WO2002072020A3 - Novel anti-adhesive compounds and uses thereof - Google Patents

Novel anti-adhesive compounds and uses thereof Download PDF

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Publication number
WO2002072020A3
WO2002072020A3 PCT/US2002/007426 US0207426W WO02072020A3 WO 2002072020 A3 WO2002072020 A3 WO 2002072020A3 US 0207426 W US0207426 W US 0207426W WO 02072020 A3 WO02072020 A3 WO 02072020A3
Authority
WO
WIPO (PCT)
Prior art keywords
compounds
novel anti
adhesive compounds
methods
fouling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/007426
Other languages
French (fr)
Other versions
WO2002072020A2 (en
Inventor
Randall S Alberte
Robert D Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cernofina LLC
Original Assignee
Cernofina LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cernofina LLC filed Critical Cernofina LLC
Priority to AU2002255704A priority Critical patent/AU2002255704A1/en
Priority to EP02725119A priority patent/EP1385821A4/en
Priority to JP2002570980A priority patent/JP4363850B2/en
Priority to CA002441174A priority patent/CA2441174A1/en
Publication of WO2002072020A2 publication Critical patent/WO2002072020A2/en
Anticipated expiration legal-status Critical
Publication of WO2002072020A3 publication Critical patent/WO2002072020A3/en
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C305/00—Esters of sulfuric acids
    • C07C305/22—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to carbon atoms of six-membered aromatic rings
    • C07C305/24—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to carbon atoms of six-membered aromatic rings of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/14—Libraries containing macromolecular compounds and not covered by groups C40B40/06 - C40B40/12
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Polymers & Plastics (AREA)
  • Structural Engineering (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Compounds which exhibit anti-adhesive properties are described. The compounds may be monomers or polymers. Methods for treating receptor mediated diseases are provided using compounds of the invention. Further methods are provided for crop protection, medical devices and anti-fouling.
PCT/US2002/007426 2001-03-12 2002-03-12 Novel anti-adhesive compounds and uses thereof Ceased WO2002072020A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2002255704A AU2002255704A1 (en) 2001-03-12 2002-03-12 Novel anti-adhesive compounds and uses thereof
EP02725119A EP1385821A4 (en) 2001-03-12 2002-03-12 Novel anti-adhesive compounds and uses thereof
JP2002570980A JP4363850B2 (en) 2001-03-12 2002-03-12 Novel anti-adhesion compounds and their use
CA002441174A CA2441174A1 (en) 2001-03-12 2002-03-12 Novel anti-adhesive compounds and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27522301P 2001-03-12 2001-03-12
US60/275,223 2001-03-12

Publications (2)

Publication Number Publication Date
WO2002072020A2 WO2002072020A2 (en) 2002-09-19
WO2002072020A3 true WO2002072020A3 (en) 2003-11-27

Family

ID=23051374

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/007426 Ceased WO2002072020A2 (en) 2001-03-12 2002-03-12 Novel anti-adhesive compounds and uses thereof

Country Status (5)

Country Link
EP (1) EP1385821A4 (en)
JP (2) JP4363850B2 (en)
AU (1) AU2002255704A1 (en)
CA (1) CA2441174A1 (en)
WO (1) WO2002072020A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
DE10246625A1 (en) 2002-10-07 2004-04-15 Basf Ag Destruction of microorganisms in aqueous systems, involves addition of a water-soluble or -dispersible styrene sulfonic acid (co) polymer as biocide
US20100168228A1 (en) * 2006-10-13 2010-07-01 Reliance Life Sciences Pvt. Ltd. Novel chemotherapeutic agents against inflammation and cancer
CN103923243B (en) * 2014-04-11 2016-06-01 东南大学 A kind of optically-active polyacetylene infrared low-emissivity material and its preparation method
CN108367171A (en) * 2015-12-24 2018-08-03 荷兰联合利华有限公司 Composite material for biomembrane control

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3331798A (en) * 1962-01-08 1967-07-18 Dow Chemical Co Viscous aqueous blend of polystyrene sulfonate and n-vinylpyrrolidinone, and preparation thereof
US3432454A (en) * 1965-03-24 1969-03-11 Dow Chemical Co Viscous aqueous compositions comprising a polymer containing n-vinyl morpholinone and a polymer containing sulfo or carboxyl groups or their salts
US4507235A (en) * 1979-04-30 1985-03-26 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Method for preparing peptides and intermediate products
US5208316A (en) * 1990-10-01 1993-05-04 Toppan Printing Co., Ltd. Cyclodextrin polymer and cyclodextrin membrane prepared using said polymer
US5294530A (en) * 1991-05-17 1994-03-15 Fuji Photo Film Co., Ltd. Silver halide color photographic material
EP0801117A2 (en) * 1996-04-11 1997-10-15 Nippon Paint Co., Ltd. Antifouling resin composition
EP0596023B1 (en) * 1991-07-19 1998-10-14 J.C. Hempel's Skibsfarve-Fabrik A/S Paint composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4375461A (en) * 1980-07-25 1983-03-01 Johnson & Johnson Products, Inc. Sulfonated vinyl aromatic homopolymers and copolymers as dental plaque barriers
DE59712479D1 (en) * 1996-03-21 2005-12-22 Biotronik Gmbh & Co Kg Implantable stimulation electrode
IL142130A0 (en) * 1998-09-23 2002-03-10 Phycogen Inc Safe and effective biofilm inhibitory compounds and health-related uses thereof
US7132567B2 (en) * 2000-04-03 2006-11-07 Cerno Biosciences, Llc Generation of combinatorial synthetic libraries and screening for proadhesins and nonadhesins

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3331798A (en) * 1962-01-08 1967-07-18 Dow Chemical Co Viscous aqueous blend of polystyrene sulfonate and n-vinylpyrrolidinone, and preparation thereof
US3432454A (en) * 1965-03-24 1969-03-11 Dow Chemical Co Viscous aqueous compositions comprising a polymer containing n-vinyl morpholinone and a polymer containing sulfo or carboxyl groups or their salts
US4507235A (en) * 1979-04-30 1985-03-26 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Method for preparing peptides and intermediate products
US5208316A (en) * 1990-10-01 1993-05-04 Toppan Printing Co., Ltd. Cyclodextrin polymer and cyclodextrin membrane prepared using said polymer
US5294530A (en) * 1991-05-17 1994-03-15 Fuji Photo Film Co., Ltd. Silver halide color photographic material
EP0596023B1 (en) * 1991-07-19 1998-10-14 J.C. Hempel's Skibsfarve-Fabrik A/S Paint composition
EP0801117A2 (en) * 1996-04-11 1997-10-15 Nippon Paint Co., Ltd. Antifouling resin composition

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NUZILLARD J.M., TETRAHEDRON LETTERS, vol. 27, no. 26, 1986, pages 2993 - 2996, XP002963674 *
See also references of EP1385821A4 *

Also Published As

Publication number Publication date
JP2009149688A (en) 2009-07-09
EP1385821A2 (en) 2004-02-04
CA2441174A1 (en) 2002-09-19
EP1385821A4 (en) 2006-03-08
WO2002072020A2 (en) 2002-09-19
JP4363850B2 (en) 2009-11-11
AU2002255704A1 (en) 2002-09-24
JP2004533416A (en) 2004-11-04

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