WO2003095651A1 - Procede de production d'acide mevalonique - Google Patents

Procede de production d'acide mevalonique Download PDF

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Publication number
WO2003095651A1
WO2003095651A1 PCT/JP2003/005765 JP0305765W WO03095651A1 WO 2003095651 A1 WO2003095651 A1 WO 2003095651A1 JP 0305765 W JP0305765 W JP 0305765W WO 03095651 A1 WO03095651 A1 WO 03095651A1
Authority
WO
WIPO (PCT)
Prior art keywords
mevalonic acid
microorganism
coa
acetyl
producing mevalonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2003/005765
Other languages
English (en)
French (fr)
Inventor
Kazuhiko Tabata
Shin-Ichi Hashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to EP03728047A priority Critical patent/EP1510583A1/en
Priority to AU2003234790A priority patent/AU2003234790A1/en
Priority to US10/513,759 priority patent/US20050287655A1/en
Priority to JP2004508516A priority patent/JPWO2003095651A1/ja
Publication of WO2003095651A1 publication Critical patent/WO2003095651A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
PCT/JP2003/005765 2002-05-10 2003-05-08 Procede de production d'acide mevalonique Ceased WO2003095651A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP03728047A EP1510583A1 (en) 2002-05-10 2003-05-08 Process for producing mevalonic acid
AU2003234790A AU2003234790A1 (en) 2002-05-10 2003-05-08 Process for producing mevalonic acid
US10/513,759 US20050287655A1 (en) 2002-05-10 2003-05-08 Process for producing mevalonic acid
JP2004508516A JPWO2003095651A1 (ja) 2002-05-10 2003-05-08 メバロン酸の製造方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002135073 2002-05-10
JP2002-135073 2002-05-10

Publications (1)

Publication Number Publication Date
WO2003095651A1 true WO2003095651A1 (fr) 2003-11-20

Family

ID=29416731

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2003/005765 Ceased WO2003095651A1 (fr) 2002-05-10 2003-05-08 Procede de production d'acide mevalonique

Country Status (5)

Country Link
US (1) US20050287655A1 (ja)
EP (1) EP1510583A1 (ja)
JP (1) JPWO2003095651A1 (ja)
AU (1) AU2003234790A1 (ja)
WO (1) WO2003095651A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107418978A (zh) * 2017-06-24 2017-12-01 天津大学 一种利用生物柴油副产物制备金合欢烯的方法
JP2018502059A (ja) * 2014-11-12 2018-01-25 ビゾリス インコーポレイテッド メバロノラクトンから調製されるポリマーおよび誘導体

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US8673601B2 (en) 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
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US20090111154A1 (en) * 2007-04-04 2009-04-30 The Regents Of The University Of California Butanol production by recombinant microorganisms
EP2171085A4 (en) 2007-06-01 2010-07-14 Sapphire Energy SCREENING OF GENETICALLY MODIFIED PHOTOSYNTHETIC ORGANISMS WITH HIGH THROUGHPUT
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
US8026386B2 (en) 2007-08-10 2011-09-27 Genomatica, Inc. Methods for the synthesis of olefins and derivatives
CA2698289A1 (en) * 2007-09-11 2009-03-19 Sapphire Energy, Inc. Methods of producing organic products with photosynthetic organisms and products and compositions thereof
AU2008299020A1 (en) * 2007-09-11 2009-03-19 Sapphire Energy, Inc. Molecule production by photosynthetic organisms
BRPI0817545A2 (pt) * 2007-10-12 2014-11-25 Univ California Microorganismo recombinante, métodos para produzir um microorganismo recombinante e para produzir isopropanol, vetor recombinante, e, célula hospedeira recombinante.
AU2008334945C1 (en) * 2007-12-13 2013-09-05 Danisco Us Inc. Compositions and methods for producing isoprene
CA2712779C (en) 2008-01-22 2021-03-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
DK2262901T3 (en) 2008-03-05 2019-01-21 Genomatica Inc ORGANISMS PRODUCING PRIMARY ALCOHOL
ES2656790T3 (es) 2008-03-27 2018-02-28 Genomatica, Inc. Microorganismos para la producción de ácido adípico y otros compuestos
AU2009240505B2 (en) 2008-04-23 2013-09-05 Danisco Us Inc. Isoprene synthase variants for improved microbial production of isoprene
WO2009135074A2 (en) * 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
BRPI0913901A2 (pt) 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
EP3514242A3 (en) 2008-09-10 2019-08-28 Genomatica, Inc. Microrganisms for the production of 1,4-butanediol
EP2337845A1 (en) * 2008-09-15 2011-06-29 Danisco US Inc. Increased isoprene production using mevalonate kinase and isoprene synthase
CA2737158A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Increased isoprene production using the archaeal lower mevalonate pathway
EP2373781A4 (en) 2008-12-16 2012-10-10 Genomatica Inc MICRO-ORGANISMS AND METHODS OF CONVERTING SYNGAS AND OTHER CARBON RESOURCES IN USEFUL PRODUCTS
AU2010238770A1 (en) * 2009-04-23 2011-11-03 Danisco Us Inc. Three-dimensional structure of isoprene synthase and its use thereof for generating variants
MY176050A (en) 2009-04-30 2020-07-22 Genomatica Inc Organisms for the production of 1,3-butanediol
BRPI1013505A2 (pt) 2009-04-30 2018-02-14 Genomatica Inc organismos para a produção de isopropanol, n-butanol, e isobutanol
EP2427544B1 (en) 2009-05-07 2019-07-17 Genomatica, Inc. Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid
JP2012526561A (ja) 2009-05-15 2012-11-01 ゲノマチカ， インク． シクロヘキサノンの産生のための生物
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LT2438036T (lt) 2009-06-04 2017-06-26 Genomatica, Inc. Fermentacijos sultinio komponentų išskyrimo būdas
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EP3190174A1 (en) 2009-08-05 2017-07-12 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
US8715971B2 (en) 2009-09-09 2014-05-06 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol
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KR20180014240A (ko) 2009-10-23 2018-02-07 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
KR20120120493A (ko) 2009-12-10 2012-11-01 게노마티카 인코포레이티드 합성 가스 또는 기타 가스상 탄소원 및 메탄올을 1,3-부탄디올로 변환하는 방법 및 변환용 유기체
EP2857518A3 (en) 2009-12-23 2015-04-22 Danisco US Inc. Compositions and methods of PGL for the increased production of isoprene
JP2013517796A (ja) 2010-01-29 2013-05-20 ジェノマティカ・インコーポレイテッド ｐ−トルイル酸およびテレフタル酸を生合成するための方法および微生物
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
CA2797409C (en) 2010-05-05 2019-12-24 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
PH12013500158A1 (en) 2010-07-26 2013-03-11 Genomatica Inc Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
CA2816306A1 (en) 2010-10-27 2012-05-03 Danisco Us Inc. Isoprene synthase variants for improved production of isoprene
BR112013027555A2 (pt) 2011-04-29 2021-08-10 Danisco Us Inc. células recombinantes capazes de maior produção de isopreno, mevalonato e isoprenoides e método para produzir isopreno, mevalonato e isoprenoides
SG194691A1 (en) 2011-04-29 2013-12-30 Danisco Us Inc Production of mevalonate, isoprene, and isoprenoids using genes encodingpolypeptides having thiolase, hmg-coa synthase and hmg-coa reductase enzymatic activities
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ES2735331T3 (es) 2013-04-10 2019-12-18 Goodyear Tire & Rubber Fosfocetolasas para mejorar la producción de metabolitos derivados de acetil-coenzima A, isopreno, precursores de isoprenoides e isoprenoides
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KR102745457B1 (ko) * 2019-09-25 2024-12-23 한국생명공학연구원 메탄으로부터 탄소 수 4 이상인 화합물을 생산하는 방법 및 조성물
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WO2001042476A1 (fr) * 1999-12-08 2001-06-14 Haruo Seto Genes a origine actinomycete d'enzymes intervenant dans la voie du mevalonate

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Patent Citations (1)

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WO2001042476A1 (fr) * 1999-12-08 2001-06-14 Haruo Seto Genes a origine actinomycete d'enzymes intervenant dans la voie du mevalonate

Non-Patent Citations (2)

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Title
BOLOTIN ALEXANDER ET AL.: "The complete genome sequence of the lactic acid bacterium lactococcus lactis ssp. lactis IL1403", GENOME RESEARCH, vol. 11, no. 5, 2001, pages 731 - 753, XP001109416 *
WILDING E. IMOGEN ET AL.: "Identification, evolution and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci", JOURNAL OF BACTERIOLOGY, vol. 182, no. 15, 2000, pages 4319 - 4327, XP002232852 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018502059A (ja) * 2014-11-12 2018-01-25 ビゾリス インコーポレイテッド メバロノラクトンから調製されるポリマーおよび誘導体
CN107418978A (zh) * 2017-06-24 2017-12-01 天津大学 一种利用生物柴油副产物制备金合欢烯的方法

Also Published As

Publication number Publication date
JPWO2003095651A1 (ja) 2005-09-15
EP1510583A1 (en) 2005-03-02
AU2003234790A1 (en) 2003-11-11
US20050287655A1 (en) 2005-12-29

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