WO2002102848A3 - Nucleic acid and amino acid sequences of a vegf variant - Google Patents

Nucleic acid and amino acid sequences of a vegf variant Download PDF

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Publication number
WO2002102848A3
WO2002102848A3 PCT/IL2002/000491 IL0200491W WO02102848A3 WO 2002102848 A3 WO2002102848 A3 WO 2002102848A3 IL 0200491 W IL0200491 W IL 0200491W WO 02102848 A3 WO02102848 A3 WO 02102848A3
Authority
WO
WIPO (PCT)
Prior art keywords
acid sequences
sequences
amino acid
nucleic acid
vegf variant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2002/000491
Other languages
French (fr)
Other versions
WO2002102848A2 (en
Inventor
Liat Mintz
Kinneret Savitzky
Sharon Engel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Compugen Ltd
Original Assignee
Compugen Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compugen Ltd filed Critical Compugen Ltd
Priority to EP02741129A priority Critical patent/EP1417310A2/en
Priority to AU2002314491A priority patent/AU2002314491A1/en
Publication of WO2002102848A2 publication Critical patent/WO2002102848A2/en
Anticipated expiration legal-status Critical
Publication of WO2002102848A3 publication Critical patent/WO2002102848A3/en
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention concerns novel nucleic acid sequences and amino acid sequences of a novel variant of vascular endothelial growth factor (VEGF). The invention further concerns expression vectors and host cells containing said sequences as well as pharmaceutical compositions and detection methods using said sequences.
PCT/IL2002/000491 2001-06-20 2002-06-20 Nucleic acid and amino acid sequences of a vegf variant Ceased WO2002102848A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02741129A EP1417310A2 (en) 2001-06-20 2002-06-20 Nucleic acid and amino acid sequences of a vegf variant
AU2002314491A AU2002314491A1 (en) 2001-06-20 2002-06-20 Nucleic acid and amino acid sequences of a vegf variant

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88450101A 2001-06-20 2001-06-20
US09/884,O5O 2001-06-20

Publications (2)

Publication Number Publication Date
WO2002102848A2 WO2002102848A2 (en) 2002-12-27
WO2002102848A3 true WO2002102848A3 (en) 2004-03-04

Family

ID=25384758

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2002/000491 Ceased WO2002102848A2 (en) 2001-06-20 2002-06-20 Nucleic acid and amino acid sequences of a vegf variant

Country Status (3)

Country Link
EP (1) EP1417310A2 (en)
AU (1) AU2002314491A1 (en)
WO (1) WO2002102848A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106349389B (en) * 2015-07-21 2019-11-15 科济生物医药（上海）有限公司 Tumor-specific anti-EGFR antibody and its application

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11178593A (en) * 1997-12-24 1999-07-06 Fujirebio Inc VEGF121-specific monoclonal antibody and measurement method
WO1999040197A2 (en) * 1998-02-06 1999-08-12 Collateral Therapeutics, Inc. Variants of the angiogenic factor vascular endothelial cell growth factor: vegf

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11178593A (en) * 1997-12-24 1999-07-06 Fujirebio Inc VEGF121-specific monoclonal antibody and measurement method
WO1999040197A2 (en) * 1998-02-06 1999-08-12 Collateral Therapeutics, Inc. Variants of the angiogenic factor vascular endothelial cell growth factor: vegf

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EBI; 18 April 1997 (1997-04-18), XP002231091, Database accession no. AA350839 *
DATABASE EMBL [online] EBI; 7 January 2000 (2000-01-07), XP002231090, Database accession no. AL136131 *
NIELSEN H J ET AL: "Soluble vascular endothelial growth factor in various blood transfusion components.", TRANSFUSION (BETHESDA), vol. 39, no. 10, October 1999 (1999-10-01), pages 1078 - 1083, XP002231275, ISSN: 0041-1132 *
ONO KATSUAKI ET AL: "Structural features in heparin that interact with VEGF165 and modulate its biological activity.", GLYCOBIOLOGY, vol. 9, no. 7, July 1999 (1999-07-01), pages 705 - 711, XP009006033, ISSN: 0959-6658 *
PALEY PAMELA J ET AL: "Vascular endothelial growth factor expression in early stage ovarian carcinoma.", CANCER, vol. 80, no. 1, 1997, pages 98 - 106, XP002231274, ISSN: 0008-543X *
PATENT ABSTRACTS OF JAPAN vol. 1999, no. 12 29 October 1999 (1999-10-29) *
ROBINSON C J ET AL: "THE SPLICE VARIANTS OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) AND THEIR RECEPTORS", JOURNAL OF CELL SCIENCE, ESSEX, GB, vol. 114, no. PART 5, March 2001 (2001-03-01), pages 853 - 865, XP001105017 *

Also Published As

Publication number Publication date
EP1417310A2 (en) 2004-05-12
AU2002314491A1 (en) 2003-01-02
WO2002102848A2 (en) 2002-12-27

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