WO2000071185A3 - Needleless injector drug capsule - Google Patents

Needleless injector drug capsule Download PDF

Info

Publication number
WO2000071185A3
WO2000071185A3 PCT/GB2000/001922 GB0001922W WO0071185A3 WO 2000071185 A3 WO2000071185 A3 WO 2000071185A3 GB 0001922 W GB0001922 W GB 0001922W WO 0071185 A3 WO0071185 A3 WO 0071185A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
capsule
transparent
receiving
needleless injector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2000/001922
Other languages
French (fr)
Other versions
WO2000071185A2 (en
Inventor
Terence Edward Weston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Weston Medical Ltd
Original Assignee
Weston Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9911663.4A external-priority patent/GB9911663D0/en
Priority claimed from GBGB9924533.4A external-priority patent/GB9924533D0/en
Application filed by Weston Medical Ltd filed Critical Weston Medical Ltd
Priority to EP00931402A priority Critical patent/EP1180046A2/en
Priority to AU49358/00A priority patent/AU4935800A/en
Priority to JP2000619486A priority patent/JP2003500118A/en
Publication of WO2000071185A2 publication Critical patent/WO2000071185A2/en
Priority to US09/731,398 priority patent/US20010004682A1/en
Publication of WO2000071185A3 publication Critical patent/WO2000071185A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2044—Separating means having slits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3117—Means preventing contamination of the medicament compartment of a syringe
    • A61M2005/3118—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3117—Means preventing contamination of the medicament compartment of a syringe
    • A61M2005/3118—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula
    • A61M2005/312—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula comprising sealing means, e.g. severable caps, to be removed prior to injection by, e.g. tearing or twisting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3123—Details having air entrapping or venting means, e.g. purging channels in pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

A transparent needleless injector drug capsule suitable for prefilling with a liquid drug comprises a first inner layer of drug compatible transparent plastics defining a chamber for receiving a liquid drug and a second outer layer of transparent plastics forming a supporting sleeve around the first layer of plastics. Each of the first and second layers of transparent plastics is resistant to discolouration when irradiated by high energy radiation. Thus, a low cost, transparent, needleless injector drug capsule is provided which is capable of being sterilised by high energy irradiation. The capsule may define a body having a main chamber for receiving a liquid drug and for retaining a free piston in a sealing fit for subsequent use in the discharge of a drug, the body also having an extension chamber having an opening for receiving the free piston in a loose fit. The initial loose fitting of the piston allows penetration by a sterilization fluid, so that the drug capsule is capable of being assembled in clean conditions and subsequently sterilized by any known method.
PCT/GB2000/001922 1995-12-16 2000-05-19 Needleless injector drug capsule Ceased WO2000071185A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP00931402A EP1180046A2 (en) 1999-05-19 2000-05-19 Needleless injector drug capsule
AU49358/00A AU4935800A (en) 1999-05-19 2000-05-19 Needleless injector drug capsule
JP2000619486A JP2003500118A (en) 1999-05-19 2000-05-19 Needleless syringe drug capsule
US09/731,398 US20010004682A1 (en) 1995-12-16 2000-12-01 Needleless injector drug capsule

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9911663.4 1999-05-19
GBGB9911663.4A GB9911663D0 (en) 1999-05-19 1999-05-19 Needleless injector drug capsule
GBGB9924533.4A GB9924533D0 (en) 1999-10-15 1999-10-15 Needleless injector drug capsule
GB9924533.4 1999-10-15

Publications (2)

Publication Number Publication Date
WO2000071185A2 WO2000071185A2 (en) 2000-11-30
WO2000071185A3 true WO2000071185A3 (en) 2001-04-05

Family

ID=26315564

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/001922 Ceased WO2000071185A2 (en) 1995-12-16 2000-05-19 Needleless injector drug capsule

Country Status (4)

Country Link
EP (1) EP1180046A2 (en)
JP (1) JP2003500118A (en)
AU (1) AU4935800A (en)
WO (1) WO2000071185A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8591457B2 (en) 2005-08-10 2013-11-26 Alza Corporation Method for making a needle-free jet injection drug delivery device

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2465502C (en) 2001-11-09 2011-03-22 Pedro De La Serna Pneumatic powered autoinjector
CA2662579A1 (en) * 2006-11-01 2008-05-15 Alcon, Inc. Automatic gas filling consumable
DK2039382T3 (en) * 2007-09-01 2010-09-13 Hoffmann La Roche Sealing ampoule in two compression modes
GB2467904B (en) * 2009-02-17 2013-06-12 Oval Medical Technologies Ltd Drug container and delivery mechanism
GB2471304B (en) 2009-06-24 2013-12-11 Oval Medical Technologies Ltd A pre-filled syringe or autoinjector
GB2471726B (en) * 2009-07-10 2013-09-11 Oval Medical Technologies Ltd A pre-filled syringe including an oxygen absorber
US20140142500A1 (en) * 2012-04-23 2014-05-22 Zogenix, Inc. Piston closures for drug delivery capsules
JP6040025B2 (en) 2012-12-28 2016-12-07 株式会社大協精工 Medical syringe
BE1021349B1 (en) * 2014-10-10 2015-11-05 Hubert De Backer Nv CONNECTION CAP WITH BREAKING EDGE AND INJECTION SYRINGE WITH THE SAID CONNECTION CAP
KR101907552B1 (en) * 2018-05-03 2018-10-12 주식회사 피테크 Painless injection device without needle

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5312335A (en) * 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5503628A (en) * 1995-03-15 1996-04-02 Jettek, Inc. Patient-fillable hypodermic jet injector
WO1997013536A1 (en) * 1995-10-09 1997-04-17 Alain Moreau Defarges Needleless jet injection device comprising a moulded-on cartridge
WO1997022375A1 (en) * 1995-12-16 1997-06-26 Weston Medical Limited Needleless injector drug capsule and filling method
WO1997036785A1 (en) * 1996-04-02 1997-10-09 Weston Medical Limited Method of filling a drug capsule and article produced thereby
US5779668A (en) * 1995-03-29 1998-07-14 Abbott Laboratories Syringe barrel for lyophilization, reconstitution and administration
US5788670A (en) * 1994-12-22 1998-08-04 Schott Glas Dual chamber prefillable syringe and a method for the assembly and filling of same
US5875976A (en) * 1996-12-24 1999-03-02 Medi-Ject Corporation Locking mechanism for nozzle assembly
WO2000015281A1 (en) * 1998-09-15 2000-03-23 Weston Medical Limited Needleless injector cartridge
WO2000035520A1 (en) * 1998-12-18 2000-06-22 Biovalve Technologies, Inc. Injection devices

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4438360C2 (en) * 1994-10-27 1999-05-20 Schott Glas Pre-fillable, low-particle, sterile disposable syringe for the injection of preparations and methods for their manufacture

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5312335A (en) * 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5788670A (en) * 1994-12-22 1998-08-04 Schott Glas Dual chamber prefillable syringe and a method for the assembly and filling of same
US5503628A (en) * 1995-03-15 1996-04-02 Jettek, Inc. Patient-fillable hypodermic jet injector
US5779668A (en) * 1995-03-29 1998-07-14 Abbott Laboratories Syringe barrel for lyophilization, reconstitution and administration
WO1997013536A1 (en) * 1995-10-09 1997-04-17 Alain Moreau Defarges Needleless jet injection device comprising a moulded-on cartridge
WO1997022375A1 (en) * 1995-12-16 1997-06-26 Weston Medical Limited Needleless injector drug capsule and filling method
WO1997036785A1 (en) * 1996-04-02 1997-10-09 Weston Medical Limited Method of filling a drug capsule and article produced thereby
US5875976A (en) * 1996-12-24 1999-03-02 Medi-Ject Corporation Locking mechanism for nozzle assembly
WO2000015281A1 (en) * 1998-09-15 2000-03-23 Weston Medical Limited Needleless injector cartridge
WO2000035520A1 (en) * 1998-12-18 2000-06-22 Biovalve Technologies, Inc. Injection devices

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1180046A2 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8591457B2 (en) 2005-08-10 2013-11-26 Alza Corporation Method for making a needle-free jet injection drug delivery device
US8998881B2 (en) 2005-08-10 2015-04-07 Alza Corporation Method for delivering drugs to tissue under microjet propulsion

Also Published As

Publication number Publication date
AU4935800A (en) 2000-12-12
EP1180046A2 (en) 2002-02-20
WO2000071185A2 (en) 2000-11-30
JP2003500118A (en) 2003-01-07

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