WO2001081610A3 - Verfahren zur herstellung von polymilchsäure und vorrichtung hierzu - Google Patents

Verfahren zur herstellung von polymilchsäure und vorrichtung hierzu Download PDF

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Publication number
WO2001081610A3
WO2001081610A3 PCT/EP2001/004482 EP0104482W WO0181610A3 WO 2001081610 A3 WO2001081610 A3 WO 2001081610A3 EP 0104482 W EP0104482 W EP 0104482W WO 0181610 A3 WO0181610 A3 WO 0181610A3
Authority
WO
WIPO (PCT)
Prior art keywords
polylactic acid
dilactide
producing polylactic
lactic acid
corresponding device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/004482
Other languages
English (en)
French (fr)
Other versions
WO2001081610A2 (de
Inventor
Lueder Gerking
Rainer Hagen
Klaus Richter
Frank Idler
Winfried Reimann
Bernd Hanzsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Uhde Inventa Fischer GmbH
Original Assignee
Inventa Fischer GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inventa Fischer GmbH and Co KG filed Critical Inventa Fischer GmbH and Co KG
Priority to EP01940346A priority Critical patent/EP1276890B1/de
Priority to AU2001273954A priority patent/AU2001273954A1/en
Priority to DE50113440T priority patent/DE50113440D1/de
Priority to US10/258,036 priority patent/US6875839B2/en
Priority to KR1020027014145A priority patent/KR100714364B1/ko
Publication of WO2001081610A2 publication Critical patent/WO2001081610A2/de
Publication of WO2001081610A3 publication Critical patent/WO2001081610A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78Preparation processes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08Lactones or lactides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04Filters; Permeable or porous membranes or plates, e.g. dialysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18External loop; Means for reintroduction of fermented biomass or liquid percolate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M39/00Means for cleaning the apparatus or avoiding unwanted deposits of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/09Means for pre-treatment of biological substances by enzymatic treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10Separation or concentration of fermentation products
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56Lactic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Es wird ein Verfahren zur Herstellung von Polymilchsäure vorgeschlagen. Es enthält die Schritte der fermentativen Gewinnung von Milchsäure aus stärkehaltigen landwirtschaftlichen Produkten, der Hochreinigung der Milchsäure durch Ultrafiltration, Nanofiltration und/oder Elektrodialyse, der Aufkonzentrierung der Milchsäure und Herstellung eines Propolymers, der zyklisierenden Depolymerisation zum Dilactid, der Reinigung des Dilactids, der Ringöffnungspolymerisation des Dilactids und der Entmonomerisierung des Polylactids.
PCT/EP2001/004482 2000-04-20 2001-04-19 Verfahren zur herstellung von polymilchsäure und vorrichtung hierzu Ceased WO2001081610A2 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP01940346A EP1276890B1 (de) 2000-04-20 2001-04-19 Verfahren zur herstellung von polymilchsäure und vorrichtung hierzu
AU2001273954A AU2001273954A1 (en) 2000-04-20 2001-04-19 Method for producing polylactic acid and corresponding device
DE50113440T DE50113440D1 (de) 2000-04-20 2001-04-19 Verfahren zur herstellung von polymilchsäure und vorrichtung hierzu
US10/258,036 US6875839B2 (en) 2000-04-20 2001-04-19 Method for producing polylactic acid and corresponding device
KR1020027014145A KR100714364B1 (ko) 2000-04-20 2001-04-19 폴리락트산의 제조방법 및 그 장치

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10020898.3 2000-04-20
DE10020898A DE10020898B4 (de) 2000-04-20 2000-04-20 Verfahren zur Herstellung von Polymilchsäure und Vorrichtung hierzu

Publications (2)

Publication Number Publication Date
WO2001081610A2 WO2001081610A2 (de) 2001-11-01
WO2001081610A3 true WO2001081610A3 (de) 2002-04-11

Family

ID=7640244

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/004482 Ceased WO2001081610A2 (de) 2000-04-20 2001-04-19 Verfahren zur herstellung von polymilchsäure und vorrichtung hierzu

Country Status (10)

Country Link
US (1) US6875839B2 (de)
EP (1) EP1276890B1 (de)
KR (1) KR100714364B1 (de)
CN (1) CN1263865C (de)
AT (1) ATE382703T1 (de)
AU (1) AU2001273954A1 (de)
DE (2) DE10020898B4 (de)
ES (1) ES2300338T3 (de)
PT (1) PT1276890E (de)
WO (1) WO2001081610A2 (de)

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FR2810792B1 (fr) * 2000-06-22 2003-07-04 Commissariat Energie Atomique Transistor mos vertical a grille enterree et procede de fabrication de celui-ci
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KR100507698B1 (ko) * 2002-05-31 2005-08-11 주식회사 효성 뱃치식 폴리에스터 중합장치
CA2570171A1 (en) * 2004-06-09 2005-12-29 Alexander Sunguroff Methods of making nanotechnological and macromolecular biomimetic structures
JP3734821B1 (ja) 2004-09-30 2006-01-11 株式会社グリーン環境テクノロジー ポリ乳酸の製造方法、及びポリ乳酸製造装置
DE102005028016A1 (de) * 2005-06-16 2006-12-21 Uhde Gmbh Beschichtetes Düngemittel mit kontrollierter Wirkstofffreisetzung und Verfahren zu dessen Herstellung
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US20080146822A1 (en) * 2006-11-28 2008-06-19 Purac Biochem B.V. Stable lactide particles
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TWM321371U (en) * 2006-12-22 2007-11-01 Chun-Chih Lai Flaky texture for polylactic acid and thin wood sheet
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EP2031083A1 (de) * 2007-09-03 2009-03-04 Uhde Inventa-Fischer GmbH Verfahren zur Herstellung von Milchsäuredilactid oder daraus herstellbaren Polyestern
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DE102007045701B3 (de) * 2007-09-24 2009-05-14 Uhde Gmbh Gewinnung von Milchsäure durch Fermentation und Extraktion mit Aminen
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CN102066305B (zh) * 2008-06-20 2015-11-25 旭化成化学株式会社 α-羟酸的制造方法
CN101665567B (zh) 2008-09-01 2011-11-23 南京工业大学 卡宾衍生物催化的环状化合物可调控开环聚合方法
CN101665565B (zh) * 2008-09-01 2012-01-04 南京工业大学 一种用卡宾衍生物催化制备聚乳酸的方法
CN101665566B (zh) 2008-09-01 2012-01-04 南京工业大学 一种利用双螺杆挤出机制备聚乳酸及其制品的方法
WO2010089765A1 (en) * 2009-01-07 2010-08-12 Praj Industries Limited Enzymatic polymerization process for the production of polylactide polymers
BE1018628A3 (fr) * 2009-01-16 2011-05-03 Futerro Sa Acide polylactique isotactique et son procede de fabrication.
KR101154029B1 (ko) 2009-05-20 2012-06-07 한국화학연구원 젖산에스테르로부터 락타이드의 직접 전환용 촉매 및 이를 이용한 락타이드의 제조방법
DE102009036080A1 (de) * 2009-08-04 2011-02-17 Siemens Aktiengesellschaft Verfahren zum Abbau von organischen Schadstoffen in industriellem Abwasser und zugehörige Anlage
CN101665564B (zh) * 2009-09-24 2011-09-14 同济大学 膜式脱水型乳酸缩聚反应装置
DE102010002065B4 (de) * 2010-02-17 2014-04-10 Deutsches Institut Für Lebensmitteltechnik E.V. Vorrichtung und integriertes Herstellungsverfahren für Ammoniumlactat
EA201300208A1 (ru) * 2010-08-02 2013-08-30 Спрингхилл С.А. Процесс получения биоразлагаемого полимера, исходя из молочной кислоты, синтезированной микробиологическим способом, и аппаратура для его получения
CN102712745A (zh) * 2010-11-26 2012-10-03 洋泰能源科技有限公司 聚乳酸和高导电性聚乳酸聚合物的制造方法及其制造设备
CN102020628B (zh) * 2011-01-06 2013-07-31 云南富集生物材料科技有限公司 一种聚乳酸中间体丙交酯制备工艺的改进方法
US9416222B2 (en) * 2011-11-04 2016-08-16 Thyssenkrupp Industrial Solutions Ag Quality test for polymerizable lactic acid and method for producing same
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EP2746313B1 (de) 2012-12-18 2017-08-30 Uhde Inventa-Fischer GmbH Vorrichtung und Verfahren zur Abtrennung eines cyclischen Diesters aus Polymerschmelzen
CN105142768B (zh) * 2013-04-26 2019-07-30 希乐克公司 将羟基羧酸加工成聚合物
CN103451244B (zh) * 2013-08-29 2015-08-26 山东省食品发酵工业研究设计院 一种屎肠球菌在制备l-乳酸中的应用
CN105733000A (zh) * 2014-12-10 2016-07-06 黑龙江鑫达企业集团有限公司 一种聚乳酸薄膜的制备
CN106117526A (zh) * 2016-07-13 2016-11-16 张静 一种亲水性聚乳酸复合材料的制备方法
CN106633726A (zh) * 2016-12-16 2017-05-10 全椒祥瑞塑胶有限公司 一种可降解塑料
US20190352676A1 (en) * 2018-05-21 2019-11-21 Jupeng Bio, Inc. Process for Obtaining Protein-Rich Nutrient Supplements from Bacterial Fermentation Process
CO2018007766A1 (es) * 2018-07-26 2018-10-31 Cuervo Garces Laura Viviana Método de obtención de ácido poliláctico (pla) a partir del suero de queso
CN109456581A (zh) * 2018-09-30 2019-03-12 嘉兴凡高电子商务有限公司 一种儿童玩具用降解的pla生物复合材料及其制备方法
CN110981557A (zh) * 2019-12-10 2020-04-10 安徽尘缘节能环保科技有限公司 一种废弃蛋白微波酸解制备复合氨基酸系统
CN114377421B (zh) * 2022-02-18 2024-07-02 华陆工程科技有限责任公司 一种乳酸低聚反应与脱水装置

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Also Published As

Publication number Publication date
WO2001081610A2 (de) 2001-11-01
DE10020898A1 (de) 2002-01-10
CN1263865C (zh) 2006-07-12
KR100714364B1 (ko) 2007-05-02
CN1430676A (zh) 2003-07-16
DE10020898B4 (de) 2004-02-05
KR20030016249A (ko) 2003-02-26
EP1276890A2 (de) 2003-01-22
EP1276890B1 (de) 2008-01-02
DE50113440D1 (de) 2008-02-14
AU2001273954A1 (en) 2001-11-07
ATE382703T1 (de) 2008-01-15
US6875839B2 (en) 2005-04-05
PT1276890E (pt) 2008-01-17
ES2300338T3 (es) 2008-06-16
US20030158360A1 (en) 2003-08-21

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