WO2001091756A3 - S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders - Google Patents
S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders Download PDFInfo
- Publication number
- WO2001091756A3 WO2001091756A3 PCT/IB2001/000933 IB0100933W WO0191756A3 WO 2001091756 A3 WO2001091756 A3 WO 2001091756A3 IB 0100933 W IB0100933 W IB 0100933W WO 0191756 A3 WO0191756 A3 WO 0191756A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- disorder
- disorders
- anxiety
- treatment
- psychotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Priority Applications (20)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK04013380T DK1468686T3 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for the treatment of psychiatric disorders |
| PL01365576A PL365576A1 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders |
| UA2002119557A UA79425C2 (en) | 2000-06-02 | 2001-05-28 | S-methyl dihydroziprasidone for treatment of psychiatric disorders |
| AU2001258690A AU2001258690A1 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders |
| CA002410618A CA2410618A1 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for treatment of psychiatric disorders |
| DE60124093T DE60124093D1 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for the treatment of eye diseases. |
| MXPA02011862A MXPA02011862A (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders. |
| EA200201168A EA007068B1 (en) | 2000-06-02 | 2001-05-28 | 3-methyl-dihydro-ziprasidone for treatment of psychiatric disorders |
| HU0301747A HUP0301747A2 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders |
| JP2001587771A JP2003534381A (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for the treatment of psychiatric and eye disorders |
| EP01932011A EP1286672B1 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for the treatment of ocular disorders. |
| SK1662-2002A SK16622002A3 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders |
| BR0111271-6A BR0111271A (en) | 2000-06-02 | 2001-05-28 | S-methyl dihydro-ziprasidone for treatment of psychiatric and eye disorders |
| IL15278201A IL152782A0 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders |
| EEP200200670A EE200200670A (en) | 2000-06-02 | 2001-05-28 | S-methyldihydroziprasidone for the treatment of psychiatric and ocular disorders |
| HR20020953A HRP20020953A2 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders |
| IL152782A IL152782A (en) | 2000-06-02 | 2002-11-11 | S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders |
| BG107267A BG107267A (en) | 2000-06-02 | 2002-11-12 | S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders |
| IS6619A IS6619A (en) | 2000-06-02 | 2002-11-14 | S-methyl-dihydro-siprazidone for the treatment of psychiatric and eye disorders |
| NO20025760A NO325077B1 (en) | 2000-06-02 | 2002-11-29 | Use of S-methyl-dihydro-ziprasidone for the preparation of a pharmaceutical composition and a pharmaceutical composition. |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20913600P | 2000-06-02 | 2000-06-02 | |
| US60/209,136 | 2000-06-02 | ||
| US21217200P | 2000-06-16 | 2000-06-16 | |
| US60/212,172 | 2000-06-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001091756A2 WO2001091756A2 (en) | 2001-12-06 |
| WO2001091756A3 true WO2001091756A3 (en) | 2002-09-26 |
Family
ID=26903852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IB2001/000933 Ceased WO2001091756A2 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders |
Country Status (44)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7667037B2 (en) | 2003-10-24 | 2010-02-23 | Teva Pharmaceutical Industries Ltd. | Processes for preparation of ziprasidone |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003296991A1 (en) | 2002-12-13 | 2004-07-09 | Regents Of The University Of Minnesota | Scleral depressor |
| ES2250001B1 (en) * | 2004-09-29 | 2007-06-01 | Medichem, S.A. | PROCESS FOR THE PURIFICATION OF ZIPRASIDONA. |
| JP2012174228A (en) * | 2011-02-24 | 2012-09-10 | Kyocera Corp | Program protection device and communication apparatus |
| WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| US9981041B2 (en) * | 2016-08-23 | 2018-05-29 | Ira Jason Salzman | Ophthalmic lubricating spray |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000059489A2 (en) * | 1999-04-06 | 2000-10-12 | Sepracor Inc. | Methods and compositions for the treatment of psychotic and related disorders using ziprasidone metabolites |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL126590A (en) * | 1996-05-07 | 2001-11-25 | Pfizer | Mesylate trihydrates salt of 5-(2-(4-(1, 2-benzisothiazol-3-yl)-1-piperazinyl) ethyl)-6-chloro-1, 3-dihydro-2(1h)-indol-2-one (=ziprasidone) and pharmaceutical compositions comprising it |
| TW491847B (en) * | 1996-05-07 | 2002-06-21 | Pfizer | Mesylate dihydrate salts of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2h-indol-2-one |
| ES2204067T3 (en) * | 1998-05-26 | 2004-04-16 | Pfizer Products Inc. | MEDICINAL PRODUCT FOR THE TREATMENT OF GLAUCOMA AND ISCHEMICAL RETINOPATHY. |
-
2001
- 2001-05-28 AU AU2001258690A patent/AU2001258690A1/en not_active Abandoned
- 2001-05-28 WO PCT/IB2001/000933 patent/WO2001091756A2/en not_active Ceased
- 2001-05-28 MX MXPA02011862A patent/MXPA02011862A/en active IP Right Grant
- 2001-05-28 UA UA2002119557A patent/UA79425C2/en unknown
- 2001-05-28 KR KR1020027016364A patent/KR20030007824A/en not_active Ceased
- 2001-05-28 JP JP2001587771A patent/JP2003534381A/en not_active Withdrawn
- 2001-05-28 ES ES04013380T patent/ES2277170T3/en not_active Expired - Lifetime
- 2001-05-28 SI SI200130681T patent/SI1468686T1/en unknown
- 2001-05-28 DE DE60133596T patent/DE60133596D1/en not_active Expired - Lifetime
- 2001-05-28 PT PT04013380T patent/PT1468686E/en unknown
- 2001-05-28 GE GE4972A patent/GEP20053512B/en unknown
- 2001-05-28 EP EP01932011A patent/EP1286672B1/en not_active Expired - Lifetime
- 2001-05-28 PT PT06116051T patent/PT1698338E/en unknown
- 2001-05-28 PL PL01365576A patent/PL365576A1/en unknown
- 2001-05-28 IL IL15278201A patent/IL152782A0/en active IP Right Grant
- 2001-05-28 EE EEP200200670A patent/EE200200670A/en unknown
- 2001-05-28 SK SK1662-2002A patent/SK16622002A3/en not_active Application Discontinuation
- 2001-05-28 DE DE60124791T patent/DE60124791T2/en not_active Expired - Fee Related
- 2001-05-28 CN CN01810620A patent/CN1431901A/en active Pending
- 2001-05-28 EP EP06116051A patent/EP1698338B1/en not_active Expired - Lifetime
- 2001-05-28 EP EP04013380A patent/EP1468686B1/en not_active Expired - Lifetime
- 2001-05-28 OA OA1200200349A patent/OA12267A/en unknown
- 2001-05-28 AT AT01932011T patent/ATE343387T1/en not_active IP Right Cessation
- 2001-05-28 BR BR0111271-6A patent/BR0111271A/en not_active Application Discontinuation
- 2001-05-28 DK DK04013380T patent/DK1468686T3/en active
- 2001-05-28 NZ NZ551012A patent/NZ551012A/en unknown
- 2001-05-28 AT AT06116051T patent/ATE391507T1/en not_active IP Right Cessation
- 2001-05-28 HR HR20020953A patent/HRP20020953A2/en not_active Application Discontinuation
- 2001-05-28 CA CA002410618A patent/CA2410618A1/en not_active Abandoned
- 2001-05-28 AT AT04013380T patent/ATE345818T1/en not_active IP Right Cessation
- 2001-05-28 CZ CZ20023860A patent/CZ20023860A3/en unknown
- 2001-05-28 EA EA200201168A patent/EA007068B1/en not_active IP Right Cessation
- 2001-05-28 YU YU90702A patent/YU90702A/en unknown
- 2001-05-28 DE DE60124093T patent/DE60124093D1/en not_active Expired - Lifetime
- 2001-05-28 HU HU0301747A patent/HUP0301747A2/en unknown
- 2001-05-31 DO DO2001000181A patent/DOP2001000181A/en unknown
- 2001-05-31 UY UY26742A patent/UY26742A1/en not_active Application Discontinuation
- 2001-05-31 AP APAP/P/2001/002180A patent/AP1831A/en active
- 2001-05-31 HN HN2001000119A patent/HN2001000119A/en unknown
- 2001-05-31 PE PE2001000504A patent/PE20011329A1/en not_active Application Discontinuation
- 2001-05-31 AP AP2005003272A patent/AP1747A/en active
- 2001-06-01 PA PA20018518301A patent/PA8518301A1/en unknown
- 2001-06-01 AR ARP010102641A patent/AR028937A1/en unknown
- 2001-06-01 SV SV2001000473A patent/SV2002000473A/en not_active Application Discontinuation
- 2001-06-04 US US09/873,973 patent/US20060287336A1/en not_active Abandoned
-
2002
- 2002-11-11 IL IL152782A patent/IL152782A/en not_active IP Right Cessation
- 2002-11-12 BG BG107267A patent/BG107267A/en unknown
- 2002-11-14 IS IS6619A patent/IS6619A/en unknown
- 2002-11-28 ZA ZA200209665A patent/ZA200209665B/en unknown
- 2002-11-29 MA MA26927A patent/MA26908A1/en unknown
- 2002-11-29 NO NO20025760A patent/NO325077B1/en unknown
- 2002-11-29 EC EC2002004369A patent/ECSP024369A/en unknown
-
2007
- 2007-02-08 CY CY20071100161T patent/CY1105992T1/en unknown
- 2007-11-14 JP JP2007296039A patent/JP2008056700A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000059489A2 (en) * | 1999-04-06 | 2000-10-12 | Sepracor Inc. | Methods and compositions for the treatment of psychotic and related disorders using ziprasidone metabolites |
Non-Patent Citations (4)
| Title |
|---|
| DANIEL D.G. ET AL: "Ziprasidone: Comprehensive overview and clinical use of a novel antipsychotic.", EXPERT OPINION ON INVESTIGATIONAL DRUGS, ( 2000 ) 9/4 (819-828)., XP001041844 * |
| PRAKASH C ET AL.: "Characterization of the novel benzisothiazole ring-cleaved prducts of the antipsychotic drug ziprasidone", DRUG METABOLISM AND DISPOSITION, vol. 25, no. 7, 1997, pages 897 - 901, XP001041808 * |
| PRAKASH C ET AL: "Metabolism and excretion of a new antipsychotic drug, ziprasidone, in humans", DRUG METABOLISM AND DISPOSITION, vol. 25, no. 7, 1997, pages 863 - 872, XP001041807 * |
| PRAKASH C ET AL: "Metabolism and excretion of the novel antipsychotic drug ziprasidone in rats after oral administration of a mixture of 14C- and 3H-labeled ziprasidone", DRUG METABOLISM AND DISPOSITION, vol. 25, no. 1, 1997, pages 206 - 218, XP001041804 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7667037B2 (en) | 2003-10-24 | 2010-02-23 | Teva Pharmaceutical Industries Ltd. | Processes for preparation of ziprasidone |
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