WO2001057190A3 - Novel nucleic acids and polypeptides - Google Patents

Novel nucleic acids and polypeptides Download PDF

Info

Publication number
WO2001057190A3
WO2001057190A3 PCT/US2001/004098 US0104098W WO0157190A3 WO 2001057190 A3 WO2001057190 A3 WO 2001057190A3 US 0104098 W US0104098 W US 0104098W WO 0157190 A3 WO0157190 A3 WO 0157190A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
polypeptides
novel nucleic
novel
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/004098
Other languages
French (fr)
Other versions
WO2001057190A2 (en
Inventor
Y Tom Tang
Chenghua Liu
Radoje T Drmanac
Vinod Asundi
Ping Zhou
Chongjun Xu
Yicheng Cao
Yunquing Ma
Qing A Zhao
Dunrui Wang
Jian-Rui Wang
Jie Zhang
Feiyan Ren
Rui-Hong Chen
Zhi Wei Wang
Aidong J Xue
Yonghong Yang
Tom Wejhrman
Ryle Goodrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hyseq Inc
Original Assignee
Hyseq Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/728,422 external-priority patent/US20020128187A1/en
Application filed by Hyseq Inc filed Critical Hyseq Inc
Priority to EP01907128A priority Critical patent/EP1572987A4/en
Priority to AU2001234944A priority patent/AU2001234944A1/en
Priority to CA002399776A priority patent/CA2399776A1/en
Publication of WO2001057190A2 publication Critical patent/WO2001057190A2/en
Anticipated expiration legal-status Critical
Priority to US10/627,373 priority patent/US20050164202A1/en
Priority to US11/218,141 priority patent/US20070042392A1/en
Publication of WO2001057190A3 publication Critical patent/WO2001057190A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6432—Coagulation factor Xa (3.4.21.6)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21006—Coagulation factor Xa (3.4.21.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
PCT/US2001/004098 2000-02-03 2001-02-05 Novel nucleic acids and polypeptides Ceased WO2001057190A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP01907128A EP1572987A4 (en) 2000-02-03 2001-02-05 Novel nucleic acids and polypeptides
AU2001234944A AU2001234944A1 (en) 2000-02-03 2001-02-05 Novel nucleic acids and polypeptides
CA002399776A CA2399776A1 (en) 2000-02-03 2001-02-05 Novel nucleic acids and polypeptides
US10/627,373 US20050164202A1 (en) 2000-02-03 2003-07-24 Materials and methods relating to therapy and diagnosis using targeting of cells that express JPL polypeptides
US11/218,141 US20070042392A1 (en) 2000-02-03 2005-08-31 Novel nucleic acids and polypeptides

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US49691400A 2000-02-03 2000-02-03
US09/496,914 2000-02-03
US56087500A 2000-04-27 2000-04-27
US09/560,875 2000-04-27
US59807500A 2000-06-20 2000-06-20
US09/598,075 2000-06-20
US62032500A 2000-07-19 2000-07-19
US09/620,325 2000-07-19
US65493600A 2000-09-01 2000-09-01
US09/654,936 2000-09-01
US66356100A 2000-09-15 2000-09-15
US09/663,561 2000-09-15
US69332500A 2000-10-20 2000-10-20
US09/693,325 2000-10-20
US09/728,422 2000-11-30
US09/728,422 US20020128187A1 (en) 2000-02-03 2000-11-30 Novel nucleic acids and polypeptides

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US65493600A Continuation-In-Part 2000-02-03 2000-09-01

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US10258899 A-371-Of-International 2001-02-05
US29324402A Continuation-In-Part 2000-02-03 2002-11-12
US11/218,141 Continuation-In-Part US20070042392A1 (en) 2000-02-03 2005-08-31 Novel nucleic acids and polypeptides

Publications (2)

Publication Number Publication Date
WO2001057190A2 WO2001057190A2 (en) 2001-08-09
WO2001057190A3 true WO2001057190A3 (en) 2006-11-16

Family

ID=27575454

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/004098 Ceased WO2001057190A2 (en) 2000-02-03 2001-02-05 Novel nucleic acids and polypeptides

Country Status (4)

Country Link
EP (1) EP1572987A4 (en)
AU (1) AU2001234944A1 (en)
CA (1) CA2399776A1 (en)
WO (1) WO2001057190A2 (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7259002B2 (en) 2003-01-21 2007-08-21 Bristol-Myers Squibb Company Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof
US7628989B2 (en) 2001-04-10 2009-12-08 Agensys, Inc. Methods of inducing an immune response
US8835387B2 (en) 2012-02-16 2014-09-16 Atyr Pharma, Inc. Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
US8958881B2 (en) 2005-08-19 2015-02-17 Brainsgate Ltd. Neuroprotective electrical stimulation
US9127268B2 (en) 2009-12-11 2015-09-08 Atyr Pharma, Inc. Aminoacyl tRNA synthetases for modulating inflammation
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
US9422539B2 (en) 2010-07-12 2016-08-23 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-tRNA synthetases
US9587235B2 (en) 2013-03-15 2017-03-07 Atyr Pharma, Inc. Histidyl-tRNA synthetase-Fc conjugates
US9593167B2 (en) 2006-10-27 2017-03-14 Genentech, Inc. Antibodies and immunoconjugates and uses therefor
US9617346B2 (en) 2004-04-22 2017-04-11 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
US10663455B2 (en) 2009-09-16 2020-05-26 Active Motif, Inc. Transcription biomarkers of biological responses and methods of use
US11180571B2 (en) 2017-04-03 2021-11-23 Hoffmann-La Roche Inc. Antibodies binding to STEAP-1

Families Citing this family (156)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7057017B2 (en) 1997-04-16 2006-06-06 Millennium Pharmaceuticals, Inc. Human dickkopf-related protein and nucleic acid molecules and uses therefor
US20030068623A1 (en) 1997-06-16 2003-04-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7446181B2 (en) 1998-01-15 2008-11-04 Millennium Pharmaceuticals, Inc. Antibodies that bind human Dickkopf-1 proteins
EP1086223B1 (en) 1998-06-01 2009-07-29 Agensys, Inc. Novel serpentine transmembrane antigens expressed in human cancers and uses thereof
US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US6833438B1 (en) 1999-06-01 2004-12-21 Agensys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US7264801B2 (en) 1998-08-11 2007-09-04 Genentech, Inc. EG-VEGF nucleic acids and polypeptides and method of use
US20020172678A1 (en) 2000-06-23 2002-11-21 Napoleone Ferrara EG-VEGF nucleic acids and polypeptides and methods of use
US20030003507A1 (en) 1999-06-02 2003-01-02 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6344541B1 (en) 1998-09-25 2002-02-05 Amgen Inc. DKR polypeptides
JP2002534112A (en) 1999-01-15 2002-10-15 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド Bone marrow specific protein
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
JP2004522402A (en) * 1999-06-02 2004-07-29 ジェネンテック・インコーポレーテッド Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20030204052A1 (en) * 2000-10-04 2003-10-30 Herrmann John L. Novel proteins and nucleic acids encoding same and antibodies directed against these proteins
AU776341B2 (en) * 1999-08-19 2004-09-02 Kurokawa, Kiyoshi Meg-1 protein
US7790861B2 (en) * 1999-09-24 2010-09-07 Philadelphia Health And Education Corporation Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
US20020042062A1 (en) 1999-09-24 2002-04-11 Mark Stearns Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
CA2389724A1 (en) * 1999-11-12 2001-05-17 Human Genome Sciences, Inc. 28 human secreted proteins
CA2395416A1 (en) 1999-12-23 2001-06-28 Millennium Pharmaceuticals, Inc. P2y12 receptor
WO2001059079A1 (en) 2000-02-11 2001-08-16 Glycozym Aps UDP-GALACTOSE: β-D-GALACTOSE-R 4-α-D-GALACTOSYLTRANSFERASE, α4GAL-T1
JP4342069B2 (en) * 2000-02-14 2009-10-14 生化学工業株式会社 α1,4-Galactosyltransferase and DNA encoding the same
AU6802801A (en) * 2000-03-01 2001-09-24 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1698697A3 (en) * 2000-03-24 2006-09-13 Takeda Pharmaceutical Company Limited SSD-containing protein, process for producing the same and use thereof
US20020065223A1 (en) * 2000-06-16 2002-05-30 Glucksmann Maria Alexandra 33358, a novel human ankyrin family member and uses thereof
CA2405104A1 (en) * 2000-04-05 2001-10-18 Kirin Beer Kabushiki Kaisha Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
AU2001268967A1 (en) * 2000-04-18 2001-10-30 Bayer Aktiengesellschaft Regulation of human epithin-like serine protease
AU2001257407A1 (en) * 2000-04-26 2001-11-07 Millennium Pharmaceuticals, Inc. 21657, a human short-chain dehydrogenase and uses thereof
US20030092035A1 (en) 2000-05-04 2003-05-15 Anderson David J. Pain signaling molecules
US7510845B2 (en) 2000-05-04 2009-03-31 California Institute Of Technology Assay employing G protein-coupled receptor expressed in dorsal root ganglia
US7117033B2 (en) 2000-05-08 2006-10-03 Brainsgate, Ltd. Stimulation for acute conditions
WO2001085935A2 (en) * 2000-05-09 2001-11-15 Bayer Aktiengesellschaft Endothelial differentiation gene 6-like g protein coupled receptor
WO2001092494A2 (en) * 2000-05-26 2001-12-06 Millennium Pharmaceuticals, Inc. 50250, a human lipase and uses thereof
AU2001272974A1 (en) * 2000-06-21 2002-01-02 Incyte Genomics, Inc. Human receptors
AU7018801A (en) * 2000-06-26 2002-01-08 Millennium Pharm Inc 46619, a novel human beta-ketoacyl synthase and uses thereof
WO2002002599A2 (en) * 2000-06-30 2002-01-10 Ingenium Pharmaceuticals Ag HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR17, AND USES THEROF
WO2002006312A2 (en) * 2000-07-13 2002-01-24 Novartis Ag Disease-associated gene
AU2001278488A1 (en) * 2000-07-25 2002-02-05 Bayer Aktiengesellschaft Regulation of human matriptase-like serine protease
EP1315431A1 (en) * 2000-08-02 2003-06-04 Millennium Pharmaceuticals, Inc. A human gtp-releasing factor family member (15368) and uses therefor
JP2004527210A (en) 2000-08-02 2004-09-09 ザ ジョンズ ホプキンス ユニバーシティー Evaluation method of endothelial cell expression pattern
US20040053262A1 (en) * 2000-08-04 2004-03-18 Xin Lu Supressor gene
AU2001295454A1 (en) * 2000-08-14 2002-02-25 Bayer Aktiengesellschaft Regulation of human p2y1-like g protein-coupled receptor
EP1688496A3 (en) * 2000-08-14 2006-08-16 Actimis Pharmaceuticals, Inc., Regulation of human P2Y1-like G protein-coupled receptor
AU2001284902A1 (en) * 2000-08-15 2002-02-25 Zymogenetics Inc. Human adenosine deaminase
US6706513B2 (en) 2000-08-21 2004-03-16 Bristol-Myers Squibb Company Adenosine deaminase homolog
US20030224396A1 (en) * 2000-08-30 2003-12-04 Yonghong Xiao Regulation of human aminotransferase-like enzyme
US20030166300A1 (en) * 2000-08-30 2003-09-04 Tang Y. Tom Growth-related inflammatory and immune response protein
US20040072185A1 (en) * 2000-09-15 2004-04-15 Patrizia Paterlini-Brechot Cellular genes involved in oncogenesis, products of said genes and their diagnostic and therapeutic uses
US7754435B2 (en) * 2000-09-21 2010-07-13 Philadelphia Health And Education Corporation Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
AU2002220613A1 (en) * 2000-10-11 2002-04-22 Bayer Aktiengesellschaft Regulation of human cyclophilin-type peptidyl-prolyl cis-trans isomerase
AU2001297794A1 (en) 2000-10-19 2002-12-03 Millenium Pharmaceuticals, Inc. Methods and compositions of human proteins and uses thereof.
JP2004532609A (en) 2000-11-03 2004-10-28 ザ リージェント オブ ザ ユニバーシティ オブ カリフォルニア Prokineticin polypeptides, related compositions and methods
EP1364012A2 (en) * 2000-11-08 2003-11-26 Millennium Pharmaceuticals, Inc. 38650, 28472, 5495, 65507, 81588 and 14354 methods and compositions of human proteins and uses thereof
WO2002038743A2 (en) * 2000-11-09 2002-05-16 Glaxo Group Limited Deaminase catalyzing the removal of the cyclopropyl moiety from abacavir-mp
IL155800A0 (en) * 2000-11-09 2003-12-23 Univ Virginia Nucleic acid sequences encoding human testis specific kinases
US7312086B2 (en) 2000-12-07 2007-12-25 Bristol-Myers Squibb Company Methods of diagnosing colon adenocarcinoma using the human g-protein coupled receptor hgprbmy23
EP1387888A2 (en) * 2000-12-21 2004-02-11 Incyte Genomics, Inc. Nucleic acid-associated proteins
US7892730B2 (en) * 2000-12-22 2011-02-22 Sagres Discovery, Inc. Compositions and methods for cancer
US20030148920A1 (en) * 2000-12-27 2003-08-07 Steven Rosen Sulfatases and methods of use thereof
WO2002053719A2 (en) * 2001-01-04 2002-07-11 Incyte Genomics, Inc. Cytoskeleton-associated proteins
US20040126759A1 (en) * 2001-01-05 2004-07-01 Baughn Mariah R. Molecules for disease detection and treatment
US6319679B1 (en) * 2001-01-26 2001-11-20 Board Of Regents, The University Of Texas System PAS kinase
US20020115136A1 (en) * 2001-02-07 2002-08-22 Gennady Merkulov Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002064777A2 (en) * 2001-02-14 2002-08-22 Axaron Bioscience Ag Proteins 7b6 and 11b4 and dna sequences encoding the same
AU2002258520A1 (en) * 2001-03-16 2002-10-03 Incyte Genomics, Inc. Nucleic acid-associated proteins
US20030044813A1 (en) * 2001-03-30 2003-03-06 Old Lloyd J. Cancer-testis antigens
US20020146795A1 (en) * 2001-04-02 2002-10-10 Shiaoping Zhu Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof
US7033790B2 (en) 2001-04-03 2006-04-25 Curagen Corporation Proteins and nucleic acids encoding same
US7927597B2 (en) * 2001-04-10 2011-04-19 Agensys, Inc. Methods to inhibit cell growth
US6962811B2 (en) 2001-05-09 2005-11-08 Millennium Pharmaceuticals, Inc. 14715, a human fringe family member nucleic acids and uses therefor
DE60237518D1 (en) 2001-05-29 2010-10-14 Human Cell Systems Inc TESTICULAR CARNITINE TRANSPORTER AND ITS GENE
DE60237917D1 (en) 2001-06-05 2010-11-18 Exelixis Inc GFATS AS MODULATORS OF THE P53 PATH AND METHOD OF USE
PT2000545E (en) * 2001-06-20 2011-12-21 Genentech Inc COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF PULMONARY TUMOR
AU2002319261A1 (en) * 2001-06-25 2003-01-08 Bayer Aktiengesellschaft Regulation of human serine/threonine protein kinase nek3
US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
EP2287186B1 (en) 2001-09-06 2014-12-31 Agensys, Inc. Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
WO2003029828A2 (en) * 2001-09-24 2003-04-10 Grünenthal GmbH Screening method for different indications using bnpi and/or dnpi
US7265214B2 (en) 2001-10-19 2007-09-04 Rigel Pharmaceuticals, Inc. Germinal center kinase proteins, compositions and methods of use
WO2003038040A2 (en) * 2001-10-29 2003-05-08 Millennium Pharmaceuticals, Inc. 32235, a human aminotransferase family member and uses therefor
EP1440169A4 (en) * 2001-10-31 2005-09-21 Millennium Pharm Inc Methods and compositions for the treatment and diagnosis of pain disorders using 57749
EP1439864A4 (en) 2001-10-31 2004-12-22 Millennium Pharm Inc Methods for the treatment and diagnosis of tumorigenic and angiogenic disorders using 32616
EP1310552B1 (en) 2001-11-09 2007-06-13 Proteologics, Inc. Posh nucleic acids, polypeptides and related methods
AU2002360460A1 (en) * 2001-12-03 2003-06-17 Nuvelo, Inc. Methods and materials relating to novel polypeptides and polynucleotides
DE60217711T2 (en) * 2001-12-04 2007-11-15 Develogen Aktiengesellschaft PTP10D NUCLEIC ACIDS AND PEPTIDES IN THE REGULATION OF ENERGY HOMEOSTASIS
WO2003054153A2 (en) * 2001-12-12 2003-07-03 University Of Cincinnati Apyrase polypeptides and nucleic acids encoding same
US7858297B2 (en) 2001-12-18 2010-12-28 Centre National De La Recherche Scientifique Cnrs Chemokine-binding protein and methods of use
CA2471777A1 (en) * 2001-12-18 2003-06-26 Endocube Sas Novel death associated proteins of the thap family and related par4 pathways involved in apoptosis control
AU2003244347A1 (en) * 2002-02-04 2003-09-02 Takeda Chemical Industries, Ltd. Angiogenesis inhibitors
GB0205112D0 (en) * 2002-03-05 2002-04-17 Pantherix Ltd Enzyme
JP4176022B2 (en) 2002-03-11 2008-11-05 独立行政法人科学技術振興機構 Practical chiral zirconium catalyst
DE10212397A1 (en) * 2002-03-20 2003-10-16 Universitaetsklinikum Freiburg Repressor of skeletal muscle differentiation, nucleic acid coding for it and its use in diagnostics and therapy
WO2003086462A1 (en) * 2002-03-29 2003-10-23 Celestar Lexico-Sciences,Inc. c-Jun PHOSPHORYLATION INHIBITORS
WO2003082342A1 (en) * 2002-04-01 2003-10-09 National Institute Of Advanced Industrial Science And Technology Application of kiaa0172 gene to treatment and diagnosis of diseases and drug discovery
WO2003091447A2 (en) 2002-04-26 2003-11-06 California Institute Of Technology D1-1 nucleic acids, polypeptides and related methods
US7622443B2 (en) 2002-04-26 2009-11-24 California Institute Of Technology Method for inhibiting pro-angiogenic activities of endothelial cells selectively at a site of neoangiogenesis in a mammal by administration of the extracellular domain of D1-1 polypeptides
DE10222845A1 (en) * 2002-05-23 2003-12-04 Dresden Arzneimittel Cloning, expression and characterization of the overall sequence of phosphodiesterase 8B
EP1572952B1 (en) * 2002-06-28 2010-09-29 Imclone LLC Novel polynucleotide and polypeptide sequences and uses thereof
CA2493007A1 (en) * 2002-07-19 2004-01-29 Cellzome Ag Protein complexes of the tip60 transcriptional activator protein
US7135556B2 (en) 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
JP2004290170A (en) * 2002-08-02 2004-10-21 Takeda Chem Ind Ltd Use of gene associated with disease
TW200413725A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
US7561919B2 (en) 2002-11-14 2009-07-14 Brainsgate Ltd. SPG stimulation via the greater palatine canal
WO2004046342A2 (en) * 2002-11-20 2004-06-03 Biogen Idec Inc. Novel gene targets and ligands that bind thereto for treatment and diagnosis of carcinomas
AU2003300680A1 (en) * 2002-12-10 2004-07-09 Centre National De La Recherche Scientifique Cnrs Thap proteins as nuclear receptors for chemokines and roles in transcriptional regulation, cell proliferation and cell differentiation
JP4140951B2 (en) * 2002-12-18 2008-08-27 独立行政法人科学技術振興機構 Transcriptional regulator ZHX3
EP2141235B1 (en) 2002-12-29 2014-06-11 Toudai Tlo, Ltd. Adiponectin receptor and gene coding for the same
US7858346B2 (en) 2003-02-03 2010-12-28 Japan Science Technology Agency Regeneration and neogenesis of retinal visual cell-expressing Otx2 protein
US7749695B2 (en) * 2003-03-03 2010-07-06 Alexander Abbas PRO polypeptides for diagnosis of systemic lupus erythematosis
WO2004098515A2 (en) * 2003-04-30 2004-11-18 Agensys, Inc. Nucleic acids and corresponding proteins entitled 109p1d4 useful in treatment and detection of cancer
WO2004104218A1 (en) * 2003-05-23 2004-12-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with x-prolyl aminopeptidase (aminopeptidase p) 1 (xpnpep1)
WO2005023855A2 (en) * 2003-09-10 2005-03-17 Friedrich-Alexander-Uni- Versitatet Erlangen- Nuernberg K203 gene and protein
US7534562B2 (en) * 2003-09-30 2009-05-19 Daiichi Pharmaceutical Co., Ltd. Tetrahydrofolate synthetase gene
WO2005059504A2 (en) * 2003-12-12 2005-06-30 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled receptor gpr34 (gpr34)
JP4590417B2 (en) 2004-01-16 2010-12-01 メルク・シャープ・エンド・ドーム・コーポレイション NPC1L1 (NPC3) and method for identifying this ligand
EP1723227A4 (en) * 2004-02-10 2007-09-19 Dartmouth College NICOTINAMIDE RIBOSIDE KINASE COMPOSITIONS AND METHODS OF USE
US8010189B2 (en) 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
WO2005089505A2 (en) 2004-03-19 2005-09-29 Yale University Detection, isolation and uses of renalase (monoamine oxidase c)
AU2005229434B2 (en) * 2004-03-30 2010-09-30 Nsgene A/S Therapeutic use of a growth factor, NsG33
US20050222040A1 (en) * 2004-04-05 2005-10-06 Blm Group, Inc. Vertebrate peptide modulators of lipid metabolism
WO2006015373A2 (en) 2004-08-04 2006-02-09 Amgen Inc Antibodies to dkk-1
WO2006069592A2 (en) * 2004-12-31 2006-07-06 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg Method for diagnosing an/or predicting preeclampsia and/or related disorders
FI20050011L (en) * 2005-01-05 2006-07-06 Jurilab Ltd Oy Method and test kit for detecting the risk of type 2 diabetes mellitus
WO2006074914A2 (en) * 2005-01-13 2006-07-20 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research Human rna helicase and therapeutic uses thereof
US7521195B1 (en) 2005-07-21 2009-04-21 Celera Corporation Lung disease targets and uses thereof
AU2006315299A1 (en) 2005-11-21 2007-05-24 Yale University Methods of regulating renalase (Monoamine Oxidase C)
US9206242B2 (en) * 2005-11-22 2015-12-08 National University Corporation Nagoya University Application of actin-binding protein to disease associated with cell motility
US7910698B2 (en) 2006-02-24 2011-03-22 Schering Corporation NPC1L1 orthologues
US7960345B2 (en) * 2007-05-02 2011-06-14 Snu R&Db Foundation Angiogenesis inhibitor comprising meteorin as an active ingredient
EP2173379B2 (en) 2007-07-02 2023-07-05 Oncomed Pharmaceuticals, Inc. Compositions and methods for treating and diagnosing cancer
EP2170374A2 (en) * 2007-07-03 2010-04-07 Andreas Reichert Method for treating diseases related to mitochondrial dysfunction
EP2178551A4 (en) * 2007-07-24 2010-07-21 Sanare Invest As NEW PEPTIDES
EP2227487A1 (en) 2007-12-28 2010-09-15 Novo Nordisk A/S Ddr1-mediated cell purification of pancreatic endocrine cells through their progenitors
DK2195013T3 (en) 2008-07-24 2012-02-06 Nsgene As Therapeutic use of a growth factor, METRNL
AU2010226726B8 (en) 2009-03-16 2014-08-14 Pangu Biopharma Limited Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities
AR075989A1 (en) 2009-04-10 2011-05-11 Lilly Co Eli ANTIBODY DKK -1 (DICKKOPF-1) HUMAN DESIGNED BY ENGINEERING
PH12012500982A1 (en) 2009-11-30 2019-07-10 Genentech Inc Antibodies for treating and diagnosing tumors expressing slc34a2 (tat211=seqid2)
CN103096909A (en) 2010-05-04 2013-05-08 Atyr医药公司 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutamyl-prolyl-trna synthetases
WO2012041328A1 (en) 2010-10-01 2012-04-05 Nsgene A/S Use of meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain
JP6185463B2 (en) 2011-07-15 2017-08-23 オンコメッド ファーマシューティカルズ インコーポレイテッド RSPO binder and method of use thereof
JP6145667B2 (en) 2011-09-05 2017-06-14 ホーバ セラピューティクス アンパルトセルスカブ Treatment of allodynia, hyperalgesia, spontaneous pain, and phantom pain
US9181333B2 (en) 2012-07-13 2015-11-10 Oncomed Pharmaceuticals, Inc. RSPO3 binding agents and uses thereof
EP2742935A1 (en) * 2012-12-14 2014-06-18 Tissue Med Biosciences Forschungs- und Entwicklungsgesellschaft mbH SERF2 for the treatment of atrophy and for increasing cell growth
EP2878335B1 (en) 2013-11-10 2018-01-03 Brainsgate Ltd. Implant and delivery system for neural stimulator
CA2961374A1 (en) 2014-09-16 2016-03-24 Oncomed Pharmaceuticals, Inc. Treatment of fibrotic diseases
US10271907B2 (en) 2015-05-13 2019-04-30 Brainsgate Ltd. Implant and delivery system for neural stimulator
EP3548039B1 (en) 2016-12-04 2023-07-19 Alavi Khorassani Moghadam, Marcel Victor Ribavirin for use in the treatment of a mitochondrial disease
US10905766B2 (en) * 2017-03-23 2021-02-02 Oregon State University Therapeutic compositions and methods for treatment of muscle wasting diseases
CA3060514A1 (en) 2017-04-20 2018-10-25 Atyr Pharma, Inc. Compositions and methods for treating lung inflammation
IL281470B2 (en) 2018-09-28 2025-08-01 Harvard College Cell reprogramming to reverse aging and promote organ and tissue regeneration
US12274733B2 (en) 2018-09-28 2025-04-15 President And Fellows Of Harvard College Cellular reprogramming to reverse aging and promote organ and tissue regeneration
CN110910960B (en) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 Acinetobacter baumannii molecular serotype rapid analysis method
AU2021394748A1 (en) * 2020-12-08 2023-06-08 Imagine Pharma Llc Compositions and methods for treating wounds
CA3217602A1 (en) * 2021-05-06 2022-11-10 Kenneth Petersen Prevention and treatment of chemotherapy-induced neuropathic pain
US12252518B2 (en) 2023-01-06 2025-03-18 Life Biosciences, Inc. Methods of treating non-arteritic anterior ischemic optic neuropathy
WO2025068459A2 (en) * 2023-09-29 2025-04-03 Universität Zu Köln Tool and method for disaggregation of polyq strech containing proteins

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049306A1 (en) * 1997-04-29 1998-11-05 Incyte Pharmaceuticals, Inc. Human c-type lectin
GB9711148D0 (en) * 1997-05-31 1997-07-23 Peptide Therapeutics Ltd Human MAFA

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] accession no. NCBI Database accession no. (AI765329) *
See also references of EP1572987A4 *

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7628989B2 (en) 2001-04-10 2009-12-08 Agensys, Inc. Methods of inducing an immune response
US7641905B2 (en) 2001-04-10 2010-01-05 Agensys, Inc. Methods of inducing an immune response
US7259002B2 (en) 2003-01-21 2007-08-21 Bristol-Myers Squibb Company Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
US11401347B2 (en) 2004-04-22 2022-08-02 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
US10597463B2 (en) 2004-04-22 2020-03-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
US9617346B2 (en) 2004-04-22 2017-04-11 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
US8958881B2 (en) 2005-08-19 2015-02-17 Brainsgate Ltd. Neuroprotective electrical stimulation
US9593167B2 (en) 2006-10-27 2017-03-14 Genentech, Inc. Antibodies and immunoconjugates and uses therefor
US10663455B2 (en) 2009-09-16 2020-05-26 Active Motif, Inc. Transcription biomarkers of biological responses and methods of use
US9127268B2 (en) 2009-12-11 2015-09-08 Atyr Pharma, Inc. Aminoacyl tRNA synthetases for modulating inflammation
US9540628B2 (en) 2009-12-11 2017-01-10 Atyr Pharma, Inc. Aminoacyl tRNA synthetases for modulating inflammation
US9328340B2 (en) 2009-12-11 2016-05-03 Atyr Pharma, Inc. Amino acyl tRNA synthetases for modulating inflammation
US9422539B2 (en) 2010-07-12 2016-08-23 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-tRNA synthetases
US9273302B2 (en) 2012-02-16 2016-03-01 Atyr Pharma, Inc. Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
US8835387B2 (en) 2012-02-16 2014-09-16 Atyr Pharma, Inc. Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
US9587235B2 (en) 2013-03-15 2017-03-07 Atyr Pharma, Inc. Histidyl-tRNA synthetase-Fc conjugates
US11180571B2 (en) 2017-04-03 2021-11-23 Hoffmann-La Roche Inc. Antibodies binding to STEAP-1
US11685790B2 (en) 2017-04-03 2023-06-27 Hoffmann-La Roche Inc. Antibodies binding to STEAP-1
US12129306B2 (en) 2017-04-03 2024-10-29 Hoffman-La Roche Inc. Antibodies binding to STEAP-1

Also Published As

Publication number Publication date
EP1572987A4 (en) 2005-11-30
AU2001234944A8 (en) 2006-12-21
AU2001234944A1 (en) 2001-08-14
EP1572987A2 (en) 2005-09-14
WO2001057190A2 (en) 2001-08-09
CA2399776A1 (en) 2001-08-09

Similar Documents

Publication Publication Date Title
WO2001075067A3 (en) Novel nucleic acids and polypeptides
WO2001057188A3 (en) Novel nucleic acids and polypeptides
WO2001057190A3 (en) Novel nucleic acids and polypeptides
WO2002022660A3 (en) Novel nucleic acids and polypeptides
WO2001066689A3 (en) Novel nucleic acids and polypeptides
WO2002031111A3 (en) Novel nucleic acids and polypeptides
WO2001088088A3 (en) Novel nucleic acids and polypeptides
WO2002059260A3 (en) Nucleic acids and polypeptides
WO2003054152A3 (en) Novel nucleic acids and polypeptides
WO2003025148A3 (en) Novel nucleic acids and polypeptides
WO2002070539A3 (en) Novel nucleic acids and polypeptides
WO2003023013A3 (en) Novel nucleic acids and polypeptides
WO2002081731A3 (en) Novel nucleic acids and polypeptides
WO2001053312A8 (en) Novel nucleic acids and polypeptides
WO2001053455A3 (en) Novel nucleic acids and polypeptides
WO2004009834A3 (en) Novel nucleic acids and secreted polypeptides
WO2004080148A3 (en) Novel nucleic acids and polypeptides
WO2003029271A3 (en) Novel nucleic acids and polypeptides
WO2002018424A3 (en) Nucleic acids and polypeptides
WO2001079449A3 (en) Novel nucleic acids and polypeptides
WO2004087874A3 (en) Novel nucleic acids and polypeptides
WO2003080795A3 (en) Novel nucleic acids and secreted polypeptides
WO2001002571A3 (en) An interleukin-1 receptor antagonist and uses thereof
WO2005049806A3 (en) Novel nucleic acids and polypeptides
WO2002044340A3 (en) Novel nucleic acids and polypeptides

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US US US US US US US US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: 2399776

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2001907128

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

WWE Wipo information: entry into national phase

Ref document number: 11218141

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 2001907128

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 11218141

Country of ref document: US