WO2002022821A3 - Antimicrobial peptides and methods of use - Google Patents

Antimicrobial peptides and methods of use Download PDF

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Publication number
WO2002022821A3
WO2002022821A3 PCT/US2001/028429 US0128429W WO0222821A3 WO 2002022821 A3 WO2002022821 A3 WO 2002022821A3 US 0128429 W US0128429 W US 0128429W WO 0222821 A3 WO0222821 A3 WO 0222821A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
kcp
antimicrobial peptides
plants
rprovides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/028429
Other languages
French (fr)
Other versions
WO2002022821A2 (en
Inventor
Carl R Simmons
Acevedo Pedro A Navarro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pioneer Hi Bred International Inc
Original Assignee
Pioneer Hi Bred International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pioneer Hi Bred International Inc filed Critical Pioneer Hi Bred International Inc
Priority to MXPA03002218A priority Critical patent/MXPA03002218A/en
Priority to AU9078401A priority patent/AU9078401A/en
Priority to EP01970822A priority patent/EP1379658B1/en
Priority to CA002422041A priority patent/CA2422041A1/en
Priority to DE60137587T priority patent/DE60137587D1/en
Priority to BR0113864-2A priority patent/BR0113864A/en
Priority to AU2001290784A priority patent/AU2001290784B2/en
Publication of WO2002022821A2 publication Critical patent/WO2002022821A2/en
Anticipated expiration legal-status Critical
Publication of WO2002022821A3 publication Critical patent/WO2002022821A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The invention provides isolated KCP-like nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering KCP-like nucleic acid and/or protein concentration and/or composition of plants. The invention furthe rprovides recombinant expression cassettes, host cells, and transgenic plants.
PCT/US2001/028429 2000-09-13 2001-09-13 Antimicrobial peptides and methods of use Ceased WO2002022821A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
MXPA03002218A MXPA03002218A (en) 2000-09-13 2001-09-13 Antimicrobial peptides and methods of use.
AU9078401A AU9078401A (en) 2000-09-13 2001-09-13 Antimicrobial peptides and methods of use
EP01970822A EP1379658B1 (en) 2000-09-13 2001-09-13 Antimicrobial peptides and methods of use
CA002422041A CA2422041A1 (en) 2000-09-13 2001-09-13 Antimicrobial peptides and methods of use
DE60137587T DE60137587D1 (en) 2000-09-13 2001-09-13 ANTIMICROBIAL PEPTIDES AND THEIR USE
BR0113864-2A BR0113864A (en) 2000-09-13 2001-09-13 isolated kcp-type nucleic acids and their encoded proteins
AU2001290784A AU2001290784B2 (en) 2000-09-13 2001-09-13 Antimicrobial peptides and methods of use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23256900P 2000-09-13 2000-09-13
US60/232,569 2000-09-13
US09/950,933 2001-09-11
US09/950,933 US6875907B2 (en) 2000-09-13 2001-09-11 Antimicrobial peptides and methods of use

Publications (2)

Publication Number Publication Date
WO2002022821A2 WO2002022821A2 (en) 2002-03-21
WO2002022821A3 true WO2002022821A3 (en) 2003-10-30

Family

ID=26926132

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/028429 Ceased WO2002022821A2 (en) 2000-09-13 2001-09-13 Antimicrobial peptides and methods of use

Country Status (9)

Country Link
US (5) US6875907B2 (en)
EP (2) EP2039769A3 (en)
AT (1) ATE421992T1 (en)
AU (2) AU9078401A (en)
BR (1) BR0113864A (en)
CA (1) CA2422041A1 (en)
DE (1) DE60137587D1 (en)
MX (1) MXPA03002218A (en)
WO (1) WO2002022821A2 (en)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030022359A1 (en) * 2000-06-20 2003-01-30 Sayre Richard T. Transgenic algae for delivering antigens to an animal
US6932980B1 (en) * 2001-01-18 2005-08-23 Richard Sayre Method of making microalgal-based animal foodstuff supplements, microalgal-supplemented animal foodstuffs and method of animal nutrition
CA2492544A1 (en) * 2002-08-02 2004-02-12 Basf Plant Science Gmbh Modification of seed oil by the expression of a putative cytidyltransferase in transgenic plants
WO2006085966A2 (en) * 2004-06-30 2006-08-17 Pioneer Hi-Bred International, Inc. Methods of protecting plants from pathogenic fungi and nematodes
US7978669B2 (en) * 2007-05-09 2011-07-12 Cisco Technology, Inc. Methods and apparatus for efficient MPEG transmission over 802.11
US7947877B2 (en) 2008-05-14 2011-05-24 Monosanto Technology LLC Plants and seeds of spring canola variety SCV328921
US7935870B2 (en) 2008-05-14 2011-05-03 Monsanto Technology Llc Plants and seeds of spring canola variety SCV354718
US7964774B2 (en) 2008-05-14 2011-06-21 Monsanto Technology Llc Plants and seeds of spring canola variety SCV384196
US8829282B2 (en) 2008-05-14 2014-09-09 Monsanto Technology, Llc Plants and seeds of spring canola variety SCV425044
WO2010008737A2 (en) * 2008-06-17 2010-01-21 Pelican Group Holdings, Inc. Antimicrobial fluid handling devices and methods of manufacture
US8403899B2 (en) * 2008-07-08 2013-03-26 Monarch Labs Llc Maggot debridement therapy dressings and methods
US20100184684A1 (en) * 2009-01-06 2010-07-22 C3 Jian, Inc. Antibacterial and antifungal peptides
US20100183523A1 (en) 2009-01-22 2010-07-22 Wagner Richard E Dental composition and method
EP2210582B1 (en) 2009-01-22 2019-09-18 Solarvest Bioenergy Inc. Dental composition comprising algae and method for producing thereof
US8071848B2 (en) 2009-06-17 2011-12-06 Monsanto Technology Llc Plants and seeds of spring canola variety SCV218328
US8440891B2 (en) 2009-09-22 2013-05-14 Board of Trustees of the University of Akransas, N.A. Rice cultivar CL 142-AR
US8440892B2 (en) 2009-10-15 2013-05-14 Board Of Trustees Of The University Of Arkansas, N.A. Rice cultivar CL 181-AR
US8138394B2 (en) 2010-02-26 2012-03-20 Monsanto Technology Llc Plants and seeds of spring canola variety SCV431158
US8148611B2 (en) 2010-02-26 2012-04-03 Monsanto Technology Llc Plants and seeds of spring canola variety SCV453784
US8143488B2 (en) 2010-02-26 2012-03-27 Monsanto Technoloy LLC Plants and seeds of spring canola variety SCV470336
US8581048B2 (en) 2010-03-09 2013-11-12 Monsanto Technology, Llc Plants and seeds of spring canola variety SCV119103
US8153865B2 (en) 2010-03-11 2012-04-10 Monsanto Technology Llc Plants and seeds of spring canola variety SCV152154
US8513487B2 (en) 2011-04-07 2013-08-20 Zenon LISIECZKO Plants and seeds of spring canola variety ND-662c
US8513494B2 (en) 2011-04-08 2013-08-20 Chunren Wu Plants and seeds of spring canola variety SCV695971
US8507761B2 (en) 2011-05-05 2013-08-13 Teresa Huskowska Plants and seeds of spring canola variety SCV372145
US8513495B2 (en) 2011-05-10 2013-08-20 Dale Burns Plants and seeds of spring canola variety SCV291489
US8785729B2 (en) 2011-08-09 2014-07-22 Nunhems, B.V. Lettuce variety redglace
US8754293B2 (en) 2011-09-09 2014-06-17 Nunhems B.V. Lettuce variety intred
WO2013039861A2 (en) 2011-09-12 2013-03-21 modeRNA Therapeutics Engineered nucleic acids and methods of use thereof
US9380756B2 (en) 2012-01-04 2016-07-05 Nunhems B.V. Lettuce variety multigreen 50
CN104411338A (en) 2012-04-02 2015-03-11 现代治疗公司 Modified polynucleotides for the production of biologics and proteins associated with human disease
WO2013151665A2 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins associated with human disease
US8802935B2 (en) 2012-04-26 2014-08-12 Monsanto Technology Llc Plants and seeds of spring canola variety SCV942568
US8878009B2 (en) 2012-04-26 2014-11-04 Monsanto Technology, LLP Plants and seeds of spring canola variety SCV318181
US8859857B2 (en) 2012-04-26 2014-10-14 Monsanto Technology Llc Plants and seeds of spring canola variety SCV259778
US8835720B2 (en) 2012-04-26 2014-09-16 Monsanto Technology Llc Plants and seeds of spring canola variety SCV967592
CA2962951A1 (en) 2014-10-01 2016-04-07 Plant Health Care, Inc. Hypersensitive response elicitor peptides and use thereof
KR20170080579A (en) 2014-10-01 2017-07-10 플랜트 헬스 케어, 인코포레이티드 Elicitor peptides having disrupted hypersensitive response box and use thereof
DK3341483T3 (en) 2015-08-28 2020-03-16 Pioneer Hi Bred Int OCHROBACTRUM-MEDIATED TRANSFORMATION OF PLANTS
WO2017083515A2 (en) 2015-11-10 2017-05-18 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
US11371011B2 (en) 2016-04-06 2022-06-28 Plant Health Care, Inc. Beneficial microbes for delivery of effector peptides or proteins and use thereof
PL3439682T3 (en) 2016-04-06 2025-12-01 Plant Health Care, Inc. Hypersensitive response elicitor-derived peptides and use thereof
CN105968177B (en) * 2016-05-06 2021-06-18 广州大学 New application of banana antimicrobial peptide MaSN2 and its gene
CN106632628A (en) * 2016-09-21 2017-05-10 东北师范大学 Plant antiviral related protein GmSN1, and coding gene and application thereof
JP7303110B2 (en) 2017-01-18 2023-07-04 ビステラ， インコーポレイテッド Antibody molecule-drug conjugates and uses thereof
CA3062852A1 (en) 2017-05-11 2018-11-15 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Antimicrobial peptides with alpha-core helices
KR20240085798A (en) 2020-04-03 2024-06-17 비스테라, 인크. Antibody molecule-drug conjugates and uses thereof
EP4725303A1 (en) 2024-10-11 2026-04-15 Agrokray Limited Liability Company Spelt, method of producing spelt plants, grain produced from spelt plant and food product produced therefrom

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021699A1 (en) * 1991-06-07 1992-12-10 Zeneca Limited Biocidal proteins
WO1994011511A1 (en) * 1992-11-12 1994-05-26 Zeneca Limited Biocidal chitin binding proteins
US5932713A (en) * 1995-02-21 1999-08-03 Toyo Boseki Kabushiki Kaisha Cotton fiber tissue-specific genes

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
NZ201918A (en) 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
JPS62291904A (en) 1986-06-12 1987-12-18 Namiki Precision Jewel Co Ltd Mafufacture of permanent magnet
US4873192A (en) 1987-02-17 1989-10-10 The United States Of America As Represented By The Department Of Health And Human Services Process for site specific mutagenesis without phenotypic selection
US5256648A (en) 1988-01-21 1993-10-26 Yale University Selective inhibition of gene expression by photoactivatable oligonucleotides
US5316931A (en) 1988-02-26 1994-05-31 Biosource Genetics Corp. Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
US5990387A (en) 1988-06-10 1999-11-23 Pioneer Hi-Bred International, Inc. Stable transformation of plant cells
US5231020A (en) 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5034323A (en) 1989-03-30 1991-07-23 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5322783A (en) 1989-10-17 1994-06-21 Pioneer Hi-Bred International, Inc. Soybean transformation by microparticle bombardment
US5681941A (en) 1990-01-11 1997-10-28 Isis Pharmaceuticals, Inc. Substituted purines and oligonucleotide cross-linking
US5667976A (en) 1990-05-11 1997-09-16 Becton Dickinson And Company Solid supports for nucleic acid hybridization assays
ATE182468T1 (en) 1990-05-24 1999-08-15 Us Commerce BISTRIAZENES AS CHEMOTHERAPEUTIC AGENTS
US5932782A (en) 1990-11-14 1999-08-03 Pioneer Hi-Bred International, Inc. Plant transformation method using agrobacterium species adhered to microprojectiles
NZ239977A (en) 1990-11-14 1993-08-26 Pioneer Hi Bred Int Transforming plants by the use of agrobacterium
US5484908A (en) 1991-11-26 1996-01-16 Gilead Sciences, Inc. Oligonucleotides containing 5-propynyl pyrimidines
TW261517B (en) 1991-11-29 1995-11-01 Mitsubishi Shozi Kk
US5543507A (en) 1992-03-05 1996-08-06 Isis Pharmaceuticals, Inc. Covalently cross-linked oligonucleotides
US5428148A (en) 1992-04-24 1995-06-27 Beckman Instruments, Inc. N4 - acylated cytidinyl compounds useful in oligonucleotide synthesis
IL108241A (en) 1992-12-30 2000-08-13 Biosource Genetics Corp Plant expression system comprising a defective tobamovirus replicon integrated into the plant chromosome and a helper virus
US6069298A (en) * 1993-02-05 2000-05-30 Regents Of The University Of Minnesota Methods and an acetyl CoA carboxylase gene for conferring herbicide tolerance and an alteration in oil content of plants
US5482685A (en) 1993-04-12 1996-01-09 Matsushita Electric Industrial Co., Ltd. Deodorizing apparatus
US5470722A (en) 1993-05-06 1995-11-28 University Of Iowa Research Foundation Method for the amplification of unknown flanking DNA sequence
US5847047A (en) 1993-06-22 1998-12-08 E. I. Du Pont De Nemours And Company Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type
US5482845A (en) 1993-09-24 1996-01-09 The Trustees Of Columbia University In The City Of New York Method for construction of normalized cDNA libraries
US5470353A (en) 1993-10-20 1995-11-28 Hollister Incorporated Post-operative thermal blanket
DE733059T1 (en) 1993-12-09 1997-08-28 Univ Jefferson CONNECTIONS AND METHOD FOR LOCATION-SPECIFIC MUTATION IN EUKARYOTIC CELLS
US5750868A (en) 1994-12-08 1998-05-12 Pioneer Hi-Bred International, Inc. Reversible nuclear genetic system for male sterility in transgenic plants
US5549551A (en) 1994-12-22 1996-08-27 Advanced Cardiovascular Systems, Inc. Adjustable length balloon catheter
FR2733762B1 (en) 1995-05-02 1997-08-01 Genset Sa METHOD FOR THE SPECIFIC COUPLING OF THE HAIR OF THE 5 'END OF A RNAM FRAGMENT AND PREPARATION OF RNAM AND COMPLETE DNA
US5760012A (en) 1996-05-01 1998-06-02 Thomas Jefferson University Methods and compounds for curing diseases caused by mutations
US5731181A (en) 1996-06-17 1998-03-24 Thomas Jefferson University Chimeric mutational vectors having non-natural nucleotides
DE19620425A1 (en) 1996-05-21 1997-11-27 Nvg Netcard Vermarktungs Gmbh Data carrier card and device for reading / writing the data carrier card in a floppy disk drive
US5986174A (en) 1996-06-21 1999-11-16 Pioneer Hi-Bred International, Inc. Maize promoter sequence for leaf- and stalk-preferred gene expression
US5981840A (en) 1997-01-24 1999-11-09 Pioneer Hi-Bred International, Inc. Methods for agrobacterium-mediated transformation
US6369298B1 (en) 1997-04-30 2002-04-09 Pioneer Hi-Bred International, Inc. Agrobacterium mediated transformation of sorghum
EP0979311A1 (en) 1997-04-30 2000-02-16 Of The University Of Minnesota Regents $i(IN VIVO) USE OF RECOMBINAGENIC OLIGONUCLEOBASES TO CORRECT GENETIC LESIONS IN HEPATOCYTES
US7094606B2 (en) 1997-08-05 2006-08-22 Arntzen Charles J Use of mixed duplex oligonucleotides to effect localized genetic changes in plants
WO1999025821A1 (en) 1997-11-18 1999-05-27 Pioneer Hi-Bred International, Inc. Compositions and methods for genetic modification of plants
EP1056862A1 (en) 1998-02-26 2000-12-06 Pioneer Hi-Bred International, Inc. Family of maize pr-1 genes and promoters
AR014072A1 (en) 1998-02-26 2001-01-31 Pioneer Hi Bred Int ISOLATED NUCLEIC ACID MOLECULA THAT HAS A NUCLEOTIDIC SEQUENCE FOR A PROMOTER THAT IS ABLE TO INITIATE A CONSTITUTIVE TRANSCRIPTION IN A PLANT CELL, CONSTRUCTION DNA, VECTOR, GUEST CELL, METHOD TO EXPRESS IN A NON-SECTIONAL ONE
EP1033405A3 (en) * 1999-02-25 2001-08-01 Ceres Incorporated Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
NL1033850C2 (en) 2007-05-15 2008-11-18 3Force B V Burner system with premixed burners and flame transfer agents.
WO2015170355A1 (en) 2014-05-05 2015-11-12 Filippo Bastianini Apparatus for interrogating distributed optical fibre sensors using a stimulated brillouin scattering optical frequency-domain interferometer
CN105578337A (en) 2014-10-07 2016-05-11 鸿富锦精密工业（深圳）有限公司 Resonant sound equipment

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021699A1 (en) * 1991-06-07 1992-12-10 Zeneca Limited Biocidal proteins
WO1994011511A1 (en) * 1992-11-12 1994-05-26 Zeneca Limited Biocidal chitin binding proteins
US5932713A (en) * 1995-02-21 1999-08-03 Toyo Boseki Kabushiki Kaisha Cotton fiber tissue-specific genes

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EBI Hinxton, UK; 11 August 2000 (2000-08-11), WALBOT V: "Maize ESTs from various cDNA libraries sequenced at Stanford University", XP002228602, Database accession no. BE552680 *
DATABASE EMBL [online] EBI Hinxton, UK; 17 January 2000 (2000-01-17), WALBOT V.: "Maize ESTs from various cDNA libraries sequenced at Stanford University", XP002217194, Database accession no. AW288976 *
HERZOG MICHEL ET AL: "GASA, a gibberellin-regulated gene family from Arabidopsis thaliana related to the tomato GAST1 gene.", PLANT MOLECULAR BIOLOGY, vol. 27, no. 4, 1995, pages 743 - 752, XP002217193, ISSN: 0167-4412 *
SEGURA ANA ET AL: "Snakin-1, a peptide from potato that is active against plant pathogens.", MOLECULAR PLANT-MICROBE INTERACTIONS, vol. 12, no. 1, January 1999 (1999-01-01), pages 16 - 23, XP008009348, ISSN: 0894-0282 *

Also Published As

Publication number Publication date
WO2002022821A2 (en) 2002-03-21
US7807876B1 (en) 2010-10-05
AU9078401A (en) 2002-03-26
US7803989B1 (en) 2010-09-28
MXPA03002218A (en) 2004-03-18
US6875907B2 (en) 2005-04-05
BR0113864A (en) 2004-06-29
US20020166141A1 (en) 2002-11-07
US7166769B1 (en) 2007-01-23
AU2001290784B2 (en) 2006-02-16
CA2422041A1 (en) 2002-03-21
EP2039769A2 (en) 2009-03-25
EP2039769A3 (en) 2009-06-17
US7393999B1 (en) 2008-07-01
ATE421992T1 (en) 2009-02-15
EP1379658A2 (en) 2004-01-14
DE60137587D1 (en) 2009-03-19
EP1379658B1 (en) 2009-01-28

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