 1
JP2004500852A (en) * 2000-05-19 2004-01-15 エフ．　ホフマン−ラ　ロシュ　アーゲー Process for determining the tumoricidal potential of a sample by using nucleic acids that are down-regulated in human tumor cells
US20060063230A1 (en) 2000-12-27 2006-03-23 Roman Naworth Sulfatases and methods of use thereof
US20030148920A1 (en) * 2000-12-27 2003-08-07 Steven Rosen Sulfatases and methods of use thereof
WO2002074906A2 (en) * 2001-03-16 2002-09-26 Eli Lilly And Company Lp mammalian proteins; related reagents
US6461847B1 (en) * 2001-03-19 2002-10-08 Applera Corporation Polynucleotides encoding human estrone sulfatases
AU2002367317A1 (en) 2001-12-31 2003-07-24 Dana-Farber Cancer Institute, Inc. Psoriasin expression by breast epithelial cells
DK2258872T3 (en) * 2002-03-13 2013-11-18 Genomic Health Inc Gene expression profiling in tumor tissue biopsies
JP2007504842A (en) * 2003-05-29 2007-03-08 ミレニアム ファーマシューティカルズ， インコーポレイテッド Compositions, kits and methods for identification, evaluation, prevention and treatment of breast cancer
JP4912894B2 (en) 2004-02-19 2012-04-11 イェール ユニバーシティー Identification of oncoprotein biomarkers using proteomic technology
EP1805676A1 (en) * 2004-09-22 2007-07-11 Tripath Imaging, Inc. Methods and computer program products for analysis and optimization of marker candidates for cancer prognosis
US8093362B2 (en) 2005-12-06 2012-01-10 Kyowa Hakko Kirin Co., Ltd. Anti-PERP recombinant antibody

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5514554A (en) * 1991-08-22 1996-05-07 Becton Dickinson And Company Methods and compositions for cancer therapy and for prognosticating responses to cancer therapy
WO1998018945A1 (en) * 1996-10-31 1998-05-07 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
WO1998034118A1 (en) * 1997-01-30 1998-08-06 Yale University Diagnostic methods and compositions based on the distribution of rad51
WO1999023230A1 (en) * 1997-10-31 1999-05-14 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
WO1999025877A1 (en) * 1997-11-18 1999-05-27 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
WO1999033869A2 (en) * 1997-12-24 1999-07-08 Corixa Corporation Compounds for immunotherapy and diagnosis of breast cancer and methods for their use
WO2000008210A1 (en) * 1998-08-04 2000-02-17 Diadexus Llc A novel method of diagnosing, monitoring, staging, imaging and treating breast cancer

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5514554A (en) * 1991-08-22 1996-05-07 Becton Dickinson And Company Methods and compositions for cancer therapy and for prognosticating responses to cancer therapy
WO1998018945A1 (en) * 1996-10-31 1998-05-07 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
WO1998034118A1 (en) * 1997-01-30 1998-08-06 Yale University Diagnostic methods and compositions based on the distribution of rad51
WO1999023230A1 (en) * 1997-10-31 1999-05-14 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
WO1999025877A1 (en) * 1997-11-18 1999-05-27 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
WO1999033869A2 (en) * 1997-12-24 1999-07-08 Corixa Corporation Compounds for immunotherapy and diagnosis of breast cancer and methods for their use
WO2000008210A1 (en) * 1998-08-04 2000-02-17 Diadexus Llc A novel method of diagnosing, monitoring, staging, imaging and treating breast cancer

Also Published As

Publication number Publication date
AU3752700A (en) 2000-10-04
WO2000055629A2 (en) 2000-09-21
CA2368152A1 (en) 2000-09-21
EP1159619A2 (en) 2001-12-05

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