WO2001049741A3 - A process for isolation of osteopontin from milk - Google Patents

A process for isolation of osteopontin from milk Download PDF

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Publication number
WO2001049741A3
WO2001049741A3 PCT/DK2001/000005 DK0100005W WO0149741A3 WO 2001049741 A3 WO2001049741 A3 WO 2001049741A3 DK 0100005 W DK0100005 W DK 0100005W WO 0149741 A3 WO0149741 A3 WO 0149741A3
Authority
WO
WIPO (PCT)
Prior art keywords
milk
osteopontin
isolation
rest
adjustment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DK2001/000005
Other languages
French (fr)
Other versions
WO2001049741A2 (en
Inventor
Esben Skipper Soerensen
Steen Ostersen
Dereck Chatterton
Hans Henrik Holst
Kristian Albertsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arla Foods AMBA
Original Assignee
Arla Foods AMBA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA2396519A priority Critical patent/CA2396519C/en
Application filed by Arla Foods AMBA filed Critical Arla Foods AMBA
Priority to US10/168,303 priority patent/US7259243B2/en
Priority to EP01900100A priority patent/EP1244702B1/en
Priority to DK01900100T priority patent/DK1244702T3/en
Priority to AU23528/01A priority patent/AU784322B2/en
Priority to JP2001550281A priority patent/JP4615173B2/en
Priority to DE60119077T priority patent/DE60119077T2/en
Priority to NZ519492A priority patent/NZ519492A/en
Publication of WO2001049741A2 publication Critical patent/WO2001049741A2/en
Publication of WO2001049741A3 publication Critical patent/WO2001049741A3/en
Priority to NO20023057A priority patent/NO330264B1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Feed For Specific Animals (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

A process for isolation of milk osteopontin from a material containing milk osteopontin by optionally mixing the milk material with a calcium source and separate the osteopontin containing phase from the rest of the milk material by pH adjustment.
PCT/DK2001/000005 2000-01-07 2001-01-04 A process for isolation of osteopontin from milk Ceased WO2001049741A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
NZ519492A NZ519492A (en) 2000-01-07 2001-01-04 A process for isolation of osteopontin from milk
US10/168,303 US7259243B2 (en) 2000-01-07 2001-01-04 Process for isolation of osteopontin from milk
EP01900100A EP1244702B1 (en) 2000-01-07 2001-01-04 Process for isolation of osteopontin from milk
DK01900100T DK1244702T3 (en) 2000-01-07 2001-01-04 Method for extracting osteopontin from milk
AU23528/01A AU784322B2 (en) 2000-01-07 2001-01-04 A process for isolation of osteopontin from milk
CA2396519A CA2396519C (en) 2000-01-07 2001-01-04 A process for isolation of osteopontin from milk
DE60119077T DE60119077T2 (en) 2000-01-07 2001-01-04 METHOD OF ISOLATING OSTEOPONTIN FROM MILK
JP2001550281A JP4615173B2 (en) 2000-01-07 2001-01-04 Method for the isolation of osteopontin from milk
NO20023057A NO330264B1 (en) 2000-01-07 2002-06-24 A method for isolating osteopontin from milk

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000013 2000-01-07
DKPA200000013 2000-01-07

Publications (2)

Publication Number Publication Date
WO2001049741A2 WO2001049741A2 (en) 2001-07-12
WO2001049741A3 true WO2001049741A3 (en) 2002-01-17

Family

ID=8158885

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2001/000005 Ceased WO2001049741A2 (en) 2000-01-07 2001-01-04 A process for isolation of osteopontin from milk

Country Status (16)

Country Link
US (1) US7259243B2 (en)
EP (1) EP1244702B1 (en)
JP (1) JP4615173B2 (en)
KR (1) KR100733538B1 (en)
AR (1) AR027507A1 (en)
AT (1) ATE324378T1 (en)
AU (1) AU784322B2 (en)
CA (1) CA2396519C (en)
DE (1) DE60119077T2 (en)
DK (1) DK1244702T3 (en)
ES (1) ES2258520T3 (en)
NO (1) NO330264B1 (en)
NZ (1) NZ519492A (en)
PT (1) PT1244702E (en)
RU (1) RU2264734C2 (en)
WO (1) WO2001049741A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103492408B (en) * 2011-03-03 2015-07-29 阿拉食品公司 Process for isolating osteopontin using feedstock comprising CMP or casein species

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ507335A (en) * 2000-10-05 2004-10-29 New Zealand Dairy Board Bone health compositions derived from milk comprising an acidic protein fraction but that does not contain CGMP
GB0227886D0 (en) * 2002-11-29 2003-01-08 Medical Res Council Prion inhibition
CN1852665B (en) * 2003-09-18 2010-09-01 阿尔拉食品公司 infant formula
JP4509114B2 (en) * 2003-09-18 2010-07-21 アルラ・フーズ・エイ・エム・ビィ・エイ Infant formula
EP1625877A3 (en) * 2004-08-09 2006-03-08 Friesland Brands B.V. Functional milk fraction
PT1968996E (en) * 2005-12-06 2009-11-17 Vifor Int Ag Process for the preparation of ferri-succinylcasein
FR2901796A1 (en) * 2006-05-31 2007-12-07 Lab Francais Du Fractionnement PROCESS FOR EXTRACTING ONE OR MORE PROTEINS PRESENT IN MILK
WO2009027284A1 (en) * 2007-08-31 2009-03-05 Laboratoires Serono Sa Purification of osteopontin
US9783996B2 (en) 2007-11-19 2017-10-10 Valinge Innovation Ab Fibre based panels with a wear resistance surface
GB0813015D0 (en) * 2008-07-16 2008-08-20 Plant Bioscience Ltd Phosphoproteins and use of the same
EP2788015A1 (en) 2011-12-07 2014-10-15 Arla Foods Amba Osteopontin variants for use in suppression or prevention of tumor growth and compositions containing such osteopontin variants
EA201491691A1 (en) 2012-03-28 2015-04-30 Арла Фудз Амба UNITS OF NANOPARTICLES CONTAINING OSTEOPONTIN AND CALCIUM AND / OR STRONTIUM PARTY
ES2656474T3 (en) 2013-07-05 2018-02-27 Arla Foods Amba Osteopontin of mammalian origin to enhance immune response capacity
EP3538053B1 (en) 2016-11-08 2026-04-15 Dentherapy Ltd Compositions comprising fluoride and calcium and method for preparing them
WO2018098001A1 (en) * 2016-11-27 2018-05-31 Triton Algae Innovations, Inc. Method of purification of recombinant osteopontin from microalgae
GB202010987D0 (en) 2020-07-16 2020-09-02 Dentherapy Ltd Oral care compositions and methods
EP4326076A1 (en) * 2021-04-19 2024-02-28 Société des Produits Nestlé S.A. Use of milk protein fractions as a source of osteopontin
GB202110114D0 (en) 2021-07-14 2021-08-25 Dentherapy Ltd Oral care compositions for use in treaatment
EP4373287A2 (en) 2021-07-20 2024-05-29 Arla Foods amba Method of preparing a whey-derived composition enriched in phospholipids and osteopontin, the composition as such, and nutritional use of the composition
CN115073580B (en) * 2022-06-22 2026-03-10 黑龙江飞鹤乳业有限公司 Osteopontin separation method
EP4587455A1 (en) 2022-09-16 2025-07-23 Univerza V Ljubljani Isolation of osteopontin and glycomacropeptide from whey
WO2025008636A1 (en) 2023-07-06 2025-01-09 Dentherapy Ltd Oral care compositions for use in the treatment of dental health conditions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0404425A1 (en) * 1989-06-20 1990-12-27 The Calpis Food Industry Co., Ltd. Method for the preparation of a substance capable of proliferating bifidobacteria growth
US5216129A (en) * 1990-04-27 1993-06-01 Nestec S.A. Production of kappa-caseino-glycomacropeptide

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0404425A1 (en) * 1989-06-20 1990-12-27 The Calpis Food Industry Co., Ltd. Method for the preparation of a substance capable of proliferating bifidobacteria growth
US5216129A (en) * 1990-04-27 1993-06-01 Nestec S.A. Production of kappa-caseino-glycomacropeptide

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1997, BAYLESS KAYLA J ET AL: "Isolation and biological properties of osteopontin from bovine milk.", XP002146905, Database accession no. PREV199799513298 *
JU ZHI YONG ET AL: "Gelation of pH-aggregated whey protein isolate solution induced by heat, protease, calcium salt, and acidulant.", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 46, no. 5, May 1998 (1998-05-01), pages 1830 - 1835, XP002146903, ISSN: 0021-8561 *
PROTEIN EXPRESSION AND PURIFICATION, vol. 9, no. 3, 1997, pages 309 - 314, ISSN: 1046-5928 *
SALIH ERDJAN ET AL: "Identification of the phosphorylated sites of metabolically 32P-labeled osteopontin from cultured chicken osteoblasts.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 21, 1997, pages 13966 - 13973, XP002146966, ISSN: 0021-9258 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103492408B (en) * 2011-03-03 2015-07-29 阿拉食品公司 Process for isolating osteopontin using feedstock comprising CMP or casein species

Also Published As

Publication number Publication date
EP1244702A2 (en) 2002-10-02
ES2258520T3 (en) 2006-09-01
US7259243B2 (en) 2007-08-21
DE60119077D1 (en) 2006-06-01
AU784322B2 (en) 2006-03-09
NZ519492A (en) 2003-03-28
DE60119077T2 (en) 2006-09-07
NO20023057L (en) 2002-06-24
CA2396519C (en) 2011-03-22
JP4615173B2 (en) 2011-01-19
RU2002118313A (en) 2004-02-20
ATE324378T1 (en) 2006-05-15
PT1244702E (en) 2006-08-31
AU2352801A (en) 2001-07-16
KR20020073159A (en) 2002-09-19
WO2001049741A2 (en) 2001-07-12
DK1244702T3 (en) 2006-08-28
JP2003519239A (en) 2003-06-17
NO20023057D0 (en) 2002-06-24
NO330264B1 (en) 2011-03-14
AR027507A1 (en) 2003-04-02
RU2264734C2 (en) 2005-11-27
EP1244702B1 (en) 2006-04-26
US20030149249A1 (en) 2003-08-07
CA2396519A1 (en) 2001-07-12
KR100733538B1 (en) 2007-06-28

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