WO2001013944A3 - Stress-proteins from extra-cellular pathogens as vaccines against infectious agents - Google Patents

Stress-proteins from extra-cellular pathogens as vaccines against infectious agents Download PDF

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Publication number
WO2001013944A3
WO2001013944A3 PCT/GB2000/003228 GB0003228W WO0113944A3 WO 2001013944 A3 WO2001013944 A3 WO 2001013944A3 GB 0003228 W GB0003228 W GB 0003228W WO 0113944 A3 WO0113944 A3 WO 0113944A3
Authority
WO
WIPO (PCT)
Prior art keywords
proteins
extra
stress
infectious agents
vaccines against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2000/003228
Other languages
French (fr)
Other versions
WO2001013944A2 (en
Inventor
Camilo Anthony Leo Selw Colaco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunobiology Ltd
Original Assignee
Immunobiology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE60043390T priority Critical patent/DE60043390D1/en
Application filed by Immunobiology Ltd filed Critical Immunobiology Ltd
Priority to JP2001518080A priority patent/JP2003507431A/en
Priority to AT00954741T priority patent/ATE449610T1/en
Priority to EP00954741A priority patent/EP1204422B1/en
Priority to AU67099/00A priority patent/AU6709900A/en
Priority to DK00954741.5T priority patent/DK1204422T3/en
Priority to IL14815300A priority patent/IL148153A0/en
Priority to CA2382336A priority patent/CA2382336C/en
Publication of WO2001013944A2 publication Critical patent/WO2001013944A2/en
Publication of WO2001013944A3 publication Critical patent/WO2001013944A3/en
Priority to IL148153A priority patent/IL148153A/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6043—Heat shock proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to a method for producing and isolating specific immunogenic endogenous heat shock proteins induced by the treatment of extra-cellular pathogens with stress inducing stimuli and vaccines prepared from such proteins.
PCT/GB2000/003228 1999-08-19 2000-08-18 Stress-proteins from extra-cellular pathogens as vaccines against infectious agents Ceased WO2001013944A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CA2382336A CA2382336C (en) 1999-08-19 2000-08-18 Vaccines from infectious agents
JP2001518080A JP2003507431A (en) 1999-08-19 2000-08-18 Vaccines from infectious agents
AT00954741T ATE449610T1 (en) 1999-08-19 2000-08-18 STRESS PROTEINS OF EXTRACELLULAR PATHOGENS AS VACCINES AGAINST INFECTIOUS PATHOGENS
EP00954741A EP1204422B1 (en) 1999-08-19 2000-08-18 Stress-proteins from extra-cellular pathogens as vaccines against infectious agents
AU67099/00A AU6709900A (en) 1999-08-19 2000-08-18 Vaccines from infectious agents
DE60043390T DE60043390D1 (en) 1999-08-19 2000-08-18 STRESS PROTEINS EXTRACELLULAR PATHOGENS AS VACCINES AGAINST INFECTIOUS INFECTION
IL14815300A IL148153A0 (en) 1999-08-19 2000-08-18 Vaccines from infectious agents
DK00954741.5T DK1204422T3 (en) 1999-08-19 2000-08-18 Stress proteins from extra-cellular pathogens such as vaccines against disease-causing organisms
IL148153A IL148153A (en) 1999-08-19 2002-02-14 Method for producing a vaccine containing stress-proteins and vaccine produced by said method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9919734.5A GB9919734D0 (en) 1999-08-19 1999-08-19 Vaccines from infectious agents
GB9919734.5 1999-08-19

Publications (2)

Publication Number Publication Date
WO2001013944A2 WO2001013944A2 (en) 2001-03-01
WO2001013944A3 true WO2001013944A3 (en) 2001-09-20

Family

ID=10859501

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/003228 Ceased WO2001013944A2 (en) 1999-08-19 2000-08-18 Stress-proteins from extra-cellular pathogens as vaccines against infectious agents

Country Status (14)

Country Link
EP (1) EP1204422B1 (en)
JP (1) JP2003507431A (en)
CN (1) CN100523192C (en)
AT (1) ATE449610T1 (en)
AU (1) AU6709900A (en)
CA (1) CA2382336C (en)
DE (1) DE60043390D1 (en)
DK (1) DK1204422T3 (en)
ES (1) ES2336417T3 (en)
GB (1) GB9919734D0 (en)
IL (2) IL148153A0 (en)
PT (1) PT1204422E (en)
WO (1) WO2001013944A2 (en)
ZA (1) ZA200201359B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0004547D0 (en) * 2000-02-23 2000-04-19 Immunobiology Ltd Screening method for novel vaccine candidates and compositions obtained thereby
GB0021757D0 (en) * 2000-09-04 2000-10-18 Colaco Camilo Vaccine against microbial pathogens
WO2009021291A1 (en) * 2007-08-16 2009-02-19 The University Of Sydney Mycobacterium vaccine formulation
GB0910591D0 (en) 2009-06-19 2009-07-29 Immunobiology Ltd Method for the purification of protein complexes
GB0916557D0 (en) 2009-09-21 2009-10-28 Health Prot Agency Commensal neisserial stress protein complexes
GB201104897D0 (en) 2011-03-23 2011-05-04 Immunobiology Ltd Method for the production of protein complexes and vaccine compositions comprising the same
CN110240636A (en) * 2019-06-04 2019-09-17 华中农业大学 Mycobacterium bovis molecular chaperone protein GroEL1 and its encoding gene and application

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990002564A1 (en) * 1988-09-12 1990-03-22 Codon Vaccine diagnostic employing proteins homologous to heat shock proteins of trypanosoma cruzi
WO1996040928A1 (en) * 1995-06-07 1996-12-19 Biochem Vaccines Inc. Streptococcal heat shock proteins members of the hsp70 family

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5961979A (en) * 1994-03-16 1999-10-05 Mount Sinai School Of Medicine Of The City University Of New York Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990002564A1 (en) * 1988-09-12 1990-03-22 Codon Vaccine diagnostic employing proteins homologous to heat shock proteins of trypanosoma cruzi
WO1996040928A1 (en) * 1995-06-07 1996-12-19 Biochem Vaccines Inc. Streptococcal heat shock proteins members of the hsp70 family

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FERRERO RICHARD L ET AL: "The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 92, no. 14, 1995, 1995, pages 6499 - 6503, XP002160650, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
IL148153A (en) 2011-04-28
CN100523192C (en) 2009-08-05
AU6709900A (en) 2001-03-19
JP2003507431A (en) 2003-02-25
ATE449610T1 (en) 2009-12-15
EP1204422A2 (en) 2002-05-15
CA2382336A1 (en) 2001-03-01
IL148153A0 (en) 2002-09-12
ZA200201359B (en) 2003-07-30
CN1556856A (en) 2004-12-22
EP1204422B1 (en) 2009-11-25
WO2001013944A2 (en) 2001-03-01
DE60043390D1 (en) 2010-01-07
ES2336417T3 (en) 2010-04-13
DK1204422T3 (en) 2010-03-15
GB9919734D0 (en) 1999-10-20
PT1204422E (en) 2010-02-05
CA2382336C (en) 2012-07-10

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