WO2000068234A3 - Process for the preparation of cefpodoxime acid - Google Patents

Process for the preparation of cefpodoxime acid Download PDF

Info

Publication number
WO2000068234A3
WO2000068234A3 PCT/IB2000/000585 IB0000585W WO0068234A3 WO 2000068234 A3 WO2000068234 A3 WO 2000068234A3 IB 0000585 W IB0000585 W IB 0000585W WO 0068234 A3 WO0068234 A3 WO 0068234A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
cefpodoxime
cefpodoxime acid
acid
converted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2000/000585
Other languages
French (fr)
Other versions
WO2000068234A2 (en
Inventor
Yatendra Kumar
Rakesh Kumar Arora
Kaptan Singh
Hashim Nizar
Shantanu De
Jag Mohan Khanna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Priority to EP00969048A priority Critical patent/EP1178992A2/en
Priority to HK02105883.7A priority patent/HK1044761A1/en
Priority to AU72243/00A priority patent/AU7224300A/en
Publication of WO2000068234A2 publication Critical patent/WO2000068234A2/en
Publication of WO2000068234A3 publication Critical patent/WO2000068234A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

A new process is described for the preparation of cefpodoxime acid, which may then be converted into cefpodoxime proxetil by methods known in the art.
PCT/IB2000/000585 1999-05-07 2000-05-05 Process for the preparation of cefpodoxime acid Ceased WO2000068234A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP00969048A EP1178992A2 (en) 1999-05-07 2000-05-05 Process for the preparation of cefpodoxime acid
HK02105883.7A HK1044761A1 (en) 1999-05-07 2000-05-05 Process for the preparation of cefpodoxime acid
AU72243/00A AU7224300A (en) 1999-05-07 2000-05-05 Process for the preparation of cefpodoxime acid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30701099A 1999-05-07 1999-05-07
US09/307,010 1999-05-07

Publications (2)

Publication Number Publication Date
WO2000068234A2 WO2000068234A2 (en) 2000-11-16
WO2000068234A3 true WO2000068234A3 (en) 2001-02-08

Family

ID=23187851

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2000/000585 Ceased WO2000068234A2 (en) 1999-05-07 2000-05-05 Process for the preparation of cefpodoxime acid

Country Status (4)

Country Link
EP (1) EP1178992A2 (en)
AU (1) AU7224300A (en)
HK (1) HK1044761A1 (en)
WO (1) WO2000068234A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037833A1 (en) * 2002-10-24 2004-05-06 Orchid Chemicals & Pharmaceuticals Ltd Process for the preparation of cephalosporin antibiotics
WO2011077217A1 (en) * 2009-12-21 2011-06-30 Nectar Lifesciences Ltd. An improved process for the preparation of cefpodoxime acid
CN106046024B (en) * 2016-06-30 2019-01-15 齐鲁动物保健品有限公司 A kind of preparation method of Cefpodoxime Proxetil
CN111320514A (en) * 2020-04-03 2020-06-23 南京昊绿生物科技有限公司 Synthesis method of cefpodoxime D3
CN116003438B (en) * 2022-12-28 2025-09-05 广药白云山化学制药(珠海)有限公司 A preparation method of cephalosporin intermediate

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034536A2 (en) * 1980-02-18 1981-08-26 Roussel-Uclaf Oxime derivatives of 3-alkyloxy- or 3-alkylthiomethyl 7-amino-thiazolylacetamido cephalosporanic acid, their preparation, their use as medicaments and compositions containing them
JPS60260584A (en) * 1985-05-14 1985-12-23 Sankyo Co Ltd Cephalosporin derivative and its preparation
JPS60260583A (en) * 1985-05-14 1985-12-23 Sankyo Co Ltd Preparation of cephalosporin derivative
EP0531875A2 (en) * 1991-09-07 1993-03-17 Hoechst Aktiengesellschaft Diastereomers of the 3-cephem-4-carboxylic acid-1-(-isopropoxycarbonyloxy)ethylester and process for their preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0037380B1 (en) 1980-03-28 1984-09-12 BIOCHEMIE Gesellschaft m.b.H. New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production
TW538045B (en) 1997-01-16 2003-06-21 Biochemie Gmbh Process for purifying cefixime

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034536A2 (en) * 1980-02-18 1981-08-26 Roussel-Uclaf Oxime derivatives of 3-alkyloxy- or 3-alkylthiomethyl 7-amino-thiazolylacetamido cephalosporanic acid, their preparation, their use as medicaments and compositions containing them
US4992431A (en) * 1980-02-18 1991-02-12 Rousseluclaf Cephalosporins
JPS60260584A (en) * 1985-05-14 1985-12-23 Sankyo Co Ltd Cephalosporin derivative and its preparation
JPS60260583A (en) * 1985-05-14 1985-12-23 Sankyo Co Ltd Preparation of cephalosporin derivative
EP0531875A2 (en) * 1991-09-07 1993-03-17 Hoechst Aktiengesellschaft Diastereomers of the 3-cephem-4-carboxylic acid-1-(-isopropoxycarbonyloxy)ethylester and process for their preparation

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 108, no. 5, 1 February 1988, Columbus, Ohio, US; abstract no. 55704m, FUJIMOTO K ET AL: "Studies on orally active cephalosporin esters" page 687; column 2; XP002901354 *
J. ANTIBIOT., vol. 40, no. 3, 1987, pages 370 - 384 *
PATENT ABSTRACTS OF JAPAN vol. 010, no. 136 (C - 347) 20 May 1986 (1986-05-20) *
See also references of EP1178992A2 *

Also Published As

Publication number Publication date
WO2000068234A2 (en) 2000-11-16
EP1178992A2 (en) 2002-02-13
AU7224300A (en) 2000-11-21
HK1044761A1 (en) 2002-11-01

Similar Documents

Publication Publication Date Title
BG106786A (en) Process for the preparation of amorphous atorvastatin
PL322611A1 (en) Methods of obtaining l-amini acid by fermentation, dna as well as micro-organism
WO2001034835A3 (en) Method for the production of biopolymers with modified properties
AU6283700A (en) Preparation of chemical pulp and xylose, utilizing a direct acid hydrolysis on the pulp
WO2003012082A3 (en) Method for modulating stem cell differentiation using stem loop rna
AU2001277545A1 (en) Process for the production of 2-hydroxy-4-methylmercaptobutyric acid
WO2000068234A3 (en) Process for the preparation of cefpodoxime acid
WO2002016322A3 (en) Process for the preparation of 2-aminoethylpyridines
EP0992503A4 (en) Process for producing isooxazolidinedione compound
CA2412049A1 (en) Process for the preparation of 5-aminosalicyclic acid
AU6578400A (en) Novel method for preparing benzoperhydroisoindole compounds
TR200201243T2 (en) High purity cefpodoxime proxetil preparation method.
EP0861838A3 (en) Process and intermediates for preparing cryptophycin compounds
CA2370956A1 (en) Method for causticisation of alkaline solutions
WO2000068290A3 (en) Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof
EP1229031A4 (en) METHOD FOR THE PRODUCTION OF 3,4-METHYLENE DIOXY ALMONIC ACID
WO1998034584A3 (en) Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
WO2000064882A3 (en) Enantiomers of mercapto lactones and processes for their synthesis
AU2002229706A1 (en) Process for the fermentative production of d-pantothenic acid
EP1270579A4 (en) PROCESS FOR THE PRODUCTION OF CAMPTOTHECIN
WO2001029024A3 (en) Method for preparing a thiophene derivative
AU2003282267A1 (en) An improved process for the preparation of cefpodoxime proxetil
WO2003007872A3 (en) Process for the preparation of citalopram hydrobromide
AU1552701A (en) Process for the production of 5-oxy-7-oxabicyclo-(4.1.0)hept-3-E NE-3-carboxylic acid esters
EP1258478A4 (en) Process for producing quinolonecarboxylic acids and intermediates thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2000969048

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2000969048

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 2000969048

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP