WO2001075076A3 - 33167, a novel human hydrolase and uses therefor - Google Patents

33167, a novel human hydrolase and uses therefor Download PDF

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Publication number
WO2001075076A3
WO2001075076A3 PCT/US2001/010398 US0110398W WO0175076A3 WO 2001075076 A3 WO2001075076 A3 WO 2001075076A3 US 0110398 W US0110398 W US 0110398W WO 0175076 A3 WO0175076 A3 WO 0175076A3
Authority
WO
WIPO (PCT)
Prior art keywords
hydl
nucleic acid
acid molecules
molecules
expression vectors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/010398
Other languages
French (fr)
Other versions
WO2001075076A2 (en
Inventor
Maria Alexandra Glucksmann
Rachel Meyers
Mark Williamson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Priority to AU2001249700A priority Critical patent/AU2001249700A1/en
Priority to EP01922953A priority patent/EP1290190A2/en
Publication of WO2001075076A2 publication Critical patent/WO2001075076A2/en
Publication of WO2001075076A3 publication Critical patent/WO2001075076A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated HYDL-1 nucleic acid molecules, which encode novel hydrolase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing HYDL-1 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an HYDL-1 gene has been introduced or disrupted. The invention still further provides isolated HYDL-1 proteins, fusion proteins, antigenic peptides and anti-HYDL-1 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2001/010398 2000-03-31 2001-03-30 33167, a novel human hydrolase and uses therefor Ceased WO2001075076A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001249700A AU2001249700A1 (en) 2000-03-31 2001-03-30 33167, a novel human hydrolase and uses therefor
EP01922953A EP1290190A2 (en) 2000-03-31 2001-03-30 33167, a novel human hydrolase and uses therefor

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19395400P 2000-03-31 2000-03-31
US60/193,954 2000-03-31
US09/584,568 2000-05-31
US09/584,568 US6500657B1 (en) 2000-03-31 2000-05-31 33167, a novel human hydrolase and uses therefor

Publications (2)

Publication Number Publication Date
WO2001075076A2 WO2001075076A2 (en) 2001-10-11
WO2001075076A3 true WO2001075076A3 (en) 2002-06-20

Family

ID=26889547

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/010398 Ceased WO2001075076A2 (en) 2000-03-31 2001-03-30 33167, a novel human hydrolase and uses therefor

Country Status (4)

Country Link
US (2) US6500657B1 (en)
EP (1) EP1290190A2 (en)
AU (1) AU2001249700A1 (en)
WO (1) WO2001075076A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003294219A1 (en) * 2002-09-05 2004-04-08 Incyte Corporation Enzymes
WO2004042017A2 (en) 2002-10-31 2004-05-21 Genentech, Inc. Methods and compositions for increasing antibody production
CA3007908A1 (en) 2003-03-07 2005-04-14 Dsm Ip Assets B.V. Hydrolases, nucleic acids encoding them and methods for making and using them
US20080070291A1 (en) 2004-06-16 2008-03-20 David Lam Compositions and Methods for Enzymatic Decolorization of Chlorophyll
WO2013068445A1 (en) 2011-11-09 2013-05-16 Sanofi Diacylglycerol lipase and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058675A2 (en) * 1998-05-14 1999-11-18 Chiron Corporation Human genes and gene expression products v
WO2000028045A2 (en) * 1998-11-12 2000-05-18 Incyte Pharmaceuticals, Inc. Human hydrolase proteins
WO2000055173A1 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. Human breast and ovarian cancer associated gene sequences and polypeptides
WO2001002568A2 (en) * 1999-07-02 2001-01-11 Chiron Corporation Human genes and gene expression products

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999052675A1 (en) 1998-04-09 1999-10-21 Schur Henry B Improved particulate matter delivery device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058675A2 (en) * 1998-05-14 1999-11-18 Chiron Corporation Human genes and gene expression products v
WO2000028045A2 (en) * 1998-11-12 2000-05-18 Incyte Pharmaceuticals, Inc. Human hydrolase proteins
WO2000055173A1 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. Human breast and ovarian cancer associated gene sequences and polypeptides
WO2001002568A2 (en) * 1999-07-02 2001-01-11 Chiron Corporation Human genes and gene expression products

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 1 June 1997 (1997-06-01), HILLIER L ET AL: "WashU-merck EST project 1997", XP002194645 *
DATABASE EMBL 11 September 1997 (1997-09-11), "National Cancer Institute, Cancer Genome Anatomy Project", XP002194644 *
DATABASE EMBL 22 July 1999 (1999-07-22), "National Cancer Institute, Cancer Genome Anatomy Project", XP002194646 *

Also Published As

Publication number Publication date
US20020137172A1 (en) 2002-09-26
EP1290190A2 (en) 2003-03-12
US6500657B1 (en) 2002-12-31
AU2001249700A1 (en) 2001-10-15
WO2001075076A2 (en) 2001-10-11

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