WO2002058667A3 - Improved process for the production of sustained release drug delivery devices - Google Patents

Improved process for the production of sustained release drug delivery devices Download PDF

Info

Publication number
WO2002058667A3
WO2002058667A3 PCT/US2002/002119 US0202119W WO02058667A3 WO 2002058667 A3 WO2002058667 A3 WO 2002058667A3 US 0202119 W US0202119 W US 0202119W WO 02058667 A3 WO02058667 A3 WO 02058667A3
Authority
WO
WIPO (PCT)
Prior art keywords
coating layer
sustained release
suture tab
release drug
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/002119
Other languages
French (fr)
Other versions
WO2002058667A2 (en
Inventor
Michael J Brubaker
Pavlos Papadopoulos
Ramesh Krishnamoorthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Bausch and Lomb Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch and Lomb Inc filed Critical Bausch and Lomb Inc
Priority to JP2002559001A priority Critical patent/JP2004520900A/en
Priority to EP02703234A priority patent/EP1365738A2/en
Priority to CA002433528A priority patent/CA2433528A1/en
Publication of WO2002058667A2 publication Critical patent/WO2002058667A2/en
Publication of WO2002058667A3 publication Critical patent/WO2002058667A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Disclosed is an improved sustained release drug delivers device and method of producing such device. The device comprises a drug core in an impermeable cup or impermeable coating layer that is adhered to an uncured suture tab and covered with a permeable polmer coating layer that is similar to the makeup of the suture tab. The permeable polmer coating layer that covers the device, covering the impermeable coating layer and at least a portion of the drug core, is cured (after drying) along witht he uncured suture tab. The 'cocuring' or one step curing process forms a very strong bond between the outer coating layer to the suture tab preventing leaks.
PCT/US2002/002119 2001-01-26 2002-01-23 Improved process for the production of sustained release drug delivery devices Ceased WO2002058667A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2002559001A JP2004520900A (en) 2001-01-26 2002-01-23 Improved manufacturing method of sustained release drug delivery device
EP02703234A EP1365738A2 (en) 2001-01-26 2002-01-23 Improved process for the production of sustained release drug delivery devices
CA002433528A CA2433528A1 (en) 2001-01-26 2002-01-23 Improved process for the production of sustained release drug delivery devices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26444101P 2001-01-26 2001-01-26
US60/264,441 2001-01-26

Publications (2)

Publication Number Publication Date
WO2002058667A2 WO2002058667A2 (en) 2002-08-01
WO2002058667A3 true WO2002058667A3 (en) 2003-03-13

Family

ID=23006089

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/002119 Ceased WO2002058667A2 (en) 2001-01-26 2002-01-23 Improved process for the production of sustained release drug delivery devices

Country Status (5)

Country Link
US (2) US6991808B2 (en)
EP (1) EP1365738A2 (en)
JP (1) JP2004520900A (en)
CA (1) CA2433528A1 (en)
WO (1) WO2002058667A2 (en)

Cited By (2)

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US9463114B2 (en) 2004-04-15 2016-10-11 Mati Therapeutics Inc. Punctal plug with active agent
US10610407B2 (en) 2004-07-02 2020-04-07 Mati Therapeutics Inc. Treatment medium delivery device and methods for delivery of such treatment mediums to the eye using such delivery device

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US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
JP4677538B2 (en) 2001-06-12 2011-04-27 ジョンズ ホプキンズ ユニヴァーシティ スクール オヴ メディシン Reservoir device for intraocular drug delivery
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US20060034929A1 (en) * 2001-12-27 2006-02-16 Brubaker Michael J Sustained release drug delivery devices with prefabricated permeable plugs
CA2689424A1 (en) * 2002-09-29 2004-04-08 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
US7037521B2 (en) * 2003-03-28 2006-05-02 Bausch & Lomb Incorporated Using a laser for cutting a hole in a capsule for controlled drug delivery
US20050261668A1 (en) * 2003-03-28 2005-11-24 Bausch & Lomb Incorporated Drug delivery device
US20050054586A1 (en) * 2003-06-30 2005-03-10 Bartels Stephen P. Treatment of ophthalmic disorders
US20040265356A1 (en) * 2003-06-30 2004-12-30 Bausch & Lomb Incorporated Drug delivery device
US7211272B2 (en) * 2003-12-22 2007-05-01 Bausch & Lomb Incorporated Drug delivery device
US20050136095A1 (en) * 2003-12-22 2005-06-23 Brian Levy Drug delivery device with suture ring
US20050137538A1 (en) 2003-12-22 2005-06-23 Bausch & Lomb Incorporated Drug delivery device
US20050158365A1 (en) 2003-12-22 2005-07-21 David Watson Drug delivery device with mechanical locking mechanism
US20060018949A1 (en) * 2004-04-07 2006-01-26 Bausch & Lomb Incorporated Injectable biodegradable drug delivery system
WO2005120578A2 (en) * 2004-06-07 2005-12-22 California Institute Of Technology Biodegradable drug-polymer delivery system
WO2006004795A2 (en) 2004-06-25 2006-01-12 The Johns Hopkins University Angiogenesis inhibitors
US20060068012A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly (vinyl alcohol) drug delivery devices with humidity control
US20060067978A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly(vinyl alcohol) drug delivery devices
US20060067979A1 (en) * 2004-09-30 2006-03-30 Bausch & Lomb Incorporated Ophthalmic drug release device for multiple drug release
US20060067980A1 (en) * 2004-09-30 2006-03-30 Bausch & Lomb Incorporated Capsule for encasing tablets for surgical insertion into the human body
US20060078592A1 (en) * 2004-10-12 2006-04-13 Bausch & Lomb Incorporated Drug delivery systems
US20070276481A1 (en) * 2004-12-08 2007-11-29 Renner Steven B Drug delivery device
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US20060135918A1 (en) * 2004-12-22 2006-06-22 Bausch & Lomb Incorporated Reusable drug delivery device
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US20060134175A1 (en) * 2004-12-22 2006-06-22 Stephen Bartels Drug eluting pharmaceutical delivery system for treatment of ocular disease and method of use
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US9011361B2 (en) 2007-09-07 2015-04-21 Mati Therapeutics Inc. Lacrimal implant detection
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EP2207529B1 (en) * 2007-09-07 2014-12-31 Mati Therapeutics Inc. Drug cores for sustained release of therapeutic agents
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US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
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US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
AU2010256558B2 (en) * 2009-06-03 2013-10-03 Forsight Labs, Llc Anterior segment drug delivery
US10166142B2 (en) 2010-01-29 2019-01-01 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
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CN103209664A (en) 2010-08-05 2013-07-17 弗赛特影像4股份有限公司 implantable therapeutic device
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AU2011329656B2 (en) 2010-11-19 2017-01-05 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
US9668915B2 (en) 2010-11-24 2017-06-06 Dose Medical Corporation Drug eluting ocular implant
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
EP2726016B1 (en) 2011-06-28 2023-07-19 ForSight Vision4, Inc. An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye
US9974685B2 (en) 2011-08-29 2018-05-22 Mati Therapeutics Drug delivery system and methods of treating open angle glaucoma and ocular hypertension
ES2727203T3 (en) 2011-08-29 2019-10-14 Mati Therapeutics Inc Administration for sustained release of active agents to treat glaucoma and ocular hypertension
US9102105B2 (en) * 2011-09-13 2015-08-11 Vista Scientific Llc Method for forming an ocular drug delivery device
RU2740680C2 (en) 2011-09-14 2021-01-19 Форсайт Вижн5, Инк. Eye inserter device and methods
SI2755600T1 (en) 2011-09-16 2021-08-31 Forsight Vision4, Inc. Fluid exchange device
US10010448B2 (en) 2012-02-03 2018-07-03 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
EP2911623B1 (en) 2012-10-26 2019-08-14 Forsight Vision5, Inc. Ophthalmic system for sustained release of drug to eye
AU2014236455B2 (en) 2013-03-14 2018-07-12 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
AU2014241163B2 (en) 2013-03-28 2018-09-27 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
US20150342875A1 (en) 2014-05-29 2015-12-03 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
RU2695563C2 (en) 2014-07-15 2019-07-24 Форсайт Вижн4, Инк. Method and device for eye implant delivery
TW201618783A (en) 2014-08-07 2016-06-01 艾森塔製藥公司 Method for treating cancer, immune and autoimmune diseases and inflammatory diseases based on Bruton's tyrosine kinase (BTK) occupancy and BTK resynthesis rate
MY182793A (en) 2014-08-08 2021-02-05 Forsight Vision4 Inc Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
US10507101B2 (en) 2014-10-13 2019-12-17 W. L. Gore & Associates, Inc. Valved conduit
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US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
WO2017053885A1 (en) 2015-09-25 2017-03-30 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
KR20180084104A (en) 2015-11-20 2018-07-24 포사이트 비젼4, 인크. Porous structures for extended release drug delivery devices
BR112018070383A2 (en) 2016-04-05 2019-02-05 Forsight Vision4 Inc implantable ocular drug delivery devices
US11318043B2 (en) 2016-04-20 2022-05-03 Dose Medical Corporation Bioresorbable ocular drug delivery device
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CN115607358A (en) 2017-11-21 2023-01-17 弗赛特影像4股份有限公司 Fluid exchange device for expandable port delivery system and method of use
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Citations (3)

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US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5773019A (en) * 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
US5902598A (en) * 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices

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WO2002056863A2 (en) * 2000-12-29 2002-07-25 Bausch & Lomb Incorporated Sustained release drug delivery devices
US6964781B2 (en) * 2001-01-03 2005-11-15 Bausch & Lomb Incorporated Sustained release drug delivery devices with prefabricated permeable plugs
WO2002058667A2 (en) * 2001-01-26 2002-08-01 Bausch & Lomb Incorporated Improved process for the production of sustained release drug delivery devices
US6713081B2 (en) * 2001-03-15 2004-03-30 The United States Of America As Represented By The Department Of Health And Human Services Ocular therapeutic agent delivery devices and methods for making and using such devices

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5773019A (en) * 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
US5902598A (en) * 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9463114B2 (en) 2004-04-15 2016-10-11 Mati Therapeutics Inc. Punctal plug with active agent
US10610407B2 (en) 2004-07-02 2020-04-07 Mati Therapeutics Inc. Treatment medium delivery device and methods for delivery of such treatment mediums to the eye using such delivery device

Also Published As

Publication number Publication date
CA2433528A1 (en) 2002-08-01
WO2002058667A2 (en) 2002-08-01
US20020110635A1 (en) 2002-08-15
US20060062826A1 (en) 2006-03-23
US6991808B2 (en) 2006-01-31
JP2004520900A (en) 2004-07-15
EP1365738A2 (en) 2003-12-03

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