WO2002081518A3 - Proteins, polynucleotides encoding them and methods of using the same - Google Patents

Proteins, polynucleotides encoding them and methods of using the same Download PDF

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Publication number
WO2002081518A3
WO2002081518A3 PCT/US2002/005374 US0205374W WO02081518A3 WO 2002081518 A3 WO2002081518 A3 WO 2002081518A3 US 0205374 W US0205374 W US 0205374W WO 02081518 A3 WO02081518 A3 WO 02081518A3
Authority
WO
WIPO (PCT)
Prior art keywords
proteins
methods
same
polynucleotides encoding
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/005374
Other languages
French (fr)
Other versions
WO2002081518A2 (en
Inventor
Carol E A Pena
Richard A Shimkets
Li Li
Suresh G Shenoy
Ramesh Kekuda
Kimberly A Spytek
Corine A M Vernet
Uriel L Malyankar
Xiaojia Guo
Vladimir Y Gusev
Stacie J Casman
Ferenc L Boldog
Katarzyna Furtak
Velizar T Tchernev
Meera Patturajan
Esha A Gangolli
Muralidhara Padigaru
Xiaohong Liu
Jason C Baumgartner
Valerie L Gerlach
Steven K Spaderna
Bryan D Zerhusen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CuraGen Corp
Original Assignee
CuraGen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CuraGen Corp filed Critical CuraGen Corp
Priority to EP02739088A priority Critical patent/EP1379554A2/en
Priority to CA002440219A priority patent/CA2440219A1/en
Publication of WO2002081518A2 publication Critical patent/WO2002081518A2/en
Anticipated expiration legal-status Critical
Publication of WO2002081518A3 publication Critical patent/WO2002081518A3/en
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05BCONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B19/00Program-control systems
    • G05B19/02Program-control systems electric
    • G05B19/18Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of program data in numerical form
    • G05B19/408Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of program data in numerical form characterised by data handling or data format, e.g. reading, buffering or conversion of data
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Human Computer Interaction (AREA)
  • Manufacturing & Machinery (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Automation & Control Theory (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
PCT/US2002/005374 2001-02-21 2002-02-21 Proteins, polynucleotides encoding them and methods of using the same Ceased WO2002081518A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02739088A EP1379554A2 (en) 2001-02-21 2002-02-21 Proteins, polynucleotides encoding them and methods of using the same
CA002440219A CA2440219A1 (en) 2001-02-21 2002-02-21 Proteins, polynucleotides encoding them and methods of using the same

Applications Claiming Priority (32)

Application Number Priority Date Filing Date Title
US27022001P 2001-02-21 2001-02-21
US27052301P 2001-02-21 2001-02-21
US60/270,523 2001-02-21
US60/270,220 2001-02-21
US27081001P 2001-02-23 2001-02-23
US27079701P 2001-02-23 2001-02-23
US60/270,810 2001-02-23
US60/270,797 2001-02-23
US27429501P 2001-03-08 2001-03-08
US60/274,295 2001-03-08
US27667701P 2001-03-16 2001-03-16
US27640001P 2001-03-16 2001-03-16
US60/276,400 2001-03-16
US60/276,677 2001-03-16
US27879601P 2001-03-26 2001-03-26
US60/278,796 2001-03-26
US28152101P 2001-04-04 2001-04-04
US60/281,521 2001-04-04
US28654801P 2001-04-25 2001-04-25
US60/286,548 2001-04-25
US29176501P 2001-05-17 2001-05-17
US60/291,765 2001-05-17
US31159501P 2001-08-10 2001-08-10
US60/311,595 2001-08-10
US31198001P 2001-08-13 2001-08-13
US60/311,980 2001-08-13
US31852601P 2001-09-10 2001-09-10
US60/318,526 2001-09-10
US32271201P 2001-09-17 2001-09-17
US60/322,712 2001-09-17
US33030701P 2001-10-18 2001-10-18
US60/330,307 2001-10-18

Publications (2)

Publication Number Publication Date
WO2002081518A2 WO2002081518A2 (en) 2002-10-17
WO2002081518A3 true WO2002081518A3 (en) 2003-10-23

Family

ID=27585835

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/005374 Ceased WO2002081518A2 (en) 2001-02-21 2002-02-21 Proteins, polynucleotides encoding them and methods of using the same

Country Status (4)

Country Link
US (1) US7108972B2 (en)
EP (1) EP1379554A2 (en)
CA (1) CA2440219A1 (en)
WO (1) WO2002081518A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004113335A2 (en) * 2003-06-20 2004-12-29 Chiron Corporation Pyridino[1,2-a]pyrimidin-4-one compounds as anticancer agents
US7399469B2 (en) 2004-03-26 2008-07-15 Pdl Biopharma, Inc. Anti-LFL2 antibodies for the diagnosis, prognosis and treatment of cancer
WO2006047357A2 (en) * 2004-10-22 2006-05-04 Biogen Idec Ma Inc. Human ly6-big molecules and methods of use
GB0525380D0 (en) * 2005-12-13 2006-01-18 Ares Trading Sa SRCR-B domain containing proteins
CA2707182C (en) * 2007-11-30 2017-12-12 Siemens Healthcare Diagnostics Inc. Adiponectin receptor fragments and methods of use
US20090186370A1 (en) * 2008-01-18 2009-07-23 Ogle Matthew F Diagnostic biomarkers for vascular aneurysm
US8856003B2 (en) 2008-04-30 2014-10-07 Motorola Solutions, Inc. Method for dual channel monitoring on a radio device
WO2010123720A1 (en) 2009-04-23 2010-10-28 Siemens Healthcare Diagnostics Inc. Monomeric and dimeric forms of adiponectin receptor fragments and methods of use
US8691760B2 (en) 2009-02-02 2014-04-08 Ramot At Tel-Aviv University Peptides, pharmaceutical compositions comprising same and uses thereof
WO2012017439A2 (en) 2010-08-04 2012-02-09 Ramot At Tel-Aviv University Ltd. Methods of treating autoimmune diseases of the central nervous system (cns) and neurodegenerative diseases
WO2012157737A1 (en) * 2011-05-19 2012-11-22 東レ株式会社 Immunity inducing agent
MX343324B (en) 2011-07-06 2016-11-01 Nestec Sa Assays for detecting neutralizing autoantibodies to biologic therapy with tnf alpha.
WO2016088104A2 (en) * 2014-12-05 2016-06-09 Nestec S.A. Indirect homogeneous mobility shift assays for the detection of biologics in patient samples
US11440665B2 (en) 2018-10-23 2022-09-13 Airbus Operations Gmbh Vented leading-edge assembly and method for manufacturing a vented leading-edge assembly
WO2022226226A1 (en) * 2021-04-21 2022-10-27 Ramot At Tel-Aviv University Ltd. Ly6s and methods of identifying and using same
CN114277005B (en) * 2021-12-28 2022-07-22 江南大学 Lipoxygenase mutant with improved catalytic efficiency and thermal stability

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000065067A2 (en) * 1999-04-23 2000-11-02 University Of Washington Prostate-specific polynucleotides, polypeptides and their methods of use
WO2001090334A2 (en) * 2000-05-25 2001-11-29 Incyte Genomics, Inc. Drug metabolizing enzymes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030032057A1 (en) * 1997-08-26 2003-02-13 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
FR2795074A1 (en) 1999-05-21 2000-12-22 Inst Nat Sante Rech Med POLYPEPTIDES TRANSPORTING AMINO ACIDS, IN PARTICULAR GLUTAMATE, AND METHODS OF SCREENING INHIBITOR OR ACTIVATOR COMPOUNDS OF TRANSPORT ACTIVITY

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000065067A2 (en) * 1999-04-23 2000-11-02 University Of Washington Prostate-specific polynucleotides, polypeptides and their methods of use
WO2001090334A2 (en) * 2000-05-25 2001-11-29 Incyte Genomics, Inc. Drug metabolizing enzymes

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 June 1999 (1999-06-01), LAI C. H. ET AL.: "Homo sapiens CGI-82 protein mRNA, complete cds", XP002237374, Database accession no. AF151840 *
DATABASE EMBL [online] 31 October 2001 (2001-10-31), ISOGAI T. ET AL.: "Homo sapiens cDNA FLJ30273 fis, clone BRACE2002685, moderately similar to Homo sapiens androgen-regulated short-chain dehydrogenase/reductase 1 (ARSDR1) mRNA", XP002237373, Database accession no. AK054835 *
HAESELEER FRANCOISE ET AL: "Short-chain dehydrogenases/reductases in retina.", METHODS IN ENZYMOLOGY, vol. 316, 2000, cycle, Part B. 2000 Academic Press Inc.; Academic Press Inc. 525 B Street, Suite 1900, San Diego, CA, 92101-4495, USA; Harcourt Place, 32 Jamestown Road, London, NW1 7BY, UK, pages 372 - 383, XP001146648, ISBN: 0-12-182217-6 *
KEDISHVILI N Y ET AL: "Cloning of the human RoDH-related short chain dehydrogenase gene and analysis of its structure", CHEMICO-BIOLOGICAL INTERACTIONS 30 JAN 2001 IRELAND, vol. 130-132, 30 January 2001 (2001-01-30), pages 457 - 467, XP001146647, ISSN: 0009-2797 *
LIN BIAOYANG ET AL: "Prostate short-chain dehydrogenase reductase 1 (PSDR1): A new member of the short-chain steroid dehydrogenase/reductase family highly expressed in normal and neoplastic prostate epithelium.", CANCER RESEARCH, vol. 61, no. 4, 15 February 2001 (2001-02-15), pages 1611 - 1618, XP002237372, ISSN: 0008-5472 *
OPPERMANN UDO C T ET AL: "Forms and functions of human SDR enzymes.", CHEMICO-BIOLOGICAL INTERACTIONS, vol. 130-132, no. 1-3, 30 January 2001 (2001-01-30), pages 699 - 705, XP001097694, ISSN: 0009-2797 *
See also references of EP1379554A2 *

Also Published As

Publication number Publication date
EP1379554A2 (en) 2004-01-14
WO2002081518A2 (en) 2002-10-17
US20040002584A1 (en) 2004-01-01
CA2440219A1 (en) 2002-10-17
US7108972B2 (en) 2006-09-19

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