WO2002016944A3 - Synthetic nucleic acid molecule compositions and methods of preparation - Google Patents
Synthetic nucleic acid molecule compositions and methods of preparation Download PDFInfo
- Publication number
- WO2002016944A3 WO2002016944A3 PCT/US2001/026566 US0126566W WO0216944A3 WO 2002016944 A3 WO2002016944 A3 WO 2002016944A3 US 0126566 W US0126566 W US 0126566W WO 0216944 A3 WO0216944 A3 WO 0216944A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acid
- synthetic nucleic
- preparation
- methods
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Abstract
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE60140898T DE60140898D1 (en) | 2000-08-24 | 2001-08-24 | SYNTHETIC NUCLEIC ACID MOLECULE COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF |
| AT01964425T ATE452905T1 (en) | 2000-08-24 | 2001-08-24 | SYNTHETIC NUCLEIC ACID MOLECULE COMPOSITIONS AND METHODS FOR THEIR PRODUCTION |
| JP2002521985A JP2004520807A (en) | 2000-08-24 | 2001-08-24 | Synthetic nucleic acid molecule composition and preparation method |
| CA002420328A CA2420328A1 (en) | 2000-08-24 | 2001-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
| DK01964425.1T DK1341808T3 (en) | 2000-08-24 | 2001-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
| AU2001285278A AU2001285278B2 (en) | 2000-08-24 | 2001-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
| EP01964425A EP1341808B1 (en) | 2000-08-24 | 2001-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
| AU8527801A AU8527801A (en) | 2000-08-24 | 2001-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/645,706 US7879540B1 (en) | 2000-08-24 | 2000-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
| US09/645,706 | 2000-08-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2002016944A2 WO2002016944A2 (en) | 2002-02-28 |
| WO2002016944A3 true WO2002016944A3 (en) | 2003-06-26 |
Family
ID=24590123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2001/026566 Ceased WO2002016944A2 (en) | 2000-08-24 | 2001-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US7879540B1 (en) |
| EP (1) | EP1341808B1 (en) |
| JP (3) | JP2004520807A (en) |
| AT (1) | ATE452905T1 (en) |
| AU (2) | AU2001285278B2 (en) |
| CA (1) | CA2420328A1 (en) |
| DE (1) | DE60140898D1 (en) |
| DK (1) | DK1341808T3 (en) |
| ES (1) | ES2335268T3 (en) |
| WO (1) | WO2002016944A2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9487520B2 (en) | 2010-11-02 | 2016-11-08 | Promega Corporation | Coelenterazine derivatives and methods of using same |
Families Citing this family (61)
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|---|---|---|---|---|
| US6602677B1 (en) * | 1997-09-19 | 2003-08-05 | Promega Corporation | Thermostable luciferases and methods of production |
| US7879540B1 (en) | 2000-08-24 | 2011-02-01 | Promega Corporation | Synthetic nucleic acid molecule compositions and methods of preparation |
| US20030157643A1 (en) * | 2000-08-24 | 2003-08-21 | Almond Brian D | Synthetic nucleic acids from aquatic species |
| US7413874B2 (en) | 2002-12-09 | 2008-08-19 | University Of Miami | Nucleic acid encoding fluorescent proteins from aquatic species |
| CN1784496B (en) * | 2003-05-06 | 2010-08-25 | 独立行政法人产业技术综合研究所 | Multi-gene transcription activity assay system |
| US20070077563A1 (en) * | 2003-08-29 | 2007-04-05 | Takara Bio Inc. | Method of searching for functional nucleotide molecule |
| EP2308978B8 (en) | 2003-10-10 | 2015-04-08 | Promega Corporation | Luciferase biosensor |
| WO2006046132A2 (en) * | 2004-09-17 | 2006-05-04 | Institut Pasteur | Method for modulating the evolution of a polypeptide encoded by a nucleic acid sequence |
| US7728118B2 (en) | 2004-09-17 | 2010-06-01 | Promega Corporation | Synthetic nucleic acid molecule compositions and methods of preparation |
| WO2007030473A2 (en) * | 2005-09-06 | 2007-03-15 | Stanford University | Luciferases and methods for making and using the same |
| WO2007058140A1 (en) | 2005-11-16 | 2007-05-24 | Toyo Boseki Kabushiki Kaisha | Luciferase gene optimized for use in imaging of intracellular luminescence |
| EP2004813B1 (en) | 2006-04-03 | 2015-06-03 | Promega Corporation | Permuted and nonpermuted luciferase biosensors binding cyclic nucleotides |
| WO2007139584A2 (en) * | 2006-05-25 | 2007-12-06 | Institute For Advanced Study | Methods for identifying sequence motifs, and applications thereof |
| AU2007345319B2 (en) | 2006-07-13 | 2012-09-06 | Institute For Advanced Study | Viral inhibitory nucleotide sequences and vaccines |
| EP2374875B1 (en) | 2006-10-30 | 2015-09-02 | Promega Corporation | Mutant hydrolase proteins with enhanced kinetics and funcitional expression |
| LT2167540T (en) | 2007-06-29 | 2018-04-25 | F. Hoffmann-La Roche Ag | Heavy chain mutant leading to improved immunoglobulin production |
| JP5258084B2 (en) * | 2008-01-07 | 2013-08-07 | 株式会社ProbeX | Method for detecting protein-protein interaction |
| EP2281046B1 (en) | 2008-05-19 | 2012-01-25 | Promega Corporation | LUCIFERASE BIOSENSORS FOR cAMP |
| JP4849698B2 (en) | 2009-05-29 | 2012-01-11 | 国立大学法人 東京大学 | Sensitive detection method for protein-protein interaction |
| EP3508570B1 (en) | 2010-05-11 | 2020-07-22 | Promega Corporation | Mutant protease biosensors with enhanced detection characteristics |
| US9290794B2 (en) | 2010-05-11 | 2016-03-22 | Promega Corporation | Mutant protease biosensors with enhanced detection characteristics |
| EP2580329B1 (en) * | 2010-06-10 | 2018-07-11 | Active Motif, Inc. | Modified renilla luciferase nucleic acids and methods of use |
| SG10202103336SA (en) | 2010-11-02 | 2021-04-29 | Promega Corp | Novel coelenterazine substrates and methods of use |
| HUE046506T2 (en) | 2011-06-16 | 2020-03-30 | Univ California | Synthetic gene clusters |
| EP2776573A1 (en) | 2011-11-11 | 2014-09-17 | Promega Corporation | Mutant protease biosensors with enhanced detection characteristics |
| EP3597741A1 (en) | 2012-04-27 | 2020-01-22 | Duke University | Genetic correction of mutated genes |
| WO2014071182A1 (en) | 2012-11-01 | 2014-05-08 | Massachusetts Institute Of Technology | Directed evolution of synthetic gene cluster |
| JP6604938B2 (en) | 2013-03-15 | 2019-11-13 | プロメガ コーポレイション | Substrates for covalently anchoring proteins to functional groups or solid surfaces |
| US9828582B2 (en) | 2013-03-19 | 2017-11-28 | Duke University | Compositions and methods for the induction and tuning of gene expression |
| US9790537B2 (en) | 2014-01-29 | 2017-10-17 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| EP3099691B1 (en) | 2014-01-29 | 2019-11-20 | Promega Corporation | Pro-substrates for live cell applications |
| US9732373B2 (en) * | 2014-09-11 | 2017-08-15 | Promega Corporation | Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence |
| US10676726B2 (en) | 2015-02-09 | 2020-06-09 | Duke University | Compositions and methods for epigenome editing |
| CN108602729B (en) | 2015-07-13 | 2022-07-05 | 皮沃特生物公司 | Methods and compositions for improving plant traits |
| WO2017062412A1 (en) | 2015-10-05 | 2017-04-13 | Massachusetts Institute Of Technology | Nitrogen fixation using refactored nif clusters |
| EP4089175A1 (en) | 2015-10-13 | 2022-11-16 | Duke University | Genome engineering with type i crispr systems in eukaryotic cells |
| EA201891317A3 (en) | 2015-11-30 | 2019-04-30 | Дьюк Юниверсити | THERAPEUTIC TARGETS FOR CORRECTION OF HUMAN DISTROPHIN GENE BY EDITING GENES AND METHODS OF THEIR APPLICATION |
| US20190127713A1 (en) | 2016-04-13 | 2019-05-02 | Duke University | Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use |
| WO2018017754A1 (en) | 2016-07-19 | 2018-01-25 | Duke University | Therapeutic applications of cpf1-based genome editing |
| WO2018049241A1 (en) | 2016-09-09 | 2018-03-15 | Promega Corporation | Dual protected pro-coelenterazine substrates |
| JP7234116B2 (en) | 2017-01-12 | 2023-03-07 | ピボット バイオ, インコーポレイテッド | Methods and compositions for improving plant traits |
| JP2021500907A (en) | 2017-10-25 | 2021-01-14 | ピボット バイオ, インコーポレイテッド | Gene target for nitrogen fixation for the purpose of improving plant traits |
| AU2018354221B2 (en) | 2017-10-25 | 2025-04-17 | Pivot Bio, Inc. | Methods and compositions for improving engineered microbes that fix nitrogen |
| CA3022981C (en) | 2017-11-01 | 2025-05-06 | Queen's University At Kingston | Hippo pathway bioluminescent biosensor |
| WO2019144061A1 (en) | 2018-01-19 | 2019-07-25 | Duke University | Genome engineering with crispr-cas systems in eukaryotes |
| CN112739668A (en) | 2018-06-27 | 2021-04-30 | 皮沃特生物股份有限公司 | Agricultural compositions comprising reconstituted nitrogen-fixing microorganisms |
| KR20210060434A (en) | 2018-07-11 | 2021-05-26 | 피벗 바이오, 인크. | Temporal and spatial targeting dynamic nitrogen delivery by remodeled microorganisms |
| WO2020146372A1 (en) | 2019-01-07 | 2020-07-16 | Pivot Bio, Inc. | Plant colonization assays using natural microbial barcodes |
| WO2020185312A2 (en) | 2019-01-25 | 2020-09-17 | President And Fellows Of Harvard College | Compositions and method for synthesizing nucleic acids |
| WO2020190363A1 (en) | 2019-03-19 | 2020-09-24 | Massachusetts Institute Of Technology | Control of nitrogen fixation in rhizobia that associate with cereals |
| EP3990484A1 (en) | 2019-06-28 | 2022-05-04 | F. Hoffmann-La Roche AG | Method for the production of an antibody |
| CN115176027A (en) | 2019-12-12 | 2022-10-11 | 哈佛大学校长及研究员协会 | Compositions and methods for light-directed biomolecular barcoding |
| US20230203567A1 (en) | 2020-04-22 | 2023-06-29 | President And Fellows Of Harvard College | Isothermal methods, compositions, kits, and systems for detecting nucleic acids |
| PY2134250A (en) | 2020-05-01 | 2022-01-28 | Pivot Bio Inc | STABLE LIQUID FORMULATIONS FOR NITROGEN-FIXING MICROORGANISMS |
| AU2020445067A1 (en) | 2020-05-01 | 2022-12-01 | Pivot Bio, Inc. | Measurement of nitrogen fixation and incorporation |
| JP2023545038A (en) | 2020-10-06 | 2023-10-26 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | Methods, compositions, kits, and systems for signal-on detection of neutralizing targets |
| EP4519290A1 (en) | 2022-05-04 | 2025-03-12 | Promega Corporation | Circularly permuted dehalogenase variants |
| WO2023215505A1 (en) | 2022-05-04 | 2023-11-09 | Promega Corporation | Modified dehalogenase with extended surface loop regions |
| WO2023215452A2 (en) | 2022-05-04 | 2023-11-09 | Promega Corporation | Split modified dehalogenase variants |
| IL317874A (en) | 2022-06-24 | 2025-02-01 | Tune Therapeutics Inc | Compositions, systems, and methods for reducing low-density lipoprotein through targeted gene repression |
| EP4729632A1 (en) | 2024-10-18 | 2026-04-22 | AskBio Inc. | Method of synthesizing dna |
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-
2000
- 2000-08-24 US US09/645,706 patent/US7879540B1/en not_active Expired - Fee Related
-
2001
- 2001-08-24 WO PCT/US2001/026566 patent/WO2002016944A2/en not_active Ceased
- 2001-08-24 AU AU2001285278A patent/AU2001285278B2/en not_active Ceased
- 2001-08-24 JP JP2002521985A patent/JP2004520807A/en active Pending
- 2001-08-24 AT AT01964425T patent/ATE452905T1/en not_active IP Right Cessation
- 2001-08-24 AU AU8527801A patent/AU8527801A/en active Pending
- 2001-08-24 EP EP01964425A patent/EP1341808B1/en not_active Expired - Lifetime
- 2001-08-24 DK DK01964425.1T patent/DK1341808T3/en active
- 2001-08-24 ES ES01964425T patent/ES2335268T3/en not_active Expired - Lifetime
- 2001-08-24 DE DE60140898T patent/DE60140898D1/en not_active Expired - Lifetime
- 2001-08-24 CA CA002420328A patent/CA2420328A1/en not_active Abandoned
-
2005
- 2005-12-22 US US11/316,042 patent/US20060127988A1/en not_active Abandoned
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2006
- 2006-10-23 JP JP2006288147A patent/JP2007006910A/en active Pending
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2007
- 2007-04-12 US US11/786,785 patent/US7906282B2/en not_active Expired - Fee Related
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2010
- 2010-01-18 JP JP2010008451A patent/JP2010081942A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995018853A1 (en) * | 1994-01-03 | 1995-07-13 | Promega Corporation | Mutant luciferases |
| US5670356A (en) * | 1994-12-12 | 1997-09-23 | Promega Corporation | Modified luciferase |
| WO1999014336A2 (en) * | 1997-09-19 | 1999-03-25 | Promega Corporation | Thermostable luciferases and methods of production |
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| DATABASE EBI [online] 8 August 2000 (2000-08-08), FERBITZ L. ET AL.: "A synthetic gene coding for Renilla luciferase is a versatile expression marker in green algae", XP002230923, Database accession no. AY004213 * |
| KIM C.H. ET AL.: "Codon optimization for high-level expression of human erythropoietin (EPO) in mammalian cells", GENE, vol. 199, no. 1-2, 15 October 1997 (1997-10-15), pages 293 - 301, XP004126394, ISSN: 0378-1119 * |
| PAN W. ET AL.: "Vaccine candidate MSP-1 from Plasmodium falciparum: a redesigned 4917 bp polynucleotide enables synthesis and isolation of full-length protein from Escherichia coli and mammalian cells", NUCLEIC ACIDS RESEARCH, vol. 27, no. 4, 15 February 1999 (1999-02-15), pages 1094 - 1103, XP000953100, ISSN: 0305-1048 * |
| WOOD K.V.: "The chemical mechanism and evolutionary development of beetle bioluminescence", PHOTOCHEMISTRY AND PHOTOBIOLOGY, vol. 62, no. 4, 1995, pages 662 - 673, XP000983576, ISSN: 0031-8655 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9487520B2 (en) | 2010-11-02 | 2016-11-08 | Promega Corporation | Coelenterazine derivatives and methods of using same |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE452905T1 (en) | 2010-01-15 |
| US7906282B2 (en) | 2011-03-15 |
| DE60140898D1 (en) | 2010-02-04 |
| DK1341808T3 (en) | 2010-04-12 |
| US20080090291A1 (en) | 2008-04-17 |
| AU2001285278B2 (en) | 2008-05-08 |
| CA2420328A1 (en) | 2002-02-28 |
| ES2335268T3 (en) | 2010-03-24 |
| JP2007006910A (en) | 2007-01-18 |
| EP1341808A2 (en) | 2003-09-10 |
| JP2010081942A (en) | 2010-04-15 |
| WO2002016944A2 (en) | 2002-02-28 |
| US7879540B1 (en) | 2011-02-01 |
| JP2004520807A (en) | 2004-07-15 |
| EP1341808B1 (en) | 2009-12-23 |
| AU8527801A (en) | 2002-03-04 |
| US20060127988A1 (en) | 2006-06-15 |
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