WO2000064425A3 - Miotic agents and hypertonic agents containing ophthalmic compositions - Google Patents

Miotic agents and hypertonic agents containing ophthalmic compositions Download PDF

Info

Publication number
WO2000064425A3
WO2000064425A3 PCT/IT2000/000151 IT0000151W WO0064425A3 WO 2000064425 A3 WO2000064425 A3 WO 2000064425A3 IT 0000151 W IT0000151 W IT 0000151W WO 0064425 A3 WO0064425 A3 WO 0064425A3
Authority
WO
WIPO (PCT)
Prior art keywords
agents
hypertonic
ophthalmic compositions
miotic
resulting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IT2000/000151
Other languages
French (fr)
Other versions
WO2000064425A2 (en
Inventor
Enrico Boldrini
Dario Ercole Severino
Giorgio Panelli
Pietro Bianchini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farmigea SpA
Original Assignee
Farmigea SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmigea SpA filed Critical Farmigea SpA
Priority to DE60000736T priority Critical patent/DE60000736T2/en
Priority to CA002370895A priority patent/CA2370895A1/en
Priority to AT00927713T priority patent/ATE227135T1/en
Priority to EP00927713A priority patent/EP1173207B1/en
Priority to AU46099/00A priority patent/AU4609900A/en
Publication of WO2000064425A2 publication Critical patent/WO2000064425A2/en
Publication of WO2000064425A3 publication Critical patent/WO2000064425A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)

Abstract

Ophthalmic compositions able to reduce the impairments of the visual function (like halos, glare and reduction of the night and twilight vision) resulting from keratectomy operations carried out both with laser and by conventional techniques, from intraocular lens implantation (cataract surgery) and also resulting from various chronic pathologies affecting the anterior segment of the eyeball, such as the degenerations of the corneal tissue, which compositions contain one or more miotic agents, such as cholinomimetic active agents and cholinesterase inhibitors, in combination with one or more hypertonic agents, such as sulfacetamide and derivatives thereof, sodium chloride, glucose and glycerol.
PCT/IT2000/000151 1999-04-26 2000-04-14 Miotic agents and hypertonic agents containing ophthalmic compositions Ceased WO2000064425A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE60000736T DE60000736T2 (en) 1999-04-26 2000-04-14 MIOTIC ACTIVE SUBSTANCES AND OPHTHALMIC COMPOSITIONS CONTAINING HYPERTONIC ACTIVE SUBSTANCES
CA002370895A CA2370895A1 (en) 1999-04-26 2000-04-14 Miotic agents and hypertonic agents containing ophthalmic compositions
AT00927713T ATE227135T1 (en) 1999-04-26 2000-04-14 OPHTHALMIC COMPOSITIONS CONTAINING MIOTIC ACTIVES AND HYPERTONIC ACTIVES
EP00927713A EP1173207B1 (en) 1999-04-26 2000-04-14 Miotic agents and hypertonic agents containing ophthalmic compositions
AU46099/00A AU4609900A (en) 1999-04-26 2000-04-14 Ophthalmic compositions for the treatment of visual disorders characterised by areduced contrast sensitivity

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999RM000259A IT1306135B1 (en) 1999-04-26 1999-04-26 OPHTHALMIC COMPOSITIONS FOR THE TREATMENT OF VISUAL TURBES CHARACTERIZED BY REDUCED SENSITIVITY TO CONTRAST.
ITRM99A000259 1999-04-26

Publications (2)

Publication Number Publication Date
WO2000064425A2 WO2000064425A2 (en) 2000-11-02
WO2000064425A3 true WO2000064425A3 (en) 2001-04-12

Family

ID=11406726

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2000/000151 Ceased WO2000064425A2 (en) 1999-04-26 2000-04-14 Miotic agents and hypertonic agents containing ophthalmic compositions

Country Status (7)

Country Link
EP (1) EP1173207B1 (en)
AT (1) ATE227135T1 (en)
AU (1) AU4609900A (en)
CA (1) CA2370895A1 (en)
DE (1) DE60000736T2 (en)
IT (1) IT1306135B1 (en)
WO (1) WO2000064425A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6540990B2 (en) 2000-09-22 2003-04-01 Gerard M. Nolan Physiological method of improving vision
WO2002049612A2 (en) * 2000-12-20 2002-06-27 Alcon, Inc. Hypertonic ophthalmic irrigation solution adapted for use in lasik surgery
ITMI20010708A1 (en) * 2001-04-03 2002-10-03 Alessandro Randazzo PHARMACOLOGICAL TREATMENT OF NIGHT BLINDS AND GHOST IMAGES WITH DILUTED PARASYMPATHOMYMETICS ACECLIDINE / PILOCARPINE AFTER INTER
US10507245B2 (en) * 2012-07-19 2019-12-17 Luis Felipe Vejarano Restrepo Ophthalmic formulation and method for ameliorating presbyopia
HUE058931T2 (en) * 2018-04-24 2022-09-28 Allergan Inc The use of pilocarpine hydrochloride in the treatment of presbyopia
US11273141B2 (en) 2020-05-18 2022-03-15 Vyluma Inc. Low-dose carbachol compositions and methods for treatment of night vision disturbance
JP7766680B2 (en) * 2020-09-11 2025-11-10 イントラタス－ネバダ インコーポレイテッド Compositions and methods for treating presbyopia, hyperopia, astigmatism, reduced stereopsis, and reduced contrast sensitivity - Patents.com

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590207A (en) * 1984-01-18 1986-05-20 Eisai Co., Ltd. Therapeutic and/or preventive ophthalmic solution for intraocular hypertension and glaucoma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590207A (en) * 1984-01-18 1986-05-20 Eisai Co., Ltd. Therapeutic and/or preventive ophthalmic solution for intraocular hypertension and glaucoma

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CONRAD, J. M. ET AL: "Influence of tonicity and pH on lacrimation and ocular drug bioavailability", J. PARENTER. DRUG ASSOC. (1978), 32(4), 149-61, XP000911937 *
MARISI A. ET AL: "Hypertonic saline solution in corneal edema.", ANNALS OF OPHTHALMOLOGY, (1975) 7/2 (229-233). CODEN: ANOPB5, XP000912190 *

Also Published As

Publication number Publication date
EP1173207A2 (en) 2002-01-23
CA2370895A1 (en) 2000-11-02
ATE227135T1 (en) 2002-11-15
WO2000064425A2 (en) 2000-11-02
EP1173207B1 (en) 2002-11-06
ITRM990259A1 (en) 2000-10-26
DE60000736T2 (en) 2003-07-17
IT1306135B1 (en) 2001-05-30
DE60000736D1 (en) 2002-12-12
AU4609900A (en) 2000-11-10

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