WO2004009834A3 - Novel nucleic acids and secreted polypeptides - Google Patents

Novel nucleic acids and secreted polypeptides Download PDF

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Publication number
WO2004009834A3
WO2004009834A3 PCT/US2002/022858 US0222858W WO2004009834A3 WO 2004009834 A3 WO2004009834 A3 WO 2004009834A3 US 0222858 W US0222858 W US 0222858W WO 2004009834 A3 WO2004009834 A3 WO 2004009834A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
novel nucleic
secreted polypeptides
novel
secreted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/022858
Other languages
French (fr)
Other versions
WO2004009834A2 (en
Inventor
Y Tom Tang
Yonghong Yang
Gezhi Weng
Jie Zhang
Feiyan Ren
Aidong Xue
Jian-Rui Wang
Tom Wehrman
Malabika J Ghosh
Dunrui Wang
Qing A Zhao
Zhiwei Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuvelo Inc
Original Assignee
Nuvelo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuvelo Inc filed Critical Nuvelo Inc
Priority to EP02807515A priority Critical patent/EP1578989A2/en
Priority to AU2002368010A priority patent/AU2002368010A1/en
Priority to CA002453344A priority patent/CA2453344A1/en
Anticipated expiration legal-status Critical
Publication of WO2004009834A2 publication Critical patent/WO2004009834A2/en
Publication of WO2004009834A3 publication Critical patent/WO2004009834A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6432—Coagulation factor Xa (3.4.21.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21006—Coagulation factor Xa (3.4.21.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
PCT/US2002/022858 2001-07-21 2002-07-19 Novel nucleic acids and secreted polypeptides Ceased WO2004009834A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP02807515A EP1578989A2 (en) 2001-07-21 2002-07-19 Novel nucleic acids and secreted polypeptides
AU2002368010A AU2002368010A1 (en) 2001-07-21 2002-07-19 Novel nucleic acids and secreted polypeptides
CA002453344A CA2453344A1 (en) 2001-07-21 2002-07-19 Novel nucleic acids and secreted polypeptides

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US30697101P 2001-07-21 2001-07-21
US60/306,971 2001-07-21
US10/112,944 2002-03-28
US10/112,944 US20040048249A1 (en) 2000-01-21 2002-03-28 Novel nucleic acids and secreted polypeptides

Publications (2)

Publication Number Publication Date
WO2004009834A2 WO2004009834A2 (en) 2004-01-29
WO2004009834A3 true WO2004009834A3 (en) 2007-09-20

Family

ID=30772439

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/022858 Ceased WO2004009834A2 (en) 2001-07-21 2002-07-19 Novel nucleic acids and secreted polypeptides

Country Status (4)

Country Link
US (1) US20040048249A1 (en)
EP (1) EP1578989A2 (en)
AU (1) AU2002368010A1 (en)
WO (1) WO2004009834A2 (en)

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WO2000012758A1 (en) * 1998-09-02 2000-03-09 Diadexus Llc A novel method of diagnosing, monitoring, staging, imaging and treating various cancers
CA2407937A1 (en) * 2000-05-05 2001-11-15 Merck Patent Gesellschaft Mit Beschraenkter Haftung New ras guanine-nucleotide-exchange factor 1 (nrg1)
US8044259B2 (en) * 2000-08-03 2011-10-25 The Regents Of The University Of Michigan Determining the capability of a test compound to affect solid tumor stem cells
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
US7265210B2 (en) * 2000-09-15 2007-09-04 Genentech, Inc. Anti-PRO9821 antibodies
US20030108915A1 (en) * 2000-10-20 2003-06-12 University Of Medicine & Dentistry Of New Jersey Glioblastoma multiforme associated protein GliTEN
IL155800A0 (en) * 2000-11-09 2003-12-23 Univ Virginia Nucleic acid sequences encoding human testis specific kinases
AU2002230904A1 (en) * 2000-12-21 2002-07-01 New York University A transmembrane protein as a downstream target of neurotrophin and ephrin receptor tyrosine kinases, dna encoding same monoclonal antibodies thereto
US6500655B1 (en) * 2001-02-01 2002-12-31 Applera Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
US6733992B2 (en) * 2001-02-21 2004-05-11 Applera Corporation Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof
US20030211039A1 (en) * 2001-05-29 2003-11-13 Macina Roberto A. Method of diagnosing, monitoring, staging, imaging and treating colon cancer
AU2002339946A1 (en) * 2001-09-19 2003-04-01 The Goverment Of The United States Of America, Represented By The Secretary, Dept. Of Health And Hum Maxp1
US20040038267A1 (en) * 2001-12-19 2004-02-26 Neil Burford Intracellular signaling molecules
AU2003221433A1 (en) * 2002-03-19 2003-09-29 Daiichi Pharmaceutical Co., Ltd. POLYPEPTIDES BINDING TO HUMAN SYNTAXIN 1a
US7294704B2 (en) * 2003-08-15 2007-11-13 Diadexus, Inc. Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk
US20050120396A1 (en) * 2003-08-22 2005-06-02 Atherogenics, Inc. Human MEKK1 protein and nucleic acid molecules and uses therefor
US7910540B2 (en) * 2004-06-10 2011-03-22 Zymogenetics, Inc. Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation
EP2479277B1 (en) * 2004-07-22 2015-09-02 Five Prime Therapeutics, Inc. Use of MGD-CSF in a method of treatment of Alzheimer's disease.
WO2006076288A2 (en) * 2005-01-11 2006-07-20 Five Prime Therapeutics, Inc. Dna constructs for long-term expression of intravascularly injected naked dna
JP2009517002A (en) * 2005-04-06 2009-04-30 ヴェレニウム コーポレイション Enzymes and formulations for broad-specific decontamination of chemical and biological weapons
US20070249533A1 (en) * 2005-09-28 2007-10-25 Levin Steven D Il-17a and il-17f antagonists and methods of using the same
CA2628221A1 (en) 2005-10-31 2007-05-10 Oncomed Pharmaceuticals, Inc. Anti-frizzled receptor antibodies for treating cancer
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
US20070142288A1 (en) * 2005-12-20 2007-06-21 Pappachan Kolattukudy Isolated MCPIP and methods of use
US20080019961A1 (en) * 2006-02-21 2008-01-24 Regents Of The University Of Michigan Hedgehog signaling pathway antagonist cancer treatment
GB0614682D0 (en) * 2006-07-24 2006-08-30 Ares Trading Sa Proteins
US20110002981A1 (en) * 2006-12-20 2011-01-06 Kolattukudy Pappachan E MCPIP Protection Against Cardiac Dysfunction
WO2008092002A2 (en) 2007-01-24 2008-07-31 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing pancreatic cancer
US7790676B2 (en) 2007-03-28 2010-09-07 Zymogenetics, Inc. Soluble IL-17RA/RC fusion proteins
SG190568A1 (en) 2008-09-26 2013-06-28 Oncomed Pharm Inc Frizzled-binding agents and uses thereof
WO2011081667A1 (en) * 2009-12-31 2011-07-07 Immunitor USA, Inc. Composition for atherosclerosis, obesity and obesity-related disorders
TWI535445B (en) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Wnt antagonists and methods of treatment and screening
CA2794674A1 (en) 2010-04-01 2011-10-06 Oncomed Pharmaceuticals, Inc. Frizzled-binding agents and uses thereof
PL2563920T3 (en) 2010-04-29 2017-08-31 Ionis Pharmaceuticals, Inc. Modulation of transthyretin expression
AU2013334790A1 (en) 2012-10-23 2015-04-30 Oncomed Pharmaceuticals, Inc. Methods of treating neuroendocrine tumors using Wnt pathway-binding agents
AU2014212081A1 (en) 2013-02-04 2015-08-13 Oncomed Pharmaceuticals, Inc. Methods and monitoring of treatment with a Wnt pathway inhibitor
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
US10272137B2 (en) * 2013-06-27 2019-04-30 The Board Of Regents Of The University Of Texas System Compositions and methods relating to myomaker-induced muscle cell fusion
CA3051839A1 (en) 2017-02-17 2018-08-23 Bristol-Myers Squibb Company Antibodies to alpha-synuclein and uses thereof
EP3807304A1 (en) 2018-06-15 2021-04-21 Children's Hospital Medical Center Polypeptides, nucleic acid molecules, compositions, and related methods
WO2021011561A1 (en) * 2019-07-15 2021-01-21 The General Hospital Corporation Zebrafish deletion and compound mutants and uses thereof
JP7684523B2 (en) * 2021-12-21 2025-05-27 エスアールアイ インターナショナル Dual targeting for cell-specific delivery to the central nervous system
US20240247301A1 (en) * 2022-12-06 2024-07-25 Ohio State Innovation Foundation Diagnostic assay for classic inborn galactosemia

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998056804A1 (en) * 1997-06-13 1998-12-17 Human Genome Sciences, Inc. 86 human secreted proteins

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WO2002036754A2 (en) * 2000-10-31 2002-05-10 Bayer Aktiengesellschaft Nucleotide and polypeptide sequence of human lysosomal acid lipase
US20020193303A1 (en) * 2001-01-25 2002-12-19 Millennium Pharmaceuticals, Inc. 58860, a human cholesteryl ester hydrolase and uses therefor

Patent Citations (1)

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WO1998056804A1 (en) * 1997-06-13 1998-12-17 Human Genome Sciences, Inc. 86 human secreted proteins

Also Published As

Publication number Publication date
WO2004009834A2 (en) 2004-01-29
US20040048249A1 (en) 2004-03-11
AU2002368010A1 (en) 2004-02-09
EP1578989A2 (en) 2005-09-28
AU2002368010A8 (en) 2004-02-09

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