WO2002034774A3 - Bacillus thuringiensis proteins and variants thereof with pesticidal activity against coleopterans - Google Patents

Bacillus thuringiensis proteins and variants thereof with pesticidal activity against coleopterans Download PDF

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Publication number
WO2002034774A3
WO2002034774A3 PCT/US2001/045468 US0145468W WO0234774A3 WO 2002034774 A3 WO2002034774 A3 WO 2002034774A3 US 0145468 W US0145468 W US 0145468W WO 0234774 A3 WO0234774 A3 WO 0234774A3
Authority
WO
WIPO (PCT)
Prior art keywords
pesticidal activity
variants
bacillus thuringiensis
activity against
nucleic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/045468
Other languages
French (fr)
Other versions
WO2002034774A2 (en
Inventor
Andre R Abad
Nicholas B Duck
Xiang Feng
Ronald D Flannagan
Theodore W Kahn
Lynne E Sims
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Priority to MXPA03003666A priority Critical patent/MXPA03003666A/en
Priority to DE60122931T priority patent/DE60122931T2/en
Priority to AU2002228705A priority patent/AU2002228705A1/en
Priority to BR0114891-5A priority patent/BR0114891A/en
Priority to HU0302523A priority patent/HU228699B1/en
Priority to CA2426793A priority patent/CA2426793C/en
Priority to EP01988728A priority patent/EP1356054B1/en
Publication of WO2002034774A2 publication Critical patent/WO2002034774A2/en
Anticipated expiration legal-status Critical
Publication of WO2002034774A3 publication Critical patent/WO2002034774A3/en
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Insects & Arthropods (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding δ-endotoxins having pesticidal activity against pests of the order Coleoptera. The invention further provides mutagenized nucleic acids that have been modified to encode endotoxins having improved pesticidal activity and/or altered pest specificity. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, expression cassettes, and transformed microorganisms and plants comprising a nucleic acid of the invention. These compositions find use in methods for controlling pests, especially plant pests.
PCT/US2001/045468 2000-10-24 2001-10-24 Bacillus thuringiensis proteins and variants thereof with pesticidal activity against coleopterans Ceased WO2002034774A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
MXPA03003666A MXPA03003666A (en) 2000-10-24 2001-10-24 Genes encoding novel proteins with pesticidal activity against coleopterans.
DE60122931T DE60122931T2 (en) 2000-10-24 2001-10-24 PROTEINS OF BACILLUS THURINGIENSIS AND VARIANTS THEREOF WITH PESTICIDAL ACTIVITY AGAINST COLEOPTERAN SKULLS
AU2002228705A AU2002228705A1 (en) 2000-10-24 2001-10-24 Bacillus thuringiensis proteins and variants thereof with pesticidal activity against coleopterans
BR0114891-5A BR0114891A (en) 2000-10-24 2001-10-24 Genes encoding new proteins with pesticide activity against beetles
HU0302523A HU228699B1 (en) 2000-10-24 2001-10-24 Genes encoding novel proteins with pesticidal activity against coleopterans
CA2426793A CA2426793C (en) 2000-10-24 2001-10-24 Bacillus thuringiensis proteins and variants thereof with pesticidal activity against coleopterans
EP01988728A EP1356054B1 (en) 2000-10-24 2001-10-24 Bacillus thuringiensis proteins and vatiants thereof with pesticidal activity against coleopterans

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24283800P 2000-10-24 2000-10-24
US60/242,838 2000-10-24
US10/032,717 US7605304B2 (en) 2000-10-24 2001-10-23 Genes encoding novel bacillus thuringiensis proteins with pesticidal activity against coleopterans
US10/032,717 2001-10-23

Publications (2)

Publication Number Publication Date
WO2002034774A2 WO2002034774A2 (en) 2002-05-02
WO2002034774A3 true WO2002034774A3 (en) 2003-08-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/045468 Ceased WO2002034774A2 (en) 2000-10-24 2001-10-24 Bacillus thuringiensis proteins and variants thereof with pesticidal activity against coleopterans

Country Status (11)

Country Link
US (3) US7605304B2 (en)
EP (1) EP1356054B1 (en)
AT (1) ATE338820T1 (en)
AU (1) AU2002228705A1 (en)
BR (1) BR0114891A (en)
CA (1) CA2426793C (en)
DE (1) DE60122931T2 (en)
ES (1) ES2271098T3 (en)
HU (1) HU228699B1 (en)
MX (1) MXPA03003666A (en)
WO (1) WO2002034774A2 (en)

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CN100532555C (en) * 2004-11-16 2009-08-26 中国农业科学院植物保护研究所 High-efficiency cry8F gene for coleopteran pests, its expressed protein and its application
WO2006125065A2 (en) * 2005-05-18 2006-11-23 The Board Of Trustees Operating Michigan State University Resistance to soybean aphid in early maturing soybean germplasm
CA2611539C (en) 2005-06-08 2017-02-28 Pioneer Hi-Bred International, Inc. Insect-specific protease recognition sequences
US7329736B2 (en) * 2006-04-14 2008-02-12 Pioneer Hi-Bred International, Inc. Bacillus thuringiensis cry gene and protein
US7449552B2 (en) * 2006-04-14 2008-11-11 Pioneer Hi-Bred International, Inc. Bacillus thuringiensis cry gene and protein
US9133475B2 (en) 2008-11-26 2015-09-15 Board Of Trustees Of Michigan State University Aphid resistant soybean plants
WO2010096613A1 (en) 2009-02-19 2010-08-26 Pioneer Hi-Bred International, Inc. Blended refuge deployment via manipulation during hybrid seed production
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WO2011009182A2 (en) 2009-07-24 2011-01-27 Embrapa - Empresa Brasileira De Pesquisa Agropecuária Isolated nucleic acid molecule, genetic construct, vector, transgenic cell, method for producing a transgenic cell and plant, isolated and purified polypeptide, biodegradable pesticide composition, pest control method, method for producing transgenic strains resistant to insect pests
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US9125419B2 (en) * 2012-08-14 2015-09-08 Marrone Bio Innovations, Inc. Bacillus sp. strain with antifungal, antibacterial and growth promotion activity
US10253329B2 (en) 2013-01-04 2019-04-09 Board Of Trustees Of Michigan State University Sources of aphid resistance in soybean plants
EA028528B1 (en) 2013-03-13 2017-11-30 Пайонир Хай-Бред Интернэшнл, Инк. Glyphosate application for weed control in brassica
BR112015023285B1 (en) 2013-03-14 2022-03-03 Pioneer Hi-Bred International, Inc. Expression cassette, bacterial host cell and method for controlling a coleopteran-like plant pest
CA2901316A1 (en) 2013-03-15 2014-09-25 Pioneer Hi-Bred International, Inc. Phi-4 polypeptides and methods for their use
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MX359026B (en) 2013-08-16 2018-09-12 Pioneer Hi Bred Int Insecticidal proteins and methods for their use.
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Also Published As

Publication number Publication date
DE60122931T2 (en) 2007-06-21
US7696412B2 (en) 2010-04-13
US20090291896A1 (en) 2009-11-26
ATE338820T1 (en) 2006-09-15
HUP0302523A3 (en) 2005-11-28
US7605304B2 (en) 2009-10-20
US8188036B2 (en) 2012-05-29
BR0114891A (en) 2005-06-28
CA2426793C (en) 2012-03-20
EP1356054B1 (en) 2006-09-06
AU2002228705A1 (en) 2002-05-06
CA2426793A1 (en) 2002-05-02
HUP0302523A2 (en) 2003-10-28
MXPA03003666A (en) 2005-01-25
DE60122931D1 (en) 2006-10-19
US20030177528A1 (en) 2003-09-18
WO2002034774A2 (en) 2002-05-02
ES2271098T3 (en) 2007-04-16
EP1356054A2 (en) 2003-10-29
US20020151709A1 (en) 2002-10-17
HU228699B1 (en) 2013-05-28

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