WO2001038317A3 - Fungicidal melithiazole derivatives - Google Patents

Fungicidal melithiazole derivatives Download PDF

Info

Publication number
WO2001038317A3
WO2001038317A3 PCT/EP2000/011643 EP0011643W WO0138317A3 WO 2001038317 A3 WO2001038317 A3 WO 2001038317A3 EP 0011643 W EP0011643 W EP 0011643W WO 0138317 A3 WO0138317 A3 WO 0138317A3
Authority
WO
WIPO (PCT)
Prior art keywords
group
alkyl group
melithiazole
fungicidal
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2000/011643
Other languages
French (fr)
Other versions
WO2001038317A2 (en
Inventor
Oliver Meyer
Werner Simon
Gerhard Hoefle
Udo Soeker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
BASF SE
BASF Corp
Original Assignee
Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
BASF SE
BASF Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helmholtz Zentrum fuer Infektionsforschung HZI GmbH, BASF SE, BASF Corp filed Critical Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
Priority to AU25082/01A priority Critical patent/AU2508201A/en
Priority to EP00988747A priority patent/EP1232149A2/en
Publication of WO2001038317A2 publication Critical patent/WO2001038317A2/en
Publication of WO2001038317A3 publication Critical patent/WO2001038317A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
    • A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compounds with contain essentially equimolar amounts of the enantiomer pair of formulae (IA and IB), wherein R1 represents a hydrogen atom or an optionally substituted alkyl, alkenyl, or aryl group; R?2, R3, R4 and R5¿ each independently represent an alkyl group; and R6 represents a group of formula -COOR7 or -CONR7R8, in which R?7 and R8¿ each independently represent a hydrogen atom or an alkyl group; L1 represents a hydrogen or halogen atom or an optionally substituted alkyl group; and wherein th ezigzag line indicates that the alkoximino group may have the (E)- or (Z)-configuration show excellent fungicidal activity and systemicity.
PCT/EP2000/011643 1999-11-24 2000-11-23 Fungicidal melithiazole derivatives Ceased WO2001038317A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU25082/01A AU2508201A (en) 1999-11-24 2000-11-23 Fungicidal melithiazole derivatives
EP00988747A EP1232149A2 (en) 1999-11-24 2000-11-23 Fungicidal melithiazole derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44914399A 1999-11-24 1999-11-24
US09/449,143 1999-11-24

Publications (2)

Publication Number Publication Date
WO2001038317A2 WO2001038317A2 (en) 2001-05-31
WO2001038317A3 true WO2001038317A3 (en) 2001-11-08

Family

ID=23783037

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/011643 Ceased WO2001038317A2 (en) 1999-11-24 2000-11-23 Fungicidal melithiazole derivatives

Country Status (3)

Country Link
EP (1) EP1232149A2 (en)
AU (1) AU2508201A (en)
WO (1) WO2001038317A2 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5360811A (en) * 1990-03-13 1994-11-01 Hoechst-Roussel Pharmaceuticals Incorporated 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds as anti-inflammatory agents
DE4410449A1 (en) * 1994-03-25 1995-09-28 Biotechnolog Forschung Gmbh Melithiazoles, method of preparation, compositions containing melithiazole and melittangium lichenicola DSM 9004 with the ability to form melithiazoles
WO1998025929A1 (en) * 1996-12-13 1998-06-18 Novartis Ag Epothilone analogs
WO1998046583A1 (en) * 1997-04-11 1998-10-22 Gesellschaft Für Biotechnologische Forschung, Mbh Fungicidal melithiazole derivatives
WO1999003848A1 (en) * 1997-07-16 1999-01-28 Schering Aktiengesellschaft Thiazole derivatives, method for their production and use
WO1999067252A2 (en) * 1998-06-22 1999-12-29 Novartis Ag Epothilone derivatives and their synthesis and use

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5360811A (en) * 1990-03-13 1994-11-01 Hoechst-Roussel Pharmaceuticals Incorporated 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds as anti-inflammatory agents
DE4410449A1 (en) * 1994-03-25 1995-09-28 Biotechnolog Forschung Gmbh Melithiazoles, method of preparation, compositions containing melithiazole and melittangium lichenicola DSM 9004 with the ability to form melithiazoles
WO1998025929A1 (en) * 1996-12-13 1998-06-18 Novartis Ag Epothilone analogs
WO1998046583A1 (en) * 1997-04-11 1998-10-22 Gesellschaft Für Biotechnologische Forschung, Mbh Fungicidal melithiazole derivatives
WO1999003848A1 (en) * 1997-07-16 1999-01-28 Schering Aktiengesellschaft Thiazole derivatives, method for their production and use
WO1999067252A2 (en) * 1998-06-22 1999-12-29 Novartis Ag Epothilone derivatives and their synthesis and use

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BRUCE J MARTIN ET AL: "Total Synthesis of the beta-Methoxyacrylate-based Fungicide Myxothiazol", TETRAHEDRON LETTERS,ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM,NL, vol. 34, no. 32, 6 August 1993 (1993-08-06), pages 5151 - 5154, XP002151787, ISSN: 0040-4039 *
SCHUMMER ET AL: "An improved preparation of tris(ethylenedioxyboryl)methane, a reagent for the homologation of aldehydes and ketones", TETRAHEDRON,NL,ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, vol. 51, no. 41, 1995, pages 11219 - 11222, XP002121566, ISSN: 0040-4020 *
T ROSS KELLY ET AL: "SYNTHESIS OF MICROCOCCINIC ACID", TETRAHEDRON LETTERS, vol. 32, no. 34, 1991, pages 4263 - 6, XP002166496 *

Also Published As

Publication number Publication date
EP1232149A2 (en) 2002-08-21
WO2001038317A2 (en) 2001-05-31
AU2508201A (en) 2001-06-04

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