WO2001088520A3 - Ion-selective solid-state polymeric membrane electrodes - Google Patents

Ion-selective solid-state polymeric membrane electrodes Download PDF

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Publication number
WO2001088520A3
WO2001088520A3 PCT/US2001/016165 US0116165W WO0188520A3 WO 2001088520 A3 WO2001088520 A3 WO 2001088520A3 US 0116165 W US0116165 W US 0116165W WO 0188520 A3 WO0188520 A3 WO 0188520A3
Authority
WO
WIPO (PCT)
Prior art keywords
ion
electrically conducting
conducting member
polymeric membrane
insulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/016165
Other languages
French (fr)
Other versions
WO2001088520A2 (en
Inventor
Narayanan Ramamurthy
Mark E Meyerhoff
Robert P Baugh
Colin P Larkin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Inc
University of Michigan System
University of Michigan Ann Arbor
Original Assignee
Medtronic Inc
University of Michigan System
University of Michigan Ann Arbor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc, University of Michigan System, University of Michigan Ann Arbor filed Critical Medtronic Inc
Priority to EP01939132A priority Critical patent/EP1287345A2/en
Priority to AU2001264683A priority patent/AU2001264683A1/en
Priority to JP2001584865A priority patent/JP2003533694A/en
Publication of WO2001088520A2 publication Critical patent/WO2001088520A2/en
Publication of WO2001088520A3 publication Critical patent/WO2001088520A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/333—Ion-selective electrodes or membranes
    • G01N27/3335—Ion-selective electrodes or membranes the membrane containing at least one organic component

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

An improved ion-sensing electrode for detecting ions or polyions is provided having an electrically conducting member sheathed or coated with a layer of insulation except at an exposed, uninsulated area, where the insulation free surface of the electrically conducting member is texturized, and a polymeric membrane coated on the insulation-free surface of the electrically conducting member, where the ion selective membrane includes an ionophore. The texturized surface improves the starting EMF stability and reproducibility of the ion-sensing electrodes, and further improves membrane adherence to the electrically conducting member.
PCT/US2001/016165 2000-05-18 2001-05-16 Ion-selective solid-state polymeric membrane electrodes Ceased WO2001088520A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01939132A EP1287345A2 (en) 2000-05-18 2001-05-16 Ion-selective solid-state polymeric membrane electrodes
AU2001264683A AU2001264683A1 (en) 2000-05-18 2001-05-16 Ion-selective solid-state polymeric membrane electrodes
JP2001584865A JP2003533694A (en) 2000-05-18 2001-05-16 Ion-selective solid-state polymer membrane electrode

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57337800A 2000-05-18 2000-05-18
US09/573,378 2000-05-18

Publications (2)

Publication Number Publication Date
WO2001088520A2 WO2001088520A2 (en) 2001-11-22
WO2001088520A3 true WO2001088520A3 (en) 2002-10-17

Family

ID=24291747

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016165 Ceased WO2001088520A2 (en) 2000-05-18 2001-05-16 Ion-selective solid-state polymeric membrane electrodes

Country Status (5)

Country Link
US (1) US20050006237A1 (en)
EP (1) EP1287345A2 (en)
JP (1) JP2003533694A (en)
AU (1) AU2001264683A1 (en)
WO (1) WO2001088520A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100926476B1 (en) * 2003-07-09 2009-11-13 어번 유니버시티 Reversible electrochemical sensors for polyions

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8097135B2 (en) 2003-07-09 2012-01-17 Auburn University Reversible electrochemical sensors for polyions
US7439069B2 (en) * 2004-02-27 2008-10-21 Nippoldt Douglas D Blood coagulation test cartridge, system, and method
US7422905B2 (en) 2004-02-27 2008-09-09 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US7658826B2 (en) * 2004-03-01 2010-02-09 Hach Company Reference electrode
US7399637B2 (en) * 2004-04-19 2008-07-15 Medtronic, Inc. Blood coagulation test cartridge, system, and method
WO2005116623A2 (en) * 2004-05-17 2005-12-08 Medtronic, Inc. Point of care heparin determination system
US7595149B1 (en) 2004-11-08 2009-09-29 University Of Kentucky Research Foundation Methods for cancer detection
JP2009503545A (en) * 2005-08-05 2009-01-29 オーバーン・ユニバーシティ Sensor, polyion concentration detection method, reversible electrochemical cell device, and cell recovery method
US8398835B2 (en) * 2006-03-23 2013-03-19 Hach Company Unitary ionic probe
GB2441784A (en) * 2006-09-13 2008-03-19 Rtc North Ltd Device for obtaining and analysing a biological fluid
EP1936365B1 (en) * 2006-12-22 2014-03-05 Metroglas AG Method of determining a reference electrode on an ion-selective electrode having a solid contact
ES2310476B1 (en) * 2007-05-29 2009-11-17 Universitat Rovira I Virgili SELECTED ELECTRODES OF SOLID CONTACT IONS BASED ON CARBON NANOTUBES.
US7740748B2 (en) * 2008-10-27 2010-06-22 General Electric Company Electrophoresis system and method
WO2010113939A1 (en) 2009-03-30 2010-10-07 味の素株式会社 Diphenylmethane compound
CN102262116B (en) * 2010-05-28 2014-03-26 中国科学院烟台海岸带研究所 Method and device for detecting polymer film ion selective electrode
CN102445483B (en) * 2011-09-30 2014-01-15 中国科学院烟台海岸带研究所 Method for detecting heparins
EP2811983B1 (en) 2012-09-17 2019-05-01 W.R. Grace & CO. - CONN. Functionalized particulate support material and methods of making and using the same
EP2812091B1 (en) 2012-09-17 2021-03-10 W.R. Grace & CO. - CONN. Chromatography media and devices
US9562885B2 (en) * 2013-05-17 2017-02-07 Umm Al-Qura University Ionophore and polymer membrane selective for aluminum (III) ion
JP6554272B2 (en) * 2013-08-27 2019-07-31 オルガノ株式会社 Hydrogen ion selective electrode, pH measuring method and sensitive membrane
US9281219B2 (en) 2013-09-18 2016-03-08 Suprasensor Technologies, Llc Molecular receptor-based chemical field-effect transistor (CHEMFET) devices, systems, and methods for in-situ nitrate monitoring in field soils
KR20160067152A (en) * 2013-10-02 2016-06-13 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 Organ mounted electronics
ES2887110T3 (en) 2014-01-16 2021-12-21 Grace W R & Co Affinity Chromatography Media and Chromatography Devices
PL3137209T3 (en) 2014-05-02 2023-01-02 W.R. Grace & Co. - Conn. Functionalized support material and methods of making and using functionalized support material
US10259919B2 (en) 2014-09-09 2019-04-16 University Of Delaware Perchlorate ion permselective membranes
KR102566292B1 (en) 2015-06-05 2023-08-10 더블유.알. 그레이스 앤드 캄파니-콘. Adsorbent bioprocessing clarifiers and methods of making and using the same
DE102018118792A1 (en) * 2017-08-14 2019-02-14 Endress+Hauser Conducta Gmbh+Co. Kg Method for manufacturing an ISE half cell, ISE half cell, sensor and multiparameter sensor
CN109813789B (en) * 2017-11-20 2024-05-07 上海柏中观澈智能科技有限公司 Specific ion detection sensor and preparation method thereof
US11883813B2 (en) 2018-08-30 2024-01-30 Technion Research & Development Foundation Limited Carbazolium salt and use thereof in anion exchange membranes
CN111855754B (en) * 2019-04-29 2021-12-03 深圳安吉尔饮水产业集团有限公司 Water hardness detection probe, sensor, detection method and water softener
CN110763744A (en) * 2019-11-12 2020-02-07 长沙理工大学 Preparation of copper ion electrochemical sensor
FR3103279B1 (en) * 2019-11-18 2021-10-08 Commissariat Energie Atomique METHOD OF MANUFACTURING A POLYMERIC MEMBRANE FOR THE POTENTIOMETRIC DETECTION OF AN ANALYTE PRESENT IN A FLUID
CN115184435B (en) * 2022-07-25 2024-07-23 中国科学院兰州化学物理研究所 Detection method of ions in different media water using all-solid-state polymer membrane ion selective electrode based on MXene conductive layer
CN115825200B (en) * 2022-11-07 2024-09-20 叶绿体(北京)生物医药有限公司 Miniature solid-state calcium ion selective electrode and preparation method thereof

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5957156A (en) * 1982-09-28 1984-04-02 Toshiba Corp Ion selective electrode
DE3438221A1 (en) * 1984-10-18 1986-04-24 Ließ, Hans-Dieter, Prof. Dr.-Ing., 8014 Neubiberg Carbon electrodes, especially microelectrodes made of carbon fibres
EP0333862A1 (en) * 1986-12-10 1989-09-27 Terumo Kabushiki Kaisha Ion carrier membrane and ion sensor provided with same
EP0339613A2 (en) * 1988-04-28 1989-11-02 Hitachi, Ltd. Ion selective electrode
US5401377A (en) * 1993-08-06 1995-03-28 Biomedix, Inc. Ion-selective sensor with polymeric membrane having phospholipid dispersed therein
DE4427921A1 (en) * 1994-08-06 1996-02-15 Forschungszentrum Juelich Gmbh Chemical sensors, especially biosensors, based on silicon
US5607567A (en) * 1992-03-10 1997-03-04 The Board Of Regents Acting For And On Behalf Of University Of Michigan Protamine-responsive polymeric membrane electrode
EP0767372A1 (en) * 1995-10-06 1997-04-09 Metrohm Ag Ion-selective electrode

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115209A (en) * 1974-10-30 1978-09-19 Research Corporation Method of determining ion activity using coated ion selective electrodes
US3923627A (en) * 1974-11-01 1975-12-02 Gen Electric Miniature probe containing multifunctional electrochemical sensing electrodes
US5314601A (en) * 1989-06-30 1994-05-24 Eltech Systems Corporation Electrodes of improved service life
CA2047991A1 (en) * 1991-02-04 1992-08-05 John Musacchio Solid contact system for potentiometric sensors
US5064556A (en) * 1991-02-13 1991-11-12 Provision, Inc. Golf club cleaning composition and method
US5236570A (en) * 1992-03-10 1993-08-17 University Of Michigan Heparin-selective polymeric membrane electrode
US5453171A (en) * 1992-03-10 1995-09-26 The Board Of Regents Of The University Of Michigan Heparin-selective polymeric membrane electrode
US5911862A (en) * 1993-09-15 1999-06-15 Chiron Diagnostics Corporation Material for establishing solid state contact for ion selective electrodes
DE4437274C2 (en) * 1994-10-18 1998-11-05 Inst Chemo Biosensorik Analyte selective sensor

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5957156A (en) * 1982-09-28 1984-04-02 Toshiba Corp Ion selective electrode
DE3438221A1 (en) * 1984-10-18 1986-04-24 Ließ, Hans-Dieter, Prof. Dr.-Ing., 8014 Neubiberg Carbon electrodes, especially microelectrodes made of carbon fibres
EP0333862A1 (en) * 1986-12-10 1989-09-27 Terumo Kabushiki Kaisha Ion carrier membrane and ion sensor provided with same
EP0339613A2 (en) * 1988-04-28 1989-11-02 Hitachi, Ltd. Ion selective electrode
US5607567A (en) * 1992-03-10 1997-03-04 The Board Of Regents Acting For And On Behalf Of University Of Michigan Protamine-responsive polymeric membrane electrode
US5401377A (en) * 1993-08-06 1995-03-28 Biomedix, Inc. Ion-selective sensor with polymeric membrane having phospholipid dispersed therein
DE4427921A1 (en) * 1994-08-06 1996-02-15 Forschungszentrum Juelich Gmbh Chemical sensors, especially biosensors, based on silicon
EP0767372A1 (en) * 1995-10-06 1997-04-09 Metrohm Ag Ion-selective electrode

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1287345A2 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100926476B1 (en) * 2003-07-09 2009-11-13 어번 유니버시티 Reversible electrochemical sensors for polyions

Also Published As

Publication number Publication date
US20050006237A1 (en) 2005-01-13
AU2001264683A1 (en) 2001-11-26
WO2001088520A2 (en) 2001-11-22
EP1287345A2 (en) 2003-03-05
JP2003533694A (en) 2003-11-11

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