WO2002024861A3 - Verfahren und vorrichtung zum züchten und/oder behandeln von zellen - Google Patents
Verfahren und vorrichtung zum züchten und/oder behandeln von zellen Download PDFInfo
- Publication number
- WO2002024861A3 WO2002024861A3 PCT/EP2001/009159 EP0109159W WO0224861A3 WO 2002024861 A3 WO2002024861 A3 WO 2002024861A3 EP 0109159 W EP0109159 W EP 0109159W WO 0224861 A3 WO0224861 A3 WO 0224861A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- growing
- cell culture
- treating cells
- culture plate
- bore holes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Rigid containers without fluid transport within
- B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
- B01L3/50853—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates with covers or lids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/24—Gas permeable parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/38—Caps; Covers; Plugs; Pouring means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE50113731T DE50113731D1 (de) | 2000-09-19 | 2001-08-08 | Verfahren und vorrichtung zum züchten und/oder behandeln von zellen |
| AU2001289791A AU2001289791A1 (en) | 2000-09-19 | 2001-08-08 | Method and device for growing and/or treating cells |
| US10/380,690 US6908767B2 (en) | 2000-09-19 | 2001-08-08 | Method and device for growing and/or treating cells |
| DK01969578T DK1319062T3 (da) | 2000-09-19 | 2001-08-08 | Fremgangsmåde og indretning til dyrkning og/eller behandling af celler |
| EP01969578A EP1319062B1 (de) | 2000-09-19 | 2001-08-08 | Verfahren und vorrichtung zum züchten und/oder behandeln von zellen |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10046175.1 | 2000-09-19 | ||
| DE10046175A DE10046175A1 (de) | 2000-09-19 | 2000-09-19 | Verfahren und Vorrichtung zum Züchten und/oder Behandeln von Zellen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2002024861A2 WO2002024861A2 (de) | 2002-03-28 |
| WO2002024861A3 true WO2002024861A3 (de) | 2002-12-05 |
Family
ID=7656675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2001/009159 Ceased WO2002024861A2 (de) | 2000-09-19 | 2001-08-08 | Verfahren und vorrichtung zum züchten und/oder behandeln von zellen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6908767B2 (de) |
| EP (1) | EP1319062B1 (de) |
| AT (1) | ATE389008T1 (de) |
| AU (1) | AU2001289791A1 (de) |
| DE (2) | DE10046175A1 (de) |
| DK (1) | DK1319062T3 (de) |
| ES (1) | ES2302746T3 (de) |
| PT (1) | PT1319062E (de) |
| WO (1) | WO2002024861A2 (de) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10118905A1 (de) * | 2001-04-18 | 2002-10-24 | Evotec Ag | Verfahren und Vorrichtung zum Kultivieren und/oder Verteilen von Partikeln |
| US6626051B2 (en) | 2001-08-14 | 2003-09-30 | Investigen Biotechnologies, Inc. | Lid for sample holder |
| WO2003026797A2 (en) * | 2001-09-21 | 2003-04-03 | Solvias Ag | Sealing system with flow channels |
| DE10201259A1 (de) * | 2002-01-15 | 2003-08-28 | Augustinus Bader | Vorrichtung zum Züchten oder Kultivieren von Zellen in einem dosenartigen Behälter |
| DE10221565A1 (de) * | 2002-05-15 | 2003-12-04 | Evotec Ag | Vorrichtung zum Kultivieren von Partikeln |
| DE10234742A1 (de) * | 2002-07-30 | 2004-02-19 | Bionethos Holding | Verfahren und Vorrichtung zum Züchten von Zellen |
| DE10260690B4 (de) * | 2002-12-23 | 2006-10-12 | Technische Universität München | Abdeckung für eine Vorrichtung, damit abgedeckte Vorrichtung und Verfahren zur parallelen, automatisierten Kultivierung von Zellen unter technischen Bedingungen |
| FI115060B (fi) * | 2003-04-22 | 2005-02-28 | Chip Man Technologies Oy | Analyysi- ja kasvatuslaitteisto |
| DE102004024833A1 (de) * | 2004-05-19 | 2005-12-29 | Universität Rostock | Vorrichtung zur Regelung des Füllstands von Medium in einem Kulturgefäß |
| FI117899B (fi) * | 2004-07-09 | 2007-04-13 | Chip Man Technologies Oy | Solujen kasvatusalusta ja sen käyttö |
| GB0505379D0 (en) * | 2005-03-16 | 2005-04-20 | Robio Systems Ltd | Cellular entity maturation and transportation systems |
| EP1904619A4 (de) | 2005-07-07 | 2012-05-02 | Univ California | Verfahren und vorrichtung für zellkultur-array |
| US9388374B2 (en) | 2005-07-07 | 2016-07-12 | Emd Millipore Corporation | Microfluidic cell culture systems |
| US8257964B2 (en) | 2006-01-04 | 2012-09-04 | Cell ASIC | Microwell cell-culture device and fabrication method |
| US9354156B2 (en) | 2007-02-08 | 2016-05-31 | Emd Millipore Corporation | Microfluidic particle analysis method, device and system |
| US9637715B2 (en) | 2005-07-07 | 2017-05-02 | Emd Millipore Corporation | Cell culture and invasion assay method and system |
| US7745209B2 (en) * | 2005-07-26 | 2010-06-29 | Corning Incorporated | Multilayered cell culture apparatus |
| US7981668B2 (en) * | 2006-01-18 | 2011-07-19 | Kci Licensing Inc. | System and method for applying reduced pressure to cell culture |
| DE102006030068A1 (de) | 2006-06-28 | 2008-01-03 | M2P-Labs Gmbh | Vorrichtung und Verfahren zur Zu- und Abfuhr von Fluiden in geschüttelten Mikroreaktoren Arrays |
| US7745210B2 (en) * | 2006-06-30 | 2010-06-29 | Corning Incorporated | Fluid flow diverter for cell culture vessel |
| CA2754719C (en) * | 2006-08-10 | 2013-12-31 | Allen C. Barnes | Portable biological testing device and method |
| DE102006043656B4 (de) * | 2006-09-18 | 2023-08-10 | Pieter Van Weenen & Co. Gmbh The House Of Innovation | Begasungsvorrichtung und- System |
| US7897379B2 (en) * | 2007-02-26 | 2011-03-01 | Corning Incorporated | Device and method for reducing bubble formation in cell culture |
| WO2008106515A1 (en) * | 2007-02-27 | 2008-09-04 | The Board Of Trustees Of The University Of Illinois | Insert device for multiwell plate |
| US9309491B2 (en) | 2007-05-29 | 2016-04-12 | Corning Incorporated | Cell culture apparatus for co-culture of cells |
| EP3173787B1 (de) | 2008-01-03 | 2021-06-02 | EMD Millipore Corporation | Zellkultur-array-system für automatisierte assays und verfahren zum betrieb und dessen herstellung |
| US20090234332A1 (en) * | 2008-03-17 | 2009-09-17 | The Charles Stark Draper Laboratory, Inc | Artificial microvascular device and methods for manufacturing and using the same |
| KR101131303B1 (ko) * | 2009-06-08 | 2012-03-30 | 한국과학기술원 | 세포 배양 장치 및 시스템과 이를 이용한 세포 배양 방법 |
| DE102009036695B3 (de) * | 2009-08-07 | 2011-04-07 | Hp Medizintechnik Gmbh | Einsatz für ein Well in einer Multiwellplatte und dessen Verwendung |
| DE102009039868B4 (de) * | 2009-09-03 | 2020-12-31 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anordnung zur Durchführung eines Verfahrens zur Untersuchung der Wirkung eines gasförmigen Mediums auf ein biologisches Prüfsystem unter Verwendung eines extrazellulären Metabolisierungssystems |
| US9353342B2 (en) | 2010-01-21 | 2016-05-31 | Emd Millipore Corporation | Cell culture and gradient migration assay methods and devices |
| DE102010005415B4 (de) | 2010-01-22 | 2015-07-16 | Zellwerk Gmbh | Verfahren und Vorrichtung zur dynamischen Expansion und/oder Differenzierung von suspendierten primären Zellen oder Stammzellen humanen und tierischen Ursprungs |
| US10526572B2 (en) | 2011-04-01 | 2020-01-07 | EMD Millipore Corporaticn | Cell culture and invasion assay method and system |
| SG11201402558QA (en) | 2011-12-03 | 2014-06-27 | Emd Millipore Corp | Micro-incubation systems for microfluidic cell culture and methods |
| US20150050722A1 (en) * | 2012-02-06 | 2015-02-19 | CS Laboratory Technologies LLC | Cell Culture Strain Array Systems and Methods for Using the Same |
| US10012640B2 (en) * | 2013-02-14 | 2018-07-03 | Cfd Research Corporation | Cell culture device with an array of microfluidic networks |
| US9790465B2 (en) | 2013-04-30 | 2017-10-17 | Corning Incorporated | Spheroid cell culture well article and methods thereof |
| DE102013109450B4 (de) * | 2013-08-30 | 2015-04-02 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Expositionsapparat |
| EP3114207A4 (de) * | 2014-03-03 | 2017-10-25 | Kiyatec Inc. | 3d-gewebekultur-vorrichtungen und -systeme |
| CH709970A1 (fr) * | 2014-08-08 | 2016-02-15 | Smtec Sport & Medical Technologies Sa | Procédé pour alimenter en gaz un environnement affecté à la culture cellulaire artificielle et dispositif pour la mise en œuvre de ce procédé. |
| EP3212760A1 (de) | 2014-10-29 | 2017-09-06 | Corning Incorporated | Perfusionsbioreaktorplattform |
| JP2017532971A (ja) | 2014-10-29 | 2017-11-09 | コーニング インコーポレイテッド | 細胞培養集合体を生成するためのマイクロウェル設計および製造 |
| SG11201703493SA (en) | 2014-10-29 | 2017-05-30 | Corning Inc | Cell culture insert |
| WO2016157378A1 (ja) * | 2015-03-30 | 2016-10-06 | 高砂電気工業株式会社 | 培地交換ユニット |
| GB201506445D0 (en) * | 2015-04-16 | 2015-06-03 | Insphero Ag | System for propagating cells |
| EP4446402A3 (de) * | 2015-05-08 | 2025-01-08 | Wilson Wolf Manufacturing, LLC | Verbesserte kulturverfahren und vorrichtungen zum testen |
| US20170253844A1 (en) * | 2016-03-04 | 2017-09-07 | Corning Incorporated | Bowl shaped microwell |
| KR20230019986A (ko) * | 2016-11-24 | 2023-02-09 | 알베오릭스 테크놀러지스 아게 | 세포 배양 시스템 및 방법 |
| AT519521B1 (de) * | 2016-12-30 | 2018-10-15 | Hektros S R L | Perfusionsvorrichtung |
| EP3545075A2 (de) * | 2017-01-19 | 2019-10-02 | Essen Instruments, Inc. D/B/A Essen BioScience, Inc. | Verfahren und vorrichtung für perfusion und umweltsteuerung von mikroplattenlaborutensilien |
| US10883978B2 (en) * | 2017-01-31 | 2021-01-05 | Agilent Technologies, Inc. | Method and device for calibration of biological flux |
| SG11201909419XA (en) | 2017-04-10 | 2019-11-28 | TheWell Bioscience | Hydrogel for cell culture and biomedical applications |
| US11857970B2 (en) | 2017-07-14 | 2024-01-02 | Corning Incorporated | Cell culture vessel |
| JP7245222B2 (ja) | 2017-07-14 | 2023-03-23 | コーニング インコーポレイテッド | 手動又は自動で培地を交換するための3d細胞培養容器 |
| CN111094536B (zh) | 2017-07-14 | 2024-03-29 | 康宁股份有限公司 | 用于3d培养的细胞培养容器及培养3d细胞的方法 |
| JP7197557B2 (ja) | 2017-07-14 | 2022-12-27 | コーニング インコーポレイテッド | 多孔性支持体を有する細胞培養槽 |
| WO2019114996A1 (de) * | 2017-12-15 | 2019-06-20 | Technische Universität Ilmenau | Mikrobioreaktoranordnung |
| JP7171696B2 (ja) | 2018-07-13 | 2022-11-15 | コーニング インコーポレイテッド | 相互接続されたウェルを有するマイクロプレートを備えた流体デバイス |
| JP7171695B2 (ja) | 2018-07-13 | 2022-11-15 | コーニング インコーポレイテッド | 液体培地送達面を含む側壁を有するマイクロキャビティ皿 |
| PL3649229T3 (pl) | 2018-07-13 | 2021-12-06 | Corning Incorporated | Naczynia do hodowli komórkowych ze stabilizującymi urządzeniami |
| EP3843898A1 (de) | 2018-08-31 | 2021-07-07 | Lucid Scientific, Inc. | Messung eines dynamischen systems |
| WO2020182646A1 (de) * | 2019-03-08 | 2020-09-17 | Leica Microsystems Cms Gmbh | Verarbeitungssystem und verarbeitungsverfahren für in form dreidimensionaler verbünde kultivierte zellen und computerprogramm |
| US12546733B2 (en) * | 2019-05-08 | 2026-02-10 | Shimadzu Corporation | Cell evaluation device |
| DE102019124678B3 (de) * | 2019-09-13 | 2020-12-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vorrichtung zur quantitativen und/oder qualitativen Analyse von Substanzen in einem Medium |
| CN112625902B (zh) * | 2020-12-03 | 2024-02-13 | 广州迈普再生医学科技股份有限公司 | 一种生物反应器及具有其的生物反应系统 |
| WO2022265970A1 (en) * | 2021-06-15 | 2022-12-22 | Lucid Scientific, Inc. | Lid with variable interlayer gap |
| WO2024112917A1 (en) * | 2022-11-22 | 2024-05-30 | The University Of North Carolina At Chapel Hill | Laminar flow incorporated scaffold-based 3d cell cultures |
| CN121358843A (zh) * | 2023-02-02 | 2026-01-16 | 夏春光 | 用于孔内高通量3d细胞培养的装置及方法 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2269391A (en) * | 1992-07-16 | 1994-02-09 | Roehm Gmbh | Apparatus for cultivating microorganisms |
| US5462874A (en) * | 1993-06-23 | 1995-10-31 | Wolf; Martin L. | Dialyzed multiple well tissue culture plate |
| DE29519602U1 (de) * | 1995-12-11 | 1996-04-18 | Reimann, Hans-Jürgen, Prof. Dr. Dr., 82067 Ebenhausen | Mobile Inkubationsvorrichtung |
| WO1997033179A1 (de) * | 1996-03-05 | 1997-09-12 | Novartis Ag | Testsystem für chemische stoffe oder stoffgemische |
| US5707869A (en) * | 1994-06-28 | 1998-01-13 | Wolf; Martin L. | Compartmentalized multiple well tissue culture plate |
| WO2002011880A2 (de) * | 2000-08-09 | 2002-02-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Mikroreaktoranordnung zur festphasengestützten synthese sowie mikroreaktorsystem mit einzelnen mikroreaktoranordnungen |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0929809B1 (de) * | 1995-12-08 | 2000-03-22 | Martin Raithel | Verfahren und vorrichtung zur in-vitro diagnose allergischer erkrankungen |
| DE19719751A1 (de) | 1997-05-10 | 1998-11-12 | Augustinus Dr Med Bader | Vorrichtung zum Züchten und/oder Behandeln von Zellen |
| DE19935643A1 (de) | 1999-07-29 | 2001-02-01 | Augustinus Bader | Vorrichtung zum Züchten und/oder Behandeln von Zellen |
-
2000
- 2000-09-19 DE DE10046175A patent/DE10046175A1/de not_active Withdrawn
-
2001
- 2001-08-08 EP EP01969578A patent/EP1319062B1/de not_active Expired - Lifetime
- 2001-08-08 DE DE50113731T patent/DE50113731D1/de not_active Expired - Lifetime
- 2001-08-08 US US10/380,690 patent/US6908767B2/en not_active Expired - Fee Related
- 2001-08-08 ES ES01969578T patent/ES2302746T3/es not_active Expired - Lifetime
- 2001-08-08 AT AT01969578T patent/ATE389008T1/de active
- 2001-08-08 PT PT01969578T patent/PT1319062E/pt unknown
- 2001-08-08 WO PCT/EP2001/009159 patent/WO2002024861A2/de not_active Ceased
- 2001-08-08 AU AU2001289791A patent/AU2001289791A1/en not_active Abandoned
- 2001-08-08 DK DK01969578T patent/DK1319062T3/da active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2269391A (en) * | 1992-07-16 | 1994-02-09 | Roehm Gmbh | Apparatus for cultivating microorganisms |
| US5462874A (en) * | 1993-06-23 | 1995-10-31 | Wolf; Martin L. | Dialyzed multiple well tissue culture plate |
| US5707869A (en) * | 1994-06-28 | 1998-01-13 | Wolf; Martin L. | Compartmentalized multiple well tissue culture plate |
| DE29519602U1 (de) * | 1995-12-11 | 1996-04-18 | Reimann, Hans-Jürgen, Prof. Dr. Dr., 82067 Ebenhausen | Mobile Inkubationsvorrichtung |
| WO1997033179A1 (de) * | 1996-03-05 | 1997-09-12 | Novartis Ag | Testsystem für chemische stoffe oder stoffgemische |
| WO2002011880A2 (de) * | 2000-08-09 | 2002-02-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Mikroreaktoranordnung zur festphasengestützten synthese sowie mikroreaktorsystem mit einzelnen mikroreaktoranordnungen |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001289791A1 (en) | 2002-04-02 |
| US6908767B2 (en) | 2005-06-21 |
| EP1319062A2 (de) | 2003-06-18 |
| WO2002024861A2 (de) | 2002-03-28 |
| ES2302746T3 (es) | 2008-08-01 |
| DE10046175A1 (de) | 2002-03-28 |
| PT1319062E (pt) | 2008-06-19 |
| DE50113731D1 (de) | 2008-04-24 |
| US20030186217A1 (en) | 2003-10-02 |
| DK1319062T3 (da) | 2008-07-14 |
| ATE389008T1 (de) | 2008-03-15 |
| EP1319062B1 (de) | 2008-03-12 |
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