WO2002086505A3 - Intracellular analysis - Google Patents

Intracellular analysis Download PDF

Info

Publication number
WO2002086505A3
WO2002086505A3 PCT/GB2002/001235 GB0201235W WO02086505A3 WO 2002086505 A3 WO2002086505 A3 WO 2002086505A3 GB 0201235 W GB0201235 W GB 0201235W WO 02086505 A3 WO02086505 A3 WO 02086505A3
Authority
WO
WIPO (PCT)
Prior art keywords
intracellular analysis
intracellular
analysis
assays
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2002/001235
Other languages
French (fr)
Other versions
WO2002086505A2 (en
Inventor
Roderick Simon Patrick Benson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Manchester
Original Assignee
Victoria University of Manchester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Victoria University of Manchester filed Critical Victoria University of Manchester
Priority to EP02724411A priority Critical patent/EP1377829A2/en
Priority to AU2002255105A priority patent/AU2002255105A1/en
Priority to US10/471,607 priority patent/US20040115740A1/en
Publication of WO2002086505A2 publication Critical patent/WO2002086505A2/en
Publication of WO2002086505A3 publication Critical patent/WO2002086505A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to a method for the intracellular analysis of a target molecule, e.g. to detect the presence and/or amount thereof and to cells for use in such assays.
PCT/GB2002/001235 2001-03-31 2002-04-02 Intracellular analysis Ceased WO2002086505A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP02724411A EP1377829A2 (en) 2001-03-31 2002-04-02 Intracellular analysis
AU2002255105A AU2002255105A1 (en) 2001-03-31 2002-04-02 Intracellular analysis
US10/471,607 US20040115740A1 (en) 2001-03-31 2002-04-02 Intracellular analysis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0108165.2 2001-03-31
GBGB0108165.2A GB0108165D0 (en) 2001-03-31 2001-03-31 Intracellular analysis

Publications (2)

Publication Number Publication Date
WO2002086505A2 WO2002086505A2 (en) 2002-10-31
WO2002086505A3 true WO2002086505A3 (en) 2003-06-05

Family

ID=9912033

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/001235 Ceased WO2002086505A2 (en) 2001-03-31 2002-04-02 Intracellular analysis

Country Status (5)

Country Link
US (1) US20040115740A1 (en)
EP (1) EP1377829A2 (en)
AU (1) AU2002255105A1 (en)
GB (1) GB0108165D0 (en)
WO (1) WO2002086505A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE49435E1 (en) 2014-11-12 2023-02-28 Seagen Inc. Glycan-interacting compounds and methods of use

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20201914T1 (en) 2013-05-06 2021-01-22 Scholar Rock, Inc. Compositions and methods for growth factor modulation
CA3002097A1 (en) 2015-11-12 2017-05-18 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
WO2018094143A1 (en) 2016-11-17 2018-05-24 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
KR20240044544A (en) 2017-03-03 2024-04-04 씨젠 인크. Glycan-interacting compounds and methods of use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040477A1 (en) * 1997-03-14 1998-09-17 The Regents Of The University Of California Fluorescent protein sensors for detection of analytes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040477A1 (en) * 1997-03-14 1998-09-17 The Regents Of The University Of California Fluorescent protein sensors for detection of analytes

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
IWAMOTO TAKU ET AL: "Visualization and monitoring of CREB-CBP interaction in living cells by FRET.", NEUROSCIENCE RESEARCH SUPPLEMENT, no. 24, 2000, 23rd Annual Meeting of the Japan Neuroscience Society and the 10th Annual Meeting of the Japanese Neural Network Society;Yokohama, Japan; September 04-06, 2000, pages S31, XP001147177, ISSN: 0921-8696 *
LI HOI YEUNG ET AL: "Protein-protein interaction of FHL3 with FHL2 and visualization of their interaction by green fluorescent proteins (GFP) two-fusion fluorescence resonance energy transfer (FRET).", JOURNAL OF CELLULAR BIOCHEMISTRY, vol. 80, no. 3, 2000, pages 293 - 303, XP002237434, ISSN: 0730-2312 *
LI Y ET AL: "The Human DF3/MUC1 carcinoma-associated antigen signals nuclear localization of the catenin p120(ctn).", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. UNITED STATES 23 FEB 2001, vol. 281, no. 2, 23 February 2001 (2001-02-23), pages 440 - 443, XP002237435, ISSN: 0006-291X *
MAHAJAN NUPAM P ET AL: "Bcl-2 and Bax interactions in mitochondrial probed with green fluorescent protein and fluorescence resonance energy transfer.", NATURE BIOTECHNOLOGY, vol. 16, no. 6, June 1998 (1998-06-01), pages 547 - 552, XP000876894, ISSN: 1087-0156 *
NG ENDERS KAI ON ET AL: "Interaction of the heart-specific LIM domain protein, FHL2, with DNA-binding nuclear protein, hNP220.", JOURNAL OF CELLULAR BIOCHEMISTRY, vol. 84, no. 3, 2001, 2001, pages 556 - 566, XP001147041, ISSN: 0730-2312 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE49435E1 (en) 2014-11-12 2023-02-28 Seagen Inc. Glycan-interacting compounds and methods of use

Also Published As

Publication number Publication date
GB0108165D0 (en) 2001-05-23
AU2002255105A1 (en) 2002-11-05
WO2002086505A2 (en) 2002-10-31
EP1377829A2 (en) 2004-01-07
US20040115740A1 (en) 2004-06-17

Similar Documents

Publication Publication Date Title
WO2003045310A8 (en) Digital assay
WO2002079490A3 (en) Bio-barcodes based on oligonucleotide-modified particles
WO2005059103A3 (en) Corn plant mon88017 and compositions and methods for detection thereof
WO2004092708A3 (en) Methods for the electrochemical detection of target compounds
WO2005003394A3 (en) Bio-barcode based detection of target analytes
WO2005052542A3 (en) Method and composition useful for determining fk 506
WO2005111212A3 (en) Biological bar code
AU2002311897A1 (en) Nucleic acid detection in pooled samples
WO2006124641A3 (en) Anti-mesothelin antibodies useful for immunological assays
WO2007008276A3 (en) Turnover probes and use thereof for nucleic acid detection
AU2002231961A1 (en) Detectable compositions, methods of forming the same and detection techniques
WO2004055117A3 (en) Carboxamide-substituted dyes for analytical applications
WO2005045075A3 (en) Sample preparation methods and devices
WO2003050291A3 (en) Sensor for the use in testing biological chemical or environmental samples
WO2003038397A3 (en) Assay
WO2003081253A3 (en) Electrochemical multi-well plate
AU2002365269A1 (en) Mut-il-18 or mut-il-18r proteins, antibodies, compositions, methods and uses
WO2002100805A3 (en) Colorimetric nanocrystal sensors, methods of making, and use thereof
WO2002058533A3 (en) Process for determining target function and identifying drug leads
AU2002306748A1 (en) Anti-gpe antibodies, their uses, and analytical methods for gpe
WO2004081535A3 (en) The establishment of proteome structure profile databases and their uses
WO2005051985A3 (en) Methods for purifying pertussis toxin and peptides useful therefor
WO2003029409A3 (en) Methods for generating, selecting, and identifying compounds which bind a target molecule
WO2004020970A3 (en) α-AMYLASE ASSAY AND USES THEREOF
WO2007066129A3 (en) A method of detecting skeletal muscle damage

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 10471607

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2002724411

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2002724411

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 2002724411

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP