WO2000065344A3 - Biological indicators for validating a prion sterilization-process - Google Patents

Biological indicators for validating a prion sterilization-process Download PDF

Info

Publication number
WO2000065344A3
WO2000065344A3 PCT/CA2000/000446 CA0000446W WO0065344A3 WO 2000065344 A3 WO2000065344 A3 WO 2000065344A3 CA 0000446 W CA0000446 W CA 0000446W WO 0065344 A3 WO0065344 A3 WO 0065344A3
Authority
WO
WIPO (PCT)
Prior art keywords
prion
validating
sterilization
biological indicators
indicators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CA2000/000446
Other languages
French (fr)
Other versions
WO2000065344A2 (en
Inventor
Pierre Belhumeur
Karine Julien
Maryam Tabrizian
L Hocine Yahia
Richard Marchand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Montreal
Original Assignee
Universite de Montreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Montreal filed Critical Universite de Montreal
Priority to CA2367688A priority Critical patent/CA2367688C/en
Priority to AU42789/00A priority patent/AU767097B2/en
Priority to BR0010007-2A priority patent/BR0010007A/en
Priority to NZ514929A priority patent/NZ514929A/en
Priority to JP2000614033A priority patent/JP2002542775A/en
Priority to EP00922360A priority patent/EP1173603B1/en
Priority to US09/980,649 priority patent/US7851178B1/en
Priority to DE60035104T priority patent/DE60035104T2/en
Priority to DK00922360T priority patent/DK1173603T3/en
Publication of WO2000065344A2 publication Critical patent/WO2000065344A2/en
Publication of WO2000065344A3 publication Critical patent/WO2000065344A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/22—Testing for sterility conditions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention relates to a method of evaluating the efficiency of sterilization processes by measurement of degradation level of prion protein indicators. When exposed to sterilization conditions, prion indicators are degraded in a manner to proportionally indicate the level of degradation of prion proteins themselves on medical devices or other surfaces usable in surgery and health cares.
PCT/CA2000/000446 1999-04-26 2000-04-20 Biological indicators for validating a prion sterilization-process Ceased WO2000065344A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CA2367688A CA2367688C (en) 1999-04-26 2000-04-20 Biological indicators for validating a prion sterilization-process
AU42789/00A AU767097B2 (en) 1999-04-26 2000-04-20 Biological indicators for validating a prion sterilization process
BR0010007-2A BR0010007A (en) 1999-04-26 2000-04-20 Biological indicators for validating a prion sterilization process
NZ514929A NZ514929A (en) 1999-04-26 2000-04-20 Biological indicators for validating a prion sterilization process
JP2000614033A JP2002542775A (en) 1999-04-26 2000-04-20 Biological indicators to evaluate the prion sterilization process
EP00922360A EP1173603B1 (en) 1999-04-26 2000-04-20 Biological indicators for validating a prion sterilization-process
US09/980,649 US7851178B1 (en) 1999-04-26 2000-04-20 Biological indicators for validating a prion sterilization-process
DE60035104T DE60035104T2 (en) 1999-04-26 2000-04-20 BIOLOGICAL INDICATORS FOR THE STATEMENT OF VALIDITY OF A PRION-STERILIZATION PROCESS
DK00922360T DK1173603T3 (en) 1999-04-26 2000-04-20 Biological indicators to validate a prion sterilization process

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13094599P 1999-04-26 1999-04-26
US60/130,945 1999-04-26

Publications (2)

Publication Number Publication Date
WO2000065344A2 WO2000065344A2 (en) 2000-11-02
WO2000065344A3 true WO2000065344A3 (en) 2001-02-22

Family

ID=22447121

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2000/000446 Ceased WO2000065344A2 (en) 1999-04-26 2000-04-20 Biological indicators for validating a prion sterilization-process

Country Status (15)

Country Link
US (1) US7851178B1 (en)
EP (1) EP1173603B1 (en)
JP (1) JP2002542775A (en)
KR (1) KR100881121B1 (en)
AT (1) ATE364093T1 (en)
AU (1) AU767097B2 (en)
BR (1) BR0010007A (en)
CA (1) CA2367688C (en)
DE (1) DE60035104T2 (en)
DK (1) DK1173603T3 (en)
ES (1) ES2287010T3 (en)
NZ (1) NZ514929A (en)
PT (1) PT1173603E (en)
WO (1) WO2000065344A2 (en)
ZA (1) ZA200108328B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6322802B1 (en) 1999-06-01 2001-11-27 The Regents Of The University Of California Method of sterilizing
US6419916B1 (en) 1999-06-01 2002-07-16 The Regents Of The University Of California Assay for compounds which affect conformationally altered proteins
US6720355B2 (en) 1997-02-21 2004-04-13 The Regents Of The University Of California Sodium dodecyl sulfate compositions for inactivating prions
US6719988B2 (en) 1997-02-21 2004-04-13 The Regents Of The University Of California Antiseptic compositions for inactivating prions
US20020192731A1 (en) * 2001-04-12 2002-12-19 H. Shih Jason C. Method and composition for sterilizing surgical instruments
GB0110191D0 (en) * 2001-04-25 2001-06-20 Oxford Instr Plasma Technology Sterilization method
US7090808B2 (en) 2001-07-09 2006-08-15 Pharmaceutical Systems, Inc. Apparatus for testing sterilization methods and materials
GB0316520D0 (en) * 2003-07-15 2003-08-20 Sec Dep For The Home Departmen Improvements in and relating to items and their treatment
US20080206801A1 (en) * 2007-02-27 2008-08-28 Steris Inc. Biological indicator for use with vaporous microbial deactivating agents and method for making same
US10466245B2 (en) 2008-02-20 2019-11-05 The Secretary Of State For Health Covalently linked thermostable kinase for decontamination process validation
CN101481729B (en) * 2009-01-21 2014-04-16 辽宁大学 High-sensitivity method for screening anti-prion medicament by using gene mutation yeast cell
CN101858910B (en) * 2010-03-25 2013-03-27 辽宁大学 Method for precisely and quantitatively detecting function effect of anti-prion medicament at protein level
US20140147882A1 (en) * 2011-07-18 2014-05-29 Luxcel Biosciences Ltd. Method and device for detection and quantification of thermoduric microorganisms in a product
RU2582221C1 (en) * 2014-09-29 2016-04-20 Общество с ограниченной ответственностью "Научно-производственная фирма "ВИНАР" Chemical indicator of ozone sterilisation process and manufacturing method thereof
EP3436085A4 (en) * 2016-03-29 2020-07-29 Oneighty°C Technologies Corporation METHOD FOR QUICK DETERMINING EFFECTIVE STERILIZATION, DEIMMUNIZATION AND / OR DISINFECTION
KR102369984B1 (en) 2019-05-27 2022-04-05 (주)에이트원 Method for managing for heavy equipment, and computer program recorded on record-medium for executing method therefor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408191B (en) * 1991-08-19 2001-09-25 Haemosan Erzeugung Pharmazeuti METHOD FOR INACTIVATING PRIONS
US5357636A (en) * 1992-06-30 1994-10-25 Dresdner Jr Karl P Flexible protective medical gloves and methods for their use
AU687819B2 (en) * 1993-08-09 1998-03-05 Johnson & Johnson Medical, Inc. Self-contained biological indicator
US5801010A (en) * 1997-03-17 1998-09-01 Surigot, Inc. Self-contained biological indicator for non traditional sterilization methods
JPH11299867A (en) * 1998-04-21 1999-11-02 Nihon Pharmaceutical Co Ltd Disinfection of medical equipment
GB9810859D0 (en) * 1998-05-20 1998-07-22 Zeneca Ltd Crystallisation process

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
R.N. ROSENBERG ET AL.: "Precautions in handling tissues, fluids and other contaminated materials from patients with documented or suspected Creutzfeldt-Jakob disease", ANNALES OF NEUROLOGY, vol. 19, no. 1, 1986, BOSTON MA USA, pages 75 - 77, XP000923098 *

Also Published As

Publication number Publication date
KR100881121B1 (en) 2009-02-03
AU4278900A (en) 2000-11-10
PT1173603E (en) 2007-08-23
NZ514929A (en) 2002-12-20
ZA200108328B (en) 2002-10-10
WO2000065344A2 (en) 2000-11-02
DK1173603T3 (en) 2007-10-01
DE60035104T2 (en) 2008-02-07
CA2367688C (en) 2010-06-22
ES2287010T3 (en) 2007-12-16
ATE364093T1 (en) 2007-06-15
EP1173603A2 (en) 2002-01-23
KR20020008154A (en) 2002-01-29
EP1173603B1 (en) 2007-06-06
CA2367688A1 (en) 2000-11-02
BR0010007A (en) 2002-01-15
DE60035104D1 (en) 2007-07-19
US7851178B1 (en) 2010-12-14
AU767097B2 (en) 2003-10-30
JP2002542775A (en) 2002-12-17

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