WO2004029261A3 - Production of canthaxanthin by phaffia - Google Patents

Production of canthaxanthin by phaffia Download PDF

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Publication number
WO2004029261A3
WO2004029261A3 PCT/EP2003/010294 EP0310294W WO2004029261A3 WO 2004029261 A3 WO2004029261 A3 WO 2004029261A3 EP 0310294 W EP0310294 W EP 0310294W WO 2004029261 A3 WO2004029261 A3 WO 2004029261A3
Authority
WO
WIPO (PCT)
Prior art keywords
phaffia
canthaxanthin
production
recombinant microorganism
echinenone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2003/010294
Other languages
French (fr)
Other versions
WO2004029261A2 (en
Inventor
Tatsuo Hoshino
Kazuyuki Ojima
Yutaka Setoguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Priority to AU2003267371A priority Critical patent/AU2003267371A1/en
Priority to EP03748041A priority patent/EP1543132A2/en
Priority to JP2004538914A priority patent/JP2006500046A/en
Priority to US10/528,846 priority patent/US20060141557A1/en
Publication of WO2004029261A2 publication Critical patent/WO2004029261A2/en
Publication of WO2004029261A3 publication Critical patent/WO2004029261A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Disclosed is a process for producing canthaxanthin and echinenone which comprises cultivating a recombinant microorganism which is expressing a ß-carotene ketolase gene and belonging to the genus Xanthophyllomyces (Phaffia) in an aqueous nutrient medium under aerobic conditions, and isolating the resulted carotenoids from the cells of said recombinant microorganism or from the cultured broth.
PCT/EP2003/010294 2002-09-27 2003-09-16 Production of canthaxanthin by phaffia Ceased WO2004029261A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2003267371A AU2003267371A1 (en) 2002-09-27 2003-09-16 Production of canthaxanthin by phaffia
EP03748041A EP1543132A2 (en) 2002-09-27 2003-09-16 Production of canthaxanthin by phaffia
JP2004538914A JP2006500046A (en) 2002-09-27 2003-09-16 Method for producing canthaxanthin by Phaffia
US10/528,846 US20060141557A1 (en) 2002-09-27 2003-09-16 Production of canthaxanthin by phaffia

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02021600.8 2002-09-27
EP02021600 2002-09-27

Publications (2)

Publication Number Publication Date
WO2004029261A2 WO2004029261A2 (en) 2004-04-08
WO2004029261A3 true WO2004029261A3 (en) 2004-05-27

Family

ID=32039097

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/010294 Ceased WO2004029261A2 (en) 2002-09-27 2003-09-16 Production of canthaxanthin by phaffia

Country Status (6)

Country Link
US (1) US20060141557A1 (en)
EP (1) EP1543132A2 (en)
JP (1) JP2006500046A (en)
CN (1) CN1788091A (en)
AU (1) AU2003267371A1 (en)
WO (1) WO2004029261A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8691555B2 (en) 2006-09-28 2014-04-08 Dsm Ip Assests B.V. Production of carotenoids in oleaginous yeast and fungi
US10240215B2 (en) 2010-03-15 2019-03-26 Jx Nippon Oil & Energy Corporation Method for producing astaxanthin by fermentation

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006227165B2 (en) 2005-03-18 2011-11-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
CN110607305A (en) * 2019-08-30 2019-12-24 海南大学 Zebrafish α7 acetylcholine receptor recombinant vector and recombinant cells
CN112063539A (en) * 2020-09-16 2020-12-11 厦门昶青生物科技有限公司 Culture medium and culture method for producing carotenoid by fermentation of phaffia rhodozyma
JP2022101424A (en) * 2020-12-24 2022-07-06 オークバイオ インコーポレイテッド Methods for producing biochemicals using enzyme genes derived from brevundimonas strain and compositions made thereby

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1111067A2 (en) * 1999-12-01 2001-06-27 F. Hoffmann-La Roche Ag Recombinant production of carotenoids, particularly astaxanthin
US6291204B1 (en) * 1996-12-02 2001-09-18 Roche Vitamins Inc. Fermentative carotenoid production
US6365386B1 (en) * 1999-03-09 2002-04-02 Roche Vitamins Inc. Astaxanthin synthase

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6291204B1 (en) * 1996-12-02 2001-09-18 Roche Vitamins Inc. Fermentative carotenoid production
US6365386B1 (en) * 1999-03-09 2002-04-02 Roche Vitamins Inc. Astaxanthin synthase
EP1111067A2 (en) * 1999-12-01 2001-06-27 F. Hoffmann-La Roche Ag Recombinant production of carotenoids, particularly astaxanthin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MISAWA NORIHIKO ET AL: "Canthaxanthin biosynthesis by the conversion of methylene to keto groups in a hydrocarbon beta-carotene by a single gene", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 209, no. 3, 1995, pages 867 - 876, XP002264744, ISSN: 0006-291X *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8691555B2 (en) 2006-09-28 2014-04-08 Dsm Ip Assests B.V. Production of carotenoids in oleaginous yeast and fungi
US9297031B2 (en) 2006-09-28 2016-03-29 Dsm Ip Assets B.V. Production of carotenoids in oleaginous yeast and fungi
US10240215B2 (en) 2010-03-15 2019-03-26 Jx Nippon Oil & Energy Corporation Method for producing astaxanthin by fermentation

Also Published As

Publication number Publication date
JP2006500046A (en) 2006-01-05
WO2004029261A2 (en) 2004-04-08
US20060141557A1 (en) 2006-06-29
EP1543132A2 (en) 2005-06-22
AU2003267371A1 (en) 2004-04-19
CN1788091A (en) 2006-06-14
AU2003267371A8 (en) 2004-04-19

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