WO2001085143A3 - Compositions pharmaceutiques pour administration transdermique d' agents anti-inflammatoires - Google Patents

Compositions pharmaceutiques pour administration transdermique d' agents anti-inflammatoires Download PDF

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Publication number
WO2001085143A3
WO2001085143A3 PCT/FR2001/001442 FR0101442W WO0185143A3 WO 2001085143 A3 WO2001085143 A3 WO 2001085143A3 FR 0101442 W FR0101442 W FR 0101442W WO 0185143 A3 WO0185143 A3 WO 0185143A3
Authority
WO
WIPO (PCT)
Prior art keywords
active principle
inflammatory agents
transdermal administration
pharmaceutical compositions
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2001/001442
Other languages
English (en)
Other versions
WO2001085143A2 (fr
Inventor
Brigitte Illel
Jean-Pierre Vergnaud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Priority to JP2001581797A priority Critical patent/JP5149477B2/ja
Priority to EP01934105.6A priority patent/EP1283704B1/fr
Priority to AU2001260414A priority patent/AU2001260414A1/en
Publication of WO2001085143A2 publication Critical patent/WO2001085143A2/fr
Publication of WO2001085143A3 publication Critical patent/WO2001085143A3/fr
Anticipated expiration legal-status Critical
Priority to US11/549,168 priority patent/US20070071688A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention se rapporte à une composition pharmaceutique pour administration transdermique comprenant: une matrice polymérique de relargage capable de former un film souple après séchage, choi sie parmi des polymères ou copolymères cellulosiques, cette matrice étant présente à une concentration ne dépassant pas 6 % du poids de la composition; un principe actif choisi parmi le groupe des agents anti-inflammatoires non stéroïdiens comportant au moins un groupement carboxylique ou carboxitate métallique; un promoteur d'absorption transcutanée du principe actif; de l'eau; au moins un solvant non aqueux physiologiquement acceptable capable de dissoudre la matrice de relargage, le principe actif et le promoteur d'absorption transcutanée ainsi que de s'éliminer rapidement par évaporation au contact de la peau.
PCT/FR2001/001442 2000-05-12 2001-05-11 Compositions pharmaceutiques pour administration transdermique d' agents anti-inflammatoires Ceased WO2001085143A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2001581797A JP5149477B2 (ja) 2000-05-12 2001-05-11 抗炎症剤の経皮投与用医薬組成物
EP01934105.6A EP1283704B1 (fr) 2000-05-12 2001-05-11 Compositions pharmaceutiques pour administration transdermique d' agents anti-inflammatoires
AU2001260414A AU2001260414A1 (en) 2000-05-12 2001-05-11 Pharmaceutical compositions for transdermal administration of anti-inflammatory agents
US11/549,168 US20070071688A1 (en) 2000-05-12 2006-10-13 Pharmaceutical compositions for transdermal administration of anti-inflammatory agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR00/06048 2000-05-12
FR0006048A FR2808685B1 (fr) 2000-05-12 2000-05-12 Compositions pharmaceutiques pour administration transdermique d'agents anti-inflammatoires

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/549,168 Continuation US20070071688A1 (en) 2000-05-12 2006-10-13 Pharmaceutical compositions for transdermal administration of anti-inflammatory agents

Publications (2)

Publication Number Publication Date
WO2001085143A2 WO2001085143A2 (fr) 2001-11-15
WO2001085143A3 true WO2001085143A3 (fr) 2002-05-10

Family

ID=8850140

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2001/001442 Ceased WO2001085143A2 (fr) 2000-05-12 2001-05-11 Compositions pharmaceutiques pour administration transdermique d' agents anti-inflammatoires

Country Status (6)

Country Link
US (2) US20030152611A1 (fr)
EP (1) EP1283704B1 (fr)
JP (1) JP5149477B2 (fr)
AU (1) AU2001260414A1 (fr)
FR (1) FR2808685B1 (fr)
WO (1) WO2001085143A2 (fr)

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IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
ES2532906T5 (es) 2002-10-25 2022-03-23 Foamix Pharmaceuticals Ltd Espuma cosmética y farmacéutica
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7575739B2 (en) * 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US20080069779A1 (en) * 2003-08-04 2008-03-20 Foamix Ltd. Foamable vehicle and vitamin and flavonoid pharmaceutical compositions thereof
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
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US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US7772213B2 (en) * 2006-07-27 2010-08-10 Nathan Strick Composition for the treatment of inflammatory conditions
JP4836146B2 (ja) * 2006-10-24 2011-12-14 有限会社日本健康科学研究センター 皮膚上にフィルムを形成するフィルム製剤
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
PL1986473T3 (pl) * 2007-04-03 2017-07-31 Tsinghua University Organiczne urządzenie elektroluminescencyjne
KR20150058566A (ko) 2007-06-04 2015-05-28 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 ｎｓａｉａ 약물전구체 및 이들의 새로운 의약적 용도
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
US8518376B2 (en) 2007-12-07 2013-08-27 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009072007A2 (fr) 2007-12-07 2009-06-11 Foamix Ltd. Porteurs, formulations, procédés pour formuler des agents actifs instables pour application externe et utilisations associées
EP2242476A2 (fr) 2008-01-14 2010-10-27 Foamix Ltd. Compositions pharmaceutiques pouvant mousser de poloxamère avec des agents actifs et/ou des cellules thérapeutiques, et utilisations
BR122021011394B1 (pt) 2008-12-04 2021-09-28 Chongxi Yu Composição de alta penetração de um fármaco principal, e uso de uma hpc
WO2010125470A2 (fr) 2009-04-28 2010-11-04 Foamix Ltd. Véhicule moussant et compositions pharmaceutiques comportant des solvants polaires aprotiques et leurs utilisations
CA2769677A1 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes a base d'agents non tensioactifs non polymeres, mousses legeres, et leurs utilisations
WO2011013009A2 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes non tensioactives, mousses légères, et leurs utilisations
WO2011064631A1 (fr) 2009-10-02 2011-06-03 Foamix Ltd. Compositions moussantes dépourvues d'agent tensioactif et d'eau et mousses cassables et leurs utilisations
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
WO2011061155A1 (fr) 2009-11-17 2011-05-26 Bayer Consumer Care Ag Formulations antifongiques et leur utilisation
US8174881B2 (en) 2009-11-24 2012-05-08 Micron Technology, Inc. Techniques for reducing disturbance in a semiconductor device
MX365427B (es) 2011-05-03 2019-06-03 Aponia Laboratories Inc Composiciones transdermicas de ibuprofeno y metodos de uso de las mismas.
EP2714019A1 (fr) * 2011-05-26 2014-04-09 Novartis AG Compositions destinées à l'administration percutanée d'agents physiologiquement actifs
GB201120908D0 (en) * 2011-12-06 2012-01-18 Reckitt Benckiser Healthcare Patch containing non-steroidal anti-inflammatory drug
US10398641B2 (en) 2016-09-08 2019-09-03 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
EP3720417B1 (fr) 2017-12-04 2023-11-01 Johnson & Johnson Consumer Inc. Composition d'émulsion topique contenant un médicament anti-inflammatoire non stéroïdien
WO2026068000A1 (fr) * 2024-09-30 2026-04-02 Symrise Ag Esters d'alkyle ramifiés d'acides carboxyliques oméga-insaturés en tant que substituts de silicone

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59216822A (ja) * 1983-05-26 1984-12-06 Terumo Corp 被膜形成外用製剤
EP0450123A1 (fr) * 1990-04-05 1991-10-09 Knoll AG Composition pharmaceutique pour application topique contenant du diclofenac-sodium
JPH04234314A (ja) * 1990-12-28 1992-08-24 Mikasa Seiyaku Kk 全身性経皮投与製剤
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WO1996030000A1 (fr) * 1995-03-30 1996-10-03 Sanofi Composition pharmaceutique filmogene pour administration transdermique
WO1999039713A1 (fr) * 1998-02-09 1999-08-12 Chong Kun Dang Pharmaceutical Corp. Composition de gel aqueux a base d'alcool contenant du piroxicam

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JPS59216822A (ja) * 1983-05-26 1984-12-06 Terumo Corp 被膜形成外用製剤
EP0450123A1 (fr) * 1990-04-05 1991-10-09 Knoll AG Composition pharmaceutique pour application topique contenant du diclofenac-sodium
US5350769A (en) * 1990-10-30 1994-09-27 Ss Pharmaceutical Co., Ltd. Antiinflammatory gel preparation
JPH04234314A (ja) * 1990-12-28 1992-08-24 Mikasa Seiyaku Kk 全身性経皮投与製剤
WO1996030000A1 (fr) * 1995-03-30 1996-10-03 Sanofi Composition pharmaceutique filmogene pour administration transdermique
WO1999039713A1 (fr) * 1998-02-09 1999-08-12 Chong Kun Dang Pharmaceutical Corp. Composition de gel aqueux a base d'alcool contenant du piroxicam

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Title
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Also Published As

Publication number Publication date
US20070071688A1 (en) 2007-03-29
FR2808685A1 (fr) 2001-11-16
WO2001085143A2 (fr) 2001-11-15
AU2001260414A1 (en) 2001-11-20
EP1283704A2 (fr) 2003-02-19
JP5149477B2 (ja) 2013-02-20
US20030152611A1 (en) 2003-08-14
JP2003532668A (ja) 2003-11-05
FR2808685B1 (fr) 2004-10-08
EP1283704B1 (fr) 2013-12-18

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