WO2001007024A3 - Paracetamol and drotaverine containing composition - Google Patents

Paracetamol and drotaverine containing composition Download PDF

Info

Publication number
WO2001007024A3
WO2001007024A3 PCT/HU2000/000086 HU0000086W WO0107024A3 WO 2001007024 A3 WO2001007024 A3 WO 2001007024A3 HU 0000086 W HU0000086 W HU 0000086W WO 0107024 A3 WO0107024 A3 WO 0107024A3
Authority
WO
WIPO (PCT)
Prior art keywords
paracetamol
drotaverine
containing composition
active ingredient
additional active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/HU2000/000086
Other languages
French (fr)
Other versions
WO2001007024A2 (en
Inventor
Morvai Magdolna Vitanyine
Peterne Kovacs
Mathe Irma Kalmanne
Boglarka Jakab
Erzsebet Vegeli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority to DK00949829T priority Critical patent/DK1200088T3/en
Priority to UA2002021475A priority patent/UA72535C2/en
Priority to EEP200200042A priority patent/EE04952B1/en
Priority to AU63088/00A priority patent/AU6308800A/en
Priority to HR20020071A priority patent/HRP20020071B1/en
Priority to SI200030163T priority patent/SI1200088T1/en
Priority to PL353209A priority patent/PL197749B1/en
Priority to EA200200211A priority patent/EA003779B1/en
Priority to DE60003188T priority patent/DE60003188T2/en
Priority to EP00949829A priority patent/EP1200088B1/en
Priority to MEP-185/08A priority patent/MEP18508A/en
Priority to AT00949829T priority patent/ATE241983T1/en
Priority to MEP-2008-185A priority patent/ME00088B/en
Publication of WO2001007024A2 publication Critical patent/WO2001007024A2/en
Publication of WO2001007024A3 publication Critical patent/WO2001007024A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to a stable, solid pharmaceutical composition comprising as active ingredients paracetamol and drotaverine hydrochloride in a mixture with one or more organic acid or potassium sorbate as stabilizers, one or more usually used pharmaceutical auxiliary materials and optionally additional active ingredient. As additional active ingredient codein phosphate may be used.
PCT/HU2000/000086 1999-07-28 2000-07-28 Paracetamol and drotaverine containing composition Ceased WO2001007024A2 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DK00949829T DK1200088T3 (en) 1999-07-28 2000-07-28 Composition containing paracetamol and drotaverine
UA2002021475A UA72535C2 (en) 1999-07-28 2000-07-28 Analgesic and antipyretic pharmaceutical composition and method for its manufacture
EEP200200042A EE04952B1 (en) 1999-07-28 2000-07-28 Pharmaceutical composition and method for its preparation
AU63088/00A AU6308800A (en) 1999-07-28 2000-07-28 Pharmaceutical composition and preparation thereof
HR20020071A HRP20020071B1 (en) 1999-07-28 2000-07-28 PHARMACEUTICAL COMPOSITIONS AND PREPARATION OF THE SAME
SI200030163T SI1200088T1 (en) 1999-07-28 2000-07-28 Paracetamol and drotaverine containing composition
PL353209A PL197749B1 (en) 1999-07-28 2000-07-28 Paracetamol and drotaverine containing composition
EA200200211A EA003779B1 (en) 1999-07-28 2000-07-28 Stable solid pharmaceutical composition based on paracetamol
DE60003188T DE60003188T2 (en) 1999-07-28 2000-07-28 COMPOSITION CONTAINING PARACETAMOL AND DROTAVERIN
EP00949829A EP1200088B1 (en) 1999-07-28 2000-07-28 Paracetamol and drotaverine containing composition
MEP-185/08A MEP18508A (en) 1999-07-28 2000-07-28 Pharmaceutical composition and preparation thereof
AT00949829T ATE241983T1 (en) 1999-07-28 2000-07-28 COMPOSITION CONTAINING PARACETAMOL AND DROTAVERINE
MEP-2008-185A ME00088B (en) 1999-07-28 2000-07-28 PHARMACEUTICAL COMPOSITION AND PREPARATION THEREOF

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9902559A HU225779B1 (en) 1999-07-28 1999-07-28 Pharmaceutical composition containing paracetamol and drotaverine and process for producing it
HUP9902559 1999-07-28

Publications (2)

Publication Number Publication Date
WO2001007024A2 WO2001007024A2 (en) 2001-02-01
WO2001007024A3 true WO2001007024A3 (en) 2001-03-29

Family

ID=90014235

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/HU2000/000086 Ceased WO2001007024A2 (en) 1999-07-28 2000-07-28 Paracetamol and drotaverine containing composition

Country Status (19)

Country Link
EP (1) EP1200088B1 (en)
AT (1) ATE241983T1 (en)
AU (1) AU6308800A (en)
BG (1) BG65553B1 (en)
DE (1) DE60003188T2 (en)
DK (1) DK1200088T3 (en)
EA (1) EA003779B1 (en)
EE (1) EE04952B1 (en)
ES (1) ES2197107T3 (en)
GE (1) GEP20053581B (en)
HR (1) HRP20020071B1 (en)
HU (1) HU225779B1 (en)
ME (2) ME00088B (en)
PL (1) PL197749B1 (en)
PT (1) PT1200088E (en)
RS (1) RS50074B (en)
SI (1) SI1200088T1 (en)
UA (1) UA72535C2 (en)
WO (1) WO2001007024A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2232018C2 (en) * 2002-10-09 2004-07-10 Открытое акционерное общество "Ирбитский химико-фармацевтический завод" Spasmolytic medicinal agent
RU2252024C2 (en) * 2003-04-22 2005-05-20 Гаврилов Андрей Станиславович Method for obtaining spasmolytic medicinal preparation
UY29527A1 (en) 2005-05-13 2006-12-29 Schering Ag PHARMACCUTIC COMPOSITION CONTAINING GESTRGENS AND / OR ESTRNGENS AND 5-METHYL - (6S) - TETRHYDROPHOLATE.
RU2704613C2 (en) * 2014-11-11 2019-10-30 Д-Р Редди'С Лабораторис Лимитед Pharmaceutical preparations with fixed combination of analgesic and antispasmodic agents doses
EP3520781A1 (en) * 2018-02-05 2019-08-07 Adamed sp. z o.o. A pharmaceutical composition comprising metamizole, drotaverine, and caffeine
CN115279346A (en) * 2020-03-09 2022-11-01 苏什玛·保罗·伯利亚 Controlled release formulation comprising drotaverine or its salts
CN115397411B (en) * 2020-04-23 2025-08-22 浙江养生堂天然药物研究所有限公司 Drug combinations and their uses
BG113694A (en) 2023-04-26 2024-10-31 "Адифарм" Еад Pharmaceutical composition in tablet form containing metamizole, caffeine and drotaverine and method of its preparation
PL451289A1 (en) * 2025-02-25 2026-04-13 Pikralida Spółka Z Ograniczoną Odpowiedzialnością Pharmaceutical composition containing naproxen and drotaverine or pharmaceutically acceptable salts thereof, method of its preparation, and its use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073379A (en) * 1988-09-07 1991-12-17 Basf Aktiengesellschaft Continuous preparation of solid pharmaceutical forms

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348745A (en) * 1989-05-09 1994-09-20 Miles Inc. Aqueous granulation solution and a method of tablet granulation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073379A (en) * 1988-09-07 1991-12-17 Basf Aktiengesellschaft Continuous preparation of solid pharmaceutical forms

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WOJCICKI, JERZY ET AL: "Effect of papaverine and atropine on pharmacokinetics of paracetamol administered orally", POL. J. PHARMACOL. PHARM. (1979), 31(3), 239-43, XP000974559 *

Also Published As

Publication number Publication date
DE60003188T2 (en) 2004-07-01
PT1200088E (en) 2003-10-31
HUP9902559A2 (en) 2002-04-29
DK1200088T3 (en) 2003-09-22
PL353209A1 (en) 2003-11-03
ME00088B (en) 2010-10-10
MEP18508A (en) 2010-06-10
HU225779B1 (en) 2007-08-28
EA200200211A1 (en) 2002-08-29
HRP20020071A2 (en) 2003-12-31
UA72535C2 (en) 2005-03-15
SI1200088T1 (en) 2003-12-31
BG106368A (en) 2002-08-30
EE200200042A (en) 2003-04-15
EE04952B1 (en) 2008-02-15
EP1200088B1 (en) 2003-06-04
YU6102A (en) 2005-03-15
DE60003188D1 (en) 2003-07-10
GEP20053581B (en) 2005-07-25
EP1200088A2 (en) 2002-05-02
HUP9902559D0 (en) 1999-10-28
HRP20020071B1 (en) 2011-01-31
BG65553B1 (en) 2008-12-30
HUP9902559A3 (en) 2003-05-28
ES2197107T3 (en) 2004-01-01
WO2001007024A2 (en) 2001-02-01
EA003779B1 (en) 2003-08-28
PL197749B1 (en) 2008-04-30
AU6308800A (en) 2001-02-13
RS50074B (en) 2009-01-22
ATE241983T1 (en) 2003-06-15

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