WO2002080774A3 - Method for improved measurement of local physical parameters in afluid-filled cavity - Google Patents

Method for improved measurement of local physical parameters in afluid-filled cavity Download PDF

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Publication number
WO2002080774A3
WO2002080774A3 PCT/IB2002/001229 IB0201229W WO02080774A3 WO 2002080774 A3 WO2002080774 A3 WO 2002080774A3 IB 0201229 W IB0201229 W IB 0201229W WO 02080774 A3 WO02080774 A3 WO 02080774A3
Authority
WO
WIPO (PCT)
Prior art keywords
filled cavity
physical parameters
afluid
local physical
improved measurement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2002/001229
Other languages
French (fr)
Other versions
WO2002080774A2 (en
Inventor
Peter J A Frinking
Marcel Arditi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Research SA
Original Assignee
Bracco Research SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Research SA filed Critical Bracco Research SA
Priority to AU2002253454A priority Critical patent/AU2002253454A1/en
Priority to US10/474,134 priority patent/US6962071B2/en
Priority to DE60223239T priority patent/DE60223239T2/en
Priority to JP2002578814A priority patent/JP3819845B2/en
Priority to EP02722575A priority patent/EP1387637B1/en
Publication of WO2002080774A2 publication Critical patent/WO2002080774A2/en
Publication of WO2002080774A3 publication Critical patent/WO2002080774A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G01N29/036—Analysing fluids by measuring frequency or resonance of acoustic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/481—Diagnostic techniques involving the use of contrast agents, e.g. microbubbles introduced into the bloodstream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01L—MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
    • G01L11/00—Measuring steady or quasi-steady pressure of a fluid or a fluent solid material by means not provided for in group G01L7/00 or G01L9/00
    • G01L11/04—Measuring steady or quasi-steady pressure of a fluid or a fluent solid material by means not provided for in group G01L7/00 or G01L9/00 by acoustic means
    • G01L11/06—Ultrasonic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0007—Investigating dispersion of gas
    • G01N2015/0011—Investigating dispersion of gas in liquids, e.g. bubbles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/024—Mixtures
    • G01N2291/02433—Gases in liquids, e.g. bubbles, foams
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/028—Material parameters
    • G01N2291/02854—Length, thickness
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/028—Material parameters
    • G01N2291/02872—Pressure

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Acoustics & Sound (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)

Abstract

The present invention relates to remotely determining local physical parameters in a fluid-filled cavity (e.g. heart cavities, blood vessels, industrial container) by means of ultrasound waves and encapsulated or stabilised gas bubbles. A measuring method, a method of diagnostic ultrasound of the same and an apparatus for remotely determining ambient physical local parameters of a fluid-filled cavity are disclosed.
PCT/IB2002/001229 2001-04-06 2002-04-05 Method for improved measurement of local physical parameters in afluid-filled cavity Ceased WO2002080774A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2002253454A AU2002253454A1 (en) 2001-04-06 2002-04-05 Method for improved measurement of local physical parameters in afluid-filled cavity
US10/474,134 US6962071B2 (en) 2001-04-06 2002-04-05 Method for improved measurement of local physical parameters in a fluid-filled cavity
DE60223239T DE60223239T2 (en) 2001-04-06 2002-04-05 Device for measuring local physical parameters in a liquid-filled cavity
JP2002578814A JP3819845B2 (en) 2001-04-06 2002-04-05 Improved method for measuring local physical parameters in fluid filled cavities
EP02722575A EP1387637B1 (en) 2001-04-06 2002-04-05 Apparatus for measuring local physical parameters in a fluid filled cavity

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28179401P 2001-04-06 2001-04-06
US60/281,794 2001-04-06

Publications (2)

Publication Number Publication Date
WO2002080774A2 WO2002080774A2 (en) 2002-10-17
WO2002080774A3 true WO2002080774A3 (en) 2003-02-27

Family

ID=23078815

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2002/001229 Ceased WO2002080774A2 (en) 2001-04-06 2002-04-05 Method for improved measurement of local physical parameters in afluid-filled cavity

Country Status (7)

Country Link
US (1) US6962071B2 (en)
EP (1) EP1387637B1 (en)
JP (1) JP3819845B2 (en)
AT (1) ATE376803T1 (en)
AU (1) AU2002253454A1 (en)
DE (1) DE60223239T2 (en)
WO (1) WO2002080774A2 (en)

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US6962006B2 (en) * 2002-12-19 2005-11-08 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
US20050069591A1 (en) * 2003-09-30 2005-03-31 Howard Bernstein Injectable, oral, or topical sustained release pharmaceutical formulations
US20050273010A1 (en) * 2004-06-02 2005-12-08 Shi William T Method and system for ultrasound contrast-imaging
CN100536783C (en) * 2005-01-19 2009-09-09 微星科技股份有限公司 Method and system for measuring intracranial pressure
US7837626B2 (en) * 2005-08-05 2010-11-23 Siemens Medical Solutions Usa, Inc. Contrast agent manipulation with medical ultrasound imaging
EP1780651A1 (en) * 2005-10-25 2007-05-02 Bracco Imaging, S.P.A. Method and system for automatic processing and evaluation of images, particularly diagnostic images
US10130342B2 (en) 2007-12-28 2018-11-20 Bracco Suisse Sa Initialization of fitting parameters for perfusion assessment based on bolus administration
WO2010147055A1 (en) * 2009-06-18 2010-12-23 株式会社日立メディコ Ultrasonic image pickup apparatus and ultrasonic image pickup method
EP2724140A1 (en) * 2011-06-22 2014-04-30 1st DETECT CORPORATION Reduced pressure liquid sampling
DE102013006943B4 (en) * 2013-04-23 2021-03-18 Khs Gmbh Method and device for leak testing large-volume containers
JP6523326B2 (en) * 2014-04-07 2019-05-29 ブラッコ・シュイス・ソシエテ・アノニムＢｒａｃｃｏ Ｓｕｉｓｓｅ ＳＡ In-Situ Estimation of Sound Level by Non-fundamental Analysis
CN108289654B (en) 2015-12-10 2021-03-30 博莱科瑞士股份有限公司 Detection of Immobilized Contrast Agents by Dynamic Thresholding
WO2018071551A1 (en) * 2016-10-11 2018-04-19 Thomas Jefferson University Non-invasive method for pressure measurement
CN108459357B (en) * 2018-03-01 2019-07-05 中国石油大学(华东) Evaluation method for formation undercompaction and fluid expansion overpressure
US12245894B2 (en) * 2020-02-21 2025-03-11 Pi-Harvest Holding Ag System and method for non-invasive real time assessment of cardiovascular blood pressure

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WO1999047045A1 (en) * 1998-03-20 1999-09-23 Thomas Jefferson University Microbubble-based ultrasonic contrast agents for pressure measurements

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Also Published As

Publication number Publication date
EP1387637B1 (en) 2007-10-31
AU2002253454A1 (en) 2002-10-21
US20040129082A1 (en) 2004-07-08
JP3819845B2 (en) 2006-09-13
EP1387637A2 (en) 2004-02-11
ATE376803T1 (en) 2007-11-15
JP2004529697A (en) 2004-09-30
DE60223239D1 (en) 2007-12-13
US6962071B2 (en) 2005-11-08
DE60223239T2 (en) 2008-08-14
WO2002080774A2 (en) 2002-10-17

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