WO2001087487A3 - Bidirectional flow centrifugal microfluidic devices - Google Patents

Bidirectional flow centrifugal microfluidic devices Download PDF

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Publication number
WO2001087487A3
WO2001087487A3 PCT/US2001/015824 US0115824W WO0187487A3 WO 2001087487 A3 WO2001087487 A3 WO 2001087487A3 US 0115824 W US0115824 W US 0115824W WO 0187487 A3 WO0187487 A3 WO 0187487A3
Authority
WO
WIPO (PCT)
Prior art keywords
microfluidic devices
bidirectional flow
flow centrifugal
centrifugal microfluidic
motivated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/015824
Other languages
French (fr)
Other versions
WO2001087487A2 (en
Inventor
Gregory J Kellogg
Bruce Carvalho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tecan Trading AG
Original Assignee
Tecan Trading AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecan Trading AG filed Critical Tecan Trading AG
Priority to EP01933351A priority Critical patent/EP1284818B1/en
Priority to JP2001583937A priority patent/JP2003533682A/en
Priority to DE60124699T priority patent/DE60124699T2/en
Priority to AU2001259786A priority patent/AU2001259786A1/en
Publication of WO2001087487A2 publication Critical patent/WO2001087487A2/en
Publication of WO2001087487A3 publication Critical patent/WO2001087487A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
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    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4331—Mixers with bended, curved, coiled, wounded mixing tubes or comprising elements for bending the flow
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    • B01F35/71725—Feed mechanisms characterised by the means for feeding the components to the mixer using centrifugal forces
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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)

Abstract

This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention particularly provides microsystem platforms for achieving efficient mixing of one or a plurality of fluids on the surface of the platform when fluid flow is motivated by centripetal force produce by rotation.
PCT/US2001/015824 2000-05-15 2001-05-15 Bidirectional flow centrifugal microfluidic devices Ceased WO2001087487A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP01933351A EP1284818B1 (en) 2000-05-15 2001-05-15 Bidirectional flow centrifugal microfluidic devices
JP2001583937A JP2003533682A (en) 2000-05-15 2001-05-15 Bidirectional flow centrifugal microfluidic device
DE60124699T DE60124699T2 (en) 2000-05-15 2001-05-15 TWO DIRECTION FLOW ZENTRIFUGALMIKROFLUID DEVICES
AU2001259786A AU2001259786A1 (en) 2000-05-15 2001-05-15 Bidirectional flow centrifugal microfluidic devices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20426400P 2000-05-15 2000-05-15
US60/204,264 2000-05-15

Publications (2)

Publication Number Publication Date
WO2001087487A2 WO2001087487A2 (en) 2001-11-22
WO2001087487A3 true WO2001087487A3 (en) 2002-04-18

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2001/015824 Ceased WO2001087487A2 (en) 2000-05-15 2001-05-15 Bidirectional flow centrifugal microfluidic devices
PCT/US2001/015823 Ceased WO2001087486A2 (en) 2000-05-15 2001-05-15 Microfluidics devices and methods for performing cell based assays

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2001/015823 Ceased WO2001087486A2 (en) 2000-05-15 2001-05-15 Microfluidics devices and methods for performing cell based assays

Country Status (7)

Country Link
US (3) US6527432B2 (en)
EP (2) EP1284817A2 (en)
JP (2) JP2003533681A (en)
AT (1) ATE345868T1 (en)
AU (2) AU2001259785A1 (en)
DE (1) DE60124699T2 (en)
WO (2) WO2001087487A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
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US7400983B2 (en) 2002-12-20 2008-07-15 Dako Denmark A/S Information notification sample processing system and methods of biological slide processing
US12589393B2 (en) 2021-02-05 2026-03-31 Boe Technology Group Co., Ltd. Microfluidic chip

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US20050069923A1 (en) * 1996-07-08 2005-03-31 Mullis Kary Banks Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
US6248542B1 (en) * 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
ATE272213T1 (en) * 1999-06-18 2004-08-15 Gamera Bioscience Corp DEVICES AND METHODS FOR PERFORMING MINIATURIZED HOMOGENEOUS TESTS
NZ533466A (en) * 1999-06-28 2005-10-28 California Inst Of Techn Microfabricated elastomeric valve and pump systems
US20020151078A1 (en) * 2000-05-15 2002-10-17 Kellogg Gregory J. Microfluidics devices and methods for high throughput screening
US6734401B2 (en) * 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US6720187B2 (en) * 2000-06-28 2004-04-13 3M Innovative Properties Company Multi-format sample processing devices
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