WO2002024230A1 - Solid preparations - Google Patents

Solid preparations Download PDF

Info

Publication number
WO2002024230A1
WO2002024230A1 PCT/JP2001/008264 JP0108264W WO0224230A1 WO 2002024230 A1 WO2002024230 A1 WO 2002024230A1 JP 0108264 W JP0108264 W JP 0108264W WO 0224230 A1 WO0224230 A1 WO 0224230A1
Authority
WO
WIPO (PCT)
Prior art keywords
solid preparations
active substance
physiologically active
granules
cellulose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2001/008264
Other languages
English (en)
French (fr)
Inventor
Yoshinori Nakano
Shuji Yoneyama
Masashi Ochi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to AU2001288102A priority Critical patent/AU2001288102A1/en
Priority to CA002423329A priority patent/CA2423329A1/en
Priority to US10/380,725 priority patent/US20040034039A1/en
Priority to EP01967797A priority patent/EP1319409A4/en
Publication of WO2002024230A1 publication Critical patent/WO2002024230A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PCT/JP2001/008264 2000-09-22 2001-09-21 Solid preparations Ceased WO2002024230A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2001288102A AU2001288102A1 (en) 2000-09-22 2001-09-21 Solid preparations
CA002423329A CA2423329A1 (en) 2000-09-22 2001-09-21 Solid preparations
US10/380,725 US20040034039A1 (en) 2000-09-22 2001-09-21 Solid preparations
EP01967797A EP1319409A4 (en) 2000-09-22 2001-09-21 SOLID PREPARATIONS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000-289345 2000-09-22
JP2000289345 2000-09-22

Publications (1)

Publication Number Publication Date
WO2002024230A1 true WO2002024230A1 (en) 2002-03-28

Family

ID=18772770

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2001/008264 Ceased WO2002024230A1 (en) 2000-09-22 2001-09-21 Solid preparations

Country Status (5)

Country Link
US (1) US20040034039A1 (ja)
EP (1) EP1319409A4 (ja)
AU (1) AU2001288102A1 (ja)
CA (1) CA2423329A1 (ja)
WO (1) WO2002024230A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003064429A1 (en) * 2002-01-30 2003-08-07 Takeda Chemical Industries, Ltd. Thienopyrimidines, process for preparing the same and use thereof

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60234812D1 (de) 2001-01-29 2010-02-04 Shionogi & Co Arzneipräparat, das als wirkstoff 5-methyl-1-phenyl-2-(1h)-pyridon enthält
PT1591446E (pt) 2003-01-29 2013-06-12 Takeda Pharmaceutical Compostos de tienopirimidina e sua utilização
KR100882156B1 (ko) 2003-08-08 2009-02-06 아지노모토 가부시키가이샤 나테글리니드 함유 제제
ES2401769T5 (es) 2003-09-12 2020-07-01 Amgen Inc Formulación de disolución rápida de cinacalcet HCl
CA2755274C (en) * 2009-03-13 2017-02-28 Sahoe Kakuda Tablet and granulated powder containing 6-fluoro-3-hydroxy-2-pyrazinecarboxamide
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995022981A1 (en) * 1994-02-24 1995-08-31 Nippon Chemiphar Co., Ltd. Oral synthetic peptide preparation
WO1997040846A1 (en) * 1996-04-30 1997-11-06 Takeda Chemical Industries, Ltd. COMBINED USE OF GnRH AGONIST AND ANTAGONIST
JPH1045619A (ja) * 1996-07-31 1998-02-17 Kaken Pharmaceut Co Ltd 成長ホルモン分泌促進ペプチド含有経口製剤
WO2000000493A1 (en) * 1998-06-26 2000-01-06 Takeda Chemical Industries, Ltd. Thienopyridine compounds, their production and use
WO2000056739A1 (en) * 1999-03-24 2000-09-28 Takeda Chemical Industries, Ltd. Thienopyrimidine compounds, their production and use
WO2001012193A1 (en) * 1999-08-16 2001-02-22 Schering Aktiengesellschaft Pharmaceutical agent comprising a benzamide derivative as active ingredient

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5921613A (ja) * 1982-07-28 1984-02-03 Takeda Chem Ind Ltd 直腸投与製剤
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
US5155115A (en) * 1991-03-12 1992-10-13 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
TW449600B (en) * 1994-04-19 2001-08-11 Takeda Chemical Industries Ltd Condensed-ring thiophene derivatives, their production and use
DK0801559T3 (da) * 1995-02-08 2002-06-17 Yamanouchi Europ Bv Fremgangsmåde til fremstilling af orale doseringsformer indeholdende et beta-lactam antibiotikum
CA2192283A1 (en) * 1995-12-08 1997-06-09 Nobuhiro Suzuki Prolactin production inhibitory agent
AU2406597A (en) * 1996-04-26 1997-11-19 Takeda Chemical Industries Ltd. Thienopyridine derivatives, their production and use
US6313301B1 (en) * 1997-08-13 2001-11-06 Takeda Chemical Industries, Ltd. Thienopyridine derivatives, their intermediates and production thereof
EP1098636A1 (en) * 1998-07-23 2001-05-16 Novo Nordisk A/S A wet granulation method for preparing a stable pharmaceutical formulation
WO2001078780A1 (en) * 2000-04-13 2001-10-25 Takeda Chemical Industries, Ltd. Preventives/remedies for alzheimer's disease

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995022981A1 (en) * 1994-02-24 1995-08-31 Nippon Chemiphar Co., Ltd. Oral synthetic peptide preparation
WO1997040846A1 (en) * 1996-04-30 1997-11-06 Takeda Chemical Industries, Ltd. COMBINED USE OF GnRH AGONIST AND ANTAGONIST
JPH1045619A (ja) * 1996-07-31 1998-02-17 Kaken Pharmaceut Co Ltd 成長ホルモン分泌促進ペプチド含有経口製剤
WO2000000493A1 (en) * 1998-06-26 2000-01-06 Takeda Chemical Industries, Ltd. Thienopyridine compounds, their production and use
WO2000056739A1 (en) * 1999-03-24 2000-09-28 Takeda Chemical Industries, Ltd. Thienopyrimidine compounds, their production and use
WO2001012193A1 (en) * 1999-08-16 2001-02-22 Schering Aktiengesellschaft Pharmaceutical agent comprising a benzamide derivative as active ingredient

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1319409A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003064429A1 (en) * 2002-01-30 2003-08-07 Takeda Chemical Industries, Ltd. Thienopyrimidines, process for preparing the same and use thereof

Also Published As

Publication number Publication date
EP1319409A1 (en) 2003-06-18
CA2423329A1 (en) 2003-03-20
AU2001288102A1 (en) 2002-04-02
US20040034039A1 (en) 2004-02-19
EP1319409A4 (en) 2006-05-03

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