WO2002012237A3 - Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones - Google Patents

Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones Download PDF

Info

Publication number
WO2002012237A3
WO2002012237A3 PCT/US2001/022001 US0122001W WO0212237A3 WO 2002012237 A3 WO2002012237 A3 WO 2002012237A3 US 0122001 W US0122001 W US 0122001W WO 0212237 A3 WO0212237 A3 WO 0212237A3
Authority
WO
WIPO (PCT)
Prior art keywords
pyrido
preparing
dialkyloxyphenyl
pyrimidin
pyridyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/022001
Other languages
French (fr)
Other versions
WO2002012237A2 (en
Inventor
Vladimir Genukh Beylin
Richard Jungkyu Lee
Mark Eugene Marlatt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Priority to AU2001278908A priority Critical patent/AU2001278908A1/en
Priority to US10/343,805 priority patent/US6960662B2/en
Priority to JP2002518212A priority patent/JP2004505974A/en
Priority to BR0112861-2A priority patent/BR0112861A/en
Priority to EP01957137A priority patent/EP1307451A2/en
Priority to MXPA03000289A priority patent/MXPA03000289A/en
Priority to CA002417937A priority patent/CA2417937A1/en
Publication of WO2002012237A2 publication Critical patent/WO2002012237A2/en
Publication of WO2002012237A3 publication Critical patent/WO2002012237A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Process for preparing 2-pyridylamino-pyrido[2,3-d]pyrimidines of Formula (II) wherein Ar is aryl, R' and R'' are hydrogen, alkyl, alkoxy, or phenyl, and R2 is alkyl.
PCT/US2001/022001 2000-08-04 2001-07-12 Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones Ceased WO2002012237A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AU2001278908A AU2001278908A1 (en) 2000-08-04 2001-07-12 Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido(2,3-d)pyrimidin 7-ones
US10/343,805 US6960662B2 (en) 2000-08-04 2001-07-12 Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones
JP2002518212A JP2004505974A (en) 2000-08-04 2001-07-12 Method for producing 2- (4-pyridyl) amino-6-dialkyloxyphenylpyrido [2,3-d] pyrimidin-7-one
BR0112861-2A BR0112861A (en) 2000-08-04 2001-07-12 Process for the preparation of 2- (4-pyridyl) amino-6-dialkyloxyphenyl-pyrido [2,3-d] pyrimidin-7-ones
EP01957137A EP1307451A2 (en) 2000-08-04 2001-07-12 Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido 2,3-d]pyrimidin-7-ones
MXPA03000289A MXPA03000289A (en) 2000-08-04 2001-07-12 Process for preparing 2-(4-pyridyl) amino-6 -dialkyloxyphenyl -pyrido[2,3-d] pyrimidin -7-ones.
CA002417937A CA2417937A1 (en) 2000-08-04 2001-07-12 Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22308400P 2000-08-04 2000-08-04
US60/223,084 2000-08-04

Publications (2)

Publication Number Publication Date
WO2002012237A2 WO2002012237A2 (en) 2002-02-14
WO2002012237A3 true WO2002012237A3 (en) 2002-05-10

Family

ID=22834962

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/022001 Ceased WO2002012237A2 (en) 2000-08-04 2001-07-12 Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones

Country Status (9)

Country Link
US (1) US6960662B2 (en)
EP (1) EP1307451A2 (en)
JP (1) JP2004505974A (en)
AR (1) AR030571A1 (en)
AU (1) AU2001278908A1 (en)
BR (1) BR0112861A (en)
CA (1) CA2417937A1 (en)
MX (1) MXPA03000289A (en)
WO (1) WO2002012237A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022711B2 (en) * 2000-08-04 2006-04-04 Warner-Lambert Company 2-(4-Pyridyl)amino-6-dialkoxyphenyl-pyrido[2,3-d]pyrimidin-7-ones
ATE303385T1 (en) * 2000-08-04 2005-09-15 Warner Lambert Co METHOD FOR PRODUCING 2-(4-PYRIDYL)AMINO-6-DIALKYLOLXAPHENYL-PYRIDO(2,3-D)PYRIMIDONE-7-ONE DERIVATIVES
US7196090B2 (en) * 2002-07-25 2007-03-27 Warner-Lambert Company Kinase inhibitors
US7098332B2 (en) 2002-12-20 2006-08-29 Hoffmann-La Roche Inc. 5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones
GB0230019D0 (en) * 2002-12-23 2003-01-29 Syngenta Ltd Fungicides
BRPI0507852A (en) * 2004-02-18 2007-07-10 Warner Lambert Co 2- (pyridin-3-ylamino) -pyrido [2,3-d] pyrimidin-7-ones

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733914A (en) * 1995-05-03 1998-03-31 Warner-Lambert Company Pyrido 2, 3-d!pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1336904C (en) 1987-08-26 1995-09-05 Mitsuyuki Takesue Pyrimidines and their pharmaceutically acceptable salts thereof
DE4408404A1 (en) 1994-03-12 1995-09-14 Huels Chemische Werke Ag Process for the preparation of chloropyrimidines
US5801183A (en) 1995-01-27 1998-09-01 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Aza and aza (N-oxy) analogs of glycine/NMDA receptor antagonists
IL117923A (en) 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
US5945422A (en) * 1997-02-05 1999-08-31 Warner-Lambert Company N-oxides of amino containing pyrido 2,3-D! pyrimidines
RO120911B1 (en) 1998-03-13 2006-09-29 Novartis Ag 3-hydroxy-4-aryl-5-oxopiralozine derivatives, active as herbicides
US6855726B1 (en) 1998-03-31 2005-02-15 Warner-Lambert Company Llc Quinolones as serine protease inhibitors
US7022711B2 (en) * 2000-08-04 2006-04-04 Warner-Lambert Company 2-(4-Pyridyl)amino-6-dialkoxyphenyl-pyrido[2,3-d]pyrimidin-7-ones
ATE303385T1 (en) * 2000-08-04 2005-09-15 Warner Lambert Co METHOD FOR PRODUCING 2-(4-PYRIDYL)AMINO-6-DIALKYLOLXAPHENYL-PYRIDO(2,3-D)PYRIMIDONE-7-ONE DERIVATIVES
MXPA04005939A (en) * 2002-01-22 2005-01-25 Warner Lambert Co 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d]PYRIMIDIN-7-ONES.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733914A (en) * 1995-05-03 1998-03-31 Warner-Lambert Company Pyrido 2, 3-d!pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation

Also Published As

Publication number Publication date
WO2002012237A2 (en) 2002-02-14
AU2001278908A1 (en) 2002-02-18
BR0112861A (en) 2003-07-01
JP2004505974A (en) 2004-02-26
EP1307451A2 (en) 2003-05-07
US20030216415A1 (en) 2003-11-20
US6960662B2 (en) 2005-11-01
MXPA03000289A (en) 2003-06-06
AR030571A1 (en) 2003-08-27
CA2417937A1 (en) 2002-02-14

Similar Documents

Publication Publication Date Title
CA2278331A1 (en) 3-heterocyclyl-substituted benzoyl derivatives
NZ333706A (en) Benzenesulfone derivatives and medicaments
CA2319005A1 (en) 2-pyridylmethylamine derivatives useful as fungicides
WO2001009103A3 (en) Imidazole antiproliferative agents
HUT76657A (en) 2-(1',2',4'-triazol-3'-yloxymethylene)-anilides, process for producing them and their use as pestcontrol agents
CA2301093A1 (en) Fluoropyrazole-biphenylamide fungicides
TWI349674B (en) Derivatives of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl]phosphonic acid and methods of use thereof
AU3744397A (en) Total synthesis of antitumor acylfulvenes
WO2001034601A3 (en) Imidazopyridine derivatives as phosphodiesterase vii inhibitors
WO2001036425A3 (en) Imidazole compounds used as phosphodiesterase vii inhibitors
WO2000005214A3 (en) Isoquinolines as urokinase inhibitors
WO2005063786A3 (en) Process for fluorocytidine derivatives
CA2452036A1 (en) 6-'2-(phosphonomethoxy) alkoxy pyrimidine derivatives having antiviral activity
WO2002012237A3 (en) Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones
WO2003027110A3 (en) Process for preparing 2-(4-pyridyl) amino-6-dialkyloxyphenyl-pyrido [2,3-d]pyrimidin-7-ones
WO2000046210A3 (en) New process for preparing pesticidal intermediates
WO2003024400A3 (en) Process for the preparation of 1,5-diarylpyrazoles
WO2001053275A3 (en) Substituted aryl ketones
AU8631698A (en) A process for the preparation of tetraazamacrocycles
UA80839C2 (en) 1-substituted 4-nitroimidazole compound and process for producing the same
BG106784A (en) 3-(4,5-dihydroisoxalole-5-yl)benzoylpyrazole
AU6876896A (en) Carbamoylcarboxamides
BG104037A (en) 6-pyrrolidin-2-ylpyrindine derivatives, their preparation and application in therapy
HK1042288A1 (en) 6-((aryl and heteroaryl)oxy)methyl)naphthalene-2-carboximidamide derivatives, preparation and therapeutic application thereof
AU2406700A (en) 3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl(3-(1h-indol-3-yl)-a kyl)-amines

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: PA/a/2003/000289

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 2001957137

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2417937

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2002518212

Country of ref document: JP

Ref document number: 10343805

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 2001957137

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642