WO2002037158A3 - Cytological imaging systems and methods - Google Patents

Cytological imaging systems and methods Download PDF

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Publication number
WO2002037158A3
WO2002037158A3 PCT/US2001/046810 US0146810W WO0237158A3 WO 2002037158 A3 WO2002037158 A3 WO 2002037158A3 US 0146810 W US0146810 W US 0146810W WO 0237158 A3 WO0237158 A3 WO 0237158A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
imaging systems
relates
cytological
cytological imaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/046810
Other languages
French (fr)
Other versions
WO2002037158A2 (en
WO2002037158A8 (en
Inventor
Roy Ostgaard
Kevin Predmore
Mark Wilson
Howard Greene
Theodore S Geiselman
David Zahniser
Steven Meuse
William Knox
Scott Danhof
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytyc Corp
Original Assignee
Cytyc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytyc Corp filed Critical Cytyc Corp
Priority to JP2002539859A priority Critical patent/JP2004517349A/en
Priority to AU2002228837A priority patent/AU2002228837B2/en
Priority to AU2883702A priority patent/AU2883702A/en
Priority to EP01989956A priority patent/EP1332396A2/en
Publication of WO2002037158A2 publication Critical patent/WO2002037158A2/en
Publication of WO2002037158A3 publication Critical patent/WO2002037158A3/en
Anticipated expiration legal-status Critical
Publication of WO2002037158A8 publication Critical patent/WO2002037158A8/en
Priority to AU2007219377A priority patent/AU2007219377B2/en
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • G02B21/241Devices for focusing
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • G02B21/241Devices for focusing
    • G02B21/244Devices for focusing using image analysis techniques

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Multimedia (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Focus Adjustment (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to the analysis of specimens. Specifically, the invention relates to methods and apparatus for reviewing specimen slides, including apparatus for holding the slides. The invention also relates to an automatic focusing method for an imaging system and methods for accommodating vibration in the imaging system. In particular, the methods and apparatus may be applied to the automated analysis of cytological specimen slides.
PCT/US2001/046810 2000-11-03 2001-11-05 Cytological imaging systems and methods Ceased WO2002037158A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2002539859A JP2004517349A (en) 2000-11-03 2001-11-05 Systems and methods for imaging cells
AU2002228837A AU2002228837B2 (en) 2000-11-03 2001-11-05 Cytological imaging systems and methods
AU2883702A AU2883702A (en) 2000-11-03 2001-11-05 Cytological imaging systems and methods
EP01989956A EP1332396A2 (en) 2000-11-03 2001-11-05 Cytological imaging systems and methods
AU2007219377A AU2007219377B2 (en) 2000-11-03 2007-09-28 Cytological imaging systems and methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24597100P 2000-11-03 2000-11-03
US60/245,971 2000-11-03

Publications (3)

Publication Number Publication Date
WO2002037158A2 WO2002037158A2 (en) 2002-05-10
WO2002037158A3 true WO2002037158A3 (en) 2003-01-30
WO2002037158A8 WO2002037158A8 (en) 2004-04-29

Family

ID=22928837

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046810 Ceased WO2002037158A2 (en) 2000-11-03 2001-11-05 Cytological imaging systems and methods

Country Status (4)

Country Link
EP (2) EP1332396A2 (en)
JP (2) JP2004517349A (en)
AU (3) AU2002228837B2 (en)
WO (1) WO2002037158A2 (en)

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Publication number Priority date Publication date Assignee Title
US8350905B2 (en) 2008-01-23 2013-01-08 Olympus Corporation Microscope system, image generating method, and program for practicing the same
KR101230202B1 (en) 2005-01-21 2013-02-05 사이틱 코포레이션 Slide misload detection system

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Publication number Priority date Publication date Assignee Title
ATE539342T1 (en) * 2003-06-12 2012-01-15 Cytyc Corp SYSTEM FOR ORGANIZING SEVERAL OBJECTS OF INTEREST IN A FIELD OF INTEREST
DE10336803A1 (en) 2003-08-11 2005-03-24 Leica Microsystems Wetzlar Gmbh Method and system for device-independent determination of coordinates of a point imaged by means of a microscope
DE10355526A1 (en) * 2003-11-21 2005-06-09 Carl Zeiss Jena Gmbh Observation device with separate control unit
DE10355525A1 (en) * 2003-11-21 2005-06-16 Carl Zeiss Jena Gmbh Microscope for transmitting signals regarding components has components driven by a motor and controlled electronically and a separate control/display device
WO2005121863A1 (en) * 2004-06-11 2005-12-22 Nicholas Etienne Ross Automated diagnosis of malaria and other infections
US7199712B2 (en) * 2004-06-17 2007-04-03 Tafas Triantafyllos P System for automatically locating and manipulating positions on an object
US7508583B2 (en) 2005-09-14 2009-03-24 Cytyc Corporation Configurable cytological imaging system
JP4680052B2 (en) * 2005-12-22 2011-05-11 シスメックス株式会社 Specimen imaging apparatus and specimen analyzer including the same
WO2008007725A1 (en) * 2006-07-12 2008-01-17 Toyo Boseki Kabushiki Kaisha Analyzer and use thereof
US8878923B2 (en) * 2007-08-23 2014-11-04 General Electric Company System and method for enhanced predictive autofocusing
EP2232320B1 (en) * 2007-12-27 2012-09-26 Cytyc Corporation System for controlably scanning a cytological specimen
JP5394485B2 (en) * 2008-07-03 2014-01-22 エヌイーシー ラボラトリーズ アメリカ インク Signet ring cell detector and related methods
JP5580267B2 (en) 2011-09-08 2014-08-27 大日本スクリーン製造株式会社 Detection method
JP5615247B2 (en) 2011-09-27 2014-10-29 大日本スクリーン製造株式会社 Imaging device, detection device, and imaging method
JP5690359B2 (en) 2012-03-30 2015-03-25 株式会社Screenホールディングス Imaging apparatus and imaging method
JP5728042B2 (en) 2012-08-20 2015-06-03 株式会社Screenホールディングス Imaging device
US10088427B2 (en) 2015-03-31 2018-10-02 Samantree Medical Sa Systems and methods for in-operating-theatre imaging of fresh tissue resected during surgery for pathology assessment
RU2716746C2 (en) * 2015-07-16 2020-03-16 Конинклейке Филипс Н.В. Information transformation in digital pathology
US10495270B2 (en) * 2017-10-13 2019-12-03 The Boeing Company Light protection device for mixing multiple light sources
US10539776B2 (en) 2017-10-31 2020-01-21 Samantree Medical Sa Imaging systems with micro optical element arrays and methods of specimen imaging
US10928621B2 (en) 2017-10-31 2021-02-23 Samantree Medical Sa Sample dishes for use in microscopy and methods of their use
US11747603B2 (en) 2017-10-31 2023-09-05 Samantree Medical Sa Imaging systems with micro optical element arrays and methods of specimen imaging
JP7119085B2 (en) * 2017-11-30 2022-08-16 ライカ バイオシステムズ イメージング インコーポレイテッド Impact rescan system
KR102227604B1 (en) * 2019-05-21 2021-03-12 신한대학교 산학협력단 Apparatus for Analyzing Clinical Specimen for Medical Diagnosis
CN110724627B (en) * 2019-11-15 2022-12-09 长春长光辰英生物科学仪器有限公司 Sample bacterial colony positioning device and positioning method of single cell sorter
IT202000005050A1 (en) * 2020-03-10 2021-09-10 Elleci Tech Srl SLIDES LOADING MACHINE EQUIPPED WITH BIOLOGICAL SAMPLES
EP4657134A1 (en) * 2024-05-28 2025-12-03 Leica Microsystems CMS GmbH Control device, microscope and method for controlling a microscope

Citations (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1129742A (en) * 1914-12-14 1915-02-23 Philip A Sheaff Circle-drawing attachment for microscopes.
US3600057A (en) * 1969-04-17 1971-08-17 Raymond J Leffler Single slide microscopy apparatus
US4833382A (en) * 1986-06-06 1989-05-23 Gibbs David L Method and apparatus for use in microscope investigations
US4907158A (en) * 1987-05-29 1990-03-06 Carl-Zeiss-Stiftung Method for performing work on cells of a cell culture and apparatus therefor
WO1992004651A1 (en) * 1990-09-12 1992-03-19 Medical Research Council Microscope slide clip
JPH06324269A (en) * 1993-05-14 1994-11-25 Canon Inc Attachment for pretreatment of microscope sample and method for producing fracture surface using the same
US5469210A (en) * 1991-03-01 1995-11-21 Canon Kabushiki Kaisha Image pickup apparatus with control for output of non-vibrating images
JPH07333517A (en) * 1994-06-07 1995-12-22 Sumitomo Electric Ind Ltd Microscope system with stage coordinate recording mechanism
JPH0829693A (en) * 1994-07-13 1996-02-02 Nikon Corp Microscope equipment
US5574594A (en) * 1993-11-05 1996-11-12 Nikon Inc. Automated microscope slide marking device
JPH0973033A (en) * 1995-09-06 1997-03-18 Olympus Optical Co Ltd Marking device
US5638459A (en) * 1994-09-20 1997-06-10 Neopath, Inc. Method and apparatus for detecting a microscope slide coverslip
US5659421A (en) * 1995-07-05 1997-08-19 Neuromedical Systems, Inc. Slide positioning and holding device
US5731896A (en) * 1992-12-24 1998-03-24 Carl-Zeiss-Stiftung Microscope
EP0849765A2 (en) * 1996-12-19 1998-06-24 Schlumberger Technologies, Inc. Charged particle beam system with optical microscope
DE19718799A1 (en) * 1997-05-03 1998-11-05 Peter Heiland Imaging and / or scanning device in a raster mode with a device for compensating for image degradation caused by environmental influences
US5963368A (en) * 1995-09-15 1999-10-05 Accumed International, Inc. Specimen management system
US6049421A (en) * 1995-07-19 2000-04-11 Morphometrix Technologies Inc. Automated scanning of microscope slides
WO2000058690A1 (en) * 1999-03-31 2000-10-05 Sapporo Breweries Ltd. Coordinate transforming method in position setting means of observation device and observation device equipped with coordinate transforming means

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4262426A (en) * 1978-05-16 1981-04-21 Olympus Optical Company, Ltd. Marker assembly for use with a microscope
JPS61112114A (en) * 1984-11-06 1986-05-30 Mitsubishi Rayon Co Ltd Automatic focus adjustment method
US4741043B1 (en) * 1985-11-04 1994-08-09 Cell Analysis Systems Inc Method of and apparatus for image analyses of biological specimens
US4807979A (en) * 1986-01-24 1989-02-28 Geno Saccomanno Microscope slide marking device
US4690521A (en) * 1986-01-24 1987-09-01 Geno Saccomanno Microscope slide marking device and method
JPH0774856B2 (en) * 1986-10-16 1995-08-09 オリンパス光学工業株式会社 Automatic focus adjustment method
DE3828381C2 (en) * 1988-08-20 1997-09-11 Zeiss Carl Fa Method and device for automatically focusing an optical system
ES2015727A6 (en) * 1989-07-14 1990-09-01 Lopez Hervas Pedro Method of using a microscopic preparations marker
AU6870391A (en) * 1989-10-23 1991-05-31 Neuromedical Systems, Inc. Automated cytological specimen classification system and method
JPH06337357A (en) * 1993-05-31 1994-12-06 Nireco Corp Automatic focusing device for microscope
JP2000182555A (en) * 1998-12-15 2000-06-30 Shimadzu Corp Automatic focusing device

Patent Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1129742A (en) * 1914-12-14 1915-02-23 Philip A Sheaff Circle-drawing attachment for microscopes.
US3600057A (en) * 1969-04-17 1971-08-17 Raymond J Leffler Single slide microscopy apparatus
US4833382A (en) * 1986-06-06 1989-05-23 Gibbs David L Method and apparatus for use in microscope investigations
US4907158A (en) * 1987-05-29 1990-03-06 Carl-Zeiss-Stiftung Method for performing work on cells of a cell culture and apparatus therefor
WO1992004651A1 (en) * 1990-09-12 1992-03-19 Medical Research Council Microscope slide clip
US5469210A (en) * 1991-03-01 1995-11-21 Canon Kabushiki Kaisha Image pickup apparatus with control for output of non-vibrating images
US5731896A (en) * 1992-12-24 1998-03-24 Carl-Zeiss-Stiftung Microscope
JPH06324269A (en) * 1993-05-14 1994-11-25 Canon Inc Attachment for pretreatment of microscope sample and method for producing fracture surface using the same
US5574594A (en) * 1993-11-05 1996-11-12 Nikon Inc. Automated microscope slide marking device
JPH07333517A (en) * 1994-06-07 1995-12-22 Sumitomo Electric Ind Ltd Microscope system with stage coordinate recording mechanism
JPH0829693A (en) * 1994-07-13 1996-02-02 Nikon Corp Microscope equipment
US5638459A (en) * 1994-09-20 1997-06-10 Neopath, Inc. Method and apparatus for detecting a microscope slide coverslip
US5659421A (en) * 1995-07-05 1997-08-19 Neuromedical Systems, Inc. Slide positioning and holding device
US6049421A (en) * 1995-07-19 2000-04-11 Morphometrix Technologies Inc. Automated scanning of microscope slides
JPH0973033A (en) * 1995-09-06 1997-03-18 Olympus Optical Co Ltd Marking device
US5963368A (en) * 1995-09-15 1999-10-05 Accumed International, Inc. Specimen management system
EP0849765A2 (en) * 1996-12-19 1998-06-24 Schlumberger Technologies, Inc. Charged particle beam system with optical microscope
DE19718799A1 (en) * 1997-05-03 1998-11-05 Peter Heiland Imaging and / or scanning device in a raster mode with a device for compensating for image degradation caused by environmental influences
WO2000058690A1 (en) * 1999-03-31 2000-10-05 Sapporo Breweries Ltd. Coordinate transforming method in position setting means of observation device and observation device equipped with coordinate transforming means
EP1085292A1 (en) * 1999-03-31 2001-03-21 Sapporo Breweries Ltd. Coordinate transforming method in position setting means of observation device and observation device equipped with coordinate transforming means

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 1995, no. 02 31 March 1995 (1995-03-31) *
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 04 30 April 1996 (1996-04-30) *
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 06 28 June 1996 (1996-06-28) *
PATENT ABSTRACTS OF JAPAN vol. 1997, no. 07 31 July 1997 (1997-07-31) *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101230202B1 (en) 2005-01-21 2013-02-05 사이틱 코포레이션 Slide misload detection system
US8350905B2 (en) 2008-01-23 2013-01-08 Olympus Corporation Microscope system, image generating method, and program for practicing the same

Also Published As

Publication number Publication date
WO2002037158A2 (en) 2002-05-10
AU2007219377A1 (en) 2007-10-18
JP2004517349A (en) 2004-06-10
AU2007219377A2 (en) 2007-10-18
JP2008112190A (en) 2008-05-15
AU2007219377B2 (en) 2010-11-25
AU2002228837B2 (en) 2007-06-28
AU2883702A (en) 2002-05-15
EP2299307A2 (en) 2011-03-23
EP1332396A2 (en) 2003-08-06
WO2002037158A8 (en) 2004-04-29
EP2299307A3 (en) 2011-05-04

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