WO2002053554A3 - Tetraetherlipidderivate und tetraetherlipidderivate enthaltende liposomen und lipidagglomerate sowie deren verwendung - Google Patents

Tetraetherlipidderivate und tetraetherlipidderivate enthaltende liposomen und lipidagglomerate sowie deren verwendung Download PDF

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Publication number
WO2002053554A3
WO2002053554A3 PCT/EP2001/015356 EP0115356W WO02053554A3 WO 2002053554 A3 WO2002053554 A3 WO 2002053554A3 EP 0115356 W EP0115356 W EP 0115356W WO 02053554 A3 WO02053554 A3 WO 02053554A3
Authority
WO
WIPO (PCT)
Prior art keywords
lipid
tetraether
derivatives
agglomerates
lipid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/015356
Other languages
English (en)
French (fr)
Other versions
WO2002053554A2 (de
Inventor
Christine Kuehl
Bernhard Tewes
Martin Hagen
Felix Gropp
Ralf Littger
Uwe Marx
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bernina Biosystems GmbH
Original Assignee
Bernina Biosystems GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bernina Biosystems GmbH filed Critical Bernina Biosystems GmbH
Priority to EP01985932A priority Critical patent/EP1347964A2/de
Publication of WO2002053554A2 publication Critical patent/WO2002053554A2/de
Publication of WO2002053554A3 publication Critical patent/WO2002053554A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D323/00—Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Die Erfindung betrifft neue Tetraeterlipidderivate, die zur Herstellung von einfach und verlälich anwendbaren Liposomen und Lipidagglomeraten mit verbesserter Stabilität verwendet werden können. Die Erfindung betrifft ebenfalls Liposomen und Lipidagglomerate mit einer höheren Lebensdauer in vivo.
PCT/EP2001/015356 2000-12-28 2001-12-28 Tetraetherlipidderivate und tetraetherlipidderivate enthaltende liposomen und lipidagglomerate sowie deren verwendung Ceased WO2002053554A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP01985932A EP1347964A2 (de) 2000-12-28 2001-12-28 Tetraetherlipidderivate und tetraetherlipidderivate enthaltende liposomen und lipidagglomerate sowie deren verwendung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10065561.0 2000-12-28
DE2000165561 DE10065561A1 (de) 2000-12-28 2000-12-28 Tetraetherlipidderivate und Tetraetherlipidderivate enthaltende Liposomen und Lipidagglomerate sowie deren Verwendung

Publications (2)

Publication Number Publication Date
WO2002053554A2 WO2002053554A2 (de) 2002-07-11
WO2002053554A3 true WO2002053554A3 (de) 2002-09-19

Family

ID=7669335

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/015356 Ceased WO2002053554A2 (de) 2000-12-28 2001-12-28 Tetraetherlipidderivate und tetraetherlipidderivate enthaltende liposomen und lipidagglomerate sowie deren verwendung

Country Status (3)

Country Link
EP (1) EP1347964A2 (de)
DE (1) DE10065561A1 (de)
WO (1) WO2002053554A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003064360A1 (de) * 2002-02-01 2003-08-07 Bernina Biosystems Gmbh Synthetische tetraether und synthesestrategien dafür
DE10228857B4 (de) * 2002-06-26 2006-11-16 Surface & Interface Technologies Gmbh Rosenhof Tetraetherlipide mit kleinen Kopfgruppen, deren Herstellung und Verwendung
DE10249401A1 (de) * 2002-10-23 2004-05-13 Bernina Biosystems Gmbh Liposomen formende Zusammensetzung
DE102004033667A1 (de) * 2004-07-01 2006-02-02 Institut für Bioprozess- und Analysenmesstechnik e.V. Kompositmaterialien mit Tetraetherlipiden und deren Herstellung
DE102012216378B4 (de) * 2012-09-14 2014-05-15 Institut für Bioprozess- und Analysenmesstechnik e.V. Immobilisierungsmatrix mit Tetraetherlipidschicht, Verfahren zu deren Herstellung und Biosensorchip umfassend diese Immobilisierungsmatrix
EP2711369A1 (de) 2012-09-20 2014-03-26 Bernina Plus GmbH Liposome mit Tetraetherlipidderivaten
IL326647A (en) 2023-09-01 2026-04-01 Novoarc Gmbh Lipid nanoparticles with a nucleic acid charge and an ionizable lipid
CN119909014A (zh) * 2024-12-16 2025-05-02 南方科技大学 一种脂质体及其制备方法、应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993008202A1 (en) * 1991-10-23 1993-04-29 National Research Council Of Canada Formation of stable liposomes from lipid extracts of archaeobacteria (archaea)
US5391726A (en) * 1992-04-30 1995-02-21 The Dow Chemical Company Preparation of giant ring compounds
WO1997031927A1 (de) * 1996-02-29 1997-09-04 Freisleben H J Tetraetherlipide und diese enthaltende liposomen sowie deren verwendung
WO1999010337A1 (de) * 1997-08-22 1999-03-04 Bernina Biosystems Gmbh Tetraetherlipidderivate und tetraetherlipidderivate enthaltende liposomen und lipidagglomerate sowie deren verwendung

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993008202A1 (en) * 1991-10-23 1993-04-29 National Research Council Of Canada Formation of stable liposomes from lipid extracts of archaeobacteria (archaea)
US5391726A (en) * 1992-04-30 1995-02-21 The Dow Chemical Company Preparation of giant ring compounds
WO1997031927A1 (de) * 1996-02-29 1997-09-04 Freisleben H J Tetraetherlipide und diese enthaltende liposomen sowie deren verwendung
WO1999010337A1 (de) * 1997-08-22 1999-03-04 Bernina Biosystems Gmbh Tetraetherlipidderivate und tetraetherlipidderivate enthaltende liposomen und lipidagglomerate sowie deren verwendung

Also Published As

Publication number Publication date
WO2002053554A2 (de) 2002-07-11
EP1347964A2 (de) 2003-10-01
DE10065561A1 (de) 2002-07-11

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