WO2001000638A3 - Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses - Google Patents

Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses Download PDF

Info

Publication number
WO2001000638A3
WO2001000638A3 PCT/US2000/016658 US0016658W WO0100638A3 WO 2001000638 A3 WO2001000638 A3 WO 2001000638A3 US 0016658 W US0016658 W US 0016658W WO 0100638 A3 WO0100638 A3 WO 0100638A3
Authority
WO
WIPO (PCT)
Prior art keywords
diagnostic
nucleic acids
therapeutic
preventive
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/016658
Other languages
French (fr)
Other versions
WO2001000638A2 (en
Inventor
Susan J Kirst
Douglas A Holtzman
Christopher C Fraser
John D Sharp
Thomas S Barnes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Priority to EP00941494A priority Critical patent/EP1194534A4/en
Priority to AU56197/00A priority patent/AU5619700A/en
Publication of WO2001000638A2 publication Critical patent/WO2001000638A2/en
Publication of WO2001000638A3 publication Critical patent/WO2001000638A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides isolated nucleic acids encoding a variety of proteins and nucleic acids having diagnostic, preventive, therapeutic, and other uses. These nucleic acids and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.
PCT/US2000/016658 1999-06-29 2000-06-16 Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses Ceased WO2001000638A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP00941494A EP1194534A4 (en) 1999-06-29 2000-06-16 Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses
AU56197/00A AU5619700A (en) 1999-06-29 2000-06-16 Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34236499A 1999-06-29 1999-06-29
US09/342,364 1999-06-29

Publications (2)

Publication Number Publication Date
WO2001000638A2 WO2001000638A2 (en) 2001-01-04
WO2001000638A3 true WO2001000638A3 (en) 2001-07-05

Family

ID=23341516

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/016658 Ceased WO2001000638A2 (en) 1999-06-29 2000-06-16 Novel genes encoding proteins having diagnostic, preventive, therapeutic, and other uses

Country Status (3)

Country Link
EP (1) EP1194534A4 (en)
AU (1) AU5619700A (en)
WO (1) WO2001000638A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2371434A1 (en) * 1999-06-09 2000-12-14 Genentech, Inc. Compositions and methods for the treatment of tumor
CA2399652A1 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Methods and materials relating to neuronal guidance molecule-like (ngm-like) polypeptides and polynucleotides
EP1541677A4 (en) * 2002-07-10 2007-06-27 Takeda Pharmaceutical NEW PROTEINS AND THEIR USE
EP1447412A1 (en) * 2003-02-17 2004-08-18 Universiteit Utrecht Holding B.V. Method for the characterization of proteins, isolated proteins and uses therefore
WO2024138074A1 (en) * 2022-12-21 2024-06-27 Codexis, Inc. Engineered rnase inhibitor variants
CN116223818B (en) * 2023-05-09 2023-07-21 四川大学华西医院 Use of the DR3 protein detection reagent in the preparation of a kit for screening AECOPD and the kit for screening AECOPD

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995026201A1 (en) * 1994-03-28 1995-10-05 La Jolla Cancer Research Foundation Brevican, a glial cell proteoglycan
US5635370A (en) * 1994-04-08 1997-06-03 Yale University DNA encoding BEHAB, a brain hyaluronan-binding protein, and recombinant expression systems for production of BEHAB polypeptides
US20030092175A1 (en) * 1996-11-13 2003-05-15 Seishi Kato Human proteins having transmembrane domains and dnas encoding these proteins
US5952171A (en) * 1996-11-19 1999-09-14 Millennium Biotherapeutics, Inc. Method for identifying genes encoding secreted or membrane-associated proteins
JP2001509679A (en) * 1997-01-21 2001-07-24 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド Polynucleotides and polypeptides encoding the receptor
WO1998039446A2 (en) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 70 human secreted proteins
CA2371434A1 (en) * 1999-06-09 2000-12-14 Genentech, Inc. Compositions and methods for the treatment of tumor
JP2003527089A (en) * 1999-08-17 2003-09-16 インサイト・ゲノミックス・インコーポレイテッド Membrane-related proteins

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 1 February 1999 (1999-02-01), NCU-CGAP, XP002935220, accession no. EST Database accession no. AI304312 *
DATABASE GENBANK [online] 10 November 1998 (1998-11-10), NCI-CGAP, XP002935216, accession no. EST Database accession no. AI184538 *
DATABASE GENBANK [online] 30 March 1999 (1999-03-30), NCI-CGAP, XP002935219, accession no. EST Database accession no. AI380446 *
DATABASE GENBANK [online] 9 March 1998 (1998-03-09), HILLIER ET AL., XP002935217, accession no. EST Database accession no. AA176796 *
DATABASE GENBANK [online] 9 March 1998 (1998-03-09), HILLIER ET AL., XP002935218, accession no. EST Database accession no. AA173251 *
See also references of EP1194534A4 *

Also Published As

Publication number Publication date
EP1194534A2 (en) 2002-04-10
EP1194534A4 (en) 2004-03-24
WO2001000638A2 (en) 2001-01-04
AU5619700A (en) 2001-01-31

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