WO2004024769A3 - Ostertagia vaccine - Google Patents

Ostertagia vaccine Download PDF

Info

Publication number
WO2004024769A3
WO2004024769A3 PCT/EP2003/010189 EP0310189W WO2004024769A3 WO 2004024769 A3 WO2004024769 A3 WO 2004024769A3 EP 0310189 W EP0310189 W EP 0310189W WO 2004024769 A3 WO2004024769 A3 WO 2004024769A3
Authority
WO
WIPO (PCT)
Prior art keywords
proteins
parts
nucleic acid
acid sequences
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2003/010189
Other languages
French (fr)
Other versions
WO2004024769A2 (en
Inventor
Peter Geldhof
Isabel Vercauteren
Edwin Claerebout
Jozef Vercruysse
Maere Veerle De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universiteit Gent
Original Assignee
Universiteit Gent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES03750540T priority Critical patent/ES2304526T3/en
Priority to CA2498249A priority patent/CA2498249C/en
Priority to DE60320425T priority patent/DE60320425T2/en
Priority to US10/527,771 priority patent/US7264812B2/en
Priority to BR0314258-2A priority patent/BR0314258A/en
Priority to BRPI0314258-2A priority patent/BRPI0314258B1/en
Priority to AU2003270190A priority patent/AU2003270190B2/en
Priority to EP03750540A priority patent/EP1539820B1/en
Application filed by Universiteit Gent filed Critical Universiteit Gent
Publication of WO2004024769A2 publication Critical patent/WO2004024769A2/en
Publication of WO2004024769A3 publication Critical patent/WO2004024769A3/en
Anticipated expiration legal-status Critical
Priority to US11/832,836 priority patent/US7718179B2/en
Priority to US12/761,923 priority patent/US8227584B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C07K14/4354—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855—Proteins from animals other than mammals or birds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to nucleic acid sequences encoding Ostertagia ostertagi proteins and to parts of such nucleic acid sequences that encode an immunogenic fragment of such proteins, and to DNA fragments, recombinant DNA molecules, live recombinant carriers and host cells comprising such nucleic acid sequences or such parts thereof. The invention also relates to Ostertagia ostertagi proteins and immunogenic parts thereof encoded by such sequences. Furthermore, the present invention relates to vaccines comprising such nucleic acid sequences and parts thereof, DNA fragments, recombinant DNA molecules, live recombinant carriers and host cells comprising such nucleic acid sequences or such parts thereof, proteins or immunogenic parts thereof and antibodies against such proteins or immunogenic parts thereof. Also, the invention relates to the use of said proteins in vaccines and for the manufacture of vaccines. Moreover, the invention relates to the use of aid nucleic acid sequences, proteins or antibodies for diagnostic or vaccination purposes. Finally the invention relates to diagnostic kits comprising such nucleic acids, proteins or antibodies against such proteins.
PCT/EP2003/010189 2002-09-13 2003-09-11 Ostertagia vaccine Ceased WO2004024769A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
AU2003270190A AU2003270190B2 (en) 2002-09-13 2003-09-11 Ostertagia vaccine
DE60320425T DE60320425T2 (en) 2002-09-13 2003-09-11 Ostertagia VACCINE
US10/527,771 US7264812B2 (en) 2002-09-13 2003-09-11 Ostertagia vaccine
BR0314258-2A BR0314258A (en) 2002-09-13 2003-09-11 Nucleic acid sequence, DNA fragment, recombinant DNA molecule, living recombinant vehicle, host cell, ostertagi ostertagi protein or an immunogenic fragment of said protein, use, vaccine to combat ostertagia ostertagi infection, method for preparing a vaccine and diagnostic kit
BRPI0314258-2A BRPI0314258B1 (en) 2002-09-13 2003-09-11 NUCLEIC ACID SEQUENCE, DNA FRAGMENT, RECOMBINANT DNA MOLECULE, VECTOR, MICROBIAN HOST CELL, USE OF THE SAME, OSTERTAGI INFECTION INFECTION, METHOD FOR PREPARATION, KACTIC DIAGNOSIS
ES03750540T ES2304526T3 (en) 2002-09-13 2003-09-11 OSTERTAGIA VACCINE.
CA2498249A CA2498249C (en) 2002-09-13 2003-09-11 Ostertagia vaccine
EP03750540A EP1539820B1 (en) 2002-09-13 2003-09-11 Ostertagia vaccine
US11/832,836 US7718179B2 (en) 2002-09-13 2007-08-02 Ostertagia vaccine
US12/761,923 US8227584B2 (en) 2002-09-13 2010-04-16 Ostertagia vaccine

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/243,319 US20040052817A1 (en) 2002-09-13 2002-09-13 Ostertagia vaccine
US10/243,319 2002-09-13

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US10/243,319 Continuation-In-Part US20040052817A1 (en) 2002-09-13 2002-09-13 Ostertagia vaccine

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US10527771 A-371-Of-International 2003-09-11
US11/832,836 Continuation US7718179B2 (en) 2002-09-13 2007-08-02 Ostertagia vaccine
US12/761,923 Division US8227584B2 (en) 2002-09-13 2010-04-16 Ostertagia vaccine

Publications (2)

Publication Number Publication Date
WO2004024769A2 WO2004024769A2 (en) 2004-03-25
WO2004024769A3 true WO2004024769A3 (en) 2004-06-03

Family

ID=31991608

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/010189 Ceased WO2004024769A2 (en) 2002-09-13 2003-09-11 Ostertagia vaccine

Country Status (11)

Country Link
US (4) US20040052817A1 (en)
EP (1) EP1539820B1 (en)
AR (1) AR041243A1 (en)
AT (1) ATE392435T1 (en)
AU (1) AU2003270190B2 (en)
BR (2) BRPI0314258B1 (en)
CA (1) CA2498249C (en)
DE (1) DE60320425T2 (en)
ES (1) ES2304526T3 (en)
NZ (1) NZ542733A (en)
WO (1) WO2004024769A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003267876A1 (en) * 2002-09-13 2004-04-30 Ovita Limited Aspartyl protease inhibitor as a nematode allergen
US20040052817A1 (en) * 2002-09-13 2004-03-18 Peter Geldhof Ostertagia vaccine
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995009182A1 (en) * 1993-09-28 1995-04-06 The University Of Melbourne Protective antigens against parasites

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB894603A (en) * 1959-09-02 1962-04-26 Allen & Hanburys Ltd Improvements in or relating to vaccines
US5753787A (en) * 1995-04-10 1998-05-19 Yale University Nucleic acids encoding ancylostoma secreted protein
US5759782A (en) * 1995-06-07 1998-06-02 The United States Of America Cellular apoptosis susceptibility protein (CSP) and antisense CSP
US6017757A (en) * 1997-02-20 2000-01-25 Mississippi State University Isolated viable nematode intestinal cells
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
US20040052817A1 (en) * 2002-09-13 2004-03-18 Peter Geldhof Ostertagia vaccine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995009182A1 (en) * 1993-09-28 1995-04-06 The University Of Melbourne Protective antigens against parasites

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEN JENG-SHONG ET AL: "Extensive sequence conservation among insect, nematode, and vertebrate vitellogenins reveals ancient common ancestry", JOURNAL OF MOLECULAR EVOLUTION, vol. 44, no. 4, 1997, pages 440 - 451, XP002264414, ISSN: 0022-2844 *
DATABASE EMBL [online] 14 May 2001 (2001-05-14), XP002264416, accession no. EMBL Database accession no. BG733986 *
DATABASE EMBL [online] 31 March 2001 (2001-03-31), XP002264415, accession no. EMBL Database accession no. AJ310819 *
VERCAUTEREN ISABEL ET AL: "Identification of excretory-secretory products of larval and adult Ostertagia ostertagi by immunoscreening of cDNA libraries.", MOLECULAR AND BIOCHEMICAL PARASITOLOGY. NETHERLANDS FEB 2003, vol. 126, no. 2, February 2003 (2003-02-01), pages 201 - 208, XP001156729, ISSN: 0166-6851 *

Also Published As

Publication number Publication date
WO2004024769A2 (en) 2004-03-25
DE60320425T2 (en) 2008-07-31
US20040052817A1 (en) 2004-03-18
AU2003270190A1 (en) 2004-04-30
CA2498249A1 (en) 2004-03-25
US20100209446A1 (en) 2010-08-19
US8227584B2 (en) 2012-07-24
DE60320425D1 (en) 2008-05-29
EP1539820B1 (en) 2008-04-16
US7264812B2 (en) 2007-09-04
CA2498249C (en) 2016-09-06
US7718179B2 (en) 2010-05-18
BRPI0314258B1 (en) 2019-07-09
ES2304526T3 (en) 2008-10-16
EP1539820A2 (en) 2005-06-15
US20090028892A1 (en) 2009-01-29
AR041243A1 (en) 2005-05-11
NZ542733A (en) 2007-06-29
BR0314258A (en) 2005-07-26
ATE392435T1 (en) 2008-05-15
AU2003270190B2 (en) 2008-09-04
US20050271683A1 (en) 2005-12-08

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